المؤلفون: Emil Aalto-Setälä, Georgiy A. Belogurov, Jacob Bakermans, David L.V. Bauer, Anssi M. Malinen, Olena Parilova, David Dulin, Martin Blessing, Achillefs N. Kapanidis

المساهمون: Physics of Living Systems, LaserLaB - Molecular Biophysics

المصدر: Journal of Molecular Biology
Malinen, A M, Bakermans, J, Aalto-Setälä, E, Blessing, M, Bauer, D L V, Parilova, O, Belogurov, G A, Dulin, D & Kapanidis, A N 2022, ' Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway ', Journal of Molecular Biology, vol. 434, no. 2, 167383, pp. 1-18 . https://doi.org/10.1016/j.jmb.2021.167383Test
Journal of Molecular Biology, 434(2):167383, 1-18. Academic Press Inc.

مصطلحات موضوعية: RPi, RNAP–promoter intermediate complex, Models, Molecular, dsLC2, double-stranded consensus lac promoter, Transcription, Genetic, Protein Conformation, lac operon, σ factor, RNAP, RNA polymerase, chemistry.chemical_compound, Structural Biology, RNA polymerase, Fluorescence microscope, RL, rudder loop in the RNAP β′ subunit, cryo-EM, cryo-electron microscopy, Promoter Regions, Genetic, Transcription Initiation, Genetic, transcription initiation, ALEX, Alternating laser excitation, biology, DNA-Directed RNA Polymerases, GL, gate loop in the RNAP β subunit, molecular mechanism, ntDNA, non-template DNA, Genetics & Genomics, αCTD, C-terminal domain of RNA polymerase α-subunit, Research Article, Protein Binding, DNA, Bacterial, Model organisms, E*, apparent FRET efficiency, Myx, myxopyronin B, Immunology, RPO, RNAP–promoter open complex, tDNA, template DNA, Infectious Disease, total internal reflection fluorescence microscopy, Chemical kinetics, Escherichia coli, Molecular Biology, Transcription bubble, ComputingMethodologies_COMPUTERGRAPHICS, Computational & Systems Biology, LL, lid loop in the RNAP β′ subunit, FOS: Clinical medicine, Cryoelectron Microscopy, FRET, fluorescence energy transfer, Active site, Promoter, HMM, Hidden Markov modelling, reaction pathway, lacCONS, consensus lac promoter, CI, confidence interval, pmLC2, pre-melted consensus lac promoter, chemistry, Genes, Bacterial, RPC, RNAP–promoter closed complex, biology.protein, Biophysics, Nucleic Acid Conformation, Cor, corallopyronin A, Holoenzymes, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d45174421ad539b45f3f4ba85ff46caTest
https://research.vu.nl/en/publications/a6f8678f-2f44-48c2-a1c6-551c25cefd41Test

المؤلفون: Zhaoyuan Hou, Hai Gao, Liang Zhang, Pan Zhang, Houwen Lin, Lin Zhang

المصدر: Biochemical and Biophysical Research Communications. 586:1-7

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Genetic Vectors, Phosphoadenosine Phosphosulfate, Biophysics, Gene Expression, Phenylalanine, Crystallography, X-Ray, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Adenosine Triphosphate, Sulfation, Multienzyme Complexes, Catalytic Domain, Escherichia coli, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, chemistry.chemical_classification, Sequence Homology, Amino Acid, ATP synthase, biology, Drug discovery, Substrate (chemistry), Cell Biology, Recombinant Proteins, Sulfate Adenylyltransferase, Neoplasm Proteins, 3'-Phosphoadenosine-5'-phosphosulfate, Enzyme, chemistry, biology.protein, Thermodynamics, Protein Conformation, beta-Strand, Sequence Alignment, Function (biology), Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd5b658bcb55b0905877c0f5eaa23b0Test
https://doi.org/10.1016/j.bbrc.2021.11.062Test

المؤلفون: Eui-Jeon Woo, Yan An, Kyung-Mo Song, Byung-Ha Oh, Su-Jin Lee, Jong-Tae Park, Woo-Chan Ahn, Kwang-Hyun Park

