نتائج البحث - "Blake T. Aftab"

1

Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies

المؤلفون: Manher A. Joshi, Michael P. Pender, Lawrence Steinman, Blake T. Aftab, Tap Maniar, Rajiv Khanna, Gavin Giovannoni, Hans-Peter Hartung, Ed Croze, Amit Bar-Or

المصدر: Trends in Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Epstein-Barr Virus Infections, Herpesvirus 4, Human, Disease, medicine.disease_cause, multiple sclerosis, Insert (molecular biology), Virus, Article, Epstein–Barr virus, 03 medical and health sciences, Text mining, 0302 clinical medicine, Immune system, ocrelizumab, Animals, Humans, Medicine, Molecular Biology, cell-based therapies, immune evasion, T-cell apoptosis, B-Lymphocytes, Microglia, biology, business.industry, Multiple sclerosis, Correction, medicine.disease, vaccination, Molecular medicine, Vaccination, medicine.anatomical_structure, 030104 developmental biology, Immunology, Cancer research, biology.protein, Molecular Medicine, Ocrelizumab, Immunotherapy, Antibody, business, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e5b0d38d9681dd831b9b7c7cb19fb0Test
http://europepmc.org/articles/PMC7106557Test

2

98 ATA3271: an armored, next-generation off-the-shelf, allogeneic, mesothelin-CAR T cell therapy for solid tumors

المؤلفون: P. Foubert, Xianhui Chen, Jiangyue Liu, Jason Karlen, Blake T. Aftab, Alfonso Brito, Yannick Bulliard, Tiffany Jheng, Janani Krishnamurthy

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

مصطلحات موضوعية: biology, business.industry, T cell, T-cell receptor, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Chimeric antigen receptor, CD19, Transplantation, Immune system, medicine.anatomical_structure, medicine, biology.protein, Cancer research, Rituximab, Mesothelin, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1d7a475e4348aa5ad3edf87660280fTest
https://doaj.org/article/c227a2556f964e5fbdeed687d179a83eTest

3

ATA3219: A Potent Next-Generation Allogeneic Off-the-Shelf CD19 CAR-T Therapy without the Need for Gene Editing

المؤلفون: Tassja J. Spindler, Yannick Bulliard, Blake T. Aftab, Edward Hwang, Alfonso Brito, Christina Pham

المصدر: Transplantation and Cellular Therapy. 27:S186-S187

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4f2c0f3e1275204b7b7a63b5b982f9f4Test
https://doi.org/10.1016/s2666-6367Test(21)00229-3

4

ATA3219: A Potent Next-Generation Allogeneic Off-the-Shelf CD19-CAR T Therapy without the Need for Gene-Editing

المؤلفون: Tassja J. Spindler, Alfonso Brito, Yannick Bulliard, Christina Pham, Edward Hwang, Blake T. Aftab

المصدر: Blood. 136:9-9

مصطلحات موضوعية: biology, business.industry, T cell, Immunology, T-cell receptor, Context (language use), Cell Biology, Hematology, medicine.disease, Biochemistry, CD19, Chimeric antigen receptor, Cytokine release syndrome, medicine.anatomical_structure, Antigen, medicine, biology.protein, Cancer research, business, B cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d61c56b97c6b823866c7c909b022dc97Test
https://doi.org/10.1182/blood-2020-141262Test

5

Abstract A2-57: Identification of genetic vulnerabilities within the proteostasis network of multiple myeloma

المؤلفون: Diego Acosta-Alvear, Jonathan S. Weissman, Jason E. Gestwicki, Martin Kampmann, Min Y. Cho, Xiaokai Li, Marc A. Shuman, Blake T. Aftab, Peter Walter

المصدر: Cancer Research. 75:A2-57

مصطلحات موضوعية: Cancer Research, biology, Bortezomib, Synthetic lethality, Bioinformatics, medicine.disease, Small hairpin RNA, Proteostasis, Oncology, Ubiquitin, Proteasome, Cancer research, medicine, biology.protein, Unfolded protein response, Multiple myeloma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0b2e39857c1a4121c856f3fdbacaceb1Test
https://doi.org/10.1158/1538-7445.transcagen-a2-57Test

6

Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer

المؤلفون: Jennifer N. Rauch, Bryan M. Dunyak, Byron Hann, Peter Walter, Martin Kampmann, Megan Murnane, Min Cho, Xiaokai Li, Teresa A. Colvin, Jason E. Gestwicki, Diego Acosta-Alvear, Blake T. Aftab, Jonathan S. Weissman, Michael Y. Sherman

