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المؤلفون: Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Sheena Pinto, Jens Pahl, Susanne Wingert, Joachim Koch, Björn Önfelt
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Pharmacology, Antibody-dependent cell-mediated cytotoxicity, Cancer Research, CD30, biology, Chemistry, medicine.drug_class, Immunology, Cell, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Monoclonal antibody, Immunological synapse, medicine.anatomical_structure, Cell killing, Oncology, medicine, Cancer research, biology.protein, Molecular Medicine, Immunology and Allergy, Cytotoxic T cell, Antibody, RC254-282
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b100f0a38751dbd8cb307946ee8d85Test
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adfTest -
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المؤلفون: Maki Nakayama, Maikel Luis Colli, Yann Verdier, Noemi Brusco, Lut Overbergh, Mark J. Mamula, Aïsha Callebaut, Joëlle Vinh, Guido Sebastiani, Georgia Afonso, Laura Nigi, Matthieu Giraud, Barbara Brandao, Zhicheng Zhou, Sylvaine You, Alexia Carré, Mijke Buitinga, Sheena Pinto, Marie Eliane Azoury, Decio L. Eizirik, Francesco Dotta, Chantal Mathieu, Søren Buus, Roberto Mallone, Fatoumata Samassa, Ana Ines Lalanne, Magali Irla
المساهمون: Spectrométrie de Masse Biologique et Protéomique (USR3149 / FRE2032) (SMBP), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)
المصدر: Diabetes
Diabetes, American Diabetes Association, 2021, pp.db210259. ⟨10.2337/db21-0259⟩مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Endocrinology, Diabetes and Metabolism, Citrullination, 030209 endocrinology & metabolism, Peptide, Biology, Molecular biology, Epitope, 03 medical and health sciences, 0302 clinical medicine, chemistry, PADI2, PADI4, Internal Medicine, Cytotoxic T cell, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, NOD mice
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a38375b241b82cebe35b607398e6eeaTest
https://doi.org/10.2337/figshare.16654669Test -
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المؤلفون: Joëlle Vinh, Aurore Pais, Sylvaine You, Etienne Larger, Decio L. Eizirik, Maikel Luis Colli, Laure Alexandre-Heymann, Danièle Dubois-Laforgue, Roberto Mallone, Søren Buus, Georgia Afonso, Graziella Bruno, Mahmoud Tarayrah, Cassandra Lavaud, Gonzalez-Duque Sergio, Jean-Paul Beressi, Sheena Pinto, Marie Eliane Azoury, Claire Maillard, Verdier Yann
المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Université libre de Bruxelles (ULB), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Spectrométrie de Masse Biologique et Protéomique (USR3149 / FRE2032) (SMBP), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), University of Copenhagen = Københavns Universitet (UCPH), Centre Hospitalier de Versailles André Mignot (CHV), Università degli studi di Torino = University of Turin (UNITO), YOU, Sylvaine, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université de Paris (UP), University of Copenhagen = Københavns Universitet (KU), University of Turin, Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Center for Diabetes Research and Welbio [Brussels, Belgium] (Medical Faculty), INSERM U1016, Institut Cochin, Paris, France
المصدر: Diabetes
Diabetes, 2020, 69 (12), pp.2678-2690. ⟨10.2337/db20-0013⟩
Diabetes, American Diabetes Association, 2020, 69 (12), pp.2678-2690. ⟨10.2337/db20-0013⟩مصطلحات موضوعية: 0301 basic medicine, biology, Effector, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], 030209 endocrinology & metabolism, Human leukocyte antigen, Nod, Epitope, Cell biology, [SDV] Life Sciences [q-bio], 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, MHC class I, Internal Medicine, biology.protein, Cytotoxic T cell, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, ComputingMilieux_MISCELLANEOUS, CD8, NOD mice
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1a19452588c10d10f72a2c18829d5eTest
https://www.hal.inserm.fr/inserm-03312401Test -
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المؤلفون: Christian Breunig, Savannah Jackson, Arndt Schottelius, Joachim Koch, Julia Knoch, Sheena Pinto
المصدر: Journal for ImmunoTherapy of Cancer. 9:A923-A923
مصطلحات موضوعية: Pharmacology, Antibody-dependent cell-mediated cytotoxicity, Cancer Research, Tumor microenvironment, Innate immune system, biology, Chemistry, medicine.drug_class, Immunology, Monoclonal antibody, Tumor antigen, Immune system, Oncology, medicine, biology.protein, Cancer research, Molecular Medicine, Immunology and Allergy, Macrophage, Antibody
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::0dda29f9474f9b70f79455870dec2fa0Test
https://doi.org/10.1136/jitc-2021-sitc2021.881Test -
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المؤلفون: Sheena Pinto, Bruno Kyewski, Benedikt Brors, Corey N. Miller, Chloé Michel, Rita Küchler, Mark S. Anderson
المصدر: The Journal of Immunology. 199:3488-3503
مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Cellular differentiation, Immunology, Cell, Apoptosis, Thymus Gland, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Agglutinin, Pregnancy, Lectins, medicine, Animals, Humans, Immunology and Allergy, Cell Lineage, Cells, Cultured, Mice, Knockout, Regulation of gene expression, MHC class II, biology, Histocompatibility Antigens Class II, FOXN1, Cell Differentiation, Epithelial Cells, Rats, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, biology.protein, Female, Biomarkers, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fefd1ab5ec945e00696024102c279fTest
https://doi.org/10.4049/jimmunol.1700203Test -
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المؤلفون: Bruno Kyewski, Sheena Pinto, Wolfgang Huber, Michelle Nguyen, Lars M. Steinmetz, Rita Küchler, Alejandro Reyes, Kristin Rattay, Philip Brennecke
المصدر: Nature immunology
مصطلحات موضوعية: Immunology, Autoimmunity, Thymus Gland, Biology, Autoantigens, Article, Mice, Single-cell analysis, Gene expression, Immunology and Allergy, Animals, Humans, RNA, Messenger, Gene, Regulation of gene expression, Genetics, Gene Expression Profiling, RNA, Epithelial Cells, Chromatin Assembly and Disassembly, Chromatin, Cell biology, Gene expression profiling, Self Tolerance, Gene Expression Regulation, Ectopic expression, Single-Cell Analysis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831e3424f869d132aa0b4c8e6fb34f21Test
http://europepmc.org/articles/PMC4675844Test -
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المؤلفون: Matthias Kuhn, Karen Cerosaletti, Anna Lissina, Georgia Afonso, Raphael Scharfmann, Jean-Paul Beressi, Etienne Larger, Francesco Dotta, Bruno Kyewski, Laura Nigi, Howard W. Davidson, Guido Sebastiani, David Price, Manuela Battaglia, Roberto Mallone, Søren Buus, Klaudia Kuranda, Sheena Pinto, Slobodan Culina, Ezio Bonifacio, James E. McLaren, Victor Appay, Ana Inés Lalanne, Thomas Osterbye, Kristin Ladell, Sophie Caillat-Zucman, Anne Eugster, Alicia Maugein
المساهمون: Mallone, Roberto, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Sorbonne Paris Cité (USPC), Université Paris Descartes - Paris 5 (UPD5), Translational Research Program [Seattle, WA, USA], Benaroya Research Institute [Seattle, WA, USA], Division of Developmental Immunology [Heidelberg, Germany], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Department of Medicine, Surgery and Neuroscience [Siena, Italy] (Diabetes Unit), University Hospital of Siena [Italy]-Fondazione Umberto di Mario ONLUS [Siena, Italy]-Toscana Life Sciences [Siena, Italy], CRTD-DFG Research Center for Regenerative Therapies Dresden [Dresden, Germany] (Medical Faculty), Technische Universität Dresden = Dresden University of Technology (TU Dresden), Department of Immunology and Microbiology [Copenhagen], Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Division of Infection and Immunity [Cardiff, UK] (School of Medicine), Cardiff University, Service de diabétologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Diabétologie [CH Versailles André Mignot, Le Chesnay], Centre Hospitalier de Versailles André Mignot (CHV), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Departement Hospitalo- Universitaire - Fight Ageing and STress [Paris] (DHU - FAST), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Barbara Davis Center for Childhood Diabetes (BDC), University of Colorado Anschutz [Aurora], Vaccine Research Center [Bethesda, MD, USA], National Institutes of Health [Bethesda] (NIH), Institut für Medizinische Informatik und Biometrie [Dresden, Germany] (Medical Faculty), Diabetes Research Institute [Milan, Italy], IRCCS Ospedale San Raffaele [Milan, Italy], Immunologie, génétique et traitement des maladies métaboliques et du diabète (UMR_S 561), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Jean Dausset d'Immunologie et d'Histocompatibilité [AP-HP Hôpital Saint-Louis], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], This work was performed within the Département Hospitalo-Universitaire AutHorS, supported by the Programme Hospitalier de Recherche Clinique ImMaDiab, Lilly France, the INSERM-Transfert Proof-of-Concept program acDC, the Ile-de-France CORDDIM, and grants from the JDRF (1-PNF-2014-155-A-V and 2-SRA-2016-164- Q-R), the Aviesan/Astra Zeneca 'Diabetes and the Vessel Wall Injury' program, the Société Francophone du Diabète, the Agence Nationale de la Recherche (ANR-2015-CE17-0018-01), the Fondation pour la Recherche Médicale (Equipe FRM DEQ20140329520), and the Helmsley Charitable Trust George S. Eisenbarth nPOD Award for Team Science (2015PG-T1D052) (to R.M.), a JDRF Biomarkers grant (17-2012-598) (to K.C.), an NIH R01 grant (DK052068) (to H.W.D.), Lilly and Fondation Bettencourt-Schueller funds (to R.S.), a European Research Council grant (ERC-2012-AdG) (to B.K.), and funds from JDRF, the Wellcome Trust, and the National Institute for Health Research Cambridge Biomedical Research