المؤلفون: Tatiana Gamez, Carlos Vargas, Christian Rolfo, Pilar Archila, Luis Corrales, Oscar Arrieta, Claudio Martin, Jorge Otero, C. Sotelo, Hernán Carranza, Juan Esteban Garcia-Robledo, D. Mayorga, Luisa Ricaurte, Camila Ordóñez-Reyes, Lucia Zatarain Barron, L. Rojas, Rafael Rosell, Luis Mas, Alejandro Ruiz-Patiño, Maritza Bermudez, July Rodriguez, J. Ávila, Andrés F. Cardona, Gonzalo Recondo, Feliciano Barrón

المساهمون: Cardona, Andrés Felipe [0000-0003-3525-4126], Garcia-Robledo, Juan Esteban [0000-0003-2912-152X]

المصدر: Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Lung Neoplasms, Bevacizumab, First line, Pacientes con receptor del factor de crecimiento epidérmico (EGFR), Patients with epidermal growth factor receptor (EGFR), Young Adult, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, harboring BIM deletion polymorphism (BIM deletion), Carcinoma, Non-Small-Cell Lung, medicine, Humans, mutated non–small-cell lung cancer (NSCLC), Epidermal growth factor receptor, Lung cancer, Aged, Neoplasm Staging, Retrospective Studies, EGFR inhibitors, Polimorfismo de eliminación BIM (eliminación BIM), Polymorphism, Genetic, Bcl-2-Like Protein 11, biology, business.industry, Kinase, Middle Aged, medicine.disease, respiratory tract diseases, ErbB Receptors, Drug Combinations, 030104 developmental biology, Oncology, Apoptosis, Egfr mutation, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Female, business, Gene Deletion, Cáncer de pulmón de células no pequeñas (CPCNP) mutado, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f368f60a7559c0ff0c3e0f742a7de86eTest
https://doi.org/10.1200/po.20.00404Test

المؤلفون: Wenyi Wei, Songqing Fan, Guoqing Qian, Karin A. Vallega, Qiming Wang, Yunfu Deng, Zhen Chen, Suresh S. Ramalingam, Jianping Guo, Taofeek K. Owonikoko, Changjiang Hu, Shi-Yong Sun

المصدر: Mol Cancer Res

مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Ubiquitin-Protein Ligases, Mice, Nude, Apoptosis, B7-H1 Antigen, Article, Cell Line, Glycogen Synthase Kinase 3, Mice, Ubiquitin, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, PD-L1, Animals, Humans, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, EGFR inhibitors, Acrylamides, Gene knockdown, Aniline Compounds, biology, Chemistry, Ubiquitin ligase, ErbB Receptors, Gene Expression Regulation, Neoplastic, HEK293 Cells, Oncology, Mutation, Cancer cell, biology.protein, Cancer research, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49618826ca7fd0d978235270c398bde2Test
https://doi.org/10.1158/1541-7786.mcr-21-0147Test

المؤلفون: Arjan Gower, Edward B. Garon

المصدر: Nature

مصطلحات موضوعية: Lung Neoplasms, biology, business.industry, General Medicine, Article, respiratory tract diseases, ErbB Receptors, Targeted therapies, Egfr mutation, Carcinoma, Non-Small-Cell Lung, Mutation, Cancer research, biology.protein, Medicine, Humans, Non small cell, Epidermal growth factor receptor, business, Protein Kinase Inhibitors, Non-small-cell lung cancer, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cfcb72bd1a33c72e3ba4014c9c4703Test
https://pubmed.ncbi.nlm.nih.gov/34526717Test

المؤلفون: Alexandra E. Rader, Carlota Rubio-Perez, Maxim V. Frolov, Mary Pasquinelli, Majd M. Ariss, Ryan D. Conrardy, Abul B. M. M. K. Islam, Alexa M. Gajda, Lawrence Eric Feldman, Cammille C. Go, Stefan J. Green, Alexandre Ferro Aissa, Elizaveta V. Benevolenskaya, Nuria Lopez-Bigas, Klara Valyi-Nagy

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-25 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Epithelial-Mesenchymal Transition, Cancer therapy, Cell Survival, Science, General Physics and Astronomy, Antineoplastic Agents, Drug resistance, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Receptor tyrosine kinase, Gene regulatory networks, 03 medical and health sciences, 0302 clinical medicine, Drug tolerance, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Cancer models, Protein Kinase Inhibitors, EGFR inhibitors, Multidisciplinary, Crizotinib, Drug discovery, Receptor Protein-Tyrosine Kinases, Drug Tolerance, U937 Cells, General Chemistry, respiratory tract diseases, ErbB Receptors, Gene Expression Regulation, Neoplastic, Drug Combinations, Cholesterol, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Heterografts, Vesicle-mediated transport, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5567cf379b66251833dd58cf46aa6c95Test
https://doaj.org/article/07bdc3f7e13d4e018edb5f1887d9c903Test

المؤلفون: Julie K.-L. Sinclair, Alanna Schepartz, Deepto Mozumdar, Kim Quach, Wesley E. Robertson

المصدر: Biochemistry. 60:500-512

مصطلحات موضوعية: Coiled coil, Mutation, biology, Chemistry, Kinase, Activator (genetics), Cell Membrane, Allosteric regulation, medicine.disease_cause, Biochemistry, Cell biology, ErbB Receptors, Structure-Activity Relationship, T790M, Cell Line, Tumor, medicine, biology.protein, Humans, Amino Acid Sequence, Epidermal growth factor receptor, Protein Kinase Inhibitors, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b121cadeb61cffd1c519f1feb08501cTest
https://doi.org/10.1021/acs.biochem.0c00978Test

