المؤلفون: Xinhua Zhan, Lanying Song, Sheng Zhang, Fuzheng Guo, Jennifer McDonough, Yan Wang, Franca Cambi, Hui Fu, Xiaoqing Zhu, Judith B. Grinspan, Edric Ma

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 8
J Neurosci

مصطلحات موضوعية: 0301 basic medicine, endocrine system diseases, Bone Morphogenetic Protein 4, Neurodegenerative, Inbred C57BL, Regenerative Medicine, Medical and Health Sciences, Transgenic, Mice, 0302 clinical medicine, Demyelinating disease, 2.1 Biological and endogenous factors, Aetiology, Research Articles, Effector, General Neuroscience, Wnt signaling pathway, Brain, myelination, Cell Differentiation, Cell biology, Oligodendroglia, Autocrine Communication, medicine.anatomical_structure, Neurological, BMP4 repression, Transcription Factor 7-Like 2 Protein, Multiple Sclerosis, canonical Wnt/β-catenin, Neurogenesis, Mice, Transgenic, Wnt effector, Biology, Bone morphogenetic protein, Autoimmune Disease, 03 medical and health sciences, Downregulation and upregulation, Genetics, medicine, Animals, canonical Wnt/beta-catenin, Remyelination, Autocrine signalling, Transcription factor, Oligodendrocyte Precursor Cells, Neurology & Neurosurgery, Psychology and Cognitive Sciences, Neurosciences, Oligodendrocyte differentiation, medicine.disease, Oligodendrocyte, Brain Disorders, Mice, Inbred C57BL, oligodendrocyte differentiation, 030104 developmental biology, Gene Expression Regulation, TCF7l2/TCF4, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e672ea86375acffb8d16833b55e174cTest
https://doi.org/10.1101/2020.09.16.300624Test

المؤلفون: Yoshihiro Takemoto, Hiroshi Kurazumi, Arata Nishimoto, Kimikazu Hamano, Bungo Shirasawa, Toshiki Tanaka, Toshiro Saito, Eijiro Harada

المصدر: Biochemical and biophysical research communications. 533(3)

مصطلحات موضوعية: 0301 basic medicine, T cell, Biophysics, medicine.disease_cause, Biochemistry, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, 0302 clinical medicine, Ubiquitin, Cell Line, Tumor, medicine, Humans, Poly-ADP-Ribose Binding Proteins, Molecular Biology, beta Catenin, Cell Nucleus, biology, Chemistry, COP9 Signalosome Complex, Wnt signaling pathway, Intracellular Signaling Peptides and Proteins, Cell Biology, TCF4, Cell cycle, Cell biology, Ubiquitin ligase, 030104 developmental biology, medicine.anatomical_structure, DNA Topoisomerases, Type II, Ki-67 Antigen, 030220 oncology & carcinogenesis, Catenin, biology.protein, Carcinogenesis, Colorectal Neoplasms, Transcription Factor 7-Like 2 Protein, Peptide Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da2ceef862a279ca580142aa4e30740Test
https://pubmed.ncbi.nlm.nih.gov/32977947Test

المؤلفون: Kunal Karve, Lili Deng, Shirin Bonni, Stuart J. Netherton, Azad Bonni

المصدر: Cell Death and Disease, Vol 11, Iss 8, Pp 1-20 (2020)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Gene isoform, Cancer Research, Epithelial-Mesenchymal Transition, endocrine system diseases, Molecular biology, Immunology, Morphogenesis, Article, Cell Line, Transforming Growth Factor beta1, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Transforming Growth Factor beta, Animals, Humans, Protein Isoforms, Smad3 Protein, Epithelial–mesenchymal transition, lcsh:QH573-671, Transcription factor, biology, lcsh:Cytology, Alternative splicing, nutritional and metabolic diseases, Epithelial Cells, Cell Biology, Transforming growth factor beta, Cell biology, Organoids, 030104 developmental biology, 030220 oncology & carcinogenesis, RNA splicing, biology.protein, Signal transduction, Transcription Factor 7-Like 2 Protein, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff8c84683a40d6d758d7e33d6d2ef2bTest
https://doi.org/10.1038/s41419-020-02905-zTest

المؤلفون: Leila Najd Hassan Bonab, Asiyeh Sadat Zahedi, Maryam Moazzam-Jazi, Maryam S. Daneshpour

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Population, lcsh:Medicine, Single-nucleotide polymorphism, Diseases, Disease, Biology, Iran, Polymorphism, Single Nucleotide, Article, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Medical research, Gene Frequency, Risk Factors, Genetics, Prevalence, Humans, Genetic Predisposition to Disease, Longitudinal Studies, Allele, education, lcsh:Science, Allele frequency, Alleles, education.field_of_study, Multidisciplinary, Molecular medicine, lcsh:R, Middle Aged, 030104 developmental biology, Diabetes Mellitus, Type 2, Cohort, lcsh:Q, Female, TCF7L2, Transcription Factor 7-Like 2 Protein, 030217 neurology & neurosurgery, Demography, Cohort study, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad450f658f9393723b9ef7c611286cbeTest
http://europepmc.org/articles/PMC7438483Test

