المؤلفون: Griera Merino, Mercedes, Hatem Vaquero, Marco Antonio, Campillo de Blas, Sofía, Gutiérrez Calabrés, Elena, García Ayuso, Diego, Pardo, María, Calleros Basilio, Laura, Rodríguez Puyol, Manuel, Rodríguez Puyol, Diego María, Frutos García, Sergio de

المساهمون: Universidad de Alcalá. Departamento de Biología de Sistemas

مصطلحات موضوعية: Tirofban, Integrin-beta1, Integrin-linked kinase, AKT, Adipogenesis, Obesity, Hypertrophic adipocyte, Browning, White adipose tissue, Lipolysis, Inflammation, Biología y Biomedicina, Biology

وصف الملف: application/pdf

العلاقة: Info:eu-repo/grantAgreement/MINECO/ Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI14%2F01939/ES/PAPEL DE LA KINASA LIGADA A INTEGRINAS EN LAS ALTERACIONES DEL METABOLISMO DE LOS HIDRATOS DE CARBONO Y EN LA GÉNESIS DEL DAÑO TISULAR ASOCIADO/; info:eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI14%2F02075/ES/Importancia de la Kinasa Ligada a Integrinas en la progresión de la enfermedad renal crónica (ERC) y en la génesis del daño vascular asociado a la misma/; info.eu-repo/grantAgreement/MINECO/Programa Estatal de I+D+I Orientada a los Retos de la Sociedad/PI17%2F01513/ES/Kinasa ligada a integrinas: posible biomarcador de progresión de la enfermedad renal crónica (ERC) y modulador de la disfunción monocitaria responsable del daño cardiovascular/; info:eu-repo/grantAgreement/MINECO/Acción estratégica en Salud 2013-2016/PI17%2F00625/ES/Kinasa ligada a integrinas: papel en la progresión de la resistencia a la insulina y en el desarrollo de la obesidad/; info:eu-repo/grantAgreement/MINECO/Acción estratégica de Salud 2013-2016//ES/PI20%2F00634; info:eu-repo/grantAgreement/CAM//S2017%2FBMD-3751/ES/ENFERMEDAD RENAL CRÓNICA. NUEVAS ESTRATEGIAS PARA LA PREVENCIÓN, DIAGNÓSTICO Y TRATAMIENTO/; info:eu-repo/grantAgreement/MINECO/PN de I+D+I/RD12%2F0021%2F0006/ES/Enfermedades Renales/; info:eu-repo/grantAgreement/MINECO/ISCIII/RD16%2F0009%2F0018/ES/Red de Investigacion Renal REDINREN/; de Frutos, S., Griera, M., Hatem-Vaquero, M. et al. The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo. Cell Biosci 12, 10 (2022).; http://hdl.handle.net/10017/50868Test; AR/0000037821; Cell and Bioscience; 12; 18; 10

الإتاحة: https://doi.org/10.1186/s13578-022-00746-1Test
http://hdl.handle.net/10017/50868Test

المؤلفون: Manuel Rodríguez-Puyol, Javier García-Marín, Sergio de Frutos, Ramón Alajarín, Juan J. Vaquero, Mercedes Griera-Merino, Diego Rodríguez-Puyol, Alejandra Matamoros-Recio

المساهمون: Universidad de Alcalá. Departamento de Medicina y Especialidades Médicas, Universidad de Alcalá. Departamento de Biología de Sistemas, Universidad de Alcalá. Departamento de Química Orgánica y Química Inorgánica

المصدر: e_Buah Biblioteca Digital Universidad de Alcalá
instname
ACS Medicinal Chemistry Letters

مصطلحات موضوعية: Letter, tripeptide, protein−protein interaction, Tripeptide, Molecular Dynamics, Biochemistry, Protein–protein interaction, hot spot, Solid Phase Peptide Synthesis, Chronic Kidney Disease, Drug Discovery, Signaling process, Integrin-linked kinase, parvin, integrin-linked kinase, biology, Kinase, Chemistry, Organic Chemistry, A protein, Química, Cell biology, Peptide, embryonic structures, biology.protein, ILK, chronic kidney disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a480163747e797ecdeb2ada9caae324Test
https://doi.org/10.1021/acsmedchemlett.1c00183Test

المؤلفون: Lee, Su-Lin¹, Chou, Chih-Chien¹, Chuang, Hsiao-Ching¹, Hsu, En-Chi¹, Chiu, Po-Chen¹, Kulp, Samuel K.¹, Byrd, John C.^1,2, Chen, Ching-Shih^1,3 chen.844@osu.edu

المصدر: PLoS ONE. Jun2013, Vol. 8 Issue 6, p1-11. 11p.

