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المؤلفون: Ahmed Emad Ibrahim Hamouda, Peter Ettmayer, Gregor Eisenwort, Satu Mustjoki, Giulia Rossetti, Kristina Feldberg, Jens Panse, Frank Hilberg, Anne Kaiser, Marcelo A. S. Toledo, Karoline V. Gleixner, Malrun Gatz, Peter Valent, Angela Maurer, Andreas Reiter, Nicolas Chatain, Herdit M. Schüler, Wolfgang Wagner, Olli Dufva, Riccardo Guareschi, Tim H. Brümmendorf, Roman Goetzke, Martin Zenke, Steffen Koschmieder, Mohamad Jawhar, Frederick Kluge, Till Braunschweig, Antonio Sechi, Stephanie Sontag
المساهمون: TRIMM - Translational Immunology Research Program, Doctoral Programme in Clinical Research, Department of Clinical Chemistry and Hematology, Digital Precision Cancer Medicine (iCAN), HUS Comprehensive Cancer Center, Doctoral Programme in Drug Research, Doctoral Programme in Biomedicine, Research Programs Unit
المصدر: Blood 137(15), 2070-2084 (2021). doi:10.1182/blood.2019004509
مصطلحات موضوعية: MIDOSTAURIN, Indoles, 3122 Cancers, Induced Pluripotent Stem Cells, Immunology, Antineoplastic Agents, IMATINIB, Biochemistry, CLASSIFICATION, Receptor tyrosine kinase, MASITINIB, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mastocytosis, Systemic, Growth factor receptor, Tumor Cells, Cultured, medicine, Humans, Point Mutation, ddc:610, WILD-TYPE, Systemic mastocytosis, Induced pluripotent stem cell, 030304 developmental biology, 0303 health sciences, biology, MUTATIONS, Chemistry, INHIBITOR, Cell Biology, Hematology, Mast cell leukemia, medicine.disease, Embryonic stem cell, 3. Good health, C-KIT, Proto-Oncogene Proteins c-kit, 030220 oncology & carcinogenesis, Cancer research, biology.protein, MAST-CELLS, GROWTH, Nintedanib, Tyrosine kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61b14a38b099caef2f04e66e215ce20Test
https://doi.org/10.1182/blood.2019004509Test -
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المؤلفون: Tim H. Brümmendorf, Nicolas Chatain, Bernd Denecke, Caroline Küstermann, Klaus Strathmann, Tiago Maié, Stephanie Sontag, Martin Zenke, Annika Hubrich, Ivan G. Costa, Julian Baumeister, Andreas Schuppert, Steffen Koschmieder, Deniz Gezer, Kamil R. Kranc, Lijuan Han, Kristin Seré
المصدر: Leukemia. 34:1062-1074
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, Induced Pluripotent Stem Cells, Apoptosis, Echinomycin, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Polycythemia vera, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Humans, Progenitor cell, Myelofibrosis, Aged, Cell Proliferation, Aged, 80 and over, Antibiotics, Antineoplastic, Myeloproliferative Disorders, Essential thrombocythemia, Cell Cycle, Hematology, Janus Kinase 2, Middle Aged, Hypoxia-Inducible Factor 1, alpha Subunit, Prognosis, medicine.disease, Warburg effect, Gene Expression Regulation, Neoplastic, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, Mutation, Cancer research, Female, Bone marrow, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6aed03294806d5f6aee20d52c51eefTest
https://doi.org/10.1038/s41375-019-0629-zTest -
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المؤلفون: Taiki Satoh, Marcelo A. S. Toledo, Janik Boehnke, Kathrin Olschok, Niclas Flosdorf, Katrin Götz, Caroline Küstermann, Stephanie Sontag, Kristin Seré, Steffen Koschmieder, Tim H. Brümmendorf, Nicolas Chatain, Yoh-ichi Tagawa, Martin Zenke
