المؤلفون: Maurits L. van Montfoort, Daniel J. Vis, Kees Hendricksen, Nick van Dijk, Laura A. Smit, Michiel S. van der Heijden, Henk G. van der Poel, Maries van den Broek, Christian U. Blank, Annemarie Bruining, Yoni Lubeck, Lodewyk F. A. Wessels, Dennis Peters, Pia Kvistborg, Karina Silina, Ton N. Schumacher, Charlotte van Rooijen, Karolina Sikorska, Erik Hooijberg, Annegien Broeks, Bas W.G. van Rhijn, Alberto Gil-Jimenez, Jeantine M de Feijter, Thierry N. Boellaard

المساهمون: University of Zurich, van der Heijden, Michiel S, Graduate School

المصدر: Nature medicine, 26(12), 1839-1844. Nature Publishing Group

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, medicine.medical_treatment, Programmed Cell Death 1 Receptor, 610 Medicine & health, Ipilimumab, 10263 Institute of Experimental Immunology, Gastroenterology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, 1300 General Biochemistry, Genetics and Molecular Biology, Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Clinical endpoint, Humans, Medicine, CTLA-4 Antigen, Stage (cooking), Adverse effect, Aged, Neoplasm Staging, business.industry, Antibodies, Monoclonal, General Medicine, Immunotherapy, Middle Aged, Clinical trial, Nivolumab, 030104 developmental biology, 030220 oncology & carcinogenesis, Monoclonal, 570 Life sciences, biology, Female, Urothelium, business, medicine.drug

وصف الملف: 2020_van_Dijk_Nat_Med.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0413d513e2c90df2d190163c39a4236dTest
http://www.scopus.com/inward/record.url?scp=85092396181&partnerID=8YFLogxKTest

المؤلفون: Elisabeth G.E. de Vries, Christian U. Blank, John B. A. G. Haanen, Guus F. Rimmelzwaan, Egbert F. Smit, Cecile A C M van Els, Astrid A M van der Veldt, Marion Koopmans, Nynke Y. Rots, Rudolf S N Fehrmann, T. Jeroen N. Hiltermann, Mathilde Jalving, Corine H. GeurtsvanKessel, Sjoukje F. Oosting, Anke Huckriede, Pia Kvistborg, Debbie van Baarle, Valery E E P Lemmens, Anne-Marie C. Dingemans

المساهمون: Medical Oncology, Radiology & Nuclear Medicine, Pulmonary Medicine, Virology, Public Health, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Targeted Gynaecologic Oncology (TARGON), Translational Immunology Groningen (TRIGR), Microbes in Health and Disease (MHD)

المصدر: Nature Medicine, 27(4), 568-569. Nature Publishing Group
Nature Medicine. Nature Publishing Group

مصطلحات موضوعية: 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), biology, business.industry, MEDLINE, Cancer, General Medicine, medicine.disease, Virology, General Biochemistry, Genetics and Molecular Biology, Vaccination, Multicenter study, SDG 3 - Good Health and Well-being, biology.protein, Medicine, Antibody, Prospective cohort study, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f05c83fbac1ec5a4eb2925dda100dfTest
https://pure.eur.nl/en/publications/2b70ca55-2c99-47c8-9c5d-c1e6e0b95813Test

المؤلفون: Christian U. Blank, Fabienne Verburg, Daniel S. Peeper, Disha Rao, Ruben Lacroix, Kathrin Renner

المصدر: Cancer immunology, immunotherapy : CII. 70(9)

مصطلحات موضوعية: Cancer Research, Nutrient depletion, Immunology, chemical and pharmacologic phenomena, Oxidative phosphorylation, Biology, medicine.disease_cause, T-Lymphocytes, Regulatory, Immunomodulation, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Immunity, T-Lymphocyte Subsets, Neoplasms, medicine, Tumor Microenvironment, Immunology and Allergy, Animals, Humans, Metabolomics, Hypoxia, Effector, Acidity, hemic and immune systems, Hypoxia (medical), Mitochondria, Treg, Metabolism, Oncology, Oxidative stress, Cancer cell, Cancer research, Metabolome, Disease Susceptibility, medicine.symptom, Energy Metabolism, Glycolysis, Metabolic profile, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c48eb6f74c401db2072a46b0438b446Test
https://pubmed.ncbi.nlm.nih.gov/33576875Test

