المؤلفون: Post, Yorick, Puschhof, Jens, Beumer, Joep, Kerkkamp, Harald M, de Bakker, Merijn A G, Slagboom, Julien, de Barbanson, Buys, Wevers, Nienke R, Spijkers, Xandor M, Olivier, Thomas, Kazandjian, Taline D, Ainsworth, Stuart, Iglesias, Carmen Lopez, van de Wetering, Willine J, Heinz, Maria C, van Ineveld, Ravian L, van Kleef, Regina G D M, Begthel, Harry, Korving, Jeroen, Bar-Ephraim, Yotam E, Getreuer, Walter, Rios, Anne C, Westerink, Remco H S, Snippert, Hugo J G, van Oudenaarden, Alexander, Peters, Peter J, Vonk, Freek J, Kool, Jeroen, Richardson, Michael K, Casewell, Nicholas R, Clevers, Hans, Landdegradatie en aardobservatie, One Health Toxicologie, dIRAS RA-1, Sub Developmental Biology, Dep Farmaceutische wetenschappen, Developmental Biology

المساهمون: Landdegradatie en aardobservatie, One Health Toxicologie, dIRAS RA-1, Sub Developmental Biology, Dep Farmaceutische wetenschappen, Developmental Biology, Faculteit FHML Centraal, Institute of Nanoscopy (IoN), RS: M4I - Nanoscopy, BioAnalytical Chemistry, AIMMS, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Cell, 180(2), 233-247.e21. Cell Press
Post, Y, Puschhof, J, Beumer, J, Kerkkamp, H M, de Bakker, M A G, Slagboom, J, de Barbanson, B, Wevers, N R, Spijkers, X M, Olivier, T, Kazandjian, T D, Ainsworth, S, Iglesias, C L, van de Wetering, W J, Heinz, M C, van Ineveld, R L, van Kleef, R G D M, Begthel, H, Korving, J, Bar-Ephraim, Y E, Getreuer, W, Rios, A C, Westerink, R H S, Snippert, H J G, van Oudenaarden, A, Peters, P J, Vonk, F J, Kool, J, Richardson, M K, Casewell, N R & Clevers, H 2020, ' Snake Venom Gland Organoids ', Cell, vol. 180, no. 2, pp. 233-247.e21 . https://doi.org/10.1016/j.cell.2019.11.038Test
Cell, 180(2), 233. Cell Press
Cell, 180(2), 233-247.e21. Elsevier B.V.
CELL, 180(2), 233-247. CELL PRESS

مصطلحات موضوعية: Cell Culture Techniques, Venom, Stem cell marker, Salivary Glands, Transcriptome, transcriptomics, 0302 clinical medicine, 0303 health sciences, snake, Stem Cells, TERM PRIMARY CULTURE, LGR5, Snakes, knock-in reporter, Cell biology, Organoids, RECEPTORS, Adult Stem Cells, Snake venom, Stem cell, STEM-CELLS, Adult stem cell, wd_410, Snake Venoms, PROTEINS, organoid, qu_475, Coral Snakes, Biology, SECRETORY-CELLS, complex mixtures, General Biochemistry, Genetics and Molecular Biology, Lgr5, 03 medical and health sciences, stem cells, single cell RNA sequencing, Organoid, Animals, SDG 14 - Life Below Water, 030304 developmental biology, Toxins, Biological, venom gland, IDENTIFICATION, Gene Expression Profiling, qu_300, IN-VITRO, NEUROTOXINS, EVOLUTION, qu_550, heterogeneity, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf196fe1a6723ec147a5346143d623e9Test
https://doi.org/10.1016/j.cell.2019.11.038Test

المؤلفون: Welling, Maaike, Chen, Hsu Hsin, Munoz Peralta, Javier, Musheev, Michael U., Kester, Lennart, Junker, Jan Philipp, Mischerikow, Nikolai, Arbab, Mandana, Kuijk, Ewart, Silberstein, Lev, Kharchenko, Peter V., Geens, Mieke, Niehrs, Christof, Van De Velde, Hilde, Van Oudenaarden, Alexander, Heck, Albert J R, Geijsen, Niels, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Sub Biomol.Mass Spect. and Proteomics, Faculty of Veterinary Medicine Research Groups, CSCA TR1

المساهمون: Reproduction and Genetics, Basic (bio-) Medical Sciences, Faculty of Medicine and Pharmacy, Reproductive immunology and implantation, Oral Health, Biomolecular Mass Spectrometry and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Sub Biomol.Mass Spect. and Proteomics, Faculty of Veterinary Medicine Research Groups, CSCA TR1, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: EMBO Reports, 16(7), 791-802. Nature Publishing Group
EMBO Reports, 16(7), 791. Nature Publishing Group

