المؤلفون: Joshua M. Weiss, Miranda V. Hunter, Nelly M. Cruz, Arianna Baggiolini, Mohita Tagore, Yilun Ma, Sandra Misale, Michelangelo Marasco, Theresa Simon-Vermot, Nathaniel R. Campbell, Felicity Newell, James S. Wilmott, Peter A. Johansson, John F. Thompson, Georgina V. Long, John V. Pearson, Graham J. Mann, Richard A. Scolyer, Nicola Waddell, Emily D. Montal, Ting-Hsiang Huang, Philip Jonsson, Mark T.A. Donoghue, Christopher C. Harris, Barry S. Taylor, Tianhao Xu, Ronan Chaligné, Pavel V. Shliaha, Ronald Hendrickson, Achim A. Jungbluth, Cecilia Lezcano, Richard Koche, Lorenz Studer, Charlotte E. Ariyan, David B. Solit, Jedd D. Wolchok, Taha Merghoub, Neal Rosen, Nicholas K. Hayward, Richard M. White

المصدر: Weiss, J M, Hunter, M V, Cruz, N M, Baggiolini, A, Tagore, M, Ma, Y, Misale, S, Marasco, M, Simon-Vermot, T, Campbell, N R, Newell, F, Wilmott, J S, Johansson, P A, Thompson, J F, Long, G V, Pearson, J V, Mann, G J, Scolyer, R A, Waddell, N, Montal, E D, Huang, T H, Jonsson, P, Donoghue, M T A, Harris, C C, Taylor, B S, Xu, T, Chaligné, R, Shliaha, P V, Hendrickson, R, Jungbluth, A A, Lezcano, C, Koche, R, Studer, L, Ariyan, C E, Solit, D B, Wolchok, J D, Merghoub, T, Rosen, N, Hayward, N K & White, R M 2022, ' Anatomic position determines oncogenic specificity in melanoma ', Nature, vol. 604, pp. 354-361 . https://doi.org/10.1038/s41586-022-04584-6Test
Nature

مصطلحات موضوعية: Skin Neoplasms, Transcription, Genetic, Carcinogenesis, Cell of origin, Biology, Article, Zebrafish/genetics, Animals, Genetically Modified, chemistry.chemical_compound, Skin Neoplasms/genetics, Melanoma/pathology, medicine, Animals, Humans, skin and connective tissue diseases, Melanoma, Gene, Zebrafish, Tropism, Multidisciplinary, Oncogenes/genetics, integumentary system, Foot, Oncogenes, medicine.disease, Hand, CRKL, chemistry, Nails, Cutaneous melanoma, Rna profiling, Cancer research, Carcinogenesis/genetics, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b39395de5cccb872bc76acd0f99b36dTest
https://portal.findresearcher.sdu.dk/da/publications/fc93f265-733a-47a2-81d0-e175a3bb1f60Test

المؤلفون: Nura Lutfi, Julian E. Sale, Matilde Murga, Lluis Colomo, Talia Velasco-Hernandez, Carlos Martinez, Ramon Gimeno, Françoise Dantzer, Gaël Roué, Anna Bigas, José Yélamos, Coral Ampurdanés, Guillaume Guilbaud, Oscar Fernandez-Capetillo, Violeta García-Hernández, Juan Martín-Caballero, Pilar Navarro, Sarah Bonnin, Pablo Menendez, Miguel Galindo-Campos

المساهمون: Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS), Ministerio de Industria y Competitividad (España), Ministerio de Ciencia e Innovación (España), Fundación Científica Asociación Española Contra el Cáncer, Medical Research Council (UK), Laboratory of Excellence of Biology for Psychiatry (France), Université de Strasbourg, Centre National de la Recherche Scientifique (France), Instituto de Salud Carlos III, European Commission, Generalitat de Catalunya, Centres de Recerca de Catalunya, Josep Carreras Leukemia Foundation, Fundación Unoentrecienmil, Marie Curie International Incoming Fellowship

المصدر: Blood
Blood, American Society of Hematology, In press, ⟨10.1182/blood.2021012805⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