المؤلفون: Christian U. Blank, Daniela S. Thommen, Judith M. Versluis

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, medicine.medical_treatment, Immunology, Context (language use), Review, Translational Research, Biomedical, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Internal medicine, Programmed cell death 1, melanoma, medicine, Humans, Immunology and Allergy, Precision Medicine, RC254-282, Pharmacology, biology, business.industry, Melanoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunotherapy, medicine.disease, Neoadjuvant Therapy, Treatment efficacy, Cancer treatment, Human tumor, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, translational medical research, biology.protein, Molecular Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe6d45de1c52a82b9d33dd6191a7069Test
https://jitc.bmj.com/content/8/2/e001352.fullTest

المؤلفون: Adina Weinberger, Ron Shaoul, Morgan G. I. Langille, Alexandria P. Cogdill, Giuseppe Mallel, Talia Golan, Anat Ronai, Arnon Meltser, Vancheswaran Gopalakrishnan, Christian U. Blank, Jennifer A. Wargo, Einav Yehuda-Shnaidman, Tali Dadosh, Maya Dadiani, Daniel S. Peeper, Merav Rokah, Alon Ben-Nun, Reetakshi Arora, Elinor Gigi, Aviram Nissan, Keren Levanon, Zachary A. Cooper, Tatiana Dorfman, Gavin M. Douglas, Iris Kamer, Gabriel Ologun, Ilana Livyatan, Zvi R. Cohen, Iris Barshack, Noam Shental, Elisa A. Rozeman, Nicola Baldini, Einav Nili Gal-Yam, Nancy Gavert, Shlomit Yust-Katz, Ran Kremer, Eran Segal, Ravid Straussman, Roi Weiser, Yaara Zwang, Yuval Bussi, Hagit Shapira, Tehila Atlan, Dan J. Raz, Amnon Amit, Smadar Levin-Zaidman, Bella Kaufman, Aviva Rotter-Maskowitz, Keren Bahar-Shany, Tali Siegal, Abdul Wadud Khan, Judith Sandbank, Deborah Nejman, Gili Perry, Jair Bar, Maya Lotan-Pompan, Sofia Avnet, Ofra Golani, Garold Fuks, Leore T. Geller, Sagi Harnof

المساهمون: Nejman D., Livyatan I., Fuks G., Gavert N., Zwang Y., Geller L.T., Rotter-Maskowitz A., Weiser R., Mallel G., Gigi E., Meltser A., Douglas G.M., Kamer I., Gopalakrishnan V., Dadosh T., Levin-Zaidman S., Avnet S., Atlan T., Cooper Z.A., Arora R., Cogdill A.P., Khan M.A.W., Ologun G., Bussi Y., Weinberger A., Lotan-Pompan M., Golani O., Perry G., Rokah M., Bahar-Shany K., Rozeman E.A., Blank C.U., Ronai A., Shaoul R., Amit A., Dorfman T., Kremer R., Cohen Z.R., Harnof S., Siegal T., Yehuda-Shnaidman E., Gal-Yam E.N., Shapira H., Baldini N., Langille M.G.I., Ben-Nun A., Kaufman B., Nissan A., Golan T., Dadiani M., Levanon K., Bar J., Yust S., Barshack I., Peeper D.S., Raz D.J., Segal E., Wargo J.A., Sandbank J., Shental N., Straussman R.

المصدر: Science

مصطلحات موضوعية: 0301 basic medicine, Male, Colon, Macrophage, medicine.medical_treatment, Biology, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, RNA, Ribosomal, 16S, medicine, Microbiome, Breast, Lung, Multidisciplinary, Bacteria, Melanoma, Intracellular parasite, Microbiota, Ovary, Cancer, Immunotherapy, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Neoplasm, Female, Pancreas, Human

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c3a1966e5196491836aaf3aaf203f3Test
http://hdl.handle.net/11585/780581Test

