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المؤلفون: David G. Schatz, Jean-Marie Buerstedde, Suhas S.P. Rao, Jukka Alinikula, Filip Šenigl, Yaakov Maman, Ravi K. Dinesh, Lubomira Pecnova, David Weisz, Jiri Hejnar, Rafael Casellas, Rashu B. Seth, Arina D. Omer, Erez Lieberman Aiden
المصدر: Cell reports
Cell Reports, Vol 29, Iss 12, Pp 3902-3915.e8 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Somatic hypermutation, RNA polymerase II, Computational biology, Genome, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Cell Line, Tumor, Cytidine Deaminase, Activation-induced (cytidine) deaminase, Humans, Enhancer, lcsh:QH301-705.5, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, biology, Lentivirus, Chromatin, 030104 developmental biology, Enhancer Elements, Genetic, HEK293 Cells, lcsh:Biology (General), Mutation, biology.protein, RNA Polymerase II, Somatic Hypermutation, Immunoglobulin, 030217 neurology & neurosurgery, Plasmids
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a368ddd3906f056ea5c400d34747c64Test
https://doi.org/10.2139/ssrn.3383796Test -
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المؤلفون: Shikha Sharma, Julian E. Sale, Teonchit Nuamchit, Hiroshi Arakawa, Jean-Marie Buerstedde, Kathryn H. Steele, Nicholas P.J. Brindle
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Directed Evolution, Somatic hypermutation, Ligand Binding Protein, Plasma protein binding, Protein Engineering, Biochemistry, Receptor tyrosine kinase, Angiopoietin-2, 03 medical and health sciences, 0302 clinical medicine, Cell surface receptor, Humans, Molecular Biology, 030304 developmental biology, 0303 health sciences, Endothelial Cell, biology, HEK 293 cells, Cell Surface Receptor, Cell Biology, Angiopoietin receptor, Molecular biology, Receptor, TIE-2, Ligand-binding Protein, Cell biology, Protein Structure, Tertiary, HEK293 Cells, Ectodomain, 030220 oncology & carcinogenesis, Protein Structure and Folding, biology.protein, Angiogenesis, Directed Molecular Evolution, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1831936e20d8708d4a4802c0db100abTest
http://europepmc.org/articles/PMC3829167Test -
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المصدر: The Journal of Immunology. 191:1556-1566
مصطلحات موضوعية: Genetics, Reporter gene, Immunology, Immunology and Allergy, Somatic hypermutation, Locus (genetics), E-box, Cytidine deaminase, Biology, Sequence motif, Genome, Gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::59827adac5b35501fc0896414094d2a3Test
https://doi.org/10.4049/jimmunol.1300969Test -
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المؤلفون: Jean-Marie Buerstedde, Hiroshi Arakawa
المصدر: Philosophical Transactions of the Royal Society B: Biological Sciences. 364:639-644
مصطلحات موضوعية: Genetics, biology, Genetic Variation, Somatic hypermutation, Locus (genetics), Review, Cytidine deaminase, General Biochemistry, Genetics and Molecular Biology, Cell Line, Regulatory sequence, Cytidine Deaminase, Proliferating Cell Nuclear Antigen, Uracil-DNA glycosylase, Activation-induced (cytidine) deaminase, biology.protein, Animals, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, Gene conversion, Uracil-DNA Glycosidase, General Agricultural and Biological Sciences, Chickens, Gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9839fedd2b59c343625d816164555fTest
https://doi.org/10.1098/rstb.2008.0202Test -
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المؤلفون: Jean-Marie Buerstedde, Keizo Tano, Masami Watanabe, Elena K. Braithwaite, Eiichiro Sonoda, Hiroshi Arakawa, Kenjiro Asagoshi, Shunichi Takeda, Jun Nakamura, Samuel H. Wilson, Rajendra Prasad
المصدر: DNA Repair. 6:869-875
مصطلحات موضوعية: DNA Repair, Cell Survival, DNA polymerase, DNA repair, DNA damage, viruses, DNA polymerase beta, Biochemistry, Article, Cell Line, chemistry.chemical_compound, Animals, Molecular Biology, DNA Polymerase beta, Polymerase, chemistry.chemical_classification, Dose-Response Relationship, Drug, Models, Genetic, biology, Hydrogen Peroxide, Cell Biology, Base excision repair, Molecular biology, Oxygen, Enzyme, chemistry, biology.protein, Chickens, NADP, DNA, DNA Damage, Plasmids
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b235ab9a837af645e4382ce25ff7f14bTest
https://doi.org/10.1016/j.dnarep.2007.01.011Test -
