المؤلفون: Giorgio Perilongo, Luca Bosa, Mara Cananzi, Alberta Leon, Huie Jing, Joselito Sobreira Filho, Antonio Marzollo, Maria Oliva-Hemker, Howard A. Kader, Claudia Mescoli, Yu Zhang, Jing You, James R. Lupski, Anthony L. Guerrerio, Elizabeth Wohler, Maurizio Dalle Carbonare, Davide Colavito, P. Gaio, David Valle, Nara Sobreira, Sangeeta Bade, Richard Kellermayer, Alessandra Biffi, Helen C. Su, Shalini N. Jhangiani, Wesley Tung, Silvia Bresolin, Jennifer E. Posey, Maria Gabelli, Renan Paulo Martin

المصدر: Hum Genet

مصطلحات موضوعية: Male, Proband, Interferon-Induced Helicase, IFIH1, Biology, Inflammatory bowel disease, Article, Child, Preschool, Female, Humans, Infant, Inflammatory Bowel Diseases, Italy, Whole Genome Sequencing, Loss of Function Mutation, 03 medical and health sciences, Genetics, medicine, Human virome, Enteropathy, Expressivity (genetics), Child, Preschool, Interferon-Induced Helicase, Genetics (clinical), Exome sequencing, Immunodeficiency, IFIH1, 030304 developmental biology, 0303 health sciences, 030305 genetics & heredity, medicine.disease, Penetrance, Immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a73a9512fff4d821c03d83812282935Test
https://doi.org/10.1007/s00439-021-02300-4Test

المؤلفون: Qin Yu, Yorgo Modis, Alba Herrero del Valle, Rahul Singh

المساهمون: Yu, Qin [0000-0001-9265-632X], Herrero Del Valle, Alba [0000-0001-8153-6146], Singh, Rahul [0000-0001-8397-0202], Modis, Yorgo [0000-0002-6084-0429], Apollo - University of Cambridge Repository, Herrero del Valle, Alba [0000-0001-8153-6146]

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, 12 (1)
Nature Communications

مصطلحات موضوعية: Models, Molecular, 82/29, Interferon-Induced Helicase, IFIH1, Protein Conformation, ATPase, viruses, General Physics and Astronomy, medicine.disease_cause, 631/45/173, 631/45/535/1258/1259, Adenosine Triphosphate, 0302 clinical medicine, ATP hydrolysis, Interferon, Adenosine Triphosphatases, 0303 health sciences, Mutation, Multidisciplinary, biology, Chemistry, 631/45/500, article, food and beverages, MDA5, Chronic inflammation, 3. Good health, Cell biology, RNA silencing, Enzyme mechanisms, RNA, Viral, Protein Binding, medicine.drug, Science, Allosteric regulation, Mutation, Missense, General Biochemistry, Genetics and Molecular Biology, 96/95, 03 medical and health sciences, medicine, Humans, 82/83, RNA, Double-Stranded, 030304 developmental biology, Inflammation, 631/250/262/2106/2518, Cryoelectron Microscopy, 101/28, fungi, RNA, General Chemistry, Immunity, Innate, HEK293 Cells, 631/250/256/2515, RIG-I-like receptors, biology.protein, Nucleic Acid Conformation, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/zip; text/xml; application/application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be0473d4f75a5612346c5478f88ed7fTest
https://doaj.org/article/4ed51115fdf7407f8d5ba6033a51c511Test

المؤلفون: Zhang Ling, Li Shanshan, Zhang Yamei, Lu Xin, Wang Guo-chun

المصدر: Clinical Rheumatology. 41:757-763

مصطلحات موضوعية: medicine.medical_specialty, Interferon-Induced Helicase, IFIH1, Antisynthetase syndrome, Gastroenterology, Dermatomyositis, Progranulins, Rheumatology, Internal medicine, Humans, Medicine, In patient, Autoantibodies, Retrospective Studies, biology, business.industry, Interstitial lung disease, General Medicine, Prognosis, medicine.disease, MELANOMA DIFFERENTIATION-ASSOCIATED GENE 5, Ferritin, Case-Control Studies, Disease Progression, biology.protein, Antibody, Lung Diseases, Interstitial, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ddddd0424895e13765b59039230266Test
https://doi.org/10.1007/s10067-021-05816-2Test