مصطلحات موضوعية: *INTEGRIN-linked kinase, *BREAST cancer, *PHOSPHORYLATION, *MTOR protein, *PTEN protein, *PROSTATE cancer, *PHOSPHOINOSITIDE-dependent kinase-1, *CANCER cells

المؤلفون: F. Graeter, M. M. Nava, S. A. Wickstroem, I. M. Martin

المساهمون: STEMM - Stem Cells and Metabolism Research Program, Helsinki Institute of Life Science HiLIFE, University of Helsinki

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Models, Molecular, STRUCTURAL BASIS, Allosteric regulation, PINCH, Molecular Conformation, Protein Serine-Threonine Kinases, Mechanotransduction, Cellular, Traction force microscopy, Substrate Specificity, Extracellular matrix, Focal adhesion, Structure-Activity Relationship, Adenosine Triphosphate, Allosteric Regulation, DOMAIN, Cell Movement, Enzyme Stability, BINDING, Cell Adhesion, Protein Interaction Domains and Motifs, Integrin-linked kinase, focal adhesion, Cytoskeleton, Cell adhesion, Focal Adhesions, Multidisciplinary, Binding Sites, integrin-linked kinase, biology, THERAPEUTIC TARGET, Chemistry, Microfilament Proteins, LOCALIZATION, Actomyosin, Adhesion, traction force microscopy, molecular dynamics, KINDLIN-2, embryonic structures, Mutation, Biophysics, biology.protein, 1182 Biochemistry, cell and molecular biology, ALPHA-PARVIN, ILK, CELL-ADHESION, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f89c1d25acb3fa60a0ac21b98e128b9Test
http://hdl.handle.net/10138/347201Test

المؤلفون: Celeste M. Nelson, Emann M Rabie, Sherry X. Zhang, Connor E. Dunn

المصدر: Molecular Biology of the Cell

مصطلحات موضوعية: Epithelial-Mesenchymal Transition, Acrylic Resins, Cell Culture Techniques, Kinesins, Breast Neoplasms, Protein Serine-Threonine Kinases, Mice, Mammary Glands, Animal, Abscission, Transforming Growth Factor beta, Tumor Microenvironment, Animals, Integrin-linked kinase, Molecular Biology, Focal Adhesions, biology, Transition (genetics), Kinase, Integrin beta1, β1 integrin, Epithelial Cells, Articles, Cell Biology, Extracellular Matrix, Cell biology, Midbody, embryonic structures, biology.protein, Female, Snail Family Transcription Factors, Septins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aabde3868c45601b0e7f0d43616721dTest
https://doi.org/10.1091/mbc.e21-02-0072Test

المؤلفون: Don C. Rockey, Mahnoush S. Shafiei

المصدر: Laboratory Investigation. 102:112-114

مصطلحات موضوعية: Text mining, biology, business.industry, Chemistry, Hepatic stellate cell, biology.protein, Integrin-linked kinase, Cell Biology, business, Molecular Biology, Function (biology), Pathology and Forensic Medicine, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c874ffb588b8a9c816a4e86d6398ee8bTest
https://doi.org/10.1038/s41374-021-00659-6Test

المؤلفون: Jian-ming Liu, Jing-xuan Xie, Hui Jiang, Jun-hong Deng, Zhou-da Cai, Bin Ouyang, Zi-bin Lin, Yan-ni Wei, Liang-liang Huang

المصدر: Stem Cells International, Vol 2021 (2021)

مصطلحات موضوعية: Article Subject, biology, Myogenesis, Cellular differentiation, NF-κB, Cell Biology, RC31-1245, Cell biology, chemistry.chemical_compound, chemistry, Downregulation and upregulation, Cell culture, embryonic structures, biology.protein, Integrin-linked kinase, Signal transduction, Stem cell, Internal medicine, Molecular Biology

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cf397143ed42bdb0155380c6118affTest
https://doi.org/10.1155/2021/6633111Test

المؤلفون: Cong Huang, Gang Song, Liqun Zhou, Qi Shen, Shiming He

المصدر: Transl Androl Urol

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Gene knockdown, biology, Kinase, Microarray analysis techniques, Urology, medicine.disease, Metastasis, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Reproductive Medicine, 030220 oncology & carcinogenesis, parasitic diseases, Gene expression, biology.protein, medicine, Cancer research, Original Article, Integrin-linked kinase, Protein kinase A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208043fbdfc416665acfb0331b341002Test
https://doi.org/10.21037/tau-21-108Test

المؤلفون: Hongyan Lv, Fanyun Zeng, Baojun Zhou, Liyuan Chen, Kongxing Wei, Yan Li, Jieliang Hu, Jinglei Wang

المصدر: Journal of Biomaterials and Tissue Engineering. 11:344-349

مصطلحات موضوعية: biology, Chemistry, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Bone marrow mesenchymal stem cells, Cell biology, stomatognathic system, Mitogen-activated protein kinase, Protein kinase B signaling, embryonic structures, biology.protein, Integrin-linked kinase, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::62e3ed50f7c66fb61040ad57758d0d04Test
https://doi.org/10.1166/jbt.2021.2559Test

المؤلفون: Wei Zheng, Qizhen Tang, Feng Chen, Shi Li, Jie Qin, Tao Huang

المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: medicine.medical_specialty, Antioxidant, hypertension, medicine.medical_treatment, H&E stain, Astragalus polysaccharides, Renal function, renal damage, RM1-950, urologic and male genital diseases, chemistry.chemical_compound, integrin linked kinase, Internal medicine, medicine, Renal fibrosis, Pharmacology (medical), Integrin-linked kinase, Original Research, Pharmacology, Creatinine, biology, transforming growth factor-β, Angiotensin II, Endocrinology, chemistry, biology.protein, Uric acid, Therapeutics. Pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8417656686f5062c32ab4720e51868a3Test
http://europepmc.org/articles/PMC8527034Test