نتائج البحث

1

Expression of programmed death ligand 1 in drug-resistant osteosarcoma: An exploratory study

المؤلفون: Fei Chu, Nicholas J. Skertich, Jeffrey A. Borgia, Imad Tarhoni, Stephen Szajek, Mary Beth Madonna

المصدر: Surgery Open Science, Vol 6, Iss, Pp 10-14 (2021)
Surgery Open Science

مصطلحات موضوعية: WT, wild type, Herpesvirus entry mediator, CD80, cluster of differentiation 80, TLR-2, Toll like receptor 2, RD1-811, PD-L1, programmed death ligand 1, GITRL, ligand for receptor TNFRSF18/AITR/GITR, CTLA-4, cytotoxic T-lymphocyte-associated protein 4, ICOS, inducible T-cell costimulatory (ICOS), BTLA, B- and T-lymphocyte attenuator, Biology, Article, DoxR, doxorubicin resistant, Western blot, medicine, PD-L2, programmed death ligand 2, HVEM, herpesvirus entry mediator, TIM-3, T-cell immunoglobulin-3, Matrigel, LAG-3, lymphocyte-activation gene-3, CD40, cluster of differentiation 40, Cluster of differentiation, medicine.diagnostic_test, CD86, cluster of differentiation 86, CD27, cluster of differentiation 27, GITR, glucocorticoid-induced TNFR-related protein, Ligand (biochemistry), medicine.disease, PD-1, programmed death 1, FDA, Food and Drug Administration, In vitro, Cell culture, CD28, cluster of differentiation 28, Cancer research, Osteosarcoma, Surgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4b311880ebd1fc0b8ba946d799acefTest
http://www.sciencedirect.com/science/article/pii/S2589845021000129Test

2

Fibrinogen-like protein 1 (FGL1): the next immune checkpoint target

المؤلفون: Mingfang Zhao, Ruoyu Wang, Heming Li, Wenjing Qian

المصدر: Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)
Journal of Hematology & Oncology

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Programmed cell death, LAG3, Epithelial-Mesenchymal Transition, medicine.drug_class, Review, Biology, Monoclonal antibody, Antigens, CD, LAG-3, Internal medicine, Neoplasms, medicine, Animals, Humans, Diseases of the blood and blood-forming organs, Epithelial–mesenchymal transition, Molecular Targeted Therapy, Molecular Biology, Immune Checkpoint Inhibitors, FGL1, RC254-282, Hematology, Fibrinogen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Biomarker, Ligand (biochemistry), Lymphocyte Activation Gene 3 Protein, Immune checkpoint, Oncology, Cancer research, Biomarker (medicine), Immune resistance, Tumor Escape, Immunotherapy, RC633-647.5, Immune checkpoint blockade

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c863141164b6748972c800d80e9c95f0Test
https://doaj.org/article/bde087ed0c634ef7af10c3e368eb935bTest

3

دورية أكاديمية

Common features of regulatory T cell specialization during Th1 responses

المؤلفون: Littringer, Katharina, Moresi, Claudia, Rakebrandt, Nikolas, Zhou, Xiaobei, Schorer, Michelle, Dolowschiak, Tamas, Kirchner, Florian, Rost, Felix, Keller, Christian W, McHugh, Donal, LeibundGut-Landmann, Salomé, Robinson, Mark D, Joller, Nicole

المصدر: Littringer, Katharina; Moresi, Claudia; Rakebrandt, Nikolas; Zhou, Xiaobei; Schorer, Michelle; Dolowschiak, Tamas; Kirchner, Florian; Rost, Felix; Keller, Christian W; McHugh, Donal; LeibundGut-Landmann, Salomé; Robinson, Mark D; Joller, Nicole (2018). Common features of regulatory T cell specialization during Th1 responses. Frontiers in Immunology, 9:1344.