المؤلفون: Lulu Han, Pei-Hui Wang, Jian Deng, Jing Zhang, Meng Wei Zhuang, Mei Ling Nan, Xue Jing Zhang, Yi Zheng, Chengjiang Gao

المصدر: Journal of Medical Virology

مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, viruses, Virus Replication, SARS‐CoV‐2, 0302 clinical medicine, Interferon, Chlorocebus aethiops, 030212 general & internal medicine, Receptors, Immunologic, skin and connective tissue diseases, Research Articles, RIG-I, virus diseases, Signal transducing adaptor protein, Nucleotidyltransferases, I-kappa B Kinase, antiviral immunity, Infectious Diseases, Vesicular stomatitis virus, DEAD Box Protein 58, 030211 gastroenterology & hepatology, Signal transduction, Plasmids, Signal Transduction, Research Article, IFNs, medicine.drug, Protein Serine-Threonine Kinases, Biology, Transfection, ORF9b, 03 medical and health sciences, COVID‐19, Virology, medicine, Animals, Coronavirus Nucleocapsid Proteins, Humans, Vero Cells, Adaptor Proteins, Signal Transducing, Immune Evasion, SARS-CoV-2, fungi, Membrane Proteins, biochemical phenomena, metabolism, and nutrition, Phosphoproteins, biology.organism_classification, Immunity, Innate, Toll-Like Receptor 3, Adaptor Proteins, Vesicular Transport, HEK293 Cells, Gene Expression Regulation, TRIF, TLR3, Interferon Regulatory Factor-3, Interferons, IRF3, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378faf81bbd134d651ba57cea4c75d0cTest
https://doi.org/10.1002/jmv.27050Test

المؤلفون: Tianqi Yu, Chengxiu Fang, Min Liao, Jiyong Zhou, Jingjing Liu, Nishant Kumar Ojha

المصدر: Archives of Virology

مصطلحات موضوعية: Proteasome Endopeptidase Complex, animal structures, Interferon-Induced Helicase, IFIH1, Viral protein, Infectious bronchitis virus, RNA-dependent RNA polymerase, Coronavirus Papain-Like Proteases, Biology, Protein Serine-Threonine Kinases, medicine.disease_cause, Virus Replication, Cell Line, 03 medical and health sciences, Virology, Chlorocebus aethiops, medicine, Animals, Vero Cells, 030304 developmental biology, Coronavirus, 0303 health sciences, Innate immune system, Deubiquitinating Enzymes, 030306 microbiology, Ubiquitin, MDA5, General Medicine, Interferon-beta, Immunity, Innate, Proteasome, Viral replication, embryonic structures, Original Article, IRF3, Chickens, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b1646f9b78cf524cd344d11e264432Test
http://europepmc.org/articles/PMC8150628Test

المؤلفون: Maiti, Amit K.

المصدر: Immunogenetics

مصطلحات موضوعية: 0301 basic medicine, China, Interferon-Induced Helicase, IFIH1, Genotype, Short Communication, Immunology, Population, Pneumonia, Viral, Biology, medicine.disease_cause, Polymorphism, Single Nucleotide, Herd immunity, 03 medical and health sciences, Betacoronavirus, 0302 clinical medicine, Asian People, Gene Frequency, Polymorphism (computer science), Genetics, medicine, SARS-COV2, Humans, Genetic Predisposition to Disease, Allele, Polymorphism, education, Allele frequency, Pandemics, Coronavirus, IFIH1, education.field_of_study, SARS-CoV-2, COVID-19, Interferon-beta, United States, Minor allele frequency, Black or African American, 030104 developmental biology, Italy, Coronavirus Infections, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcdb0bf91a3ffa1b705122348a76752Test
http://europepmc.org/articles/PMC7394703Test

المؤلفون: Licheng Diao, Hua Cao, Ruofei Shi, K. Xue, Feng Xue, Jian Li, Yeping Ruan, Mengya Chen, Meng Pan, Jie Zheng, Qian Zhao

