يعرض 1 - 10 نتائج من 20 نتيجة بحث عن '"Tuberculosis/genetics"', وقت الاستعلام: 1.01s تنقيح النتائج
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    المساهمون: Instituto de Investigação e Inovação em Saúde, European Research Council, Ministerio de Ciencia, Innovación y Universidades (España), Fundação para a Ciência e a Tecnologia (Portugal), Comas, Iñaki, Chiner-Oms, Álvaro, Instituto de Saúde Pública da Universidade do Porto, Comas, Iñaki [0000-0001-5504-9408], Chiner-Oms, Álvaro [0000-0002-0463-0101]

    المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
    Nature Communications
    Digital.CSIC. Repositorio Institucional del CSIC
    instname

    وصف الملف: application/pdf

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    المصدر: Folkvardsen, D B, Norman, A, Andersen, Å B, Michael Rasmussen, E, Jelsbak, L & Lillebaek, T 2017, ' Genomic Epidemiology of a Major Mycobacterium tuberculosis Outbreak : Retrospective Cohort Study in a Low-Incidence Setting Using Sparse Time-Series Sampling ', Journal of Infectious Diseases, vol. 216, no. 3, pp. 366-374 . https://doi.org/10.1093/infdis/jix298Test
    Folkvardsen, D B, Norman, A, Andersen, Å B, Michael Rasmussen, E, Jelsbak, L & Lillebaek, T 2017, ' Genomic Epidemiology of a Major Mycobacterium tuberculosis Outbreak : Retrospective Cohort Study in a Low-Incidence Setting Using Sparse Time-Series Sampling ', The Journal of Infectious Diseases, vol. 216, no. 3, pp. 366-374 . https://doi.org/10.1093/infdis/jix298Test
    Folkvardsen, D B, Norman, A, Andersen, Å B, Rasmussen, E M, Jelsbak, L & Lillebaek, T 2017, ' Genomic epidemiology of a major Mycobacterium tuberculosis outbreak: Retrospective cohort study in a low incidence setting using sparse time-series sampling ', Journal of Infectious Diseases, vol. 216, no. 3 . https://doi.org/10.1093/infdis/jix298Test

    وصف الملف: application/pdf

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    المصدر: The Cochrane Database of Systematic Reviews

    مصطلحات موضوعية: mesh:Tuberculosis, Pulmonary, Extensively Drug-Resistant Tuberculosis, Antibiotics, mesh:Mycobacterium tuberculosis, mesh:Rifampin, Rifampicin resistance, Drug resistance, 0302 clinical medicine, mesh:Mycobacterium tuberculosis/isolation & purification, mesh:Mycobacterium tuberculosis/genetics, polycyclic compounds, Pharmacology (medical), 030212 general & internal medicine, False Negative Reactions, mesh:Mycobacterium tuberculosis/drug effects, biology, mesh:Polymerase Chain Reaction, 3. Good health, mesh:Rifampin/therapeutic use, mesh:Humans, wf_200, mesh:Adult, Rifampin, medicine.drug, Medicine General & Introductory Medical Sciences, mesh:Sequence Analysis, DNA/methods, Tuberculosis, medicine.drug_class, mesh:Tuberculosis, Pulmonary/drug therapy, Microbial Sensitivity Tests, mesh:Sensitivity and Specificity, Sensitivity and Specificity, mesh:Antibiotics, Antitubercular/therapeutic use, Mycobacterium tuberculosis, 03 medical and health sciences, mesh:Drug Resistance, Bacterial, Pulmonary tuberculosis, mesh:Sequence Analysis, DNA, Drug Resistance, Bacterial, medicine, Humans, False Positive Reactions, Diagnostic Errors, mesh:Antibiotics, Antitubercular, Antibiotics, Antitubercular, Tuberculosis, Pulmonary, business.industry, Extrapulmonary tuberculosis, biology.organism_classification, medicine.disease, bacterial infections and mycoses, Virology, mesh:Tuberculosis, Pulmonary/diagnosis, qv_268, mesh:Polymerase Chain Reaction/methods, business, wf_300, 030217 neurology & neurosurgery, Rifampicin

