نتائج البحث - "E Shelley Hwang"

1

Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

المصدر: Nature materials, vol 20, iss 4
Maller, O, Drain, A P, Barrett, A S, Borgquist, S, Ruffell, B, Zakharevich, I, Pham, T T, Gruosso, T, Kuasne, H, Lakins, J N, Acerbi, I, Barnes, J M, Nemkov, T, Chauhan, A, Gruenberg, J, Nasir, A, Bjarnadottir, O, Werb, Z, Kabos, P, Chen, Y-Y, Hwang, E S, Park, M, Coussens, L M, Nelson, A C, Hansen, K C & Weaver, V M 2021, ' Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression ', Nature Materials, vol. 20, no. 4, pp. 548-559 . https://doi.org/10.1038/s41563-020-00849-5Test
Nature materials

مصطلحات موضوعية: Breast Neoplasms/immunology, Biopsy, 02 engineering and technology, 01 natural sciences, Metastasis, Protein-Lysine 6-Oxidase, chemistry.chemical_compound, Tumor-Associated Macrophages, 2.1 Biological and endogenous factors, General Materials Science, Cancer, Tumor, biology, Chemistry, Tumor-Associated Macrophages/metabolism, Middle Aged, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Protein-Lysine 6-Oxidase/metabolism, Mechanics of Materials, cardiovascular system, Immunohistochemistry, Female, Collagen, 0210 nano-technology, Adult, Stromal cell, Lysyl hydroxylase, Stromal Cells/metabolism, Breast Neoplasms, Lysyl oxidase, macromolecular substances, 010402 general chemistry, Article, Cell Line, Stroma, Cell Line, Tumor, Collagen/metabolism, Breast Cancer, medicine, Humans, Nanoscience & Nanotechnology, Mechanical Engineering, technology, industry, and agriculture, General Chemistry, medicine.disease, 0104 chemical sciences, Hydroxylysine, biology.protein, Cancer research, Stromal Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b763b8a68e3e138bcaa445e6a01a159Test
https://doi.org/10.1038/s41563-020-00849-5Test

