المؤلفون: Moammer, Hussam, Bai, Jizhong, Jones, Timothy LM, Ward, Marie, Barrett, Caroyln, Crossman, David J

مصطلحات موضوعية: fibrosis, heart failure, myocardial infarction, pirfenidone, transverse tubules, 3208 Medical Physiology, 32 Biomedical and Clinical Sciences, Heart Disease, Cardiovascular, Heart Disease - Coronary Heart Disease, Science & Technology, Life Sciences & Biomedicine, Biology, Life Sciences & Biomedicine - Other Topics, HEART-FAILURE, VENTRICULAR MYOCYTES, T-TUBULES, INTERSTITIAL FIBROSIS, REDUCED SYNCHRONY, FAILING HUMAN, CA2+ RELEASE, IMPACT

جغرافية الموضوع: England

وصف الملف: Electronic-eCollection; application/pdf

العلاقة: Interface focus; (2023). Interface Focus, 13(6), 20230047-.; https://hdl.handle.net/2292/67604Test; 38106917 (pubmed); rsfs20230047

الإتاحة: https://doi.org/10.1098/rsfs.2023.0047Test
https://hdl.handle.net/2292/67604Test

المؤلفون: Sandhya Kadamboor Veethil, Seyed Hootan Hamidi, Seyedeh Harir Hamidi

المصدر: Pharmacological Reports

مصطلحات موضوعية: Epithelial sodium channel, Pyridones, Pathology of COVID-19, Inflammation, Review, Pharmacology, Lung injury, medicine.disease_cause, TGF-β signaling, SARS-CoV-2 mechanism, chemistry.chemical_compound, Transforming Growth Factor beta, Medicine, Humans, Coronavirus, biology, business.industry, SARS-CoV-2, Anti-Inflammatory Agents, Non-Steroidal, Pirfenidone mechanism of action, COVID-19, General Medicine, Pirfenidone, Lung Injury, Cystic fibrosis transmembrane conductance regulator, COVID-19 Drug Treatment, chemistry, Plasminogen activator inhibitor-1, biology.protein, COVID-19 therapy, medicine.symptom, business, Transforming growth factor, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c57b2f218e93b6faa6abde85e9a200Test
http://europepmc.org/articles/PMC8057922Test

المؤلفون: C. Alejandra Monraz-Méndez, Rebeca Escutia-Gutiérrez, Ana Sandoval-Rodriguez, Juan Armendáriz-Borunda, Arturo Santos-Garcia, J. Samael Rodríguez-Sanabria, Jesús García-Bañuelos

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Pyridones, Science, Inflammation, Biology, Article, Collagen Type I, Transcriptome, 03 medical and health sciences, Mice, 0302 clinical medicine, Insulin resistance, Liver Function Tests, Non-alcoholic Fatty Liver Disease, Internal medicine, microRNA, medicine, Animals, Lipid Metabolic Process, Liver diseases, Non-alcoholic steatohepatitis, Multidisciplinary, Hepatology, Fatty liver, Gastroenterology, Lipid metabolism, Pirfenidone, medicine.disease, Lipid Metabolism, Immunohistochemistry, Fatty Liver, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Cytokines, Medicine, 030211 gastroenterology & hepatology, Disease Susceptibility, medicine.symptom, Inflammation Mediators, Biomarkers, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f995af61f22c62a8c498cfcc372d922Test
https://doaj.org/article/3d0a5ea6aa3f4130aece7fe0791813bcTest

المؤلفون: Lisa Allamassey, Eric Helmer, Julie Desrivot, Tim Van Kaem

المصدر: Clinical Pharmacology in Drug Development

مصطلحات موضوعية: Adult, Male, cytochrome P450, Metabolite, Pharmaceutical Science, Original Manuscript, CYP2C19, GLPG1205, Pharmacology, 030226 pharmacology & pharmacy, Receptors, G-Protein-Coupled, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, drug‐drug interaction, Double-Blind Method, Cytochrome P-450 CYP1A2, medicine, Humans, Pharmacology (medical), Drug Interactions, Cytochrome P-450 CYP2C9, Cross-Over Studies, biology, business.industry, CYP1A2, Cytochrome P450, Pirfenidone, Articles, Middle Aged, idiopathic pulmonary fibrosis, Isoquinolines, Crossover study, Cytochrome P-450 CYP2C19, Tolerability, chemistry, 030220 oncology & carcinogenesis, biology.protein, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d3469d701a2bae30c9359dadb5a2a0Test
http://europepmc.org/articles/PMC8453848Test

المؤلفون: Mónica Vázquez-Del Mercado, Hugo Christian Monroy-Ramirez, Jorge Gutiérrez-Cuevas, Jesús García-Bañuelos, José Alfredo Domínguez-Rosales, Jose Navarro-Partida, Jose Vera-Cruz, Arturo Santos-Garcia, Ana Sandoval-Rodriguez, Juan Armendáriz-Borunda, Jorge Silva-Gomez, Alejandra Meza-Rios, Marina Galicia-Moreno, Bart Staels

المصدر: Hepatology Communications, Vol 4, Iss 3, Pp 434-449 (2020)
Hepatology Communications

مصطلحات موضوعية: medicine.medical_specialty, Hepatology, biology, Sirtuin 1, Chemistry, Insulin, medicine.medical_treatment, Insulin tolerance test, Original Articles, Pirfenidone, medicine.disease, Glucagon, Insulin resistance, Endocrinology, Internal medicine, biology.protein, medicine, Original Article, lcsh:Diseases of the digestive system. Gastroenterology, Resistin, lcsh:RC799-869, Protein kinase A, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99af8219088eaf33fb768ca2bebfe3a1Test
https://doi.org/10.1002/hep4.1474Test