مصطلحات موضوعية: Programmed cell death, Lymphoma, B-Cell, Carcinogenesis, DNA damage, Poly ADP ribose polymerase, Immunology, Poly (ADP-Ribose) Polymerase-1, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Biology, Biochemistry, Proinflammatory cytokine, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, B-cell lymphoma, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Proto-Oncogene Proteins c-myc / genetics, Oncogene, Poly (ADP-Ribose) Polymerase-1 / genetics, Cancer, Carcinogenesis / genetics, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, Cell Biology, Hematology, medicine.disease, 3. Good health, Lymphoma, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Neoplastic Lymphoma, 030220 oncology & carcinogenesis, Cancer research, B-Cell / genetics, Poly(ADP-ribose) Polymerases, Gene Deletion, Poly(ADP-ribose) Polymerases / genetics, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d97560700d6e5bc3cd5917c508aca61Test
https://hal.archives-ouvertes.fr/hal-03442516/documentTest

المؤلفون: Rodriguez-Martin, B., Alvarez, E.G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y.S., Temes, J., Garcia-Souto, D., Detering, H., Li, Y., Rodriguez-Castro, J., Dueso-Barroso, A., Bruzos, A.L., Dentro, S.C., Blanco, M.G., Contino, G., Ardeljan, D., Tojo, M., Roberts, N.D., Zumalave, S., Edwards, P.A., Weischenfeldt, J., Puiggròs, M., Chong, Z., Chen, K., Lee, E.A., Wala, J.A., Raine, K., Butler, A., Waszak, S.M., Navarro, F.C.P., Schumacher, S.E., Monlong, J., Maura, F., Bolli, N., Bourque, G., Gerstein, M., Park, P.J., Wedge, D.C., Beroukhim, R., Torrents, D., Korbel, J.O., Martincorena, I., Fitzgerald, R.C., Van Loo, P., Kazazian, H.H., Burns, K.H., Akdemir, K.C., Boutros, P.C., Bowtell, D.D.L., Brors, B., Campbell, P.J., Chan, K., Cortés-Ciriano, I., Dunford, A.J., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J.L., Frenkel-Morgenstern, M., Garsed, D.W., Gordenin, D.A., Haan, D., Haber, J.E., Hess, J.M., Hutter, B., Imielinski, M., Jones, D.T.W., Kazanov, M.D., Klimczak, L.J., Koh, Y., Kumar, K., Lee, J.J.-K., Lynch, A.G., Macintyre, G., Markowetz, F., Martinez-Fundichely, A., Meyerson, M., Miyano, S., Nakagawa, H., Ossowski, S., Pearson, J.V., Rippe, K., Roberts, S.A., Scully, R., Shackleton, M., Sidiropoulos, N., Sieverling, L., Stewart, C., Tubio, J.M.C., Villasante, I., Waddell, N., Yang, L., Yao, X., Yoon, S.-S., Zhang, C.-Z.

المساهمون: University of St Andrews. School of Medicine, University of St Andrews. Statistics, University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis, University of St Andrews. Cellular Medicine Division