المصدر: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in cell and developmental biology 9, 1-11 (2021). doi:10.3389/fcell.2021.667304مصطلحات موضوعية: induced pluripotent stem cell, QH301-705.5, Biology, medicine.disease_cause, DC3, Proinflammatory cytokine, Cell and Developmental Biology, JAK2 V617F, Antigen, hemic and lymphatic diseases, medicine, dendritic cells, Biology (General), Induced pluripotent stem cell, Mutation, Chemistry, Cell Biology, Brief Research Report, hematopoiesis, In vitro, Cell biology, iPS cells, Haematopoiesis, JAK2, Stem cell, CD8, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8850827c7f56b4c9af738b8a4f5d3f72Test
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المؤلفون: Marcelo A. S. Toledo, Malrun Gatz, Stephanie Sontag, Karoline V. Gleixner, Gregor Eisenwort, Kristina Feldberg, Frederick Kluge, Riccardo Guareschi, Giulia Rossetti, Antonio S. Sechi, Olli M. J. Dufva, Satu M. Mustjoki, Angela Maurer, Herdit M. Schüler, Roman Goetzke, Till Braunschweig, Anne Simonowski, Jens Panse, Mohamad Jawhar, Andreas Reiter, Frank Hilberg, Peter Ettmayer, Wolfgang Wagner, Steffen Koschmieder, Tim H. Brümmendorf, Peter Valent, Nicolas Chatain, Martin Zenke
مصطلحات موضوعية: 0303 health sciences, Biology, Mast cell leukemia, medicine.disease, Embryonic stem cell, Receptor tyrosine kinase, 3. Good health, 03 medical and health sciences, Haematopoiesis, chemistry.chemical_compound, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Cancer research, medicine, biology.protein, Nintedanib, Systemic mastocytosis, Induced pluripotent stem cell, Tyrosine kinase, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6329305bf9f90e5d79d335b9a13bf9Test
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المؤلفون: Marcelo A. S. Toledo, Herdit M. Schüler, Janik Boehnke, Nicolas Chatain, Steffen Koschmieder, Tim H. Brümmendorf, Martin Zenke, Stephanie Sontag, Rafael Kramann, Salim Atakhanov
المصدر: Stem cell research 55, 102490 (2021). doi:10.1016/j.scr.2021.102490
Stem Cell Research, Vol 55, Iss, Pp 102490-(2021)مصطلحات موضوعية: Chemokine, QH301-705.5, Induced Pluripotent Stem Cells, medicine.disease_cause, JAK2 V617F, Exon, Polycythemia vera, hemic and lymphatic diseases, medicine, Humans, CRISPR, Biology (General), Induced pluripotent stem cell, Myelofibrosis, Polycythemia Vera, Mutation, biology, CXCL4, Cell Biology, General Medicine, Janus Kinase 2, medicine.disease, Hematopoiesis, iPS cells, PF4, Haematopoiesis, biology.protein, Cancer research, CRISPR-Cas Systems, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d357b9abf34fb99def172bd3fe26b4e9Test
https://doi.org/10.1016/j.scr.2021.102490Test -
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المؤلفون: Shivam Rai, Roman Goetzke, Marcelo A. S. Toledo, Julia Franzen, Martin Zenke, Joana Frobel, Wolfgang Wagner, Olivia Cypris, Stephanie Sontag
المصدر: Clinical Epigenetics
Clinical epigenetics 11(1), 19 (2019). doi:10.1186/s13148-019-0617-1
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-11 (2019)مصطلحات موضوعية: 0301 basic medicine, Stromal cell, lcsh:QH426-470, Induced Pluripotent Stem Cells, Mesenchymal stromal cells, lcsh:Medicine, Biology, Epigenesis, Genetic, Cell therapy, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Epigenetics, Induced pluripotent stem cell, Molecular Biology, Genetics (clinical), Cells, Cultured, Cell Proliferation, Hematopoietic differentiation, DNA methylation, Research, lcsh:R, Mesenchymal stem cell, dNaM, Epigenetic, Cell Differentiation, Mesenchymal Stem Cells, Hematopoietic Stem Cells, Coculture Techniques, Cell biology, Hematopoiesis, lcsh:Genetics, Haematopoiesis, 030104 developmental biology, 030220 oncology & carcinogenesis, Leukocyte Common Antigens, Stromal support, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866239cf7367e9310f8377ac3885e779Test
http://europepmc.org/articles/PMC6360658Test -
