المؤلفون: Wilson, Nicholas S, Huntington, Nicholas D

المصدر: Immunology & Cell Biology; Jan2024, Vol. 102 Issue 1, p8-11, 4p

مصطلحات موضوعية: SMALL molecules, PHOSPHATASE inhibitors, T cell receptors, IMMUNE checkpoint inhibitors, DRUG discovery, BIOLOGY, PROGRAMMED cell death 1 receptors, MITOGEN-activated protein kinase phosphatases

المؤلفون: Marquis, Miriam^1,2, Boulet, Salix¹, Mathien, Simon³, Rousseau, Justine^3,4, Thébault, Paméla¹, Daudelin, Jean-François¹, Rooney, Julie¹, Turgeon, Benjamin^3,4, Beauchamp, Claudine¹, Meloche, Sylvain^3,4, Labrecque, Nathalie^1,2,5 nathalie.labrecque@umontreal.ca

المصدر: PLoS ONE. Jan2014, Vol. 9 Issue 1, p1-11. 11p.

مصطلحات موضوعية: *MITOGEN-activated protein kinase phosphatases, *T cell receptors, *CYTOLOGY, *LABORATORY mice, *ANTIGENS, *PHOSPHORYLATION, *CD3 antigen

المؤلفون: Osaki, Luciana H.¹ luciana.osaki@usp.br, Gama, Patricia¹

المصدر: PLoS ONE. Jun2013, Vol. 8 Issue 6, p1-7. 7p.

مصطلحات موضوعية: *MITOGEN-activated protein kinase phosphatases, *CELLULAR signal transduction, *GENETIC regulation, *PHOSPHORYLATION, *THREONINE, *CELL proliferation, *IMMUNOHISTOCHEMISTRY, *GASTRIC mucosa, *POSTNATAL development in animals, *LABORATORY rats

المؤلفون: Da Bin Kim, Myung-Shin Lee, Hong Seok Kim, Haeun Ko, Seung Ro Han, Jisu Lee, Yun Hee Kang, Seyoun Park

المصدر: Molecules and Cells

مصطلحات موضوعية: Male, mitogen-activated protein kinase phosphatase 3, DUSP6, Transfection, Mice, Cell Line, Tumor, Tumor Microenvironment, Animals, Humans, Protein kinase A, Molecular Biology, Tumor microenvironment, biology, Tumor hypoxia, hypoxia-inducible factor-1α, Kinase, Chemistry, hypoxia, Cell Biology, General Medicine, Cell Hypoxia, Cell biology, colon cancer, Tumor progression, Cancer cell, Colonic Neoplasms, biology.protein, MAPK phosphatase, Mitogen-Activated Protein Kinase Phosphatases, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a245422b5eee6f22763604fb186fffTest
http://europepmc.org/articles/PMC8560588Test

المؤلفون: Chien Fu Chen, Nam Nhut Phan, Chung-Chieh Chiao, I-Jeng Yeh, Jui-Hsiang Hung, Zhengda Sun, Meng-Chi Yen, Chih-Yang Wang, Hui Ping Hsu, Ming Derg Lai, Yen-Hung Wu

المصدر: Journal of Microbiology, Immunology and Infection, Vol 54, Iss 5, Pp 845-857 (2021)
Journal of Microbiology, Immunology, and Infection

مصطلحات موضوعية: Lung adenocarcinoma, 0301 basic medicine, Lung Neoplasms, viruses, Chemokine CXCL2, Cyclic AMP Response Element-Binding Protein A, medicine.disease_cause, TNFAIP3, Disease Outbreaks, Middle East respiratory syndrome coronavirus (MERS-CoV), 0302 clinical medicine, Connectivity map, Immunology and Allergy, 030212 general & internal medicine, Coronavirus, virus diseases, Blood Proteins, General Medicine, TCF4, QR1-502, Infectious Diseases, Middle East Respiratory Syndrome Coronavirus, Dual-Specificity Phosphatases, Original Article, Coronavirus Infections, Microbiology (medical), Bioinformatics, Middle East respiratory syndrome coronavirus, 030106 microbiology, Adenocarcinoma of Lung, Biology, Microbiology, 03 medical and health sciences, Immune system, microRNA, medicine, Humans, Protein Interaction Domains and Motifs, Gene, Tumor Necrosis Factor alpha-Induced Protein 3, miRNA, General Immunology and Microbiology, SARS-CoV-2, COVID-19, RNA, Epithelial Cells, Virology, MicroRNAs, Mitogen-Activated Protein Kinase Phosphatases, Antimicrobial Cationic Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128b9e18643730d51026d8dd3cfa8695Test
https://doi.org/10.1016/j.jmii.2021.03.007Test