المصدر: Biochemical and Biophysical Research Communications. 586:49-54

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Glycoside Hydrolases, Stereochemistry, Genetic Vectors, Biophysics, Gene Expression, Crystallography, X-Ray, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Residue (chemistry), Hydrolysis, Polysaccharides, Catalytic Domain, Escherichia coli, Protein Interaction Domains and Motifs, Cloning, Molecular, Molecular Biology, chemistry.chemical_classification, biology, Escherichia coli Proteins, Active site, Substrate (chemistry), Cell Biology, Protein engineering, Maltose, Maltodextrin, Recombinant Proteins, Glucose, Enzyme, chemistry, Biocatalysis, biology.protein, Protein Conformation, beta-Strand, Protein Multimerization, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fbaece6777e83987ef01a4ce30c562Test
https://doi.org/10.1016/j.bbrc.2021.11.070Test

المؤلفون: Xinyu Xu, Yi Lin, Wei Cheng, Dan Ke, Yujie Chen, Yuquan Wei, Jinzhu Zhang, Jie Zhou, Minghai Tang, Jianxiong He, Haohao Dong, Wenxian Yang, Xiaofeng Zhu, James H. Naismith

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Glycosylation, Glycobiology, General Physics and Astronomy, Gene Expression, Steviol, Protein Engineering, Substrate Specificity, chemistry.chemical_compound, 0302 clinical medicine, Glucosides, Catalytic Domain, Stevia, Plant Proteins, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Recombinant Proteins, Biochemistry, Carbohydrate Sequence, Taste, Enzyme mechanisms, Diterpenes, Kaurane, Steviol glycoside, Protein Binding, Uridine Diphosphate Glucose, Glycan, Science, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Glycosyltransferase, Humans, Protein Interaction Domains and Motifs, 030304 developmental biology, X-ray crystallography, Glycoside, Glycosyltransferases, Oryza, General Chemistry, Stevia rebaudiana, Kinetics, Enzyme, Aglycone, Glucose, chemistry, Sweetening Agents, biology.protein, Biocatalysis, Protein Conformation, beta-Strand, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537f0f7b9ff33f516d2e537af2a0991bTest
https://doaj.org/article/3992bcac521a4b928331e2b513baaeabTest

المؤلفون: Lixin Huang, Lei Zhang, Xiaonan Huang, Mingyue Gu, Zhangxin Chen, Ke He, Luqi Huang, Jie Deng, Zhenzhan Chang, Chao Shi, Juan Guo

المصدر: Biochemical and Biophysical Research Communications. 582:125-130

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Stereochemistry, Genetic Vectors, Biophysics, Gene Expression, Secondary Metabolism, Salvia miltiorrhiza, Crystal structure, Crystallography, X-Ray, Biochemistry, Substrate Specificity, Catalysis, Synthetic biology, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Biosynthesis, Escherichia coli, Protein Interaction Domains and Motifs, Cloning, Molecular, Molecular Biology, Plant Proteins, chemistry.chemical_classification, Binding Sites, biology, Chemistry, Substrate (chemistry), Cytochrome P450, Cell Biology, Recombinant Proteins, Enzyme, Abietanes, biology.protein, Protein Conformation, beta-Strand, Diterpenes, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772b9763107b874e55a5b8757a254bb6Test
https://doi.org/10.1016/j.bbrc.2021.10.004Test

المؤلفون: Jiwon Heo, Hyun Kyu Song, Leehyeon Kim, Jin Seok Shin, Si Hoon Park

المصدر: Biochemical and Biophysical Research Communications. 582:86-92

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Saccharomyces cerevisiae Proteins, Proline, Ubiquitin-Protein Ligases, Genetic Vectors, Saccharomyces cerevisiae, Vesicular Transport Proteins, Biophysics, GID complex, Gene Expression, Crystallography, X-Ray, Biochemistry, Substrate Specificity, Residue (chemistry), Escherichia coli, Protein Interaction Domains and Motifs, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, chemistry.chemical_classification, DNA ligase, Binding Sites, Sequence Homology, Amino Acid, biology, Substrate (chemistry), Cell Biology, biology.organism_classification, Recombinant Proteins, Yeast, Ubiquitin ligase, chemistry, Proteolysis, biology.protein, Protein Conformation, beta-Strand, Degron, Oligopeptides, Sequence Alignment, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79af5d1b009cd3ef96453985e257795dTest
https://doi.org/10.1016/j.bbrc.2021.10.007Test

المؤلفون: Laixing Zhang, Steven E. Jacobsen, Jiamu Du, Zhe Wu, C. Jake Harris, Sisi Li, Zhenhui Zhong, Qian Wang, Maojun Yang, Changshi Wang, Zhenlin Yang, Suhua Feng, Jixian Zhai, Yan Xue, Lifan Xiao