    وصف الملف: application/pdf

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    المساهمون: University of Zaragoza - Universidad de Zaragoza [Zaragoza], Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Pathogénomique mycobactérienne intégrée - Integrated Mycobacterial Pathogenomics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This work was supported in part by the Juan de la Cierva Programme JCI-2009-03799 from the Spanish Ministry of Science and Innovation (to J.G.-A.), the Centre National de la Recherche Scientifique, the Fondation pour la Recherche Médicale ('Equipe FRM' DEQ20090515399 and DEQ20130326471), the European Union 7th Framework Programme (Contracts NEWTBVAC 241745, MM4TB 260872, and FEDER/POCTEFA/REFBIO EFA237/11), the Spanish Ministry of Economy and Competitiveness (Contracts BIO2011-23555 and FIS12/1970), and the Région Midi-Pyrénées (CPER 2007-2013) for the scientific project and for the ASB3 animal facility., We thank Dr. Geanncarlo Lugo-Villarino and Dr. Stephen V. Gordon for critical reading of the manuscript. We thank the members of the Genotoul platforms TRI and ANEXPLO (Institut de Pharmacologie et de Biologie Structurale) for epifluorescence microscopy imaging and for animal experiments, respectively, and Dr. Marie-Agnès Dillies and Dr. Jean-Yves Coppée from the Transcriptome Platform PF2 at the Institut Pasteur for advice., European Project: 241745,EC:FP7:HEALTH,FP7-HEALTH-2009-single-stage,NEWTBVAC(2010), European Project: 260872,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,MM4TB(2011), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Proceedings of the National Academy of Sciences of the United States of America
    Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
    Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (31), pp.11491-11496. ⟨10.1073/pnas.1406693111⟩
    Zaguán. Repositorio Digital de la Universidad de Zaragoza
    instname

    وصف الملف: application/pdf

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    المصدر: Walter, ND; Dolganov, GM; Garcia, BJ; Worodria, W; Andama, A; Musisi, E; et al.(2015). Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human Tuberculosis. Journal of Infectious Diseases, 212(6), 990-998. doi: 10.1093/infdis/jiv149. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1g70p2j2Test
    The Journal of infectious diseases, vol 212, iss 6

    وصف الملف: application/pdf

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    المساهمون: Departamento de Microbiología, Medicina Preventiva y Salud Publica [Zaragoza], Facultad de Medicina [Zaragoza], University of Zaragoza - Universidad de Zaragoza [Zaragoza]-University of Zaragoza - Universidad de Zaragoza [Zaragoza], Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Hospital Universitario Miguel Servet, Pathogénomique mycobactérienne intégrée, Institut Pasteur [Paris] (IP), This work was supported by the European Community's Framework Programme 7 grants NEWTBVAC 241745 and MM4TB 260872, the Spanish Ministry of Economy and Competitiveness grants BIO2011-23555 and FIS12/1970, the Fondation pour la Recherche Médicale FRM no. DEQ20130326471, and the Pyrenees biomedical network Refbio grant SecRegulTBC. Jesús Gonzalo-Asensio was supported by the Juan de la Cierva Programme (JCI-2009-03799) from the Spanish Ministry of Science and Innovation. Luis Solans was supported by grant BES-2009-013037., We thank Marie-Agnès Dillies and Jean-Yves Coppée from the Transcriptome Platform PF2 at the Institut Pasteur for advice and Ida Rosenkrands from Statens Serum Institute for kindly providing the polyclonal anti-SigA antibodies, and we also gratefully acknowledge Alberto Cebollada for help with the sequence analysis of M. tuberculosis strains., European Project: 241745,EC:FP7:HEALTH,FP7-HEALTH-2009-single-stage,NEWTBVAC(2010), European Project: 260872,EC:FP7:HEALTH,FP7-HEALTH-2010-single-stage,MM4TB(2011), Institut Pasteur [Paris]