المؤلفون: Jessy V. van Asperen, Miriam E. van Strien, Emma J. van Bodegraven, Coen B J van Deursen, Oscar M. J. A. Stassen, Pierre A. Robe, Elly M. Hol, Jacqueline A. Sluijs

المساهمون: Cell-Matrix Interact. Cardiov. Tissue Reg.

المصدر: The FASEB Journal, 33(11), 12941-12959. FASEB

مصطلحات موضوعية: 0301 basic medicine, MAP Kinase Kinase 4, Biochemistry, Mitogen-Activated Protein Kinase Phosphatases/genetics, Extracellular matrix, 0302 clinical medicine, Phosphorylation, Intermediate filament, Cytoskeleton, Tumor, Glial fibrillary acidic protein, biology, Brain Neoplasms, Chemistry, cytoskeleton, Glioma, Gene Knockdown Techniques, Dual-Specificity Phosphatases, Glioma/metabolism, Biotechnology, intermediate filaments, extracellular matrix, Phosphatase, GFAP isoforms, Dual-Specificity Phosphatases/genetics, Cell Line, Focal adhesion, 03 medical and health sciences, glioblastoma multiforme, Cell Line, Tumor, Glial Fibrillary Acidic Protein, Genetics, medicine, Humans, Molecular Biology, Alternative splicing, Extracellular Matrix/metabolism, medicine.disease, Laminin/metabolism, Alternative Splicing, 030104 developmental biology, MAP Kinase Kinase 4/metabolism, Cancer research, biology.protein, Mitogen-Activated Protein Kinase Phosphatases, Laminin, Glial Fibrillary Acidic Protein/genetics, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Brain Neoplasms/metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f98a81dfc825cd528e08052a5e406fTest
https://research.tue.nl/en/publications/4b991fe4-0534-4fa6-95b6-61354ccf9ca8Test

المؤلفون: Xiaowu Xu, Shunrong Ji, Zheng Zhang, Qifeng Zhuo, Wensheng Liu, Zeng Ye, Yi Qin, Wenyan Xu, Xianjun Yu, Mengqi Liu, Guixiong Fan, Qiangsheng Hu

المصدر: Cancer Letters. 499:265-278

مصطلحات موضوعية: STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, MAP Kinase Signaling System, Kaplan-Meier Estimate, Histones, Mice, 03 medical and health sciences, Pancreatectomy, 0302 clinical medicine, Cell Line, Tumor, Biomarkers, Tumor, Animals, Humans, Gene silencing, Gene Silencing, Epigenetics, Promoter Regions, Genetic, STAT3, Pancreas, Cell Proliferation, biology, Cell growth, Chemistry, Gene Expression Profiling, Promoter, Histone-Lysine N-Methyltransferase, DNA Methylation, Prognosis, Xenograft Model Antitumor Assays, Up-Regulation, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, 030104 developmental biology, Oncology, Cell culture, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Phosphorylation, Chromatin immunoprecipitation, Carcinoma, Pancreatic Ductal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510b8428592492f981d36b8533bc5fdcTest
https://doi.org/10.1016/j.canlet.2020.11.023Test

المؤلفون: Snehal Pandav Mudrale, Kakoli Bose, Saujanya Acharya, Shubhankar Dutta

المصدر: Biochemical and Biophysical Research Communications. 533:607-612

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Proteome, medicine.medical_treatment, PDZ domain, Biophysics, Computational biology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Dual-specificity phosphatase, Human proteome project, medicine, Humans, Computer Simulation, Peptide library, Molecular Biology, Binding selectivity, Serine protease, Binding Sites, Protease, biology, Chemistry, Cell Biology, High-Temperature Requirement A Serine Peptidase 2, Ligand (biochemistry), 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec46789d5d32728c9f8e7fb7e6d2205Test
https://doi.org/10.1016/j.bbrc.2020.09.062Test

