-
1
المؤلفون: Nobumichi Ohoka, Muneshige Tokugawa, Hidetoshi Hayashi, Masayuki Komada, Yasumichi Inoue, Shin Watanabe, Daisuke Morishita, Chiharu Miyajima, Keishi Fukuura
المصدر: J Biol Chem
مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, 0301 basic medicine, Senescence, Aging, Ubiquitin-Protein Ligases, Biochemistry, Cell Line, Histones, Histone H4, 03 medical and health sciences, Ubiquitin, Chlorocebus aethiops, Endopeptidases, Histone methylation, Animals, Humans, Molecular Biology, Cell Proliferation, Gene knockdown, 030102 biochemistry & molecular biology, biology, Kinase, Cell growth, Chemistry, Cell Cycle, Ubiquitination, Histone-Lysine N-Methyltransferase, Methyltransferases, Cell Biology, Cell cycle, HCT116 Cells, Cell biology, 030104 developmental biology, Protein Synthesis and Degradation, COS Cells, MCF-7 Cells, biology.protein, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5215caa0554c13cf61ee1ea274772bTest
https://doi.org/10.1074/jbc.ra119.009006Test -
2
المؤلفون: Keiji Miyazawa, Yasumichi Inoue, Takuya Aoshima, Chiharu Uchida, Masatoshi Kitagawa, Tatsuya Ohhata, Kyoko Kitagawa, Satoshi Sakai, Hiroyuki Niida, Tetsuro Suzuki
المصدر: Cancer Research. 79:2821-2838
مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, Cancer Research, Regulator, RNA, Promoter, SMAD, Biology, Long non-coding RNA, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Epithelial–mesenchymal transition, Transcription factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::207f16e85c0b093613bfbde618ee8c33Test
https://doi.org/10.1158/0008-5472.can-18-3210Test -
3
المؤلفون: Nobumichi Ohoka, Muneshige Tokugawa, Mai Nagasaka, Kaori Tsuzuki, Yasumichi Inoue, Hidetoshi Hayashi, Yu Ozeki
المصدر: Biological and Pharmaceutical Bulletin. 42:481-488
مصطلحات موضوعية: 0301 basic medicine, Histone H3 Lysine 4, animal structures, Databases, Factual, Pharmaceutical Science, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Cell Line, Tumor, Humans, Histone Demethylases, Pharmacology, Gene knockdown, biology, Chemistry, KDM1A, General Medicine, Molecular biology, 030104 developmental biology, Histone, 030220 oncology & carcinogenesis, Transcription preinitiation complex, Neoplastic Stem Cells, biology.protein, Demethylase, RNA Interference, Chromatin immunoprecipitation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a646ae1800c35daf91b020e298aa3cTest
https://doi.org/10.1248/bpb.b18-00892Test -
4An irreversible inhibitor of peptidyl-prolyl cis/trans isomerase Pin1 and evaluation of cytotoxicity
المؤلفون: Hidehiko Nakagawa, Yasumichi Inoue, Naoki Miyata, Yusuke Izumiya, Naoya Ieda, Kaoru Itoh, Mitusyasu Kawaguchi
المصدر: Bioorganic & Medicinal Chemistry Letters. 29:353-356
مصطلحات موضوعية: Cell Survival, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Isomerase, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Cyclin D1, Drug Discovery, Prolyl isomerase, Humans, Enzyme Inhibitors, Cytotoxicity, Molecular Biology, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Cell growth, Organic Chemistry, Active site, HCT116 Cells, 0104 chemical sciences, NIMA-Interacting Peptidylprolyl Isomerase, 010404 medicinal & biomolecular chemistry, Covalent bond, PC-3 Cells, PIN1, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a01515a349b7c25ccd19a52491e71c5Test
https://doi.org/10.1016/j.bmcl.2018.12.044Test -
5
المؤلفون: Hidetoshi Hayashi, Nobumichi Ohoka, Yuki Kawarada, Daisuke Morishita, Chiaki Suzuki, Yasumichi Inoue, Kana Mitamura, Takeshi Imamura, Chiharu Miyajima
المصدر: Cells, Vol 9, Iss 1, p 171 (2020)
Cells
Cells; Volume 9; Issue 1; Pages: 171مصطلحات موضوعية: p53, Transcription, Genetic, Regulator, p300, Biology, medicine.disease_cause, Models, Biological, Article, Cell Line, law.invention, law, oncogene, Gene expression, medicine, Humans, cellular senescence, lcsh:QH301-705.5, Hippo signaling pathway, Gene knockdown, taz, Oncogene, Cell growth, Acetylation, DNA, General Medicine, Fibroblasts, Cell biology, TAZ, lcsh:Biology (General), Transcriptional Coactivator with PDZ-Binding Motif Proteins, Trans-Activators, Suppressor, Tumor Suppressor Protein p53, Carcinogenesis, E1A-Associated p300 Protein, Protein Binding
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d44d41a7c89e1551f3d8177f956fbeTest
https://www.mdpi.com/2073-4409/9/1/171Test -
6Regulation of Epithelial-Mesenchymal Transition by E3 Ubiquitin Ligases and Deubiquitinase in Cancer
المؤلفون: Takahito Tanaka, Chihiro Sumita, Hidetoshi Hayashi, Yasumichi Inoue, Fumihiro Kawasaki, Daisuke Morishita, Yuka Itoh, Koichi Sato