المؤلفون: Katarzyna A. Lisowska, Zbigniew Zdrojewski, Michał Pikuła, Żaneta Smoleńska, Anna Wardowska

المصدر: Acta biochimica Polonica. 67(3)

مصطلحات موضوعية: Adult, Male, Myeloid, medicine.medical_treatment, Tumor Necrosis Factor Ligand Superfamily Member 13, Polymerase Chain Reaction, Severity of Illness Index, General Biochemistry, Genetics and Molecular Biology, Immune tolerance, Pathogenesis, medicine, Humans, Lupus Erythematosus, Systemic, Myeloid Cells, skin and connective tissue diseases, Autoimmune disease, biology, business.industry, Autoantibody, Dendritic Cells, Middle Aged, medicine.disease, Flow Cytometry, DNA-Binding Proteins, Cytokine, medicine.anatomical_structure, Phenotype, Case-Control Studies, Immunology, Interferon Regulatory Factors, biology.protein, Female, Antibody, business, Transcriptome, Transcription Factor 7-Like 2 Protein, IRF5

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b02decc3a5f608dd2301d239fa2f283Test
https://pubmed.ncbi.nlm.nih.gov/32730703Test

المؤلفون: Christian Obirikorang, Enoch Odame Anto, Edwin Ferguson Laing, Emmanuel Acheampong, Max Efui Annani-Akollor, Evans Adu Asamoah, Eddie-Williams Owiredu

المصدر: Journal of Diabetes Research
Journal of Diabetes Research, Vol 2020 (2020)

مصطلحات موضوعية: Candidate gene, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Population, Review Article, Biology, Sulfonylurea Receptors, Polymorphism, Single Nucleotide, Diseases of the endocrine glands. Clinical endocrinology, Endocrinology, Humans, Genetic Predisposition to Disease, Family history, Potassium Channels, Inwardly Rectifying, Pyrophosphatases, education, Africa South of the Sahara, Genetics, education.field_of_study, Haptoglobins, Phosphoric Diester Hydrolases, Tumor Necrosis Factor-alpha, nutritional and metabolic diseases, Odds ratio, Heritability, RC648-665, Study heterogeneity, Diabetes Mellitus, Type 2, Meta-analysis, Adiponectin, TCF7L2, Transcription Factor 7-Like 2 Protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365b3227a188b2dca1e65371ed6be418Test
http://europepmc.org/articles/PMC7352126Test

المؤلفون: Claus-Dieter Mayer, Fozan Alsehly, Stefan Hoppler, Soizick Magon de La Giclais

المصدر: Genes
Volume 11
Issue 5
Genes, Vol 11, Iss 538, p 538 (2020)

مصطلحات موضوعية: 0301 basic medicine, Beta-catenin, animal structures, lcsh:QH426-470, Lymphoid Enhancer-Binding Factor 1, Colorectal cancer, Biopsy, Transcription Factor 7-Like 1 Protein, Datasets as Topic, colorectal cancer, Adenocarcinoma, Biology, Article, Wnt, 03 medical and health sciences, 0302 clinical medicine, Axin Protein, Genetics, medicine, AXIN2, Data Mining, Humans, Protein Isoforms, RNA, Messenger, RNA, Neoplasm, Wnt Signaling Pathway, Genetics (clinical), Feedback, Physiological, LEF, LGR5, Wnt signaling pathway, Cancer, TCF, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, lcsh:Genetics, 030104 developmental biology, 030220 oncology & carcinogenesis, embryonic structures, Disease Progression, biology.protein, Cancer research, Colorectal Neoplasms, Transcriptome, Transcription Factor 7-Like 2 Protein, TCF7L2, Extracellular matrix organization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dc87653d509311f2f7ccef65be0739Test
https://eprints.gla.ac.uk/215836/7/215836.pdfTest

المؤلفون: Haiyan Weng, Shilian Hu, Peipei Jin, Xuanxuan Mu, Wen Chen, Xinchun Wu, Liu Fenfen, Guodong Shen, Yan Zhang, Huirong Ren, Dabing Huang, Wu Yin, Tingjuan Xu, Tingting Zhao, Min Cheng, Meng Dai, Gao Qian

المصدر: Biochemical and biophysical research communications. 526(3)