2

The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

المؤلفون: Orit Rozenblatt-Rosen, Aviv Regev, Philipp Oberdoerffer, Tal Nawy, Anna Hupalowska, Jennifer E. Rood, Orr Ashenberg, Ethan Cerami, Robert J. Coffey, Emek Demir, Li Ding, Edward D. Esplin, James M. Ford, Jeremy Goecks, Sharmistha Ghosh, Joe W. Gray, Justin Guinney, Sean E. Hanlon, Shannon K. Hughes, E. Shelley Hwang, Christine A. Iacobuzio-Donahue, Judit Jané-Valbuena, Bruce E. Johnson, Ken S. Lau, Tracy Lively, Sarah A. Mazzilli, Dana Pe’er, Sandro Santagata, Alex K. Shalek, Denis Schapiro, Michael P. Snyder, Peter K. Sorger, Avrum E. Spira, Sudhir Srivastava, Kai Tan, Robert B. West, Elizabeth H. Williams, Denise Aberle, Samuel I. Achilefu, Foluso O. Ademuyiwa, Andrew C. Adey, Rebecca L. Aft, Rachana Agarwal, Ruben A. Aguilar, Fatemeh Alikarami, Viola Allaj, Christopher Amos, Robert A. Anders, Michael R. Angelo, Kristen Anton, Jon C. Aster, Ozgun Babur, Amir Bahmani, Akshay Balsubramani, David Barrett, Jennifer Beane, Diane E. Bender, Kathrin Bernt, Lynne Berry, Courtney B. Betts, Julie Bletz, Katie Blise, Adrienne Boire, Genevieve Boland, Alexander Borowsky, Kristopher Bosse, Matthew Bott, Ed Boyden, James Brooks, Raphael Bueno, Erik A. Burlingame, Qiuyin Cai, Joshua Campbell, Wagma Caravan, Hassan Chaib, Joseph M. Chan, Young Hwan Chang, Deyali Chatterjee, Ojasvi Chaudhary, Alyce A. Chen, Bob Chen, Changya Chen, Chia-hui Chen, Feng Chen, Yu-An Chen, Milan G. Chheda, Koei Chin, Roxanne Chiu, Shih-Kai Chu, Rodrigo Chuaqui, Jaeyoung Chun, Luis Cisneros, Graham A. Colditz, Kristina Cole, Natalie Collins, Kevin Contrepois, Lisa M. Coussens, Allison L. Creason, Daniel Crichton, Christina Curtis, Tanja Davidsen, Sherri R. Davies, Ino de Bruijn, Laura Dellostritto, Angelo De Marzo, David G. DeNardo, Dinh Diep, Sharon Diskin, Xengie Doan, Julia Drewes, Stephen Dubinett, Michael Dyer, Jacklynn Egger, Jennifer Eng, Barbara Engelhardt, Graham Erwin, Laura Esserman, Alex Felmeister, Heidi S. Feiler, Ryan C. Fields, Stephen Fisher, Keith Flaherty, Jennifer Flournoy, Angelo Fortunato, Allison Frangieh, Jennifer L. Frye, Robert S. Fulton, Danielle Galipeau, Siting Gan, Jianjiong Gao, Long Gao, Peng Gao, Vianne R. Gao, Tim Geiger, Ajit George, Gad Getz, Marios Giannakis, David L. Gibbs, William E. Gillanders, Simon P. Goedegebuure, Alanna Gould, Kate Gowers, William Greenleaf, Jeremy Gresham, Jennifer L. Guerriero, Tuhin K. Guha, Alexander R. Guimaraes, David Gutman, Nir Hacohen, Sean Hanlon, Casey R. Hansen, Olivier Harismendy, Kathleen A. Harris, Aaron Hata, Akimasa Hayashi, Cody Heiser, Karla Helvie, John M. Herndon, Gilliam Hirst, Frank Hodi, Travis Hollmann, Aaron Horning, James J. Hsieh, Shannon Hughes, Won Jae Huh, Stephen Hunger, Shelley E. Hwang, Heba Ijaz, Benjamin Izar, Connor A. Jacobson, Samuel Janes, Reyka G. Jayasinghe, Lihua Jiang, Brett E. Johnson, Bruce Johnson, Tao Ju, Humam Kadara, Klaus Kaestner, Jacob Kagan, Lukas Kalinke, Robert Keith, Aziz Khan, Warren Kibbe, Albert H. Kim, Erika Kim, Junhyong Kim, Annette Kolodzie, Mateusz Kopytra, Eran Kotler, Robert Krueger, Kostyantyn Krysan, Anshul Kundaje, Uri Ladabaum, Blue B. Lake, Huy Lam, Rozelle Laquindanum, Ashley M. Laughney, Hayan Lee, Marc Lenburg, Carina Leonard, Ignaty Leshchiner, Rochelle Levy, Jerry Li, Christine G. Lian, Kian-Huat Lim, Jia-Ren Lin, Yiyun Lin, Qi Liu, Ruiyang Liu, William J.R. Longabaugh, Teri Longacre, Cynthia X. Ma, Mary Catherine Macedonia, Tyler Madison, Christopher A. Maher, Anirban Maitra, Netta Makinen, Danika Makowski, Carlo Maley, Zoltan Maliga, Diego Mallo, John Maris, Nick Markham, Jeffrey Marks, Daniel Martinez, Robert J. Mashl, Ignas Masilionais, Jennifer Mason, Joan Massagué, Pierre Massion, Marissa Mattar, Richard Mazurchuk, Linas Mazutis, Eliot T. McKinley, Joshua F. McMichael, Daniel Merrick, Matthew Meyerson, Julia R. Miessner, Gordon B. Mills, Meredith Mills, Suman B. Mondal, Motomi Mori, Yuriko Mori, Elizabeth Moses, Yael Mosse, Jeremy L. Muhlich, George F. Murphy, Nicholas E. Navin, Michel Nederlof, Reid Ness, Stephanie Nevins, Milen Nikolov, Ajit Johnson Nirmal, Garry Nolan, Edward Novikov, Brendan O’Connell, Michael Offin, Stephen T. Oh, Anastasiya Olson, Alex Ooms, Miguel Ossandon, Kouros Owzar, Swapnil Parmar, Tasleema Patel, Gary J. Patti, Itsik Pe'er, Tao Peng, Daniel Persson, Marvin Petty, Hanspeter Pfister, Kornelia Polyak, Kamyar Pourfarhangi, Sidharth V. Puram, Qi Qiu, Álvaro Quintanal-Villalonga, Arjun Raj, Marisol Ramirez-Solano, Rumana Rashid, Ashley N. Reeb, Mary Reid, Adam Resnick, Sheila M. Reynolds, Jessica L. Riesterer, Scott Rodig, Joseph T. Roland, Sonia Rosenfield, Asaf Rotem, Sudipta Roy, Charles M. Rudin, Marc D. Ryser, Maria Santi-Vicini, Kazuhito Sato, Deborah Schrag, Nikolaus Schultz, Cynthia L. Sears, Rosalie C. Sears, Subrata Sen, Triparna Sen, Alex Shalek, Jeff Sheng, Quanhu Sheng, Kooresh I. Shoghi, Martha J. Shrubsole, Yu Shyr, Alexander B. Sibley, Kiara Siex, Alan J. Simmons, Dinah S. Singer, Shamilene Sivagnanam, Michal Slyper, Artem Sokolov, Sheng-Kwei Song, Austin Southard-Smith, Avrum Spira, Janet Stein, Phillip Storm, Elizabeth Stover, Siri H. Strand, Timothy Su, Damir Sudar, Ryan Sullivan, Lea Surrey, Mario Suvà, Nadezhda V. Terekhanova, Luke Ternes, Lisa Thammavong, Guillaume Thibault, George V. Thomas, Vésteinn Thorsson, Ellen Todres, Linh Tran, Madison Tyler, Yasin Uzun, Anil Vachani, Eliezer Van Allen, Simon Vandekar, Deborah J. Veis, Sébastien Vigneau, Arastoo Vossough, Angela Waanders, Nikhil Wagle, Liang-Bo Wang, Michael C. Wendl, Robert West, Chi-yun Wu, Hao Wu, Hung-Yi Wu, Matthew A. Wyczalkowski, Yubin Xie, Xiaolu Yang, Clarence Yapp, Wenbao Yu, Yinyin Yuan, Dadong Zhang, Kun Zhang, Mianlei Zhang, Nancy Zhang, Yantian Zhang, Yanyan Zhao, Daniel Cui Zhou, Zilu Zhou, Houxiang Zhu, Qin Zhu, Xiangzhu Zhu, Yuankun Zhu, Xiaowei Zhuang

