نتائج البحث

1

Analysis of morphological and neurochemical changes in subthalamic nucleus neurons in response to a unilateral 6-OHDA lesion of the substantia nigra in adult rats

المؤلفون: Andrew L. Gundlach, David Finkelstein, Katayoun Sedaghat

المصدر: IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 96-103 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18be20b9c24d5da4cf8deb58f25c6be9Test
https://doi.org/10.1016/j.ibneur.2021.01.002Test

2

β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins

المؤلفون: Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Kirill D. Chaprov, Holger B. Kramer, Dominic J. Withers, Arthur T. Kopylov, Vladimir L. Buchman, Steven Millership, Alex Montoya

المساهمون: Wellcome Trust ISSF Funding, Medical Research Council

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: MPTP toxicity, MPP+, 1-methyl-4-phenylpyridinium, animal diseases, Parkinson's disease, Dopamine, Vesicular monoamine transporter 2, Biochemistry, chemistry.chemical_compound, Mice, neurodegenerative disease, synapse, DAT, dopamine transporter, Synuclein Family, 11 Medical and Health Sciences, Mice, Knockout, vesicles, biology, Cell Death, MPTP, CLIP, crosslink immunoprecipitation, Dopaminergic, LFQ, label-free quantitation, PSM, peptide-spectrum match, Cell biology, SNpc, substantia nigra pars compacta, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, iBAQ, intensity-based absolute quantification, Synaptic Vesicles, 03 Chemical Sciences, TKO, triple α/β/γ-synuclein null mutant mice, Research Article, Biochemistry & Molecular Biology, FDR, false discovery rate, TH, tyrosine hydroxylase, MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Substantia nigra, transgenic mice, Synaptic vesicle, synuclein, beta-Synuclein, mental disorders, GO, Gene Ontology, Animals, Molecular Biology, AADC, aromatic l-amino acid decarboxylase, neurotransmitter vesicular uptake, dopaminergic neurons, Pars compacta, Cell Biology, 06 Biological Sciences, nervous system diseases, Vesicular monoamine transporter, chemistry, nervous system, VMAT-2, vesicular monoamine transporter 2, biology.protein, Parkinson’s disease, DTSSP, 3,3′-dithiobis(sulfosuccinimidylpropionate)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c25bdcdb04d42ed3e6e25fe31cef99Test
http://europepmc.org/articles/PMC8633583Test

3

Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of Neuropsin in an MPTP-Induced Mouse Model of Parkinson’s Disease

المؤلفون: Motohiro Kaya, Tetsuya Kuhara, Hidefumi Furuoka, Toshiaki Ishii

المصدر: Biomedicines
Volume 9
Issue 2
Biomedicines, Vol 9, Iss 167, p 167 (2021)

مصطلحات موضوعية: medicine.medical_specialty, Parkinson's disease, hippocampus, ved/biology.organism_classification_rank.species, Central nervous system, synaptophysin (SYP), Medicine (miscellaneous), Hippocampus, Hippocampal formation, spine, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Internal medicine, postsynaptic density protein-95 (PSD95), medicine, lcsh:QH301-705.5, MPTP, neuropsin, Bifidobacterium breve, biology, ved/biology, business.industry, substantia nigra pars compacta (SNpc), memory extinction, medicine.disease, Endocrinology, medicine.anatomical_structure, chemistry, lcsh:Biology (General), Synaptophysin, biology.protein, Parkinson’s disease, dopamine, business, Postsynaptic density, Bifidobacterium breve strain A1 [MCC1274] (B. breve A1)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641c54fb5d20754d076606adeba6ee7bTest

4

CaV1.3 L-Type Calcium Channels Increase the Vulnerability of Substantia Nigra Dopaminergic Neurons in MPTP Mouse Model of Parkinson’s Disease

المؤلفون: Aditi Verma, Vijayalakshmi Ravindranath

المصدر: Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Aging, Cognitive Neuroscience, Substantia nigra, Cav1.3, lcsh:RC321-571, 03 medical and health sciences, chemistry.chemical_compound, alternative splicing, 0302 clinical medicine, Internal medicine, medicine, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, MPTP, biology, Tyrosine hydroxylase, Pars compacta, Calcium channel, Neurodegeneration, neurodegeneration, Brief Research Report, medicine.disease, SNpc, Ventral tegmental area, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, nervous system, biology.protein, gene expression, CaV1.342A, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6196850009f31c46784614b4a1ace977Test