المصدر: Nature Genetics
Nature Genetics, 52, 306-319
Rodriguez-Martin, B, Alvarez, E G, Baez-Ortega, A, Zamora, J, Supek, F, Demeulemeester, J, Santamarina, M, Ju, Y S, Temes, J, Garcia-Souto, D, Detering, H, Li, Y, Rodriguez-Castro, J, Dueso-Barroso, A, Bruzos, A L, Dentro, S C, Blanco, M G, Contino, G, Ardeljan, D, Tojo, M, Roberts, N D, Zumalave, S, Edwards, P A, Weischenfeldt, J, Puiggròs, M, Chong, Z, Chen, K, Lee, E A, Wala, J A, Raine, K, Butler, A, Waszak, S M, Navarro, F C P, Schumacher, S E, Monlong, J, Maura, F, Bolli, N, Bourque, G, Gerstein, M, Park, P J, Wedge, D C, Beroukhim, R, Torrents, D, Korbel, J O, Martincorena, I, Fitzgerald, R C, Van Loo, P, Kazazian, H H, Burns, K H, Akdemir, K C, Alvarez, E G, Baez-Ortega, A, Beroukhim, R, Boutros, P C, Bowtell, D D L, Brors, B, Burns, K H, Campbell, P J, Chan, K, Chen, K, Cortés-Ciriano, I, Dueso-Barroso, A, Dunford, A J, Edwards, P A, Estivill, X, Etemadmoghadam, D, Feuerbach, L, Fink, J L, Frenkel-Morgenstern, M, Garsed, D W, Gerstein, M, Gordenin, D A, Haan, D, Haber, J E, Hess, J M, Hutter, B, Imielinski, M, Jones, D T W, Ju, Y S, Kazanov, M D, Klimczak, L J, Koh, Y, Korbel, J O, Kumar, K, Lee, E A, Lee, JJ-K, Li, Y, Lynch, A G, Macintyre, G, Markowetz, F, Martincorena, I, Martinez-Fundichely, A, Meyerson, M, Miyano, S, Nakagawa, H, Navarro, F C P, Ossowski, S, Park, P J, Pearson, J V, Puiggròs, M, Rippe, K, Roberts, N D, Roberts, S A, Rodriguez-Martin, B, Schumacher, S E, Scully, R, Shackleton, M, Sidiropoulos, N, Sieverling, L, Stewart, C, Torrents, D, Tubio, J M C, Villasante, I, Waddell, N, Wala, J A, Weischenfeldt, J, Yang, L, Yao, X, Yoon, S-S, Zamora, J, Zhang, C-Z, Campbell, P J & Tubio, J M C 2020, ' Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition ', Nature Genetics, vol. 52, no. 3, pp. 306-319 . https://doi.org/10.1038/s41588-019-0562-0Test
Rodriguez-Martin, B, Alvarez, E G, Baez-Ortega, A, Zamora, J, Supek, F, Demeulemeester, J, Santamarina, M, Ju, Y S, Temes, J, Garcia-Souto, D, Detering, H, Li, Y, Rodriguez-Castro, J, Dueso-Barroso, A, Bruzos, A L, Dentro, S C, Blanco, M G, Contino, G, Ardeljan, D, Tojo, M, Roberts, N D, Zumalave, S, Edwards, P A W, Weischenfeldt, J, Puiggròs, M, Chong, Z, Chen, K, Lee, E A, Wala, J A, Raine, K, Butler, A, Waszak, S M, Navarro, F C P, Schumacher, S E, Monlong, J, Maura, F, Bolli, N, Bourque, G, Gerstein, M, Park, P J, Wedge, D C, Beroukhim, R, Torrents, D, Korbel, J O, Martincorena, I, Fitzgerald, R C, Van Loo, P, Kazazian, H H, Sidiropoulos, N, Weischenfeldt, J, PCAWG Structural Variation Working Group & PCAWG Consortium 2020, ' Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition ', Nature Genetics, vol. 52, no. 3, pp. 306-319 . https://doi.org/10.1038/s41588-019-0562-0Test
Nature Genetics, 52, 3, pp. 306-319

مصطلحات موضوعية: Somatic cell, Carcinogenesis, QH301 Biology, Retrotransposon, medicine.disease_cause, Genoma humà, Genome, 0302 clinical medicine, Neoplasms, ELEMENTS, Carcinogènesi, Cancer, Genetics, Gene Rearrangement, Genetics & Heredity, 0303 health sciences, Women's cancers Radboud Institute for Molecular Life Sciences [Radboudumc 17], Manchester Cancer Research Centre, 3rd-DAS, Genomics, Neoplasms/genetics, SOMATIC RETROTRANSPOSITION, Women's cancers Radboud Institute for Health Sciences [Radboudumc 17], 3. Good health, READ ALIGNMENT, 030220 oncology & carcinogenesis, Retroelements/genetics, Life Sciences & Biomedicine, Retroelements, INSTABILITY, L1 RETROTRANSPOSITION, QH426 Genetics, Biology, Article, Structural variation, RC0254, 03 medical and health sciences, QH301, SDG 3 - Good Health and Well-being, medicine, Humans, QH426, 030304 developmental biology, Tumors, Science & Technology, LANDSCAPE, RC0254 Neoplasms. Tumors. Oncology (including Cancer), Genome, Human, ResearchInstitutes_Networks_Beacons/mcrc, DELETION, Gene rearrangement, DNA, Gene Rearrangement/genetics, Long interspersed nuclear element, Reordenament genètic, Long Interspersed Nucleotide Elements, Long Interspersed Nucleotide Elements/genetics, Genome, Human/genetics, Carcinogenesis/genetics, Genètica