مصطلحات موضوعية: Institute of Molecular Life Sciences, Institute of Virology, Institute of Experimental Immunology, 570 Life sciences, biology, CD85k, CXCR3, Lag-3, T-bet, Th1, Treg cells, co-inhibitory receptors

وصف الملف: application/pdf

العلاقة: https://www.zora.uzh.ch/id/eprint/152029/1/PU584.pdfTest; info:pmid/29951069; urn:issn:1664-3224

الإتاحة: https://doi.org/10.5167/uzh-15202910.3389/fimmu.2018.01344Test
https://www.zora.uzh.ch/id/eprint/152029Test/
https://www.zora.uzh.ch/id/eprint/152029/1/PU584.pdfTest

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النص الكامل

4

LAG-3 expression in the inflammatory microenvironment of glioma

المؤلفون: Katharina Feldmann, Adelheid Wöhrer, Maximilian J. Mair, Barbara Kiesel, Matthias Preusser, Anna S. Berghoff, Leonhard Müllauer, Karin Dieckmann, Georg Widhalm

المصدر: Journal of Neuro-Oncology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6d8bf816fa704128a06a915cfa36c1Test
https://doi.org/10.1007/s11060-021-03721-xTest

5

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer–T cell coculture models

المؤلفون: Zul Fazreen, Kosaku Mimura, Nicholas Syn, Yuko Nakayama, Jin-Fen Xiao, Wei Peng Yong, Richie Soong, Koji Kono, Bernadette Reyna Asuncion, Ley-Fang Kua

المصدر: Gastric Cancer

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, medicine.medical_treatment, T cell, Programmed Cell Death 1 Receptor, Tim-3, 03 medical and health sciences, 0302 clinical medicine, Immune system, Antigens, CD, Stomach Neoplasms, Cell Line, Tumor, PD-L1, PD-1, Humans, Medicine, Cytotoxic T cell, Lectins, C-Type, Cytotoxicity, Aged, Singapore, MHC class II, biology, business.industry, Lag-3, Gastroenterology, General Medicine, Immunotherapy, Survival Analysis, Gene Expression Regulation, Neoplastic, CTL, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Original Article, Combinatorial immunotherapy, Female, Gastric cancer, business, Cell Adhesion Molecules

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b04fb8da0f849665868f13e779a7156Test
https://doi.org/10.1007/s10120-020-01151-8Test

6

Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor

المؤلفون: Georgina H. Mason, David K. Cole, Frédéric Triebel, Awen Gallimore, Andrew James Godkin, Bruce J. MacLachlan, Alexander Greenshields-Watson

المصدر: European Journal of Immunology

مصطلحات موضوعية: 0301 basic medicine, Molecular immunology and signaling, LAG3, T-Lymphocytes, medicine.medical_treatment, T cell, Immunology, Cell, T cells, Receptors, Antigen, T-Cell, Biology, immune checkpoint inhibitors, Jurkat Cells, 03 medical and health sciences, 0302 clinical medicine, LAG‐3, Costimulatory and Inhibitory T-Cell Receptors, Downregulation and upregulation, Cancer immunotherapy, Antigens, CD, HLA Antigens, Cell Line, Tumor, Neoplasms, medicine, Humans, Immunology and Allergy, Basic, Receptor, Research Articles, cancer immunotherapy, Lymphocyte Activation Gene 3 Protein, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, CD4 Antigens, pHLA‐II, biology.protein, Research Article|Basic, Antibody, Function (biology), 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295dfce87346771adca4707fe21a976bTest
https://doi.org/10.1002/eji.202048753Test

7

Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer

المؤلفون: Janik Puttemans, Marleen Keyaerts, Pieterjan Debie, Nick Devoogdt, L. De Beck, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Quentin Lecocq, Karine Breckpot, Robin Maximilian Awad, Y. De Vlaeminck

المساهمون: Laboratory of Molecullar and Cellular Therapy, Faculty of Medicine and Pharmacy, Medical Imaging, Clinical sciences, Supporting clinical sciences, Basic (bio-) Medical Sciences, Department of Bio-engineering Sciences, Cellular and Molecular Immunology, Nuclear Medicine