المؤلفون: Guangchun Han, Deborah A. Ledesma, Wenbin Liu, Jeffrey E. Lee, Michael T. Tetzlaff, Christine N. Spencer, Michael A. Davies, Vancheswaran Gopalakrishnan, Oscar Krijgsman, Daniel S. Peeper, Reetakshi Arora, Christian U. Blank, James P. Allison, Catherine Sautès-Fridman, Roberta Zapassodi, Sangeetha M. Reddy, Alexander J. Lazar, Raghu Kalluri, Wolf H. Fridman, Hao Zhao, Lisa H. Butterfield, Keren Yizhak, Lauren E. Haydu, Elisa A. Rozeman, Jennifer A. Wargo, Pierre Olivier Gaudreau, Fernanda G. Kugeratski, Alexandre Reuben, Valerie S. LeBleu, Jianjun Gao, Rafet Basar, Beth A. Helmink, Emily Z. Keung, Hussein Abdul-Hassan Tawbi, Padmanee Sharma, Alex P. Cogdill, Linghua Wang, Disha Rao, Kevin M. McBride, Patrick Hwu, Ton N. Schumacher, Monika A. Zelazowska, Elizabeth M. Burton, Rodabe N. Amaria, Moshe Sade-Feldman, Florent Petitprez, Sapna Pradyuman Patel, Yuanxin Xi, Anthony Lucci, Nir Hacohen, Jorge Blando, Shaojun Zhang, Katayoun Rezvani, Rohit Thakur, Scott E. Woodman, SuFey Ong, Michael Bailey, Sarah Warren, Courtney W. Hudgens, Jeffrey E. Gershenwald

المساهمون: The University of Texas M.D. Anderson Cancer Center [Houston], Massachusetts General Hospital [Boston], School of Engineering [Edinburgh], University of Edinburgh, Memorial Sloane Kettering Cancer Center [New York], Netherlands Cancer Institute (NKI), Antoni van Leeuwenhoek Hospital, University of Pittsburgh (PITT), Pennsylvania Commonwealth System of Higher Education (PCSHE), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Gestionnaire, Hal Sorbonne Université

المصدر: Nature
Nature, Nature Publishing Group, 2020, 577 (7791), pp.549-555. ⟨10.1038/s41586-019-1922-8⟩
Nature, vol 577, iss 7791

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Mass Spectrometry, 0302 clinical medicine, Cancer immunotherapy, Immunologic, Receptors, RNA-Seq, Receptors, Immunologic, Neoplasm Metastasis, Melanoma, Cancer, B-Lymphocytes, Tumor, Multidisciplinary, Prognosis, 3. Good health, [SDV] Life Sciences [q-bio], Gene Expression Regulation, Neoplastic, Phenotype, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunotherapy, Single-Cell Analysis, Stromal cell, General Science & Technology, T cell, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, Article, Vaccine Related, 03 medical and health sciences, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, Biomarkers, Tumor, Genetics, medicine, Humans, Carcinoma, Renal Cell, B cell, Neoplastic, Carcinoma, Follicular, Renal Cell, Dendritic Cells, Cell Cycle Checkpoints, medicine.disease, Immune checkpoint, Clone Cells, Tertiary Lymphoid Structures, 030104 developmental biology, Gene Expression Regulation, Cancer research, Immunization, Transcriptome, Immunologic Memory, Dendritic Cells, Follicular, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be208e7a5506de19270310bdcd5f46c7Test
https://hal.sorbonne-universite.fr/hal-02456277Test

المؤلفون: Arlene H. Sharpe, Andrea Schietinger, Anjana Rao, Dietmar Zehn, Axel Kallies, Christian U. Blank, E. John Wherry, Werner Held, Rachel C. Lynn, Patrick G. Hogan, Pamela L. Schwartzberg, Ton N. Schumacher, Mary Philip, Enrico Lugli, Daniel E. Speiser, Benjamin Youngblood, Nicholas P. Restifo, W. Nicholas Haining

المصدر: Nat Rev Immunol
Nature reviews. Immunology, vol. 19, no. 11, pp. 665-674
Nature Reviews Immunology

مصطلحات موضوعية: 0301 basic medicine, History, T cell, medicine.medical_treatment, T-Lymphocytes, Population, Programmed Cell Death 1 Receptor, Biology, medicine.disease_cause, Infections, Article, Education, Autoimmunity, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Epigenetics, Hepatocyte Nuclear Factor 1-alpha, education, education.field_of_study, Effector, High Mobility Group Proteins, Immunotherapy, 3. Good health, Computer Science Applications, Chronic infection, 030104 developmental biology, medicine.anatomical_structure, Immunology, Memory T cell, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369ccb4fe5a58ae1653c78fa64943e41Test
https://pubmed.ncbi.nlm.nih.gov/31570879Test