وصف الملف: Print-Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1bee2c01b8278d49bbe8813c2939cfTest
https://lirias.kuleuven.be/handle/123456789/651107Test

المؤلفون: Laetitia Wiggers, Benedikt B. Kaufer, Damien Coupeau, Benoît Muylkens, André Claude Mbouombouo Mfossa, Ahmed Kheimar, Srđan Pejaković

المصدر: Journal of Virology

مصطلحات موضوعية: Telomerase, 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche, Viral/genetics, Carcinogenesis, Marek Disease/virology, Virus Replication, medicine.disease_cause, Transformation and Oncogenesis, 0403 veterinary science, Transcription (biology), virus-induced oncogenesis, Site-Directed, Viral, Promoter Regions, Genetic, viral telomerase RNA subunit, 0303 health sciences, DNA methylation, 04 agricultural and veterinary sciences, Methylation, Gallid herpesvirus type 2, Cell biology, c-Myc, CpG site, RNA, Viral, Gene Expression Regulation, Viral, DNA Methylation/physiology, 040301 veterinary sciences, Immunology, E-box, Biology, Microbiology, epigenetic regulation, Cell Line, Promoter Regions, 03 medical and health sciences, Genetic, Virology, Marek Disease, medicine, Animals, Epigenetics, Herpesvirus 2, Gallid, 030304 developmental biology, Herpesvirus 2, telomerase activity, Telomerase/genetics, Gene Expression Regulation, Gallid/enzymology, Viral replication, Mutagenesis, Insect Science, Mutation, Mutagenesis, Site-Directed, RNA, Carcinogenesis/genetics, Chickens

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddc01e8f06ff9234db8f471a37b4ad0Test
https://refubium.fu-berlin.de/handle/fub188/29591Test

المؤلفون: Aurélien Perrin, Helene Trauchessec, Orsolya Leidecker, Aymeric P. Bailly, Chantal Maghames, Anton Gartner, Marina Serrano-Macia, Dimitris P. Xirodimas, María L. Martínez-Chantar

المساهمون: BioSciences Lyon-Gerland (BLG), École normale supérieure de Lyon (ENS de Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Biologie cellulaire de Montpellier (CRBM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd), Liver Unit, Clínica Universitaria, CIBER-EHD, Wellcome Trust Biocentre MSI/WTB Complex, University of Dundee, Welcome Trust Centre for Gene Regulation and Expression, École normale supérieure - Lyon (ENS Lyon)-Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Centre de recherche en Biologie Cellulaire (CRBM), Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1), Centre de recherches de biochimie macromoléculaire (CRBM), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-IFR122-Centre National de la Recherche Scientifique (CNRS)

المصدر: Cell Reports
Cell Reports, 2019, 29 (1), pp.212-224.e8. ⟨10.1016/j.celrep.2019.08.070⟩
Cell Reports, Elsevier Inc, 2019, 29 (1), pp.212-224.e8. ⟨10.1016/j.celrep.2019.08.070⟩
Cell Reports, Vol 29, Iss 1, Pp 212-224.e8 (2019)

مصطلحات موضوعية: 0301 basic medicine, Carcinogenesis, [SDV]Life Sciences [q-bio], NEDP1/SENP8, NEDD8, Mice, 0302 clinical medicine, Ubiquitin, MESH: Adenosine Triphosphatases / genetics* Amino Acid Sequence Animals Carcinogenesis / genetics Cell Line, Tumor DNA Damage / genetics* Endopeptidases / genetics* Female HSP70 Heat-Shock Proteins / genetics* Humans Lysine / genetics MCF-7 Cells Mice NEDD8 Protein / genetics* Ubiquitin / genetics, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, HSP70, chemistry.chemical_classification, Adenosine Triphosphatases, biology, Chemistry, apoptosis, hepatocellular carcinoma, 3. Good health, Cell biology, MCF-7 Cells, C. elegans, Female, NEDD8 Protein, DNA damage, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, proteomics, APAF1, Cell Line, Tumor, Endopeptidases, Animals, Humans, K11/K48 chains, HSP70 Heat-Shock Proteins, Amino Acid Sequence, Lysine, Hsp70, 030104 developmental biology, Enzyme, lcsh:Biology (General), Apoptosis, Chaperone (protein), biology.protein, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d39ecc1dfd219f6cb99ac162e2d477Test
https://hal.umontpellier.fr/hal-02339558Test