المصدر: EJNMMI Research, Vol 11, Iss 1, Pp 1-13 (2021)
EJNMMI Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867ec67d785e9c2e394420ce275bd7d7Test
https://doi.org/10.1186/s13550-021-00857-9Test

8

Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade

المؤلفون: Quentin Lecocq, Karine Breckpot, Geert Raes, Marleen Keyaerts, Cleo Goyvaerts, Kris Thielemans, Yannick De Vlaeminck, Robin Maximilian Awad, Thomas Ertveldt, Wout De Mey, Nick Devoogdt

المساهمون: Laboratory of Molecullar and Cellular Therapy, Faculty of Medicine and Pharmacy, Basic (bio-) Medical Sciences, Department of Bio-engineering Sciences, Cellular and Molecular Immunology, Vriendenkring VUB, Supporting clinical sciences, Medical Imaging, Nuclear Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e4f60f96e8137e7509229a2545348aTest
https://hdl.handle.net/20.500.14017/949d9ece-83fb-4432-a911-77eb0678aa27Test

9

Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses

المؤلفون: Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang

المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: TIM-3, T cell immunoglobulin and mucin domain 3, H3K27me3, tri-methylation of lysine 27 on histone H3, MDSCs, myeloid-derived suppressor cells, medicine.medical_treatment, Review, TAA, tumor-associated antigen, DC, dendritic cell, 0302 clinical medicine, EZH2, enhancer of zeste homolog 2, LAG-3, lymphocyte activation gene-3, CTLA-4, cytotoxic T lymphocyte antigen 4, Medicine, BETi, bromodomain and extra-terminal motif inhibitors, General Pharmacology, Toxicology and Pharmaceutics, FOXP3, forkhead box P3, HDACi, histone deacetylase inhibitor, Cancer, 0303 health sciences, ACE1, angiotensin converting enzyme, CLL, chronic lymphocytic leukemia, biology, IDO, indoleamine 2,3-dioxygenase, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tregs, regulatory T cells, PD-L1/PD-1 blockade, CCL22 (MDC), macrophage-derived chemokine, Immunotherapy, TET2, ten-eleven translocation 2, CTLs, cytotoxic T lymphocytes, FDA, U. S. Food and Drug Administration, PD-L1, programmed cell death ligand 1, T cell, CTA, cancer testis antigen, Immune cycle, TIL, tumor infiltrating lymphocytes, Epigenetic regulation, OS, overall survival, 03 medical and health sciences, Immune system, Antigen, PD-L1, TH-1, T helper type 1, DNMT1, DNA methyltransferase 1, MHC, major histocompatibility complex, CX3CL1, C-X3-C motif chemokine ligand 1, IFN-γ, interferon-gamma, 030304 developmental biology, business.industry, lcsh:RM1-950, biochemical phenomena, metabolism, and nutrition, medicine.disease, CXCL, CXC chemokine ligand, Blockade, lcsh:Therapeutics. Pharmacology, APC, antigen-presenting cell, UHRF1, ubiquitin-like PHD and RING finger domain-containing 1, 5-AzaC, 5-azacitidine, ACP1, human red cell acid phosphatase, biology.protein, Cancer research, bacteria, DNMTi, DNA methyltransferase inhibitors, PD-1, programmed cell death 1, business, PRC2, polycomb repressive complex 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ca7b0479f6fea7a89a3e1eb06905c5Test
https://doi.org/10.1016/j.apsb.2019.09.006Test

10

A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8+ T cell responses

المؤلفون: Yuanming Qi, Guodong Li, Hongfei Wang, Xinghua Sui, Yanfeng Gao, Guanyu Chen, Wanqiong Li, Wenjie Zhai, Xiuman Zhou

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 1047-1060 (2020)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5371ad86abe5d20d04e1887e733eb2Test
http://europepmc.org/articles/PMC7332792Test

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