نتائج البحث - "Rinath Jeselsohn"

1

Restoring order at the cell cycle border: Co-targeting CDK4/6 and CDK2

المؤلفون: Rachel Schiff, Albert Grinshpun, Rinath Jeselsohn

المصدر: Cancer Cell. 39:1302-1305

مصطلحات موضوعية: Cancer Research, Cell Cycle, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 4, Biology, Cell cycle, Oncology, Proto-Oncogene Proteins, Cancer cell, Cancer research, biology.protein, biological phenomena, cell phenomena, and immunity, Protein Kinase Inhibitors, Cyclin-Dependent Kinase Inhibitor p27, Cyclin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834b500b05ce7841cbc907ecedcc3e03Test
https://doi.org/10.1016/j.ccell.2021.08.007Test

2

Abstract GS1-07: Treatment persistence of residual breast tumors through an embryonic diapause-like cancer cell state with suppressed myc activity

المؤلفون: Eugen Dhimolea, Michal Sheffer, Constantine S. Mitsiades, Myles Brown, Ricardo De Matos Simoes, Juliette Bouyssou, Aedín C. Culhane, Jennifer Roth, Nathanael S. Gray, Dhvanir Kansara, Rinath Jeselsohn, Boris Bartholdy, Ulrich Steidl

المصدر: Cancer Research. 81:GS1-07

مصطلحات موضوعية: Cancer Research, BRD4, Cancer, Biology, medicine.disease, Embryonic stem cell, Breast cancer, Oncology, Cancer cell, Cancer research, Organoid, medicine, Cytotoxic T cell, Reprogramming

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5543f5ef938bdec2c527c495f5df2cf4Test
https://doi.org/10.1158/1538-7445.sabcs20-gs1-07Test

3

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

المساهمون: De Angelis, C., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., Hilsenbeck, S. G., Benelli, M., Migliaccio, I., Guarducci, C., Malorni, L., Litchfield, L. M., Liu, J., Donaldson, J., Selenica, P., Brown, D. N., Weigelt, B., Reis-Filho, J. S., Park, B. H., Hurvitz, S. A., Slamon, D. J., Rimawi, M. F., Jansen, V. M., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pyridines, Oncology and Carcinogenesis, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, Receptors, Breast Cancer, Genetics, Tumor Cells, Cultured, Humans, Medicine, Oncology & Carcinogenesis, Cancer, Cultured, biology, business.industry, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Estrogen, Immune checkpoint, Tumor Cells, Good Health and Well Being, 030104 developmental biology, Receptors, Estrogen, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Cyclin-dependent kinase 6, Development of treatments and therapeutic interventions, Signal transduction, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d5dea84c01cc54303c5f5ebf7c4dcTest
https://doi.org/10.1158/1078-0432.ccr-19-4191Test

4

The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor

المؤلفون: Rachid Safi, Suzanne E. Wardell, Kaitlyn Andreano, Steffi Oesterreich, Ching-Yi Chang, Donald P. McDonnell, Sunghee Park, Myles Brown, Sarah Sammons, Sandeep Artham, John D. Norris, Jennifer G. Baker, Rinath Jeselsohn

المصدر: Molecular Cancer Therapeutics. 19:1395-1405

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8c70e648999333673bd4e6986eab1ff9Test
https://doi.org/10.1158/1535-7163.mct-19-1148Test

5

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

المساهمون: Fu, X., Pereira, R., De Angelis, C., Veeraraghavan, J., Nanda, S., Qin, L., Cataldo, M. L., Sethunath, V., Mehravaran, S., Gutierrez, C., Chamness, G. C., Feng, Q., O'Malley, B. W., Selenica, P., Weigelt, B., Reis-Filho, J. S., Cohen, O., Wagle, N., Nardone, A., Jeselsohn, R., Brown, M., Rimawi, M. F., Osborne, C. K., Schiff, R.

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Multidisciplinary, Chromatin binding, Pioneer factor, Enhancer/transcriptional reprogramming, Biological Sciences, Biology, medicine.disease, Metastatic breast cancer, Metastasis, Breast cancer, Cancer research, medicine, FOXA1, Transcription factor, Reprogramming, Endocrine resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524cedf1e32bed7312ca09dcdb1188ecTest
https://doi.org/10.1073/pnas.1911584116Test

6

Temporal and spatial topography of cell proliferation in cancer

المؤلفون: Deborah A. Dillon, Sandro Santagata, Shu Wang, Peter K. Sorger, Shannon Coy, Jean J. Zhao, Danae Argyropoulou, Yang Dai, Sheheryar Kabraji, Otto Metzger, Eric P. Winer, Rinath Jeselsohn, Jia-Ren Lin, Giorgio Gaglia, Johann Bergholz

مصطلحات موضوعية: Immune system, Oncogene, Cell growth, Tissue imaging, Cancer cell, medicine, Cancer, Coherence (statistics), Biology, Cell cycle, medicine.disease, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bf41e1080712d2aa583d7999e2487f73Test
https://doi.org/10.1101/2021.05.16.443704Test

7

Abstract PD7-12: Inhibition of CDK7 overcomes resistance to CDK4/6 inhibitors in hormone receptor positive breast cancer cells

المؤلفون: Myles Brown, Antonio Nardone, A. Di Leo, Luca Malorni, C. Guarducci, Rinath Jeselsohn, I. Migliaccio, Geoffrey I. Shapiro, Martina Bonechi, A Feiglin, M. Benelli, G Hodgson

المصدر: Cancer Research. 79:PD7-12

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::83ed4d202ffa416c74009cddb10ca97fTest
https://doi.org/10.1158/1538-7445.sabcs18-pd7-12Test

8

An embryonic diapause-like adaptation with suppressed Myc activity enables tumor treatment persistence

المصدر: Cancer Cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27960f6b5655eb355223383013aae78cTest
https://europepmc.org/articles/PMC8670073Test/

9

The ESR1 Mutations: From Bedside to Bench to Bedside

المؤلفون: Francisco Hermida-Prado, Rinath Jeselsohn

المصدر: Cancer Research. 81:537-538

مصطلحات موضوعية: 0301 basic medicine, Genetics, Cancer Research, biology, Mechanism (biology), Estrogen receptor, Bench to bedside, body regions, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Acquired resistance, Oncology, 030220 oncology & carcinogenesis, biology.protein, CRISPR, Aromatase, Estrogen receptor alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ba0961167ad0e8d28c2eb2d27a0a7c9dTest
https://doi.org/10.1158/0008-5472.can-20-4037Test

10

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

المساهمون: Fassl, A., Brain, C., Abu-Remaileh, M., Stukan, I., Butter, D., Stepien, P., Feit, A. S., Bergholz, J., Michowski, W., Otto, T., Sheng, Q., Loo, A., Michael, W., Tiedt, R., De Angelis, C., Schiff, R., Jiang, B., Jovanovic, B., Nowak, K., Ericsson, M., Cameron, M., Gray, N., Dillon, D., Zhao, J. J., Sabatini, D. M., Jeselsohn, R., Brown, M., Polyak, K., Sicinski, P.

المصدر: Science Advances

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4815f131efc64eea3d77fec1fe579fTest
http://hdl.handle.net/11588/857297Test

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