المصدر: Molecular cancer therapeutics, vol 14, iss 3

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Oncology and Carcinogenesis, Allosteric regulation, Antineoplastic Agents, Pharmacology, BAG3, Article, Cell Line, Protein–protein interaction, Mice, Cell Line, Tumor, Proliferating Cell Nuclear Antigen, 2.1 Biological and endogenous factors, Animals, Humans, HSP70 Heat-Shock Proteins, Protein Interaction Domains and Motifs, Oncology & Carcinogenesis, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, Cell Proliferation, Regulation of gene expression, Neoplastic, Tumor, biology, Effector, Forkhead Box Protein M1, Signal Transducing, Adaptor Proteins, Signal transducing adaptor protein, Forkhead Transcription Factors, Pharmacology and Pharmaceutical Sciences, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Oncology, Hela Cells, Chaperone (protein), MCF-7 Cells, Cancer research, biology.protein, FOXM1, Apoptosis Regulatory Proteins, HT29 Cells, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b22505bee1d46a3729d48f13aa063Test
https://doi.org/10.1158/1535-7163.mct-14-0650Test

7

The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma

المصدر: Molecular cancer therapeutics. 16(11)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Proteasome Endopeptidase Complex, Indoles, Apoptosis, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, P97 Inhibitor CB-5083, medicine, Animals, Humans, Nuclear protein, Multiple myeloma, Cell Proliferation, Adenosine Triphosphatases, Cell growth, Nuclear Respiratory Factor 1, Nuclear Proteins, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Pyrimidines, Oncology, Proteasome, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, biology.protein, Proteasome inhibitor, Unfolded Protein Response, Multiple Myeloma, Proteasome Inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdabd665906a2c466a4f478c5ace23bbTest
https://pubmed.ncbi.nlm.nih.gov/28878026Test

8

Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells

المؤلفون: Peter Walter, Xiaobo Wu, Daniel W. Sherbenou, Bin Liu, Blake T. Aftab, Diego Acosta-Alvear, Thomas G. Martin, Aaron C Logan, Yang Su, Byron Hann, Marc A. Shuman, John P. Atkinson, Jeffrey L. Wolf, Arun P. Wiita, Christopher R. Behrens

المصدر: The Journal of clinical investigation, vol 126, iss 12

مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Antibodies, Neoplasm, viruses, Cell, Gene Dosage, Medical and Health Sciences, Mice, Monoclonal, Multiple myeloma, Cancer, Tumor, biology, Antibodies, Monoclonal, General Medicine, Hematology, female genital diseases and pregnancy complications, 3. Good health, medicine.anatomical_structure, 5.1 Pharmaceuticals, Chromosomes, Human, Pair 1, Pair 1, Antibody, Development of treatments and therapeutic interventions, Multiple Myeloma, Human, Biotechnology, Research Article, Antibody-drug conjugate, medicine.drug_class, Immunology, Monoclonal antibody, Chromosomes, Antibodies, Cell Line, Membrane Cofactor Protein, 03 medical and health sciences, Rare Diseases, Clinical Research, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Innate immune system, business.industry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Neoplasm, Bone marrow, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4493ea8c812dbe33beb060ad3da7b1b3Test
https://europepmc.org/articles/PMC5127683Test/

9

Abstract 2310: Functional demonstration of CD19 chimeric antigen receptor (CAR) engineered Epstein-Barr virus (EBV) specific T cells: An off-the-shelf, allogeneic CAR T-cell immunotherapy platform

المؤلفون: Blake T. Aftab, Daniel Munson, Christina Pham, Michelle Min Wu, Rhine R. Shen

المصدر: Cancer Research. 79:2310-2310

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::638bdc1a667f2bea8716e65bf1b3ed78Test
https://doi.org/10.1158/1538-7445.am2019-2310Test

10

CD19 chimeric antigen receptor (CAR) engineered epstein-barr virus (EBV) specific T cells – an off-the-shelf, allogeneic CAR T-cell immunotherapy platform

المؤلفون: D.J. Munson, C.D. Pham, R.R. Shen, Blake T. Aftab, M. Wu

المصدر: Cytotherapy. 21:S11

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6b06320678f2aa5d12dc123aa2b8843bTest
https://doi.org/10.1016/j.jcyt.2019.03.569Test

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