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المؤلفون: Thomas Helleday, Hiroshi Arakawa, Yoshihito Taniguchi, Weihua Zeng, Jean-Marie Buerstedde, Hirobumi Teraoka, Julian E. Sale, Akira Yasui, Yasuhiro Murakawa, Shunichi Takeda, Kyoko Yokomori, Alihossein Saberi, Dávid Szüts, Li Lan, Helfrid Hochegger
المصدر: Mol. Cell. Biol. 27, 2562-2571 (2007)
مصطلحات موضوعية: DNA Repair, Ubiquitin-Protein Ligases, Poly ADP ribose polymerase, Saccharomyces cerevisiae, Topoisomerase-I Inhibitor, Cell Line, PARP1, Postreplication repair, Animals, Humans, DNA Breaks, Double-Stranded, Ku Autoantigen, Molecular Biology, Polymerase, Recombination, Genetic, biology, fungi, Antigens, Nuclear, Articles, Cell Biology, biology.organism_classification, Molecular biology, DNA-Binding Proteins, Non-homologous end joining, enzymes and coenzymes (carbohydrates), biology.protein, Camptothecin, Poly(ADP-ribose) Polymerases, Topoisomerase I Inhibitors, Homologous recombination, Chickens
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775e4473882301a6ccf0b683651a872aTest
https://doi.org/10.1128/mcb.01243-06Test -
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المؤلفون: J. Bachl, Jean-Marie Buerstedde, Randolph B. Caldwell
المصدر: Cytogenet. Genome Res. 117, 189-194 (2007)
مصطلحات موضوعية: B-Lymphocytes, Focus (computing), business.industry, Gene Expression, Biology, Cell Line, Protein evolution, Biotechnology, Green fluorescent protein, Directed enzyme evolution, In-vitro recombination, Somatic hypermutation, Gene conversion, Phage display, Region hypermutation, Antibody diversity, Escherichia-coli, Lympocyte line, B cell line, Genes, Reporter, Mutation, Genetics, Animals, Humans, business, Chickens, Molecular Biology, Genetics (clinical), Pharmaceutical industry
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8c0db9cc2e133ab83b2b3ef573c606Test
https://doi.org/10.1159/000103179Test -
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المساهمون: Schoetz, U, Cervelli, Manuela, Wang, Yd, Fiedler, P, Buerstedde, Jm
المصدر: The Journal of Immunology. 177:395-400
مصطلحات موضوعية: Genetic Markers, DNA, Complementary, activation-induced cytidine deaminase, Molecular Sequence Data, Immunology, Ig hypermutation, Receptors, Antigen, B-Cell, Somatic hypermutation, DT 40 cell, Cell Line, Avian Proteins, chemistry.chemical_compound, E2A gene, Transcription (biology), Cytidine Deaminase, Activation-induced (cytidine) deaminase, Animals, Immunology and Allergy, Gene silencing, Gene Silencing, Enhancer, Gene, E12 protein, Base Sequence, biology, Genetic Complementation Test, Cytidine, Sequence Analysis, DNA, Cytidine deaminase, Molecular biology, Clone Cells, E47 protein, chemistry, biology.protein, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, TCF Transcription Factors, Chickens
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372c52f92fdfa6ef710faac4ad3162bbTest
https://doi.org/10.4049/jimmunol.177.1.395Test -
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المؤلفون: Jean-Marie Buerstedde, Elli Narvi, K. Koskela, Kalle-Pekka Nera, Laura Mustonen, Anne Peippo, Olli Lassila, Perttu Terho, Pekka Kohonen
المصدر: Immunity. 24(3):283-293
مصطلحات موضوعية: Cellular differentiation, Immunology, Biology, Cell biology, medicine.anatomical_structure, Infectious Diseases, Downregulation and upregulation, Cell culture, immune system diseases, hemic and lymphatic diseases, Plasma cell differentiation, medicine, Immunology and Allergy, Secretion, Progenitor cell, Receptor, B cell
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88a949b4062fc35a724cb66df88b895Test
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المؤلفون: Jean-Marie Buerstedde, Huseyin Saribasak, Fatih M. Ipek, Hiroshi Arakawa, Nesibe Nur Saribasak, Joachim W. Ellwart
المصدر: The Journal of Immunology. 176:365-371
مصطلحات موضوعية: Molecular Sequence Data, Immunology, Mutant, Gene Conversion, Deamination, Cell Line, chemistry.chemical_compound, Activation-induced (cytidine) deaminase, Animals, Immunology and Allergy, Gene conversion, Uracil-DNA Glycosidase, B-Lymphocytes, Base Sequence, Genes, Immunoglobulin, biology, Uracil, Cytidine, Molecular biology, chemistry, Uracil-DNA glycosylase, biology.protein, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, Chickens, Cytosine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3f59fc89a396d93e34c4364a9a2ae6Test
https://doi.org/10.4049/jimmunol.176.1.365Test