المؤلفون: Ting Lan Chiu, Young Kyung Bae, Craig M. Flory, Yelena V. Grinkova, Ameeta Kelekar, Stephen G. Sligar, M. Gerard O'Sullivan, Adela Galván, Irina F. Sevrioukova, Kalpna Gupta, Beverly Norris, Ian A. Blair, Elizabeth A. Ambrose, Fernando Luna, Ilia G. Denisov, John D. Lipscomb, Eric A. Hanse, Haitao Chu, Daniel S. Swedien, Robert J. Schumacher, William M. Atkins, Rebecca A. D. Cuellar, Gunda I. Georg, Julia Wulfkuhle, Zhijun Guo, Rosa I. Gallagher, Thomas L. Poulos, Qing Cao, Vanessa Wankhede Langenfeld, Xia Zhang, John R. Falck, Juan Alvarez, Emanuel F. Petricoin, Dafydd G. Thomas, Jorge H. Capdevila, David Potter, Justin D. Stamschror

المصدر: Cell Chemical Biology. 24:1259-1275.e6

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Cell, Clinical Biochemistry, Biguanides, AMP-Activated Protein Kinases, Mitochondrion, Pharmacology, Biochemistry, Mice, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, Cytochrome P-450 CYP3A, Heme, Membrane Potential, Mitochondrial, biology, Biguanide, Mitochondria, Gene Expression Regulation, Neoplastic, Protein Transport, medicine.anatomical_structure, MCF-7 Cells, Molecular Medicine, Female, Epoxygenase, Heme binding, medicine.drug_class, Cell Respiration, Chemical biology, Breast Neoplasms, Epoxyeicosatrienoic acid, Article, 03 medical and health sciences, medicine, Animals, Humans, Gene Silencing, Molecular Biology, CYP3A4, Estrogen Receptor alpha, Cytochrome P450, Monooxygenase, 030104 developmental biology, chemistry, Cancer cell, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609abd584fa3973a5ec9c305d29ee4ddTest
https://doi.org/10.1016/j.chembiol.2017.08.009Test

المؤلفون: Yan Wu, Yan Tao, Jianrong Sang, Lu Jiang, Ting Lan, Yongchang Chen, Ying Wang

المصدر: Oncology reports. 27(6)

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, MAP Kinase Signaling System, Apoptosis, Breast Neoplasms, MAP Kinase Kinase 7, Cyclic GMP-Dependent Protein Kinase Type II, Cell Line, Tumor, Cyclic GMP-Dependent Protein Kinases, Humans, Phosphorylation, Protein kinase A, Cyclic GMP, GRB2 Adaptor Protein, biology, Oncogene, Epidermal Growth Factor, Kinase, JNK Mitogen-Activated Protein Kinases, General Medicine, Thionucleotides, Molecular biology, ErbB Receptors, Oncology, Cancer cell, biology.protein, ras Proteins, Female, GRB2, Signal transduction, SOS1 Protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fb19c8f6673c4c3b123b841798238aTest
https://pubmed.ncbi.nlm.nih.gov/22427012Test

المؤلفون: Sajiv K. Nair, John T. Henri, Gunda I. Georg, Jack F. Greiner, David VanderVelde, Ting Lan Chiu, Bollu S. Reddy, Oliver E. Hutt, Emily A. Reiff, Elizabeth A. Amin, Richard H. Himes

المصدر: Bioorganicmedicinal chemistry letters. 18(17)

مصطلحات موضوعية: Molecular model, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Breast Neoplasms, Epothilone, Biochemistry, Tubulin, Cell Line, Tumor, Drug Discovery, medicine, Humans, Cytotoxicity, Molecular Biology, biology, Chemistry, Organic Chemistry, Total synthesis, Biological activity, Hydrogen Bonding, In vitro, Tubulin Modulators, MCF-7, Epothilones, biology.protein, Molecular Medicine, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae63626c486d6470f1fbd7a643350d5Test
https://pubmed.ncbi.nlm.nih.gov/18684624Test