المؤلفون: Adrienne R. Wells, Kai P. Leung

المصدر: Biochemical and Biophysical Research Communications. 521:646-651

مصطلحات موضوعية: Adult, 0301 basic medicine, Cicatrix, Hypertrophic, Pyridones, Biophysics, Scars, Biochemistry, Transforming Growth Factor beta1, Extracellular matrix, 03 medical and health sciences, Hypertrophic scar, 0302 clinical medicine, Fibrosis, medicine, Humans, Myofibroblasts, Molecular Biology, Cells, Cultured, Skin, biology, business.industry, Cell Differentiation, Cell Biology, Transforming growth factor beta, Pirfenidone, medicine.disease, Extracellular Matrix, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, medicine.symptom, business, Wound healing, Myofibroblast, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6185a19547373fc1d03131589e22d868Test
https://doi.org/10.1016/j.bbrc.2019.10.177Test

المؤلفون: Ahmed A. Shaaban, Dalia H. El-Kashef, Dina S. El-Agamy

المصدر: Pharmacological Reports. 71:774-781

مصطلحات موضوعية: Male, Arginine, Pyridones, Apoptosis, Pharmacology, medicine.disease_cause, Antioxidants, Lipid peroxidation, Superoxide dismutase, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Animals, Pancreas, biology, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, Glutathione, Pirfenidone, medicine.disease, Disease Models, Animal, Oxidative Stress, Pancreatic Function Tests, Pancreatitis, chemistry, 030220 oncology & carcinogenesis, Acute Disease, biology.protein, Cytokines, 030217 neurology & neurosurgery, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465b261e2c7cb97806a427b2b0af51e0Test
https://doi.org/10.1016/j.pharep.2019.04.005Test

المؤلفون: Patrick Andre, Martin Decaris, Chun Chen, Munoz Manuel, Hom Timothy, Scott M. Turner, Ming Chen, Tushar J. Desai, Megan M. Marlow, Cha Jacob, Eric Lefebvre, Steve S. Ho, Paul J. Wolters, Shaoyi Huang, Eve-Irene Lepist, Katerina Leftheris, David J Morgans, Lisa Hooi, Johanna R. Schaub, Vikram R. Rao, Jianfeng Wu, Marina Fridlib, Fernando Rock, Megi Rexhepaj, Erine H. Budi, Prerna Kotak, Gail Lee, Shamra Martin

المصدر: Respiratory research, vol 22, iss 1
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Precision-cut lung slice, Respiratory System, αv integrin, alpha(v) integrin, Cardiorespiratory Medicine and Haematology, Inbred C57BL, Mice, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Receptors, Pulmonary fibrosis, Phosphorylation, alpha 1 Chain, Lung, biology, Transforming growth factor-β, Pirfenidone, Transforming growth factor-beta, medicine.anatomical_structure, 5.1 Pharmaceuticals, Respiratory, Nintedanib, Antifibrotic Agents, Development of treatments and therapeutic interventions, Cell activation, Type I collagen, Signal Transduction, medicine.drug, Integrin, Clinical Sciences, Collagen Type I, Cell Line, Diseases of the respiratory system, Bleomycin, Rare Diseases, medicine, Animals, Humans, Vitronectin, Smad3 Protein, PLN-74809, RC705-779, Integrin alpha6beta1, Animal, Epithelial Cells, Fibroblasts, medicine.disease, Coculture Techniques, Idiopathic Pulmonary Fibrosis, chemistry, Disease Models, Cancer research, biology.protein, Antifibrotic

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8943da51a8a3553a1e3711bc9a9ed07Test
https://escholarship.org/uc/item/5q12m0vqTest

المؤلفون: Jean Paul Thiery, Ehsan Sarafraz-Yazdi, Thomas R. Cox, Hamidreza Aboulkheyr Es, Majid Ebrahimi Warkiani

المصدر: Cancers, Vol 13, Iss 5118, p 5118 (2021)
Cancers
Volume 13
Issue 20

مصطلحات موضوعية: YAP1, Cancer Research, Stromal cell, CD44, Spheroid, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Biology, medicine.disease, pirfenidone (PFD), Article, cancer-associated fibroblasts (CAFs), Oncology, embryonic structures, Carcinoma, medicine, Cancer research, biology.protein, Cancer-Associated Fibroblasts, 1112 Oncology and Carcinogenesis, Epithelial–mesenchymal transition, tumor microenvironment (TME), 3D microfluidic device, Breast carcinoma, epithelial–mesenchymal transition (EMT), RC254-282

وصف الملف: Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce3f2614fe10f065424cc6e6c6fca06Test
https://hdl.handle.net/10453/167090Test

المؤلفون: Vladimira Lostakova, Radka Bittenglova, Simona Littnerová, Pavlína Lisá, Eva Kriegova, Tomas Snizek, Hana Suldova, Michael Doubek, Martina Plačková, Martina Sterclova, Pavlina Musilova, Martina Vasakova, Lenka Šišková, Vladimir Bartos, Martina Doubková, Jana Psikalova, Petra Schneiderova, Monika Zurkova

المصدر: Ther Adv Respir Dis
Therapeutic Advances in Respiratory Disease, Vol 15 (2021)

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Single-nucleotide polymorphism, 03 medical and health sciences, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Diseases of the respiratory system, 0302 clinical medicine, Internal medicine, medicine, Pharmacology (medical), 030304 developmental biology, Original Research, 0303 health sciences, biology, RC705-779, business.industry, Desmoplakin, Pirfenidone, medicine.disease, 3. Good health, 030228 respiratory system, chemistry, biology.protein, Nintedanib, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085ba847fd6bdfb3daff573e1c43b896Test
https://europepmc.org/articles/PMC8442489Test/