المصدر: Current Cancer Drug Targets. 16:110-118
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Cancer Research, Epithelial-Mesenchymal Transition, Ubiquitin-Protein Ligases, Antineoplastic Agents, Bioinformatics, Gene Expression Regulation, Enzymologic, Deubiquitinating enzyme, 03 medical and health sciences, Ubiquitin, Neoplasms, Drug Discovery, medicine, Animals, Humans, Molecular Targeted Therapy, Epithelial–mesenchymal transition, Transcription factor, Pharmacology, Regulation of gene expression, biology, Protein Stability, Ubiquitination, Cancer, Cell migration, medicine.disease, Cell biology, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Drug Design, Proteolysis, embryonic structures, biology.protein, Ubiquitin-Specific Proteases, Signal transduction, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afe4c6511829e43a78080c460b91dacTest
https://doi.org/10.2174/1568009616666151112122126Test -
7
المؤلفون: Daisuke Morishita, Ken-ichi Nakashima, Nobumichi Ohoka, Sakiko Nishikawa, Yasumichi Inoue, Toshiaki Makino, Muneshige Tokugawa, Makoto Inoue, Kou Yoshida, Hidetoshi Hayashi, Hajime Mizukami, Yuka Itoh, Yuka Hori, Chiharu Miyajima
المصدر: Molecules
Volume 24
Issue 17
Molecules, Vol 24, Iss 17, p 3110 (2019)مصطلحات موضوعية: PERK, TRB3, Cell, Pharmaceutical Science, Pharmacology, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, 0302 clinical medicine, lcsh:Organic chemistry, Drug Discovery, medicine, cancer, ATF4, Sophora flavescens, ISR, Physical and Theoretical Chemistry, 030304 developmental biology, 0303 health sciences, biology, Kinase, Chemistry, Endoplasmic reticulum, Organic Chemistry, kurarinone, biology.organism_classification, Cytostasis, medicine.anatomical_structure, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Cancer cell, Molecular Medicine, Phosphorylation
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c588b1d895224dc5016fbe6ef782cd85Test
https://doi.org/10.3390/molecules24173110Test -
8
المؤلفون: Daisuke Morishita, Nobumichi Ohoka, Keishi Fukuura, Yuka Itoh, Mai Nagasaka, Hidetoshi Hayashi, Shogo Ito, Shiori Kawachi, Tsubasa Ohkubo, Yasumichi Inoue
المصدر: FEBS letters. 591(21)
مصطلحات موضوعية: 0301 basic medicine, Cyclin-Dependent Kinase Inhibitor p21, Cell Survival, Biophysics, Cell fate determination, Activating Transcription Factor 4, Biology, Response Elements, Biochemistry, 03 medical and health sciences, Structural Biology, Genetics, Humans, Molecular Biology, Gene knockdown, Effector, Endoplasmic reticulum, ATF4, Cell Biology, Endoplasmic Reticulum Stress, Introns, 030104 developmental biology, Cancer research, Unfolded protein response, MCF-7 Cells, CDK inhibitor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e0cf0f52bafc74a4db1a697832d00cTest
https://pubmed.ncbi.nlm.nih.gov/28975618Test -
9
المؤلفون: Fumihiro Kawasaki, Koichi Sato, Yuki Kawarada, Takahito Tanaka, Keishi Fukuura, Yasumichi Inoue, Hidetoshi Hayashi, Yuka Itoh
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Transcriptional Activation, Sialoglycoproteins, Response element, Smad Proteins, SMAD, medicine.disease_cause, Response Elements, Article, Cell Line, 03 medical and health sciences, Transforming Growth Factor beta, Plasminogen Activator Inhibitor 1, medicine, Humans, Protein Interaction Domains and Motifs, Histone H3 acetylation, Promoter Regions, Genetic, R-SMAD, Multidisciplinary, biology, Chemistry, Transforming growth factor beta, Histone acetyltransferase, Cytostasis, Peptide Fragments, Cell biology, 030104 developmental biology, Multiprotein Complexes, biology.protein, Tumor Suppressor Protein p53, Carcinogenesis, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c06327da419fe1f98fbdc812695e9baTest
https://pubmed.ncbi.nlm.nih.gov/27759037Test -
10
المؤلفون: Asako Sakaue-Sawano, Hisashi Yoshimi, Yumiko Mukai, Takao Yamori, Atsushi Miyawaki, Mutsumi Okamura, Aki Hanyu, Takeshi Imamura, Yasumichi Inoue, Shingo Dan
المصدر: European Journal of Cancer. 48:936-943
مصطلحات موضوعية: Cancer Research, Uterine Cervical Neoplasms, Apoptosis, Breast Neoplasms, Pharmacology, HeLa, Mice, chemistry.chemical_compound, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Phosphatidylinositol, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Mice, Inbred BALB C, biology, Triazines, Cell growth, Cell Cycle, G1 Phase, Cancer, Cell cycle, medicine.disease, biology.organism_classification, Xenograft Model Antitumor Assays, Oncology, chemistry, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d4fe7ff6c69d7b93b0f152608b3bbaTest
https://doi.org/10.1016/j.ejca.2011.10.006Test