المؤلفون: Bernt Popp, Abbas Agaimy, Georgia Vasileiou, Marjolijn C.J. Jongmans, Illja J. Diets, Nel Roeleveld, Nicoline Hoogerbrugge, Markus Metzler, Denisa Ilencikova, Roland P. Kuiper, Annelies M. C. Mavinkurve-Groothuis, Didem Seven, Steffen Uebe, Arif B. Ekici, Jenny Wegert, Rajith Bhaskaran, Esmé Waanders, Manfred Gessler, Christian Thiel, Juliane Hoyer, Ronald R. de Krijger, André Reis, Norbert Graf, Simon V. van Reijmersdal, Christian Vokuhl, Michel V. Hadjihannas

المساهمون: İÜC

المصدر: International Journal of Cancer, 145, 4, pp. 941-951
International Journal of Cancer, 145, 941-951
International Journal of Cancer, 145(4), 941. Wiley-Liss Inc.

مصطلحات موضوعية: Male, Haploinsufficiency/genetics, Cancer Research, Carcinogenesis, Whole Exome Sequencing/methods, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Loss of Heterozygosity, Haploinsufficiency, Tripartite Motif-Containing Protein 28, medicine.disease_cause, Germ-Line Mutation/genetics, Kidney Neoplasms/genetics, Germline, Loss of Function Mutation/genetics, 0302 clinical medicine, Loss of Function Mutation, Tumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14], Child, Non-U.S. Gov't, Exome sequencing, Genetic Predisposition to Disease/genetics, Research Support, Non-U.S. Gov't, Wilms tumor, Wilms Tumor/physiology, DNA, Neoplasm, Kidney Neoplasms, Oncology, Child, Preschool, 030220 oncology & carcinogenesis, Female, Heterozygote, Genes, Wilms Tumor, Mitotic crossover, Genotype, Tumor suppressor gene, DNA repair, Biology, Research Support, Wilms Tumor, 03 medical and health sciences, Exome Sequencing, Journal Article, medicine, Humans, Genetic Predisposition to Disease, Preschool, DNA, Neoplasm/genetics, Germ-Line Mutation, Genes, Wilms Tumor/physiology, Neoplasm/genetics, Loss of Heterozygosity/genetics, TRIM28, Infant, Wilms' tumor, DNA, medicine.disease, haploinsufficiency, Wilms Tumor/genetics, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Genes, Tripartite Motif-Containing Protein 28/genetics, Cancer research, Carcinogenesis/genetics, genetic predisposition

وصف الملف: application/pdf; image/pdf; text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7b87a0f678c336c2af58b01b299313Test
https://doi.org/10.1002/ijc.32167Test

المؤلفون: Ayse Gaye Tomatir, Hakan Akca, Pervin Elvan Tokgun, Serap Kurt, Onur Tokgun

مصطلحات موضوعية: 0301 basic medicine, miRNA gene, Carcinogenesis, complementary DNA, MCF-7 cell line, 0302 clinical medicine, lncRNA gene, oncogene, genetics, gene knockdown, Regulation of gene expression, MEG3, Gene knockdown, quantitative analysis, breast tumor, HOTAIR, General Medicine, gene expression regulation, Cell cycle, protein function, RNA analysis, Long non-coding RNA, unclassified drug, Breast Neoplasms/*genetics/pathology, Carcinogenesis/genetics, Cell Line, Tumor, Cell Proliferation/genetics, Female, Gene Expression Regulation, Neoplastic, Humans, MCF-7 Cells, Oncogenes, Proto-Oncogene Proteins c-myc/biosynthesis/*genetics, RNA, Long Noncoding/*genetics, female, priority journal, real time polymerase chain reaction, 030220 oncology & carcinogenesis, protein GAS5, RNA, Long Noncoding, lentivirus vector, Long noncoding RNA HOTAIR, protein RNA binding, cell cycle regulation, signal transduction, gene overexpression, long untranslated RNA, Breast Neoplasms, Biology, RNA gene, Article, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, Breast cancer, breast cancer, breast cancer cell line, Genetics, medicine, Long intervening noncoding RNA p21 protein, controlled study, human, tumor suppressor protein, Cell Proliferation, tumor cell line, medicine.disease, 030104 developmental biology, Myc protein, Cancer research, protein MEG3, pathology, GAS5, biosynthesis, untranslated RNA, MYC protein, human