المؤلفون: Thijo J N Hiltermann, T. Westphal, Nynke Y. Rots, Christian U. Blank, G. den Hartog, Marion Koopmans, Mathilde Jalving, Egbert F. Smit, A.A.M. Van der Veldt, M. van der Heiden, Sjoukje F. Oosting, Anne Marie C. Dingemans, J.B.A.G. Haanen, C. A. van Els, R van Binnendijk, A. Battacharya, D. van Baarle, Rudolf S N Fehrmann, E.G.E. de Vries, Corine H. GeurtsvanKessel

المصدر: Annals of Oncology

مصطلحات موضوعية: medicine.medical_specialty, biology, business.industry, medicine.medical_treatment, Cancer, Hematology, Immunotherapy, SARS-CoV-2 and cancer, medicine.disease, Vaccination, Clinical trial, Oncology, Internal medicine, Cohort, medicine, biology.protein, Clinical endpoint, Antibody, Adverse effect, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121cc447a79d85b059a330aa8ead3cabTest
http://europepmc.org/articles/PMC8454422Test

المؤلفون: Daniel S. Peeper, Christian U. Blank, Hans W.M. Niessen, Julia Boshuizen, Thomas Kuilman, Aida Shahrabi, Ji Ying Song, Xiangjun Kong, Kristel Kemper, Marnix H Geukes Foppen, Elisa A. Rozeman

المساهمون: CCA - Cancer biology and immunology, AGEM - Digestive immunity, ACS - Heart failure & arrhythmias, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Cardio-thoracic surgery, Pathology

المصدر: Nature, 550(7675), 270-274. Nature Publishing Group
Nature
Kong, X, Kuilman, T, Shahrabi, A, Boshuizen, J, Kemper, K, Song, J Y, Niessen, H W M, Rozeman, E A, Foppen, M H G, Blank, C U & Peeper, D S 2017, ' Cancer drug addiction is relayed by an ERK2-dependent phenotype switch ', Nature, vol. 550, no. 7675, pp. 270-274 . https://doi.org/10.1038/nature24037Test

مصطلحات موضوعية: 0301 basic medicine, Proto-Oncogene Proteins B-raf, Epithelial-Mesenchymal Transition, Lung Neoplasms, JUNB, MAP Kinase Signaling System, Dacarbazine, Antineoplastic Agents, Biology, Pharmacology, Receptor tyrosine kinase, Article, 03 medical and health sciences, Mice, Cell Line, Tumor, medicine, Animals, Humans, Epithelial–mesenchymal transition, Molecular Targeted Therapy, Melanoma, Gene Editing, Mice, Knockout, Mitogen-Activated Protein Kinase 1, Microphthalmia-Associated Transcription Factor, Multidisciplinary, Cell Death, medicine.disease, Microphthalmia-associated transcription factor, 3. Good health, 030104 developmental biology, Phenotype, Drug Resistance, Neoplasm, Cancer cell, biology.protein, Female, CRISPR-Cas Systems, Reprogramming, medicine.drug, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df46b5ac7614ee892024f1d1e15da0caTest
https://doi.org/10.1038/nature24037Test

المؤلفون: Christian U. Blank, Saskia A C Luelmo, Marloes S. van Kester, Maarten H. Vermeer, Remco van Doorn

المصدر: JAAD Case Reports

مصطلحات موضوعية: MAPK/ERK pathway, Sorafenib, FGFR, fibroblast growth factor receptor, VEGF receptors, Case Report, Dermatology, BRAF, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, vascular endothelial growth factor receptors, Psoriasis, medicine, kinase inhibitors, VEGFR, vascular endothelial growth factor receptors, biology, EGFR, the epidermal growth factor receptor, business.industry, psoriasis, medicine.disease, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, Mitogen-activated protein kinase, biology.protein, Cancer research, sorafenib, business, MAPK, mitogen-activated protein kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6257b435e2cd7ccfc79bee27a5ee7bTest
http://europepmc.org/articles/PMC6250899Test