-
1
المؤلفون: Monika M Gladka, Andrew H. Baker
المصدر: Cardiovascular Research. 117:e46-e48
مصطلحات موضوعية: Vascular smooth muscle, Physiology, Genetic enhancement, Biology, medicine.disease_cause, Cell biology, Jumping, Genome editing, In vivo, Physiology (medical), medicine, Cardiology and Cardiovascular Medicine, Base (exponentiation), Hutchinson Gilford Progeria Syndrome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9b6d7ba446e451269cf91cbe2a129c25Test
https://doi.org/10.1093/cvr/cvab057Test -
2
المؤلفون: Ian R. Kill, Wendy Ofosu, Joanna M. Bridger, Craig S. Clements, Evgeny M. Makarov, David Tree, Christopher H. Eskiw, Mehmet U. Bikkul
المصدر: Biogerontology
مصطلحات موضوعية: 0301 basic medicine, Aging, N-acetyl cysteine, Farnesyltransferase, Hutchinson-Gilford Progeria Syndrome, Progerin, LMNA, zoledronic acid, 0302 clinical medicine, Progeria, Enzyme Inhibitors, Pravastatin, farnesyl transferase inhibitors, pravastatin, biology, integumentary system, Chemistry, Lamin Type A, embryonic structures, Mevalonate pathway, medicine.drug, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, Mevalonic Acid, Cell Line, 03 medical and health sciences, Internal lamin foci, medicine, Humans, Rapamycin, PI3K/AKT/mTOR pathway, Zoledronic acid, nuclear lamins, Hutchinson–Gilford progeria syndrome, rapamycin, Farnesyl transferase inhibitors, nutritional and metabolic diseases, medicine.disease, 030104 developmental biology, progerin, biology.protein, Cancer research, Nuclear lamins, Geriatrics and Gerontology, Gerontology, 030217 neurology & neurosurgery, Lamin
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6b2fd09330521c2ec71ca71051a6afTest
http://europepmc.org/articles/PMC6535420Test -
3
المؤلفون: Silvia Ortega-Gutiérrez, Beatriz Marcos-Ramiro, Jon Macicior
المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7190, p 7190 (2021)مصطلحات موضوعية: 0301 basic medicine, Aging, Pyridines, Review, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Lonafarnib, Biology (General), Hutchinson–Gilford progeria syndrome (HGPS), Spectroscopy, Cellular Senescence, Skin, Progeria, Mutation, integumentary system, rare diseases, Aging, Premature, General Medicine, Progerin, Lamin Type A, Computer Science Applications, Chemistry, Phenotype, 030220 oncology & carcinogenesis, Nuclear lamina, congenital, hereditary, and neonatal diseases and abnormalities, QH301-705.5, Context (language use), Biology, Catalysis, Inorganic Chemistry, Small Molecule Libraries, 03 medical and health sciences, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, lamin A, Cell Nucleus, Nuclear Lamina, Point mutation, Organic Chemistry, Laminopathies, Química orgánica, nutritional and metabolic diseases, progeria, Fibroblasts, medicine.disease, 030104 developmental biology, chemistry, progerin, Cancer research, Lamin
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb1b7093f85929d11daee5c183d56dcTest
http://europepmc.org/articles/PMC8267806Test -
4
المؤلفون: Wing-Fu Lai, Wing Tak Wong
المصدر: Aging Cell
مصطلحات موضوعية: 0301 basic medicine, Premature aging, Aging, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Laminopathy, Disease, Review, laminopathy, Biology, 03 medical and health sciences, 0302 clinical medicine, Progeria, Intervention (counseling), medicine, Humans, Intensive care medicine, Hutchinson–Gilford progeria syndrome, integumentary system, treatment, premature aging, Intervention design, nutritional and metabolic diseases, Cell Biology, Syndrome, medicine.disease, 030104 developmental biology, Physiological Aging, Disease Progression, Hutchinson Gilford Progeria Syndrome, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c822d7568f6bd2850914a2f77460542cTest
https://pubmed.ncbi.nlm.nih.gov/32596971Test -
5
المؤلفون: Paul Wanschoor, Simon Willaume, Pascale Bertrand, Emilie Rass, Paula Fontanilla-Ramirez, Angela Moussa
المصدر: Genes, Vol 12, Iss 552, p 552 (2021)
Genesمصطلحات موضوعية: 0301 basic medicine, Genome instability, Senescence, DNA Replication, cGAS-STING pathway, senescence, lcsh:QH426-470, DNA repair, DNA damage, Inflammation, Review, Biology, Genomic Instability, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Genetics, medicine, cancer, Animals, Humans, Genetics (clinical), aging, genome instability, DNA replication stress, Double Strand Break Repair, Lamins, Hutchinson-Gilford progeria syndrome, Cell biology, lcsh:Genetics, Oxidative Stress, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, double-strand break repair, medicine.symptom, DNA, Lamin, DNA Damage
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433a63d4abfad0bef94b2c07871f7669Test
https://pubmed.ncbi.nlm.nih.gov/33918867Test -
6