    المصدر: Infection and Immunity
    Infection and Immunity, 2014, 82 (8), pp.3446-3456. ⟨10.1128/iai.01824-14⟩
    Infection and Immunity, American Society for Microbiology, 2014, 82 (8), pp.3446-3456. ⟨10.1128/iai.01824-14⟩

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    المساهمون: Department of Bio-engineering Sciences, Structural Biology Brussels, Dynamique des interactions membranaires normales et pathologiques (DIMNP), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Structural Biology Brussels (SBB), Vrije Universiteit Brussel (VUB), This work was supported by grants from the French National Research Agency (ANR-09-MIEN-004) to V.M. and L.K. The authors wish to thank the Région Languedoc-Roussillon and the University of Montpellier 1 to J.L., The authors wish to thank I. Zanella-Cléon, Frédéric Delolme and Aurélie Cornut (IBCP, Lyon, France) for their excellent mass spectrometry expertise and technical assistance., ANR-09-MIEN-0004,CHIP_MYCOPHOS,Identification de régulons sous contrôle de régulateurs phosphorylés et leur rôle dans l'adaptation des mycobacteries dans leur environnement : une approche via 'ChIP-on-chip' chez Mycobacterium tuberculosis(2009), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université Montpellier 1 (UM1)

    المصدر: Biochemical and Biophysical Research Communications
    Biochemical and Biophysical Research Communications, 2014, 446 (4), pp.1132-1138. ⟨10.1016/j.bbrc.2014.03.074⟩
    Biochemical and Biophysical Research Communications, Elsevier, 2014, 446 (4), pp.1132-1138. ⟨10.1016/j.bbrc.2014.03.074⟩

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    المساهمون: Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), National Institute of Hygiene and Epidemiology [Hanoi, Vietnam] (NIHE), Réseau International des Instituts Pasteur (RIIP), Hanoi University of Science and Technology (HUST), Laboratoire Mixte International Drug Resistance in Southeast Asia (LMI DRISA), Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Oxford University Clinical Research Unit [Ho Chi Minh City] (OUCRU)-Fondation Mérieux-University of sciences and technologies of hanoi (USTH)-Center of Infectiology Lao-Christophe Mérieux [Vientiane] (CILM), National Lung Hospital [Hanoi, Viet Nam], Pham Ngoc Thach Hospital, Vietnam Military Medical University, Du gène à l'écosystème (MIVEGEC-GeneSys), Pathogènes, Environnement, Santé Humaine (EPATH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), This work was supported by grants of the following projects: the PHC Lotus, the GDRI ID-BIO, the KC.10.15/06-10, the JEAI MySA, the LMI DRISA, and an ADB BIO3 USTH project. We would like to thank the Viet Nam National Tuberculosis Programme, National Lung Hospital, Pham Ngoc Thach Hospital and Hue Central Hospital for M. tuberculosis sampling. We also thank NIHE, IRD, CNRS and USTH for their support. Nguyen Quang Huy was supported by the project 911 scholarship from the Vietnamese Government., We are grateful to Elisabetta Andermarcher for editing the English., Fondation Mérieux-Center of Infectiology Lao-Christophe Mérieux [Vientiane] (CILM)-Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-University of sciences and technologies of hanoi (USTH)-Oxford University Clinical Research Unit [Ho Chi Minh City] (OUCRU)

    المصدر: Infection, Genetics and Evolution
    Infection, Genetics and Evolution, Elsevier, 2017, 50, pp.55-61. ⟨10.1016/j.meegid.2017.02.012⟩