مصطلحات موضوعية: Cellular differentiation, Biochemistry, DAZL, Mice, DNA hydroxymethylation, PRIMORDIAL GERM-CELLS, Induced pluripotent stem cell, Non-U.S. Gov't, IN-VIVO, Genetics, Research Support, Non-U.S. Gov't, METHYLATION, Gene Expression Regulation, Developmental, RNA-Binding Proteins, Cell Differentiation, Mouse Embryonic Stem Cells, Cellular Reprogramming, Cell biology, DNA-Binding Proteins, DIFFERENTIATION, DNA methylation, Reprogramming, Germ Layers, DNA Hydroxymethylation, Pluripotent Stem Cells, naïve pluripotency, Biology, Research Support, Cytosine, DNA DEMETHYLATION, SINGLE-CELL, Proto-Oncogene Proteins, 2i conditions, Journal Article, Animals, 5-METHYLCYTOSINE, RNA, Messenger, Molecular Biology, Scientific Reports, naive pluripotency, Dazl, DNA Methylation, Embryonic stem cell, TET1, SELF-RENEWAL, Epiblast, Protein Biosynthesis, Transcriptome, GROUND-STATE PLURIPOTENCY

وصف الملف: image/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b4e489c1886d47733e8e648ef56d56Test
https://hdl.handle.net/20.500.14017/74eec24e-83ae-4ce5-9d49-0499c658bee3Test

المؤلفون: Fang, Miaoqing, Xie, Huangming, Dougan, Stephanie K., Ploegh, Hidde, van Oudenaarden, Alexander

المصدر: PLoS Biology; Jul2013, Vol. 11 Issue 7, p1-13, 13p

مصطلحات موضوعية: CELLULAR immunity, TRANSCRIPTION factors, CYTOKINES, GENE expression, GENETIC regulation

المؤلفون: Samadani, Azadeh, Mettetal, Jerome, Van Oudenaarden, Alexander

المصدر: Proceedings of the National Academy of Sciences of the United States of America; 8/1/2006, Vol. 103 Issue 31, p11549-11554, 6p, 21 Graphs

مصطلحات موضوعية: CELLS, DICTYOSTELIUM, CYTOLOGY, BIOPHYSICS, BIOLOGY, PULSE (Heart beat)

المؤلفون: Ozbudak, Ertugrul M., Becskei, Attila, van Oudenaarden, Alexander avano@mit.edu

المصدر: Developmental Cell. Oct2005, Vol. 9 Issue 4, p565-571. 7p.

مصطلحات موضوعية: *CELLS, *BIOLOGY, *CYTOLOGY, *GENETICS, *YEAST

المؤلفون: Naomi Moris, Julia Schröder, Sabitri Ghimire, Alexander van Oudenaarden, Susanne C. van den Brink, Alfonso Martinez Arias, Tina Balayo, Kerim Anlas, Anna Alemany

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Moris, Naomi [0000-0003-1910-5454], van den Brink, Susanne C [0000-0003-3683-7737], Alemany, Anna [0000-0002-0795-0290], van Oudenaarden, Alexander [0000-0002-9442-3551], Martinez Arias, Alfonso [0000-0002-1781-564X], Apollo - University of Cambridge Repository

المصدر: Nature, 582(7812), 410-415. Nature Publishing Group
Nature

مصطلحات موضوعية: Human Embryonic Stem Cells/cytology, Human Embryonic Stem Cells, ved/biology.organism_classification_rank.species, Gastrula/cytology, Germ layer, Biology, In Vitro Techniques, Somites/cytology, 03 medical and health sciences, 0302 clinical medicine, Somitogenesis, Humans, Developmental, Model organism, Body Patterning, 030304 developmental biology, 0303 health sciences, Multidisciplinary, ved/biology, Gene Expression Regulation, Developmental, Embryo, Gastrula, Embryonic stem cell, Body Patterning/genetics, Cell biology, Organoids, Gastrulation, Multicellular organism, Body plan, Somites, Gene Expression Regulation, Organoids/cytology, Transcriptome, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e426d3042fc0f6f8722ca81b317059Test
https://doi.org/10.1038/s41586-020-2383-9Test

المؤلفون: Alexander van Oudenaarden, Rita Droste, Christoph Engert, H. Robert Horvitz

المساهمون: Massachusetts Institute of Technology. Computational and Systems Biology Program, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, McGovern Institute for Brain Research at MIT, Engert, Christoph, Droste, Rita, van Oudenaarden, Alexander, Horvitz, Howard Robert, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: PLoS Genetics, Vol 14, Iss 4, p e1007295 (2018)
PLoS Genetics
PLoS
PLoS Genetics, 14(4). Public Library of Science