المصدر: Science

مصطلحات موضوعية: Models, Molecular, Ribonuclease III, Protein Conformation, Arabidopsis, Article, Protein Domains, Phosphorylation, RNA, Small Interfering, Multidisciplinary, biology, Arabidopsis Proteins, Chemistry, Mechanism (biology), Cryoelectron Microscopy, RNA, Cell biology, enzymes and coenzymes (carbohydrates), Mutagenesis, RNA, Plant, Transfer RNA, biology.protein, Nucleic Acid Conformation, Wafer dicing, Biogenesis, Protein Binding, Dicer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800f8507c52b4e79673c29e352f7dd72Test
https://doi.org/10.1126/science.abl4546Test

المؤلفون: Pratibha Kumari, Peter Z. Qin, Xiongping Chen, Kesavan Babu, Venkatesan Kathiresan, Rakhi Rajan, Sydney Newsom, Jin Liu, Hari Priya Parameshwaran

المصدر: Biochemistry. 60:3783-3800

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Streptococcus pyogenes, Gene Expression, Molecular Dynamics Simulation, Crystallography, X-Ray, Cleavage (embryo), Biochemistry, DNA sequencing, Substrate Specificity, chemistry.chemical_compound, Protein Domains, CRISPR-Associated Protein 9, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Protein Interaction Domains and Motifs, Guide RNA, DNA Cleavage, Nuclease, Binding Sites, biology, Chemistry, Cas9, RNA, DNA, Kinetics, Mutation, Biophysics, biology.protein, Thermodynamics, Protein Conformation, beta-Strand, CRISPR-Cas Systems, Protein Binding, RNA, Guide, Kinetoplastida

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20300d5bb518c29518d846d83533579Test
https://doi.org/10.1021/acs.biochem.1c00354Test

المؤلفون: Yeu Khai Choong, Edem Gavor, R. Manjunatha Kini, Chacko Jobichen, Yu-Keung Mok, J. Sivaraman

المصدر: Protein Sci

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, Proteases, Carboxypeptidases A, Full‐Length Papers, medicine.medical_treatment, Genetic Vectors, Gene Expression, Aedes aegypti, Crystallography, X-Ray, Biochemistry, Substrate Specificity, Species Specificity, Aedes, Catalytic Domain, Escherichia coli, medicine, Animals, Protease Inhibitors, Protein Interaction Domains and Motifs, Amino Acid Sequence, cardiovascular diseases, Cloning, Molecular, Molecular Biology, chemistry.chemical_classification, Protease, Sequence Homology, Amino Acid, biology, Chemistry, fungi, Midgut, biology.organism_classification, Carboxypeptidase, Carboxypeptidase B, Recombinant Proteins, Potato carboxypeptidase inhibitor, Kinetics, surgical procedures, operative, Enzyme, Conventional PCI, biology.protein, Insect Proteins, Cattle, Protein Conformation, beta-Strand, Sequence Alignment, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d09c2c2b8f33d6fc68985426073ee2Test
https://doi.org/10.1002/pro.4212Test

المؤلفون: Irene W. Ng, Min-Guan Lin, Azhar F Kabli, Bo-Wei Chen, Daniela Barillà, Chwan-Deng Hsiao, Yo-You Shen, Che-Ting Wu, Cheng-Yi Yen, Yuh-Ju Sun, Chen-Hao Chen, Nicholas Read

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Models, Molecular, AcademicSubjects/SCI00010, Chromosomes, Archaeal, Protein Conformation, ATPase, Archaeal Proteins, ved/biology.organism_classification_rank.species, Crystallography, X-Ray, Genome, Chromosome segregation, chemistry.chemical_compound, Adenosine Triphosphate, Structural Biology, Chromosome Segregation, Genetics, Adenosine Triphosphatases, biology, ved/biology, Sulfolobus solfataricus, Chromosome, biology.organism_classification, Chromatin, Cell biology, Adenosine Diphosphate, DNA-Binding Proteins, Microscopy, Electron, Segrosome, DNA, Archaeal, chemistry, Multiprotein Complexes, Mutation, biology.protein, Nucleic Acid Conformation, DNA, Archaea, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09407c6a25a8cde9365cdebe5e16159Test
http://europepmc.org/articles/PMC8682754Test