المؤلفون: Fabrice Valette, Pere Santamaria, Jean-François Bach, Claudio Scazzocchio, Sophie Candon, Sebastien Lemoine, Sara Hildebrand, Peipei Hu, Bruce Beutler, Sylvaine You, Francina Langa-Vives, Stephen Aplin Lyon, Anne-Perrine Foray, Eva Marie Y. Moresco, Chun Hui Bu, Lucienne Chatenoud, Coralie Pecquet, Darui Xu, Cindy Marquet, Michael Dumas, Lindsay Scott, Tao Wang

المساهمون: Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), University of Texas Southwestern Medical Center [Dallas], Centre d'Ingénierie génétique murine - Mouse Genetics Engineering Center (CIGM), Institut Pasteur [Paris] (IP), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS), University of Calgary, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Imperial College London, Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Funding was provided by NIH Grant R01 AI125581 (B.B.), NIH Grant U19 AI100627 (B.B.), European Research Council Advanced Grant, Hygiene No. 250290 (J.-F.B.), Institut National de la Santé et de la Recherche Scientifique (L.C.), Fondation Day Solvay (L.C.), and the Lyda Hill Foundation (B.B.)., European Project: 250290,EC:FP7:ERC,ERC-2009-AdG,HYGIENE(2010), LANGA VIVES, FRANCINA, THE HYGIENE HYPOTHESIS : REVISITING THE CONCEPT BY INTEGRATING EPIDEMIOLOGY AND MECHANISTIC STUDIES - HYGIENE - - EC:FP7:ERC2010-08-01 - 2015-07-31 - 250290 - VALID

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (47), pp.e2112032118. ⟨10.1073/pnas.2112032118⟩
Proc Natl Acad Sci U S A

مصطلحات موضوعية: Male, type 1 diabetes, Nod, Major histocompatibility complex, medicine.disease_cause, Autoimmune Diseases, Major Histocompatibility Complex, Islets of Langerhans, Mice, Germline mutation, Mice, Inbred NOD, medicine, Animals, Humans, Missense mutation, Genetic Predisposition to Disease, Germ-Line Mutation, NOD mice, Autoimmune disease, Genetics, Mutation, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Multidisciplinary, biology, autoimmunity, Haplotype, Biological Sciences, medicine.disease, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, Haplotypes, biology.protein, Dual-Specificity Phosphatases, Mitogen-Activated Protein Kinase Phosphatases, Female, genetic mapping, NOD mouse, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ba665602db471fa72ce8128e19ff67Test
https://doi.org/10.1073/pnas.2112032118Test

المؤلفون: Shantá D. Hinton, Emma Marie Wilber Hepworth

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 12595, p 12595 (2021)
International Journal of Molecular Sciences

مصطلحات موضوعية: MAPK/ERK pathway, MAPK phosphatase (MKP), MAP Kinase Signaling System, MAPK phosphoserine/threonine/tyrosine-binding protein (MK-STYX), kinase, QH301-705.5, pseudophosphatase, Phosphatase, Review, Biology, Catalysis, Inorganic Chemistry, chemistry.chemical_compound, Humans, mitogen-activated protein kinase (MAPK), Physical and Theoretical Chemistry, Phosphorylation, Biology (General), Protein kinase A, phosphoserine/threonine/tyrosine-interacting protein (STYX), Molecular Biology, QD1-999, Spectroscopy, Kinase, Organic Chemistry, Intracellular Signaling Peptides and Proteins, General Medicine, Cell cycle, protein tyrosine phosphatases (PTPs), Computer Science Applications, Cell biology, TAK1-binding protein (TAB 1), Chemistry, extracellular signal-regulated kinase (ERK), chemistry, Phosphoserine, Mitogen-Activated Protein Kinase Phosphatases, dual-specificity phosphatases (DUSPs), Signal transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33ffbe6b2bd656e3382b11e3193b78aTest
https://www.mdpi.com/1422-0067/22/22/12595Test