مصطلحات موضوعية: 0301 basic medicine, RNA, Messenger/genetics, Male, Cancer Research, Transcription, Genetic, Nematoda, Polycomb-Group Proteins, Gene Expression, Spermatocyte, Biochemistry, Histone-Lysine N-Methyltransferase/genetics, Histones, Spermatocytes/metabolism, Spermatocytes, Animal Cells, Gene expression, Caenorhabditis elegans/enzymology, Genetics (clinical), Caenorhabditis elegans, In Situ Hybridization, Fluorescence, In Situ Hybridization, Regulation of gene expression, Chromosome Biology, Nuclear Proteins, Eukaryota, Animal Models, Spermatids, Chromatin, 3. Good health, Cell biology, Major sperm protein, medicine.anatomical_structure, Experimental Organism Systems, Multigene Family, Epigenetics, Cellular Types, Transcription, Research Article, lcsh:QH426-470, DNA transcription, Biology, Research and Analysis Methods, Fluorescence, Chromatin/metabolism, 03 medical and health sciences, Caenorhabditis elegans Proteins/genetics, Model Organisms, Genetic, DNA-binding proteins, Polycomb-Group Proteins/genetics, medicine, Genetics, Animals, RNA, Messenger, Caenorhabditis elegans Proteins, Molecular Biology, Gene, Ecology, Evolution, Behavior and Systematics, Spermatid, Organisms, Biology and Life Sciences, Proteins, Histone-Lysine N-Methyltransferase, Cell Biology, biology.organism_classification, Invertebrates, Sperm, Nuclear Proteins/genetics, lcsh:Genetics, 030104 developmental biology, Fertility, Germ Cells, Gene Expression Regulation, Caenorhabditis, Fertility/genetics, RNA, Messenger/genetics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e23adbe2d2c59a328fe97305d770d0Test
http://europepmc.org/articles/PMC5942854?pdf=renderTest

المؤلفون: Bogdan Budnik, Alexander van Oudenaarden, Nikolai Slavov, David J. Schwab, Edoardo M. Airoldi

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, Slavov, Nikolai, van Oudenaarden, Alexander, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Slavov
Cell Reports, 7(3), 705-14. Cell Press
Cell Reports, Vol 7, Iss 3, Pp 705-714 (2014)

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Citric Acid Cycle, Messenger, Saccharomyces cerevisiae, Oxidative phosphorylation, Mitochondrion, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Respiration, Glycolysis, RNA, Messenger, Biomass, lcsh:QH301-705.5, Protein Processing, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Post-Translational, Mitochondria, Citric acid cycle, lcsh:Biology (General), Biochemistry, Batch Cell Culture Techniques, Anaerobic glycolysis, RNA, Fermentation, Energy Metabolism, Respiration rate, Protein Processing, Post-Translational, NADP, 030217 neurology & neurosurgery, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ff3428a8dca65ddc589fc6a884489cTest
https://doi.org/10.1016/j.celrep.2014.03.057Test

المؤلفون: Hamsika Chandrasekar, Sangeeta N. Bhatia, Robert E. Schwartz, Timothy P. Sheahan, Mei Lyn Ong, Alexander van Oudenaarden, Kartik Trehan, Christine Espiritu, Kathleen Christine, Vyas Ramanan, Hans Heinrich Hoffmann, Charles M. Rice, Joseph M. Luna

المساهمون: Institute for Medical Engineering and Science, Harvard-MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology. Computational and Systems Biology Program, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, Ramanan, Vyas, Trehan, Kartik, Ong, Mei Lyn, Chandrasekar, Hamsika, Schwartz, Robert E, Christine, Kathleen, van Oudenaarden, Alexander, Bhatia, Sangeeta N, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: PMC
Virology, 494, 236. Academic Press Inc.
Virology, 494, 236-47. Academic Press

مصطلحات موضوعية: 0301 basic medicine, Daclatasvir, Hepatitis C virus, viruses, Genome, Viral, Hepacivirus, Host-virus interactions, Viral Nonstructural Proteins, Biology, Virus Replication, medicine.disease_cause, Antiviral Agents, Article, Cell Line, Single-molecule FISH, 03 medical and health sciences, Interferon, Virology, medicine, Viral replication, Journal Article, Humans, NS5A, Gene, In Situ Hybridization, Fluorescence, RNA virus, biology.organism_classification, Hepatitis C, Molecular Imaging, 030104 developmental biology, Microscopy, Fluorescence, Host-Pathogen Interactions, Immunology, HCV, RNA, Viral, Single-Cell Analysis, Viral load, medicine.drug

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241b28eef4ffa3f80720396ccfea8021Test
https://orcid.org/0000-0001-6214-4788Test

المؤلفون: Guogang Dong, Susan S. Golden, Alexander van Oudenaarden, Qiong Yang, Bernardo F. Pando

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Yang, Qiong, Pando, Bernardo Fabian, van Oudenaarden, Alexander

المصدر: PubMed Central

مصطلحات موضوعية: Cyanobacteria, Light, Cell division, Gating, Models, Biological, Article, Bacterial Proteins, Biological Clocks, Botany, Computer Simulation, Circadian rhythm, Synechococcus, Multidisciplinary, biology, Circadian Rhythm Signaling Peptides and Proteins, Cell Cycle, Cell cycle, biology.organism_classification, Bacterial circadian rhythms, Circadian Rhythm, Cell biology, Luminescent Proteins, Microscopy, Fluorescence, Monte Carlo Method, Function (biology)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a1127560739ddfcc4f39b26101f7edTest
https://doi.org/10.1126/science.1181759Test