نتائج البحث - "transcription factor Nrf2"

1

On the Clinical Pharmacology of Reactive Oxygen Species

المؤلفون: Vincent Jaquet, Moises Di Sante, Ana I. Casas, Fabio Di Lisa, Alexandra Petraina, Nina Kaludercic, François Dufrasne, Antonio Cuadrado, Jalal Soubhye, Soni Deshwal, Cristian Nogales, Ana I. Rojo, Harald H.H.W. Schmidt, Hermann Mucke, Fiona Augsburger, Pietro Ghezzi

المساهمون: European Commission, European Research Council, Maastricht University

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
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Pharmacological reviews, 72 (4
Pharmacological Reviews

مصطلحات موضوعية: 0301 basic medicine, XANTHINE-OXIDASE, TRANSCRIPTION FACTOR NRF2, Disease, Biology, Antioxidants, AMYOTROPHIC-LATERAL-SCLEROSIS, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, SERUM URIC-ACID, SOLUBLE GUANYLATE-CYCLASE, Animals, Humans, Pharmacological modulation, Enzyme Inhibitors, NITRIC-OXIDE SYNTHASE, Chimie pharmaceutique, VITAMIN-E, Randomized Controlled Trials as Topic, Pharmacology, chemistry.chemical_classification, Reactive oxygen species, Clinical pharmacology, Mechanism (biology), Drug discovery, NADPH-OXIDASE, MONOAMINE-OXIDASE, 3. Good health, Chimie organique, Oxidative Stress, 030104 developmental biology, Cell metabolism, Drug development, chemistry, CARDIOVASCULAR-DISEASE, Molecular Medicine, Reactive Oxygen Species, Neuroscience, Oxidation-Reduction, 030217 neurology & neurosurgery

وصف الملف: 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b7e0141223de4d4cfb563f53a3d504Test
https://doi.org/10.1124/pr.120.019422Test

2

Nrf2-inducing and HMG-CoA reductase inhibitory activities of a polyphenol-rich fraction of Guazuma ulmifolia leaves

المؤلفون: Waras Nurcholis, Wulan Tri Wahyuni, Mark Hannink, Syamsul Falah, Dimas Andrianto, Valeri V. Mossine, Arthur A. Lelono, Sulistiyani

المصدر: Asian Pacific Journal of Tropical Biomedicine, Vol 9, Iss 9, Pp 389-396 (2019)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4546604cc4b336a66b5e49e57118242Test
http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=9;spage=389;epage=396;aulast=FalahTest

3

p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

المساهمون: Autophagy, Molecular and Integrative Biosciences Research Programme, Biosciences, Biochemistry and Biotechnology

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Autophagosome, P62, General Physics and Astronomy, TRANSCRIPTION FACTOR NRF2, Plasma protein binding, 0302 clinical medicine, Ubiquitin, Sequestosome-1 Protein, PHOSPHORYLATION, ELECTRON-MICROSCOPY, Kelch-Like ECH-Associated Protein 1, Multidisciplinary, biology, Chemistry, 3. Good health, Cell biology, Liver, Phosphorylation, Microtubule-Associated Proteins, Protein Binding, STRUCTURAL BASIS, NF-E2-Related Factor 2, Science, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Macroautophagy, Autophagy, Animals, Humans, SELECTIVE AUTOPHAGY, Transcription factor, Unilamellar Liposomes, Autophagosomes, RECOGNITION, General Chemistry, DEGRADATION, KEAP1, GENE, Mice, Inbred C57BL, Oxidative Stress, MICE, 030104 developmental biology, Hepatocytes, biology.protein, 1182 Biochemistry, cell and molecular biology, Apoptosis Regulatory Proteins, Lysosomes, Gels, 030217 neurology & neurosurgery, Biogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfb4be4fea4d888a2f39fe826705fd3Test
http://hdl.handle.net/10138/333044Test

4

Isolated and Syndromic Retinal Dystrophy Caused by Biallelic Mutations in RCBTB1 , a Gene Implicated in Ubiquitination

المساهمون: Institut des Neurosciences de Montpellier - Déficits sensoriels et moteurs (INM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)

المصدر: American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2016, 99 (2), pp.470-480. ⟨10.1016/j.ajhg.2016.06.017⟩
American journal of human genetics, vol. 99, no. 2, pp. 470-480
American journal of human genetics, 99 (2
AMERICAN JOURNAL OF HUMAN GENETICS