    مصطلحات موضوعية: 0301 basic medicine, MESH: Pentosyltransferases/genetics, Extensively Drug-Resistant Tuberculosis, Antitubercular Agents, Gene Expression, Drug resistance, MESH: Streptomycin/pharmacology, MIRU-VNTR, MESH: Mycobacterium tuberculosis/genetics, MESH: Genetic Fitness, MESH: Drug Resistance, Multiple, Bacterial/genetics, Drug Resistance, Multiple, Bacterial, Genotype, Second line drugs, MESH: Genetic Variation, MESH: Mycobacterium tuberculosis/isolation & purification, MESH: Ethambutol/pharmacology, MESH: Extensively Drug-Resistant Tuberculosis/microbiology, Spoligotyping, Genetics, education.field_of_study, MESH: Rifampin/pharmacology, Isoniazid, DNA-Directed RNA Polymerases, Catalase, 3. Good health, Bacterial Typing Techniques, Drug resistance-associated mutations, MESH: Antitubercular Agents/pharmacology, Infectious Diseases, Vietnam, DNA Gyrase, MESH: DNA-Directed RNA Polymerases/genetics, Streptomycin, Rifampin, Oxidoreductases, Ethambutol, medicine.drug, Microbiology (medical), Ribosomal Proteins, MESH: Oxidoreductases/genetics, MESH: Gene Expression, Tuberculosis, 030106 microbiology, Population, Biology, MESH: Bacterial Proteins/genetics, Microbiology, MESH: Bacterial Typing Techniques, MESH: DNA Gyrase/genetics, Mycobacterium tuberculosis, 03 medical and health sciences, Bacterial Proteins, medicine, MESH: Catalase/genetics, Humans, Pentosyltransferases, education, Molecular Biology, Ecology, Evolution, Behavior and Systematics, MESH: Isoniazid/pharmacology, First line drugs, MESH: Humans, Genetic Variation, biology.organism_classification, medicine.disease, Extensively drug resistance, MESH: Ribosomal Proteins/genetics, MESH: Mycobacterium tuberculosis/drug effects, Mutation, MESH: Mutation, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Genetic Fitness, MESH: Vietnam, Drug susceptibility testing, Rifampicin

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    المساهمون: Pathogénomique mycobactérienne intégrée, Institut Pasteur [Paris] (IP), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie Cellulaire des Lymphocytes - Lymphocyte Cell Biology, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Génomique (Plate-Forme) - Genomics Platform, Victorian Life Sciences Computation Initiative, University of Melbourne, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), The Peter Doherty Institute for Infection and Immunity [Melbourne], University of Melbourne-The Royal Melbourne Hospital, This study was in part supported by the European Community’s Grants 260872 and 643381, European Union - European Federation of Pharmaceutical Industries and Associations Innovative Medicines Initiative Grant 115337, Agence National de Recherche Grant ANR-14-JAMR-001-02, and Fondation pour la Recherche Médicale FRM Grant DEQ20130326471. R.B. is a member of the LabEx consortium ANR-10-LABX-62-IBEID at the Institut Pasteur. E.C.B. was supported by a stipend from the Pasteur–Paris University International PhD program and the Institut Carnot Pasteur Maladies Infectieuses., We thank William R. Jacobs for providing M. smegmatis mc2874 and M. tuberculosis ΔRD1 strains, Denis A. Mitchison for providing M. tuberculosis strain 79112, and Dick van Soolingen for M. tuberculosis strain Tb36. We thank Louis Jones for setup of the CanettiiList server. Whole-genome sequencing was performed at the Institut Pasteur Genomics Platform, member of the 'France Génomique' consortium (ANR10-INBS-09-08). We thank the students of the Institut Pasteur genome analysis course for contributing one M. smegmatis clone for further analysis., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris], Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur [Paris], Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), The Royal Melbourne Hospital-University of Melbourne

    المصدر: Proceedings of the National Academy of Sciences of the United States of America
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (35), pp.9876-9881. ⟨10.1073/pnas.1604921113⟩
    Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (35), pp.9876-9881. ⟨10.1073/pnas.1604921113⟩