المصدر: Cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ea82738e14282269df985158663c08Test
https://doi.org/10.1016/j.cell.2020.03.053Test

3

Minimal barriers to invasion during human colorectal tumor growth

المؤلفون: Inmaculada C. Sorribes, Marc D. Ryser, Timothy Hardman, E. Shelley Hwang, Carlo C. Maley, Lorraine M. King, Darryl Shibata, Jeffrey R. Marks, Allison Hall, Sergei Tatishchev, Diego Mallo

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091fb3ea9f6e2aa62900f8fa63cfa6f5Test
http://link.springer.com/article/10.1038/s41467-020-14908-7Test

4

Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler

المصدر: Cancers
Cancers, Vol 13, Iss 4456, p 4456 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb0340db6acd012e373b33faef52ee1Test
http://europepmc.org/articles/PMC8431590Test

5

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

المؤلفون: Chunfang Zhu, Siri H Strand, Daisy Yi Ding, Kristalyn K. Gallagher, Jose A. Seoane, Lunden A Simpson, Luis Cisneros, Allison Hall, Kornelia Polyak, Belén Rivero-Gutiérrez, Sucheta Srivastava, Kathleen E. Houlahan, Shirley Zhu, Cody Straub, Aziz Khan, Dadong Zhang, Magdalena Matusiak, Deborah J. Veis, Alastair M. Thompson, Mark R. Kilgore, Julie R. Nangia, Jeffrey R. Marks, Jennifer F. Tseng, Robert B. West, Timothy Hardman, Angela DeMichele, Graham A. Colditz, Anna Maria Storniolo, Tari King, Kouros Owzar, Jen Tappenden, E. Shelley Hwang, Robert M. Angelo, Joanna Lee, Shu Jiang, Sushama Varma, Carlo C. Maley, Priscilla F. McAuliffe, Lauren Anderson, Shi Wei, Katherine DeSchryver, Robert Tibshirani, Robyn Burns, Gaorav P. Gupta, Sujay Vennam, Bryan Harmon, Lorraine M. King, Christina Curtis, Jason K. Wang, Jingqin Luo, Tyler Risom, Fergus J. Couch

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Spatially resolved, Disease, Ductal carcinoma, Biology, medicine.disease, Protein expression, Transcriptome, Human tumor, Breast cancer, Internal medicine, medicine, Stage (cooking), skin and connective tissue diseases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d756705ca8fdb45c948c692a33a65913Test
https://doi.org/10.1101/2021.06.16.448585Test

6

A new method to accurately identify single nucleotide variants using small FFPE breast samples

المؤلفون: Angelo Fortunato, E. Shelley Hwang, Allison Hall, Diego Mallo, Joseph Y. Lo, Jeffrey R. Marks, Lorraine M. King, Carlo C. Maley, Timothy Hardman, Shawn M. Rupp

