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1
المؤلفون: Monimoy Banerjee, Caitlin N. Kent, Penchala Narasimharao Meka, Subhabrata Chaudhury, Brian S. J. Blagg
المصدر: Chemistry
مصطلحات موضوعية: Gene isoform, Combination therapy, biology, Chemistry, Organic Chemistry, Cancer, General Chemistry, Computational biology, medicine.disease, Hsp90, Article, Catalysis, Design synthesis, Neoplasms, Heat shock protein, biology.protein, medicine, Humans, Protein Isoforms, Protein folding, HSP90 Heat-Shock Proteins, Heat shock, Molecular Chaperones, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8c36e98335a0e974b1aa2571c9c0d4Test
https://doi.org/10.1002/chem.202102574Test -
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المؤلفون: Leonard M. Neckers, John Koren, Kristin Beebe, Vitumbiko Munthali, Jeffrey M. Holzbeierlein, Brian S. J. Blagg, Weiya Liu, Sanket J. Mishra, John A. Taylor, Monimoy Banerjee, Caitlin N. Kent
المصدر: Journal of Medicinal Chemistry. 64:1545-1557
مصطلحات موضوعية: Gene isoform, 0303 health sciences, biology, Chemistry, Cancer, Small Molecule Libraries, medicine.disease, 01 natural sciences, Hsp90, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Heat shock protein, Drug Discovery, polycyclic compounds, Cancer research, medicine, biology.protein, Molecular Medicine, Structure–activity relationship, Gene silencing, Protein folding, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ae713e75838f258bcdb77b9f5d0cb66cTest
https://doi.org/10.1021/acs.jmedchem.0c01700Test -
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المؤلفون: Chitra Subramanian, Robert L. Matts, Brian S. J. Blagg, Anuj Khandelwal, Weiya Liu, Jeffery M. Holzbeierlein, Junpeng Deng, Mark S. Cohen, Victor W. Day, Sanket J. Mishra, Caitlin N. Kent, Maurie Balch, Shuxia Peng
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Gene isoform, Science, Drug Evaluation, Preclinical, General Physics and Astronomy, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Heat shock protein, polycyclic compounds, medicine, Humans, Protein Isoforms, Structure–activity relationship, HSP90 Heat-Shock Proteins, Heat shock, lcsh:Science, Multidisciplinary, biology, Chemistry, HEK 293 cells, Cancer, Hydrogen Bonding, General Chemistry, medicine.disease, Hsp90, 3. Good health, Cell biology, HEK293 Cells, 030104 developmental biology, Drug Design, biology.protein, Protein folding, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca0d3fd460c06cb7b268c988c06edc1Test
http://link.springer.com/article/10.1038/s41467-017-02013-1Test -
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المؤلفون: Brian S. J. Blagg, Katherine M. Byrd, Caitlin N. Kent
المصدر: ChemMedChem. 12:2022-2029
مصطلحات موضوعية: Stereochemistry, Triazole, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Article, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Amide, Stilbenes, Drug Discovery, medicine, Side chain, Humans, Molecule, Structure–activity relationship, HSP90 Heat-Shock Proteins, General Pharmacology, Toxicology and Pharmaceutics, Novobiocin, Cell Proliferation, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Organic Chemistry, Hsp90, 0104 chemical sciences, chemistry, biology.protein, Molecular Medicine, Piperidine, Drug Screening Assays, Antitumor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe51d71c54ecf5716dd75fd0a5317418Test
https://doi.org/10.1002/cmdc.201700630Test -
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المؤلفون: Daniel T. Gewirth, Nanette L.S. Que, Adam S. Duerfeldt, Brian S. J. Blagg, Jinbo Zhao, Caitlin N. Kent, Vincent M. Crowley
المصدر: Journal of medicinal chemistry. 61(7)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Stereochemistry, Substituent, Molecular Conformation, Crystallography, X-Ray, Insert (molecular biology), Article, 03 medical and health sciences, Residue (chemistry), chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Adenosine Triphosphate, Dogs, Drug Discovery, Imidazole, Animals, Humans, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, biology, Chemistry, Membrane Proteins, Ligand (biochemistry), Hsp90, 030104 developmental biology, Cytoplasm, 030220 oncology & carcinogenesis, Drug Design, biology.protein, Molecular Medicine, Structure based, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccca754a8ee05065988cd16059cab867Test
https://pubmed.ncbi.nlm.nih.gov/29528635Test -
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المؤلفون: Caitlin N. Kent, I. K. Guttilla Reed
المصدر: Clinicaltranslational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 18(11)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pathology, medicine.medical_specialty, Epithelial-Mesenchymal Transition, Biology, Metastasis, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Downregulation and upregulation, microRNA, medicine, Animals, Humans, Epithelial–mesenchymal transition, PI3K/AKT/mTOR pathway, Phosphoinositide 3-kinase, Endometrial cancer, General Medicine, medicine.disease, Endometrial Neoplasms, MicroRNAs, 030104 developmental biology, Oncology, Receptors, Estrogen, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Estrogen receptor alpha, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7972b3419cf290e94db35fa8e1af362cTest
https://pubmed.ncbi.nlm.nih.gov/26856598Test