نتائج البحث - "Sequestosome-1"

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nat. Commun. 11:2306 (2020)
Nature Communications
Fischer, K, Fenzl, A, Liu, D, Dyar, K A, Kleinert, M, Brielmeier, M, Clemmensen, C, Fedl, A, Finan, B, Gessner, A, Jastroch, M, Huang, J, Keipert, S, Klingenspor, M, Brüning, J C, Kneilling, M, Maier, F C, Othman, A E, Pichler, B J, Pramme-Steinwachs, I, Sachs, S, Scheideler, A, Thaiss, W M, Uhlenhaut, H, Ussar, S, Woods, S C, Zorn, J, Stemmer, K, Collins, S, Diaz-Meco, M, Moscat, J, Tschöp, M H & Müller, T D 2020, ' The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation ', Nature Communications, vol. 11, no. 1, 2306 . https://doi.org/10.1038/s41467-020-16230-8Test

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Male, Transcriptional regulatory elements, Metabolic disorders, General Physics and Astronomy, Adipose tissue, p38 Mitogen-Activated Protein Kinases, Mice, 0302 clinical medicine, Adipose Tissue, Brown, Positron Emission Tomography Computed Tomography, Brown adipose tissue, Sequestosome-1 Protein, lcsh:Science, Uncoupling Protein 1, Mice, Knockout, Multidisciplinary, Adipogenesis, biology, Chemistry, Magnetic Resonance Imaging, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Activating transcription factor 2, Cell biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Phosphorylation, Protein Binding, Adipose Tissue, White, Science, Alpha (ethology), General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, ddc:570, medicine, Animals, ddc:610, Obesity, Enhancer, Cell Nucleus, Activating Transcription Factor 2, General Chemistry, Mice, Inbred C57BL, 030104 developmental biology, biology.protein, lcsh:Q, Thermogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc1314eb5ff4321d5e23f918f17181fTest
http://link.springer.com/article/10.1038/s41467-020-16230-8Test

37

Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases

المؤلفون: Cara J. Riffe, Benoit I. Giasson, Anthony T. Yachnis, Zachary A. Sorrentino, Jorge A. Trejo-Lopez, Stefan Prokop, Dennis W. Dickson

المصدر: J Neuropathol Exp Neurol

مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, medicine.drug_class, tau Proteins, Biology, Monoclonal antibody, Pathology and Forensic Medicine, Progressive supranuclear palsy, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Sequestosome 1, Sequestosome-1 Protein, medicine, Neuropil, Animals, Humans, education, Cells, Cultured, Aged, 030304 developmental biology, Aged, 80 and over, Inclusion Bodies, Mice, Inbred BALB C, 0303 health sciences, education.field_of_study, Antibodies, Monoclonal, Neurodegenerative Diseases, Original Articles, General Medicine, Middle Aged, medicine.disease, Immunohistochemistry, medicine.anatomical_structure, Neurology, Polyclonal antibodies, Astrocytes, Monoclonal, alpha-Synuclein, biology.protein, Female, Neurology (clinical), Alzheimer's disease, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8ad608cc73aa1bf40129353a6a3590Test
https://doi.org/10.1093/jnen/nlaa007Test

38

Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk

المؤلفون: João F. Passos, Anthony B. Lagnado, Elizabeth J. Soilleux, Katerina Pyrillou, Rebecca Brais, Nicholas T. Ktistakis, Liam D. Cassidy, Diana Jurk, Bettina M. Weigand, Masashi Narita, Murray C.H. Clarke, Kimberley A. Wiggins, Edward Fielder, Andrew R. J. Young, Christopher N. J. Young

المساهمون: Cassidy, Liam D [0000-0002-9312-6256], Young, Christopher N J [0000-0001-7512-8971], Pyrillou, Katerina [0000-0003-0375-7810], Jurk, Diana [0000-0003-4486-0857], Narita, Masashi [0000-0001-7764-577X], Apollo - University of Cambridge Repository, Cassidy, Liam D. [0000-0002-9312-6256], Young, Christopher N. J. [0000-0001-7512-8971], Young, Christopher NJ [0000-0001-7512-8971]

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, General Physics and Astronomy, Autophagy-Related Protein 5, Mice, 0302 clinical medicine, Neoplasms, Sequestosome-1 Protein, 692/308/1426, lcsh:Science, 13/89, Bone Marrow Transplantation, Skin, Cancer, Mice, Knockout, Multidisciplinary, Muscles, article, Phenotype, 3. Good health, Experimental models of disease, 631/80/39/2346, 030220 oncology & carcinogenesis, Muscle, Female, 64/60, ATG5, medicine.symptom, 631/67, Science, Longevity, Inflammation, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 13/21, Macroautophagy, medicine, Autophagy, Animals, General Chemistry, medicine.disease, Mice, Inbred C57BL, Ageing, Disease Models, Animal, 030104 developmental biology, 13/51, Cancer research, lcsh:Q, Cancer risk

وصف الملف: application/pdf; text/xml; application/zip

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678fc7a70f3aa7a42256be1e52835df0Test
http://link.springer.com/article/10.1038/s41467-019-14187-xTest

39

Activation of cannabinoid receptor type 2-induced osteogenic differentiation involves autophagy induction and p62-mediated Nrf2 deactivation

المؤلفون: Yang Yang, Yang Shao, Ai-Hua Xu, Yong-Xin Sun, Meng Wu

المصدر: Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Cell Communication and Signaling : CCS

مصطلحات موضوعية: 0301 basic medicine, Nrf2 signaling pathway, NF-E2-Related Factor 2, lcsh:Medicine, Biochemistry, Cell Line, Receptor, Cannabinoid, CB2, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Osteogenesis, Sequestosome-1 Protein, Cannabinoid receptor type 2, medicine, Autophagy, Humans, Osteopontin, lcsh:QH573-671, Molecular Biology, Cell Nucleus, Kelch-Like ECH-Associated Protein 1, biology, Protein Stability, Chemistry, lcsh:Cytology, Research, Adenine, TOR Serine-Threonine Kinases, Osteoblast, CNR2, Mesenchymal stem cell, p62, lcsh:R, Cell Differentiation, Cell Biology, Endocannabinoid system, Cell biology, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Proteolysis, Osteocalcin, biology.protein, Osteoporosis, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dfa0e61c796a73d4462e9bb7e384bcTest
https://doaj.org/article/74ead13b79414773bc051009d14bc4fbTest

40

Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1‐dependent mitophagy in a Salmonella infantis model of piglet diarrhea

المؤلفون: Mei-Jun Wang, Jin-Hui Su, Bing Xia, Yao-Hong Zhu, Jiu-Feng Wang, Jiao Yu, Xiao Liu, Ting He

المصدر: The FASEB Journal. 34:2821-2839

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56eed32fb518fb8a2ab8a0b73d2cfc8Test
https://doi.org/10.1096/fj.201901445rrrTest

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