المصدر: Briefings in Bioinformatics

مصطلحات موضوعية: AcademicSubjects/SCI01060, DCIS, Breast Neoplasms, Computational biology, Biology, Genome, Polymorphism, Single Nucleotide, DNA sequencing, Workflow, chemistry.chemical_compound, Genetic Heterogeneity, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, medicine, Breast ductal carcinoma, Biomarkers, Tumor, Humans, Sign test, Nucleotide, Genetic Testing, Indel, Molecular Biology, Exome, Exome sequencing, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Histopathological analysis, Cancer, Computational Biology, High-Throughput Nucleotide Sequencing, DNA, Neoplasm, Ductal carcinoma, medicine.disease, Invasive ductal carcinoma, chemistry, NGS, 030220 oncology & carcinogenesis, Mutation, Problem Solving Protocol, Female, heterogeneity, DNA, exome, Information Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fef238a633ec59b8d4210f264d4463Test
https://doi.org/10.1093/bib/bbab221Test

7

Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling

المؤلفون: Smita K. Nair, E. Shelley Hwang, Zachary P. McKay, Jonathan P. Kastan, Malte Mohme, Michael C. Brown, David M. Ashley, Matthias Gromeier, Mubeen Mosaheb, Yuanfan Yang, Darell D. Bigner, Eda K. Holl, Georgia M. Beasley

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

مصطلحات موضوعية: 0301 basic medicine, Interferon-Induced Helicase, IFIH1, Cancer therapy, viruses, medicine.medical_treatment, General Physics and Astronomy, Priming (immunology), CD8-Positive T-Lymphocytes, Mice, 0302 clinical medicine, Tumor Microenvironment, Melanoma, Mice, Knockout, Oncolytic Virotherapy, Multidisciplinary, Pattern recognition receptor, NF-kappa B, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Interferon Type I, Tumour immunology, Female, Immunotherapy, Signal Transduction, Science, T cell, Breast Neoplasms, Biology, Protein Serine-Threonine Kinases, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, medicine, Animals, Humans, Virotherapy, Tumor microenvironment, Innate immune system, General Chemistry, biochemical phenomena, metabolism, and nutrition, Th1 Cells, Immunity, Innate, Oncolytic virus, Mice, Inbred C57BL, 030104 developmental biology, Cancer research, Interferon Regulatory Factor-3

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994a4cb6b5682434eebe1aa397dfa3cbTest
http://europepmc.org/articles/PMC7994570Test

8

Molecular determinants of post-mastectomy breast cancer recurrence

المصدر: npj Breast Cancer, Vol 4, Iss 1, Pp 1-9 (2018)
NPJ Breast Cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4ea39f5e295a10a1d6ac149ca4571bTest
http://link.springer.com/article/10.1038/s41523-018-0089-zTest

9

Minimal Barriers to Invasion During Human Colorectal Tumor Growth

المؤلفون: Allison Hall, Marc D. Ryser, E. Shelley Hwang, Darryl Shibata, Lorraine M. King, Inmaculada C. Sorribes, Timothy Hardman, Diego Mallo, Carlo C. Maley, Jeffrey R. Marks

مصطلحات موضوعية: 0303 health sciences, Adenoma, Colorectal cancer, Biology, medicine.disease, Somatic evolution in cancer, Phenotype, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Cancer research, medicine, Colorectal tumor, Microdissection, 030304 developmental biology, Colorectal Tumors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276d46a0b08374e2143035b423bdec84Test
https://doi.org/10.1101/842203Test

10

Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers and therapeutic targets

المصدر: Cassetta, L, Fragkogianni, S, Sims, A H, Swierczak, A, Forrester, L M, Zhang, H, Soong, D, Cotechini, T, Anur, P, Lin, E, Fidanza, A, Lopez Yrigoyen, M, Millar, M, Urman, A, Ai, Z, Spellman, P T, Hwang, E S, Dixon, J M, Wiechmann, L, Coussens, L M, W. Smith, H & Pollard, J W 2019, ' Human tumor-associated macrophage and monocyte transcriptional landscapes reveal cancer-specific reprogramming, biomarkers and therapeutic targets ', Cancer Cell, vol. 35, no. 4, pp. 588-602.e10 . https://doi.org/10.1016/j.ccell.2019.02.009Test

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Transcription, Genetic, Sialic Acid Binding Ig-like Lectin 1, THP-1 Cells, Induced Pluripotent Stem Cells, Antineoplastic Agents, Breast Neoplasms, Biology, CCL8, Monocytes, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, stomatognathic system, Paracrine Communication, Biomarkers, Tumor, Tumor Microenvironment, medicine, Chemokine CCL8, Humans, Macrophage, Molecular Targeted Therapy, skin and connective tissue diseases, Tumor microenvironment, Macrophage Colony-Stimulating Factor, Macrophages, Monocyte, Endometrial cancer, Cancer, Cell Biology, Cellular Reprogramming, medicine.disease, Endometrial Neoplasms, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Tumor necrosis factor alpha, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa503d0d0fba4ad11496db553c445bcTest
https://hdl.handle.net/20.500.11820/63a217b4-34e8-4d02-bf6d-794aa17da8dfTest

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