المصدر: Rheumatology. 61:430-439

مصطلحات موضوعية: Adult, Male, China, Interferon-Induced Helicase, IFIH1, Dermatomyositis, Young Adult, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, medicine, Humans, Distribution (pharmacology), Pharmacology (medical), Aged, Retrospective Studies, 030203 arthritis & rheumatology, biology, business.industry, Mortality rate, Incidence (epidemiology), Interstitial lung disease, MDA5, Middle Aged, Prognosis, medicine.disease, Immunoglobulin Isotypes, Acute Interstitial Pneumonia, Immunology, biology.protein, Female, Antibody, Lung Diseases, Interstitial, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584fd6530165c2d9eb0bbc4c1d20832eTest
https://doi.org/10.1093/rheumatology/keab268Test

المؤلفون: Sun Hur, Hai-Tao Wang

المصدر: Seminars in Cell & Developmental Biology

مصطلحات موضوعية: 0301 basic medicine, RIG-I like receptors, Interferon-Induced Helicase, IFIH1, animal structures, Ubiquitin-Protein Ligases, viruses, Substrate recognition, B30.2-SPRY Domain, Biology, Article, Trim, Substrate Specificity, Tripartite Motif Proteins, 03 medical and health sciences, 0302 clinical medicine, Tripartite Motif, Humans, Tripartite motif protein, Receptors, Immunologic, Adaptor Proteins, Signal Transducing, Innate immunity, Innate immune system, Intracellular Signaling Peptides and Proteins, RNA, Cell Biology, Immunity, Innate, Cell biology, 030104 developmental biology, Gene Expression Regulation, Oligomer, Multigene Family, DEAD Box Protein 58, Interferon Regulatory Factor-3, Signal transduction, PRY-SPRY domain, 030217 neurology & neurosurgery, Signal Transduction, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97af42ec3a99e7d583754f33af941bafTest
https://doi.org/10.1016/j.semcdb.2020.09.013Test

المؤلفون: Ellen De Meester, Alexander Botzki, Leen J M Seys, Peter Vandenabeele, Filip Van Nieuwerburgh, Tuur Muyldermans, Jonathan Maelfait, Bart N. Lambrecht, Evelien Dierick, Bartosz Wiernicki, Katrien Staes, Richard de Reuver

المساهمون: Pulmonary Medicine

المصدر: Cell Reports, Vol 36, Iss 6, Pp 109500-(2021)
Cell Reports, 36(6):109500. Cell Press
CELL REPORTS

مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, Adenosine Deaminase, Aicardi-Goutières syndrome, Adenosine deaminase, DOMAIN, Interferon, ADAPTER PROTEIN, Medicine and Health Sciences, Biology (General), Short Interspersed Nucleotide Elements, IFIH1, RETROELEMENTS, biology, I INTERFERON, Chemistry, Signal transducing adaptor protein, RNA-Binding Proteins, MDA5, MAVS, Cell biology, DEFICIENCY, RNA silencing, Interferon Type I, ADENOSINE-DEAMINASE, medicine.drug, Protein Binding, Heterozygote, Base pair, QH301-705.5, General Biochemistry, Genetics and Molecular Biology, Cell Line, Z-DNA, medicine, Animals, Humans, A-to-I editing, Adaptor Proteins, Signal Transducing, RNA, Double-Stranded, Inflammation, AGS, IDENTIFICATION, MUTATIONS, Z-ALPHA, Immunity, RNA, Biology and Life Sciences, Hematopoiesis, Mice, Inbred C57BL, HEK293 Cells, Animals, Newborn, Mutation, biology.protein, RNA Editing, RESPONSES

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67227824facd3f1ec08aff363d515a37Test
https://doi.org/10.1016/j.celrep.2021.109500Test

المؤلفون: Smriti Mallapaty

المصدر: Nature. 597:166-168

مصطلحات موضوعية: 2019-20 coronavirus outbreak, Interferon-Induced Helicase, IFIH1, Time Factors, T Follicular Helper Cells, Coronavirus disease 2019 (COVID-19), Neutrophils, animal diseases, viruses, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Common Cold, chemical and pharmacologic phenomena, Cross Reactions, Biology, Pediatrics, Virus, Interferon-gamma, Immune system, Humans, Child, Multidisciplinary, Innate immune system, SARS-CoV-2, Interleukin-17, COVID-19, Cross reactions, Viral Load, biochemical phenomena, metabolism, and nutrition, Immunity, Innate, Systemic Inflammatory Response Syndrome, Interferon Type I, Immunology, bacteria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a472418fec66483481c26aeaba7d255Test
https://doi.org/10.1038/d41586-021-02423-8Test