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المؤلفون: Martin Zenke, Kristin Seré, Malrun Förster, Stephanie Sontag
المصدر: Bio Protoc
مصطلحات موضوعية: 0301 basic medicine, Induced stem cells, Strategy and Management, Mechanical Engineering, Cellular differentiation, Metals and Alloys, Dendritic cell, Biology, Embryonic stem cell, Industrial and Manufacturing Engineering, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Methods Article, Stem cell, Induced pluripotent stem cell, Cell potency, Adult stem cell
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bf7dbf75ddd6830099fbb58addf99eTest
https://europepmc.org/articles/PMC8413509Test/ -
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المؤلفون: Paul Wanek, Herdit M. Schüler, Saskia Mitzka, Stefan Rose-John, Jie Qin, Kristin Seré, Martin Zenke, Steffen Koschmieder, Malrun Förster, Stephanie Sontag
المصدر: Stem cells 35(4), 898-908 (2017). doi:10.1002/stem.2565
مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Antigen presentation, Induced Pluripotent Stem Cells, Stem cell factor, Biology, Models, Biological, 03 medical and health sciences, Humans, Progenitor cell, Induced pluripotent stem cell, Cell Engineering, Cell Biology, Dendritic cell, Dendritic Cells, Embryonic stem cell, Cell biology, Hematopoiesis, 030104 developmental biology, Immunology, Interferon Regulatory Factors, Molecular Medicine, Stem cell, CRISPR-Cas Systems, Gene Deletion, Developmental Biology, Granulocytes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b376ca43543b1cdc6a20c8a46e6083dTest
https://publications.rwth-aachen.de/record/711061Test -
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المؤلفون: Nadina Ortiz-Brüchle, Claudia Schubert, Nicolas Chatain, Susanne Isfort, Steffen Koschmieder, Martin Kirschner, Karla Schmitt, Luisa Krüger, Mirle Schemionek, Klaus Zerres, Tim H. Brümmendorf, Martin Zenke, Stephanie Sontag
المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0123476 (2015)
PLOS ONE 10(4), e0123476 (2015). doi:10.1371/journal.pone.0123476مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Quality Control, Science, Single-nucleotide polymorphism, Biology, medicine.disease_cause, Polymorphism, Single Nucleotide, Frameshift mutation, chemistry.chemical_compound, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Humans, Alleles, Mutation, Multidisciplinary, ABL, Myeloproliferative Disorders, Genome, Human, Ponatinib, High-Throughput Nucleotide Sequencing, Amplicon, Janus Kinase 2, Molecular biology, chemistry, Bone marrow neoplasm, Medicine, ddc:500, Bone Marrow Neoplasms, Multiplex Polymerase Chain Reaction, Research Article, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a58319bfe6bcb9ad0598a77e011176Test
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المؤلفون: Qiong Lin, Michael Peitz, Isabelle Leisten, Robert Chunhua Zhao, Saskia Mitzka, Stephanie Sontag, Rebekka K. Schneider, Jie Qin, Anna Jauch, Martin Zenke, Oliver Brüstle, Xiaoying Wang, Wolfgang Wagner
المصدر: Stem cells and development. 23(23)
مصطلحات موضوعية: Cell fusion, animal structures, Cellular differentiation, Induced Pluripotent Stem Cells, Nodal signaling, Cell Differentiation, Cell Biology, Hematology, Anatomy, Biology, Hematopoietic Stem Cells, Embryonic stem cell, Antigens, Differentiation, Cell biology, Cell Fusion, Mesoderm, Haematopoiesis, Original Research Reports, embryonic structures, Humans, Stem cell, NODAL, Induced pluripotent stem cell, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e796b3065bb842df83a0687254786dTest
https://pubmed.ncbi.nlm.nih.gov/25004077Test