5

Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model

المؤلفون: Liyan Hou, Wei Sun, Fuqiang Sun, Ruixue Huang, Dan Zhang, Qingshan Wang

المصدر: Redox Biology, Vol 22, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, Nonmotor symptoms, Clinical Biochemistry, MPO, myeloperoxidase, Pharmacology, medicine.disease_cause, Biochemistry, PD, Parkinson's disease, Hippocampus, P + M, paraquat and maneb, chemistry.chemical_compound, Mice, 0302 clinical medicine, Paraquat, Neuroinflammation, Enzyme Inhibitors, lcsh:QH301-705.5, Cerebral Cortex, lcsh:R5-920, NADPH oxidase, biology, Behavior, Animal, Cognitive deficits, Neurodegeneration, NF-kappa B, Parkinson Disease, SNpc, substantia nigra pars compacta, Mitochondria, TNFα, tumor necrosis factor α, STAT1 Transcription Factor, MWM, morris maze test, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Microglia, lcsh:Medicine (General), STAT1, signal transducers and activators of transcription 1, Research Paper, inorganic chemicals, TH, tyrosine hydroxylase, Iba-1, ionized calcium binding adaptor molecule-1, NF-κB, nuclear factor-κB, 03 medical and health sciences, ROS, reactive oxygen species, Memory, SOD, superoxide dismutase, medicine, Animals, Learning, MDA, malondialdehyde, Tyrosine hydroxylase, AD, Alzheimer disease, Dopaminergic Neurons, Organic Chemistry, Acetophenones, NADPH Oxidases, medicine.disease, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, chemistry, lcsh:Biology (General), Apocynin, biology.protein, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0d2a312a701be8ce2761d13e178115Test
http://www.sciencedirect.com/science/article/pii/S2213231719300291Test

6

Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption

المؤلفون: Pamela Lopert, Manisha Patel

المصدر: Redox Biology
Redox Biology, Vol 2, Iss C, Pp 667-672 (2014)

مصطلحات موضوعية: Male, DJ-1, PQ, paraquat, GSH, reduced glutathione, Thioredoxin reductase, Clinical Biochemistry, Glutathione reductase, Cox IV, complex IV, Protein Deglycase DJ-1, Mitochondrion, ASK1, apoptosis signal-regulating kinase 1, Biochemistry, TrxR2, mitochondrial Trx, chemistry.chemical_compound, Mice, Thioredoxins, Glutaredoxin, Trx, thioredoxin, GR, glutathione reductase, Trx1, cytosolic trx, GRX, glutaredoxin, lcsh:QH301-705.5, HEDS, 2-hydroxyethyl disulfide, chemistry.chemical_classification, Mice, Knockout, Oncogene Proteins, lcsh:R5-920, 4-HNE, 4-hydroxyl-2-nonenal, GSSG, oxidized glutathione, DA, dopaminergic, Brain, Glutathione, 6OHDA, 6-hydroxydopamine, Mitochondria, SNpc, substantia nigra pars compacta, Glutathione Reductase, Nrf2, nuclear factor erythroid 2-related factor, H2O2, hydrogen peroxide, BSA, Bovin Serum Albumin, Thioredoxin, lcsh:Medicine (General), Research Paper, TrxR, thioredoxin reductase, Thioredoxin-Disulfide Reductase, TH, tyrosine hydroxylase, MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Biology, ROS, reactive oxygen species, Gpx, glutathione peroxidase, Animals, Glutaredoxins, PD, Parkinson’s disease, MEF, mouse embryonic fibroblasts, Reactive oxygen species, Trx2, mitochondrial trx, Glutathione Peroxidase, Organic Chemistry, Hydrogen Peroxide, Peroxiredoxins, Molecular biology, chemistry, lcsh:Biology (General), TrxR1, cytosolic TrxR, Oxidative stress, DJ1-/-, DJ-1 knockout, Parkinson’s disease, Glutathione disulfide, Prx, peroxiredoxin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a1a94e2d749607bdffffb692abaf3fTest
http://europepmc.org/articles/PMC4052521Test

7

ELECTROPHYSIOLOGICAL AND AMPEROMETRIC EVIDENCE THAT MODAFINIL BLOCKS THE DOPAMINE UPTAKE TRANSPORTER TO INDUCE BEHAVIORAL ACTIVATION