مصطلحات موضوعية: 0301 basic medicine, Male, Génétique clinique, Turkey, TRANSCRIPTION FACTOR NRF2, PROTEIN, 030105 genetics & heredity, medicine.disease_cause, Consanguinity, Medicine and Health Sciences, CONJUGATING ENZYME, Missense mutation, Guanine Nucleotide Exchange Factors, Exome, Genetics(clinical), Lymphocytes, Age of Onset, Child, Genetics (clinical), Genetics, Mutation, CHROMOSOME 13Q14, Homozygote, EPITHELIAL-CELLS, DOMINANT RETINITIS-PIGMENTOSA, Syndrome, Disease gene identification, Cullin Proteins, Founder Effect, 3. Good health, Pedigree, Phenotype, Female, PROTEASOME SYSTEM, Biologie, Adult, Adolescent, NF-E2-Related Factor 2, Mutation, Missense, Genes, Recessive, Biology, Retina, 03 medical and health sciences, Report, Retinitis pigmentosa, Retinal Dystrophies, medicine, Humans, RNA, Messenger, Allele, Alleles, CHRONIC LYMPHOCYTIC-LEUKEMIA, RESPONSE ELEMENT, Haplotype, Ubiquitination, Biology and Life Sciences, medicine.disease, Molecular biology, 030104 developmental biology, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Haplotypes, Cullin Proteins/metabolism, Exome/genetics, Guanine Nucleotide Exchange Factors/genetics, Haplotypes/genetics, Lymphocytes/metabolism, Mutation, Missense/genetics, NF-E2-Related Factor 2/metabolism, RNA, Messenger/genetics, Retina/metabolism, Retinal Dystrophies/genetics, Ubiquitination/genetics, EXPRESSION ANALYSIS, Founder effect

وصف الملف: application/pdf; 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901a01da159db26ef9653517b759829dTest

5

Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models

المؤلفون: Mirjam M. Schaap, E. van Someren, Peter C. J. Schmeits, Peter J.M. Hendriksen, M. Luijten, Ad A. C. M. Peijnenburg, H. van Loveren, André Boorsma

المساهمون: Promovendi ODB, Gezondheidsvoorlichting, Toxicogenomics, GezondheidsRisico Analyse en Toxicologie, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy

المصدر: Archives of Toxicology, 12, 89, 2325-2337
Archives of Toxicology, 89(12), 2325-2337
Archives of Toxicology 89 (2015) 12
Archives of Toxicology, 89(12), 2325-2337. Springer

مصطلحات موضوعية: Male, Interspecies comparison, Mouse, Novel Foods & Agrochains, Health, Toxicology and Mutagenesis, RAPID - Risk Analysis for Products in Development, C57BL/6, Biomedical Innovation, Toxicology, Novel Foods & Agroketens, Jurkat cells, Interleukin 2, Unfolded protein response, Jurkat Cells, Mice, In vivo study, Life, Cytotoxic T cell, Immunotoxicity, BU Toxicology, Novel Foods & Agrochains, Splenocytes, Messenger RNA, BU Toxicology, General Medicine, Hep G2 Cells, Cell cycle, Endoplasmic Reticulum Stress, Cell biology, Up-Regulation, CTLL-2, medicine.anatomical_structure, BU Toxicologie, Novel Foods & Agroketens, Cyclosporine, Endoplasmic reticulum stress, Animal cell, Healthy Living, Immunosuppressive Agents, medicine.drug, Human, Cell type, Thymoma, Dpleen cell, BU Toxicologie, T cell, Down-Regulation, Down regulation, Biology, T lymphocyte activation, Cell Line, Thymoma cell line, Transcription factor Nrf2, Cyclosporine A, In vivo, Cell Line, Tumor, Upregulation, medicine, Animals, Humans, Animal experiment, Immune response, Transcriptomics, Protein Unfolding, HepG2 cell line, Cytotoxic T lymphocyte, Gene Expression Profiling, In vitro study, Nonhuman, Jurkat cell line, Mice, Inbred C57BL, Human cell, Cell culture, ELSS - Earth, Life and Social Sciences, Cell cycle regulation, Controlled study, Spleen, T-Lymphocytes, Cytotoxic