المؤلفون: Karin A. Vallega, Danlei Yu, Shi-Yong Sun, Wen Zhao

المصدر: Lung Cancer: Targets and Therapy

مصطلحات موضوعية: Mutation, EGFR inhibitors, biology, business.industry, acquired resistance, Erk signaling, Review, medicine.disease, medicine.disease_cause, respiratory tract diseases, lung cancer, T790M, Acquired resistance, Oncology, osimertinib, Cancer research, medicine, biology.protein, Osimertinib, Epidermal growth factor receptor, Lung cancer, business, MEK/ERK

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65be55b4641a36bf48d813809a84c83Test
https://doi.org/10.2147/lctt.s293902Test

المؤلفون: Myung-Ju Ahn, Hongsik Kim, Se-Hoon Lee, Hyun Ae Jung, Jin Seok Ahn, Jong-Mu Sun, Keunchil Park

المصدر: Transl Lung Cancer Res

مصطلحات موضوعية: Oncology, Mutation, medicine.medical_specialty, biology, business.industry, non-small cell lung cancer (NSCLC), medicine.disease, medicine.disease_cause, respiratory tract diseases, 03 medical and health sciences, T790M, 0302 clinical medicine, Acquired resistance, 030220 oncology & carcinogenesis, Internal medicine, medicine, biology.protein, Original Article, 030212 general & internal medicine, Non small cell, Epidermal growth factor receptor, business, Lung cancer, EGFR inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2864524eb44220f78133ba33ee0393Test
https://doi.org/10.21037/tlcr-20-1128Test

المؤلفون: Juliet Williams, Jeffrey A. Engelman, Guizhi Yang, Matthew J. Meyer, Huai Xiang Hao, William D. Hastings, Chen Liu, Tinya Abrams, Silvia Goldoni, Hui Gao, Giordano Caponigro, Peter S. Hammerman, Hongyun Wang, Colleen Kowal, Scott Delach, Alice Loo, Hengyu Lu, Susan Moody, Matthew J. LaMarche, Ye Wang, Karrie Wong, Morvarid Mohseni, Xiamei Zhang

المصدر: Clinical Cancer Research. 27:342-354

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, 0301 basic medicine, MAPK/ERK pathway, Cancer Research, Programmed Cell Death 1 Receptor, Allosteric regulation, Protein Tyrosine Phosphatase, Non-Receptor Type 11, medicine.disease_cause, Receptor tyrosine kinase, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Cell Line, Tumor, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, medicine, Animals, Humans, Immune Checkpoint Inhibitors, Protein Kinase Inhibitors, EGFR inhibitors, Tumor microenvironment, biology, Chemistry, Cyclin-Dependent Kinase 4, Cancer, Drug Synergism, Cyclin-Dependent Kinase 6, medicine.disease, Xenograft Model Antitumor Assays, ErbB Receptors, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer cell, biology.protein, Cancer research, Female, KRAS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3c3f6b2f214726db8bd9a82f04ec4Test
https://doi.org/10.1158/1078-0432.ccr-20-2718Test

المؤلفون: Iqrar Ahmad, Arabinda Ghosh, Sanjay J. Surana, Harun M. Patel, Matin Shaikh

المصدر: Journal of Biomolecular Structure and Dynamics. 40:3046-3059

مصطلحات موضوعية: Lung Neoplasms, non-small cell lung cancer (NSCLC), Mitogen-Activated Protein Kinase 14, Structural Biology, Carcinoma, Non-Small-Cell Lung, Fourth generation, medicine, Humans, Point Mutation, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Molecular Biology, EGFR inhibitors, Acrylamides, Aniline Compounds, integumentary system, biology, Point mutation, General Medicine, medicine.disease, respiratory tract diseases, ErbB Receptors, Drug Resistance, Neoplasm, Egfr mutation, Mitogen-activated protein kinase, Mutation, biology.protein, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f31142039475ffc50a19319c4875a2Test
https://doi.org/10.1080/07391102.2020.1844801Test

المؤلفون: Rama Suresh, Saiama N. Waqar, Haeseong Park, Benjamin R. Tan, Nikolaos A. Trikalinos, Sarah Larson, Kerry J. Williams, Daniel Morgensztern, A. Craig Lockhart, Andrea Wang-Gillam, Jingqin Luo, Ramaswamy Govindan, Brian A. Van Tine

المصدر: Cancer Chemother Pharmacol

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Toxicology, Article, Cohort Studies, Erlotinib Hydrochloride, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Mucositis, Humans, Pharmacology (medical), Epidermal growth factor receptor, Aged, EGFR inhibitors, Aged, 80 and over, Sirolimus, Pharmacology, Dose-Response Relationship, Drug, biology, business.industry, Middle Aged, medicine.disease, Rash, Temsirolimus, ErbB Receptors, Regimen, Treatment Outcome, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Disease Progression, biology.protein, Female, Erlotinib, Phosphatidylinositol 3-Kinase, medicine.symptom, business, Progressive disease, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883969f26c2a1384c7935fe7c7e39601Test
https://doi.org/10.1007/s00280-020-04183-0Test