المؤلفون: Emanuele Claudio Latagliata, Robert Nisticò, Howard H. Gu, Ada Ledonne, Stefano Puglisi-Allegra, Mauro Federici, Nicola Biagio Mercuri, Francesca Romana Rizzo, Andrea Romigi

مصطلحات موضوعية: Patch-Clamp Techniques, Dopamine Plasma Membrane Transport Proteins, Animals, SNpc, dopamine overflow, Benzhydryl Compounds, aCSF, dopamine transporter, Wakefulness-Promoting Agents, Dopamine, locomotor activation, constant potential amperometry, Cocaine, amperometry, DAT, substantia nigra pars compacta, Brain, Mice, i.p, Dopaminergic Neurons, intraperitoneally, Mice, Mutant Strains, artificial cerebrospinal fluid, modafinil, Motor Activity, CPA, dat, Substantia nigra, Striatum, Pharmacology, mental disorders, medicine, Dopamine transporter, biology, Chemistry, Pars compacta, General Neuroscience, Dopaminergic, Modafinil, Settore BIO/14, Mutant Strains, nervous system, biology.protein, Neuroscience, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4299c379e36dbb20b5892cf7f878cc9Test
http://hdl.handle.net/11573/556084Test

8

7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease

المؤلفون: José Enrique Yuste, A. Gómez, Emiliano Fernández-Villalba, M. B. Echeverry, Maria Herrero, Francisco Ros-Bernal, Carmen María Campuzano, Carmen María Brugarolas Ros

المصدر: Repositori Universitat Jaume I
Universitat Jaume I

مصطلحات موضوعية: Male, medicine.medical_specialty, Dopamine and cAMP-Regulated Phosphoprotein 32, 7-Nitroindazole, Indazoles, Dopamine, Nigrostriatal pathway, nNOS, Substantia nigra, Striatum, Nitric Oxide Synthase Type I, 6-OHDA, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Internal medicine, medicine, Animals, Enzyme Inhibitors, Parkinson Disease, Secondary, Phosphorylation, Oxidopamine, Pharmacology, Neurons, biology, Pars compacta, Dorsolateral, Rats, SNpc, DARPP-32, Nitric oxide synthase, Neostriatum, Disease Models, Animal, 7-NI, medicine.anatomical_structure, Endocrinology, chemistry, nervous system, EBST, biology.protein, TH, Neuroscience, medicine.drug, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652474b56915c03ad32d25885e9fad27Test

9

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

المؤلفون: Radha Goh Nair-Roberts, Helen White-Cooper, Elizabeth Benson, Mark A. Ungless, S. D. Chatelain-Badie, J. P. Bolam

المصدر: Neuroscience

مصطلحات موضوعية: Male, RT-PCR, reverse transcriptase–polymerase chain reaction, Dopamine, IP, interpeduncular nucleus, lSN, lateral substantia nigra, Cell Count, PBS-T, phosphate-buffered saline containing 0.1% Tween 20, Rats, Sprague-Dawley, Stereotaxic Techniques, RLi, rostral linear nucleus, Mesencephalon, Basal ganglia, Tegmentum, gamma-Aminobutyric Acid, reward, HB, hybridization buffer, Neurons, GAD, glutamic acid decarboxylase, Glutamate Decarboxylase, General Neuroscience, GAD, Dopaminergic, SNpc, substantia nigra pars compacta, Ventral tegmental area, Substantia Nigra, RRF, retrorubral field, medicine.anatomical_structure, basal ganglia, SN, substantia nigra, medicine.drug, PBP, parabrachial nucleus, Tyrosine 3-Monooxygenase, Neuroscience(all), TH, tyrosine hydroxylase, PBS, phosphate-buffered saline, Glutamic Acid, vSN, ventral substantia nigra, Substantia nigra, midbrain, VGluT, vesicular glutamate transporter, Biology, Medium spiny neuron, VTA, ventral tegmental area, PN, paranigral nucleus, VGluT2, medicine, Animals, RNA, Messenger, IFN, interfascicular subnucleus of the ventral tegmental area, Pars compacta, Ventral Tegmental Area, Rats, Neuroanatomy, nervous system, Vesicular Glutamate Transport Protein 2, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0557dc4d7d3bb241739c2af10a37e66Test
http://ora.ox.ac.uk/objects/uuid:fe5b4b78-c6a9-4f83-9d93-c2aba5adb40bTest

تنقيح النتائج