مصطلحات موضوعية: 0301 basic medicine, endocrine system diseases, Receptor, ErbB-2, Carcinoma, Ovarian Epithelial, Biochemistry, HER2/neu, Metastasis, 0302 clinical medicine, Nude mouse, Antineoplastic Agents, Immunological, Trastuzumab, Phosphorylation, RNA, Small Interfering, skin and connective tissue diseases, Wnt Signaling Pathway, beta Catenin, biology, Wnt signaling pathway, Prognosis, female genital diseases and pregnancy complications, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Female, Transcription Factor 7-Like 2 Protein, medicine.drug, Biophysics, Mice, Nude, Transfection, 03 medical and health sciences, Cell Line, Tumor, Wnt3A Protein, medicine, Animals, Humans, RNA, Messenger, Molecular Biology, Protein kinase B, business.industry, Lentivirus, Cell Biology, Neoplasms, Experimental, biology.organism_classification, medicine.disease, 030104 developmental biology, Drug Resistance, Neoplasm, Catenin, biology.protein, Cancer research, business, WNT3A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163cb392958ca5250b17ac728f3f9943Test
https://pubmed.ncbi.nlm.nih.gov/32248976Test

المؤلفون: Joshua W. K. Ho, Richard I. Sherwood, Lendy Chu, Tomasz Szczesnik

المصدر: Cell Systems, 11 (3)
Cell systems

مصطلحات موضوعية: Histology, Locus (genetics), Computational biology, Biology, Genome, Article, DNA sequencing, Pathology and Forensic Medicine, Kruppel-Like Factor 4, chemistry.chemical_compound, 03 medical and health sciences, 0302 clinical medicine, Humans, CRISPR, A-DNA, Transcription factor, 030304 developmental biology, 0303 health sciences, Binding Sites, Effector, Chemistry, Cas9, Cell Biology, High-Throughput Screening Assays, Chromatin, Transcription Factor 7-Like 2 Protein, DNA, 030217 neurology & neurosurgery, Transcription Factors

وصف الملف: application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0e61db6b1a5643086290e2cc99124Test
https://doi.org/10.1101/2020.03.16.993204Test

المؤلفون: Peter Orchard, Jocelyn E. Manning Fox, Anthony Payne, Karen L. Mohlke, Laura J. Scott, Nikolay Oskolkov, Anubha Mahajan, Andrew A. Brown, Apoorva K Iyengar, Paul Johnson, Ola Hansson, Patrick E. MacDonald, Michael L. Stitzel, Ulrika Krus, Ana Viñuela, Cédric Howald, Narisu Narisu, Gad Hatem, Anna L. Gloyn, Nikolaos I Panousis, Michael R. Erdos, Leif Groop, Vibe Nylander, Olof Asplund, João Fadista, Francis S. Collins, Emmanouil T. Dermitzakis, Amanda J. Bennett, Swarooparani Vadlamudi, Arushi Varshney, Rashmi B. Prasad, Stephen C. J. Parker, Mark I. McCarthy, Michael Boehnke, Martijn van de Bunt, Ryan P. Welch

المساهمون: Brown, Andrew Anand, Howald, Cédric, Panousis, Nikolaos, Dermitzakis, Emmanouil, Institute for Molecular Medicine Finland, University of Helsinki, Centre of Excellence in Complex Disease Genetics, HUS Abdominal Center, University Management

المصدر: Nature Communications, Vol. 11, No 1 (2020) P. 4912
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, endocrine system diseases, General Physics and Astronomy, Genome-wide association study, Cohort Studies, Mice, 0302 clinical medicine, ddc:590, Transcriptional regulation, 80 and over, ddc:576.5, RNA-Seq, lcsh:Science, Genetics, Regulation of gene expression, Aged, 80 and over, ARCHITECTURE, Multidisciplinary, geography.geographical_feature_category, Tumor, 1184 Genetics, developmental biology, physiology, Type 2 diabetes, Single Nucleotide, Middle Aged, Islet, OPEN CHROMATIN, Transcription Factor 7-Like 2 Protein/genetics/metabolism, medicine.anatomical_structure, Enhancer Elements, Genetic, Regulatory sequence, Blood Glucose/genetics/metabolism, Female, Islets of Langerhans/metabolism, MESSENGER-RNA, Transcription Factor 7-Like 2 Protein, Sequence Analysis, Type 2/blood/genetics, Adult, BETA-CELL LINE, Diacylglycerol Kinase, endocrine system, Adolescent, Enhancer Elements, Science, Quantitative Trait Loci, Biology, INSULIN-SECRETION, Polymorphism, Single Nucleotide, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, 03 medical and health sciences, Islets of Langerhans, Young Adult, Genetic, Cell Line, Tumor, medicine, GLYCEMIC TRAITS, Diabetes Mellitus, Animals, Humans, Genetic Predisposition to Disease, GENOME-WIDE ASSOCIATION, Polymorphism, SIGNATURES, Genetic association study, Aged, CAUSAL VARIANTS, geography, Pancreatic islets, Data acquisition, General Chemistry, Sequence Analysis, DNA, DNA, Gene regulation, 030104 developmental biology, Diabetes Mellitus, Type 2, Gene Expression Regulation, Diacylglycerol Kinase/genetics/metabolism, Expression quantitative trait loci, lcsh:Q, TYPE-2 DIABETES RISK, 3111 Biomedicine, TCF7L2, 030217 neurology & neurosurgery, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a13e4756f7dc1e58a1b08e7a9f4874Test
https://archive-ouverte.unige.ch/unige:144670Test