Centre [to the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (Cambridge Institute for Medical Research, University of Cambridge), which provided PBMC samples from the JDRF D-GAP study]. Samples from at-risk patients were obtained through a TrialNet ancillary study to the TN-01 Pathway to Prevention study funded by NIH grants U01 DK061010, U01 DK061034, U01 DK061042, U01 DK061058, U01 DK085465, U01 DK085453, U01 DK085461, U01 DK085463, U01 DK085466, U01 DK085499, U01 DK085504, U01 DK085505, U01 DK085509, U01 DK103180, U01- DK103153, U01-DK085476, and U01-DK103266 and by JDRF. D.A.P. is a Wellcome Trust Senior Investigator (100326Z/12/Z). This research was performed with the support of the nPOD, a collaborative T1D research project funded by JDRF. Organ procurement organizations partnering with nPOD to provide research resources are listed at www.jdrfnpod.org/ for-partners/npod-partners/. This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (INNODIA, no. 115797). This Joint Undertaking receives support from the Union’s Horizon 2020 research and innovation program and the European Federation of Pharmaceutical Industries and Associations, JDRF, and the Leona M. and Harry B. Helmsley Charitable Trust., Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Institutes of Health [Bethesda] (NIH)-National Institutes of Health, Bethesda
المصدر: Science Immunology
Science Immunology, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩
Science Immunology, American Association for the Advancement of Science, 2018, 3 (20), ⟨10.1126/sciimmunol.aao4013⟩مصطلحات موضوعية: 0301 basic medicine, geography, endocrine system, geography.geographical_feature_category, endocrine system diseases, [SDV.IMM] Life Sciences [q-bio]/Immunology, T cell, Immunology, General Medicine, Biology, Islet, Epitope, 3. Good health, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Antigen, Cell culture, Interferon, medicine, Cytotoxic T cell, [SDV.IMM]Life Sciences [q-bio]/Immunology, CD8, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a7fec2e9c93b9cae858cfe4689cdaTest
https://www.hal.inserm.fr/inserm-01918833/documentTest -
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المؤلفون: Meinrad Busslinger, Esther Lutgens, Norbert Gerdes, Tomoyoshi Yamano, Jelena Nedjic, Benedikt Brors, Madlen Steinert, Maria Hinterberger, Sheena Pinto, Naozumi Ishimaru, Sandra D Koser, Bruno Kyewski, Ludger Klein
المساهمون: Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity
المصدر: Immunity, 42(6), 1048-1061. Cell Press
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Immunology, Context (language use), Thymus Gland, Biology, Autoantigens, Mice, Negative selection, Downregulation and upregulation, Animals, Humans, Immunology and Allergy, CD40 Antigens, Clonal Selection, Antigen-Mediated, Antigen-presenting cell, Cells, Cultured, Mice, Knockout, Antigen Presentation, B-Lymphocytes, Mice, Inbred BALB C, Repertoire, Histocompatibility Antigens Class II, Cell Differentiation, Central T-cell tolerance induction, Immunoglobulin Class Switching, Cell biology, Infectious Diseases, Central Tolerance, B7-1 Antigen, Central tolerance, CD80, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a56a3afa14eff3431ef68e94209df0Test
https://doi.org/10.1016/j.immuni.2015.05.013Test -
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المؤلفون: Thomas Blankenstein, Bruno Kyewski, Sheena Pinto, Dolores J. Schendel, Wolfgang Uckert, Susanne Wilde, Daniel Sommermeyer, Chloé Michel
المصدر: European Journal of Immunology. 44:2811-2821
مصطلحات موضوعية: integumentary system, Immunology, T-cell receptor, Biology, Molecular biology, Epitope, Interleukin 21, Antigen, Transcription (biology), Immunology and Allergy, Cytotoxic T cell, Central tolerance, neoplasms, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::3a44a0ba76d9fb411e37f23443bd8ff6Test
https://doi.org/10.1002/eji.201444499Test -
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المؤلفون: Tim Holland-Letz, Bruno Kyewski, Fabian Brunk, Alla Slynko, Sheena Pinto, Chloé Michel, Annette Kopp-Schneider
المصدر: European journal of immunology. 47(7)
مصطلحات موضوعية: 0301 basic medicine, Stromal cell, TEC, Cellular differentiation, education, Immunology, Genes, MHC Class II, Gene Expression, chemical and pharmacologic phenomena, Thymus Gland, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Organ Culture Techniques, Immunology and Allergy, Animals, Cell Lineage, Progenitor cell, Cells, Cultured, MHC class II, Thymocytes, biology, hemic and immune systems, Epithelial cell adhesion molecule, Cell Differentiation, Epithelial Cells, Models, Theoretical, Epithelial Cell Adhesion Molecule, Embryonic stem cell, Cell biology, 030104 developmental biology, chemistry, biology.protein, B7-1 Antigen, Leukocyte Common Antigens, Stem cell, tissues, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b44088e36672097a7582b0b9f3fb2c7Test
https://pubmed.ncbi.nlm.nih.gov/28439878Test