المؤلفون: Hanne Leysen, Jhana O. Hendrickx, Paula Santos-Otte, Stuart Maudsley, Jaana van Gastel, Bronwen Martin
المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1265-1277 (2019)مصطلحات موضوعية: Aging, Review Article, Disease, Aging disorders, Biochemistry, vascular smooth muscle cells, (VSMC), cyclin-dependent kinase inhibitor 1, (cdkn1A/p21), 0302 clinical medicine, Structural Biology, Hutchinson–Gilford progeria syndrome, (HGPS), purinergic receptors family, (P2Y), protein kinases, (PK), beta2-adrenergic receptor, (β2AR), Receptor, endothelial cell differentiation gene, (Edg), nuclear factor kappa-light-chain-enhancer of activated B cells, (NF- κβ), senescence associated secretory phenotype, (SASP), 0303 health sciences, Relaxin family receptor 3, (RXFP3), tumor suppressor gene PTEN, (PTEN), transcription factor E2F3, (E2F3), Computer Science Applications, Cell biology, retinoblastoma, (RB), Chemistry, 030220 oncology & carcinogenesis, G protein-coupled receptor kinase, (GRK), latent semantic indexing, (LSI), Lysophosphatidic acid, (LPA), G protein-coupled receptors (GPCRs), G protein-coupled receptor kinase interacting protein 2 (GIT2), mitogen-activated protein kinase, (MAPK), Regulator of G-protein signaling, (RGS), Engineering sciences. Technology, AT1R blockers, (ARB), Biotechnology, Cell signaling, lcsh:Biotechnology, renin-angiotensin system, (RAS), Biophysics, Cellular senescence, tumor suppressor protein 53, (p53), Biology, 03 medical and health sciences, Cell surface receptor, lcsh:TP248.13-248.65, angiotensin type 2 receptor, (AT2R), Genetics, G protein-coupled receptor kinase interacting protein 2, (GIT2), Ataxia telangiectasia mutated, (ATM), Angiotensin II, (Ang II), 030304 developmental biology, G protein-coupled receptor, inactive state, (R), angiotensin type 1 receptor, (AT1R), G protein-coupled receptors, (GPCRs), β-Arrestin, ADP-ribosylation factor GTPase-activating protein, (Arf-GAP), cyclin-dependent kinase 2, (CDK2), Apoptosis, transmembrane, (TM), stress-induced premature senescence, (SIPS), active state, (R*)
وصف الملف: pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df108c2d57f738f31f95e73a11100b3Test
https://doi.org/10.1016/j.csbj.2019.08.005Test -
7
المؤلفون: Gastone Castellani, Giovanna Lattanzi, Entele Gavoci, Isabella Zironi, Angela Virelli, Daniel Remondini, Fabrizio Amorini
المساهمون: Zironi, Isabella, Gavoçi, Entelë, Lattanzi, Giovanna, Virelli, Angela, Amorini, Fabrizio, Remondini, Daniel, Castellani, Gastone
المصدر: Aging (Albany NY)
مصطلحات موضوعية: 0301 basic medicine, Adult, BK channel, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, patch clamp, LMNA, 03 medical and health sciences, K current +, Young Adult, 0302 clinical medicine, Progeria, Gene expression, medicine, Cell Adhesion, Humans, Large-Conductance Calcium-Activated Potassium Channels, LMNA gene, Child, Aged, Cell Proliferation, cellular proliferation, Aged, 80 and over, biology, membrane channel, integumentary system, Chemistry, aging, Cell Membrane, nutritional and metabolic diseases, Cell Biology, Fibroblasts, medicine.disease, Progerin, Lamin Type A, K+ current, Potassium channel, Chromatin, Cell biology, membrane channels, 030104 developmental biology, Gene Expression Regulation, 030220 oncology & carcinogenesis, gene LMNA, biology.protein, Hutchinson-Gilford Progeria Syndrome (HGPS), Lamin, Research Paper
وصف الملف: ELETTRONICO
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70df7d2e68322cf0fb4ed63aa1545ca2Test
http://europepmc.org/articles/PMC6286842Test -
8
المؤلفون: Elin Tüksammel, Clotilde Wiel, Mark R. Philips, Ting Wang, Mohamed X. Ibrahim, Haidong Yao, Staffan Strömblad, Gwladys Revêchon, Muhammad Kashif, Jianjiang Hu, Maria Eriksson, Ian M. Ahearn, Yiran Liu, Martin O. Bergo, Xue Chen
مصطلحات موضوعية: Senescence, Cancer research, Biology, Small molecule, Hutchinson Gilford Progeria Syndrome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c8714222d18d7b1841bfe7780f20f834Test
https://doi.org/10.7554/elife.63284.sa2Test -
9
المؤلفون: Paolo Bianchini, Alberto Diaspro, Luca Pesce
المصدر: Methods in Cell Biology ISBN: 9780128208076
مصطلحات موضوعية: Nucleoplasmic reticulum, Nanotechnology, Biology, ExSTED, law.invention, 03 medical and health sciences, Optical microscope, law, Microscopy, Nup153, Nuclear pore, Nanoscopic scale, 030304 developmental biology, chemistry.chemical_classification, Cell Nucleus, 0303 health sciences, Biomolecule, Isotropy, STED microscopy, Nuclear lamina, Proteins, Hydrogels, Hutchinson-Gilford progeria syndrome, Nuclear pore complex, STED, chemistry, Nuclear Pore
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096b89e25fcc3eab6c576746c665bc81Test
http://hdl.handle.net/11567/1070216Test -
10