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9589910e50c221628b0d2b6d38b42af9Test

المؤلفون: Alfred L. Garfall, Alison K. Spencer, Vasilena Gocheva, Marsha L. Quick, Jemila C. Kester, Robert L. Bowman, Leila Akkari, Johanna A. Joyce

المصدر: Genes and Development, vol. 30, no. 2, pp. 220-232

مصطلحات موضوعية: 0301 basic medicine, Proteases, Carcinogenesis, Angiogenesis, medicine.medical_treatment, Apoptosis, Biology, medicine.disease_cause, Cathepsin B, Gene Knockout Techniques, Mice, 03 medical and health sciences, Genetics, medicine, Animals, Neoplasm Invasiveness, Cathepsin, Tumor microenvironment, Protease, Neovascularization, Pathologic, Macrophages, Cancer, medicine.disease, Cathepsins, Apoptosis/genetics, Carcinogenesis/genetics, Carcinoma, Neuroendocrine/enzymology, Carcinoma, Neuroendocrine/genetics, Cathepsins/genetics, Cathepsins/metabolism, Disease Models, Animal, Gene Deletion, Gene Expression Regulation, Neoplastic, Macrophages/enzymology, Mice, Inbred C57BL, Neoplasm Invasiveness/genetics, Neovascularization, Pathologic/enzymology, Neovascularization, Pathologic/genetics, Pancreatic Neoplasms/enzymology, Pancreatic Neoplasms/genetics, Carcinoma, Neuroendocrine, Pancreatic Neoplasms, 030104 developmental biology, Cancer research, Research Paper, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f810c9c89de5e9fcdba280b4411e1958Test
https://doi.org/10.1101/gad.270439.115Test

المؤلفون: Rishabh Chawla, Lisa Hoenicke, Nir Rozenblum, Jule Harbig, Johannes Zuber, Marco Seehawer, Gregory J. Dore, Hien Dang, Pierre-François Roux, Florian Heinzmann, Mihael Vucur, Thomas Longerich, Tom Luedde, Bence Sipos, Oliver Bischof, Tae-Won Kang, Xin Wei Wang, Lucas Robinson, Mathias Heikenwalder, Sabrina Klotz, Mareike Roth, Thorsten Buch, Luana D’Artista, Lars Zender

المساهمون: Universitätsklinikum Tübingen - University Hospital of Tübingen, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe labellisée Ligue contre le Cancer, National Cancer Institute [Bethesda] (NCI-NIH), National Institutes of Health [Bethesda] (NIH), Universität Zürich [Zürich] = University of Zurich (UZH), Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), RWTH Aachen University, Vienna Biocenter - VBC [Austria], University of Tübingen, Heidelberg University Hospital [Heidelberg], German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), German Cancer Consortium [Heidelberg] (DKTK), This work was supported by the ERC Consolidator Grant ‘CholangioConcept’ (to L.Z.), the German Research Foundation (DFG): grants FOR2314, SFB685, SFB/TR209 and the Gottfried Wilhelm Leibniz Program (to L.Z.). Further funding was provided by the German Ministry for Education and Research (BMBF) (e:Med/Multiscale HCC), the German Universities Excellence Initiative (third funding line: ‘future concept’), the German Center for Translational Cancer Research (DKTK), the German-Israeli Cooperation in Cancer Research (DKFZ-MOST) (to L.Z.) and the Intramural Research Program of the Centre for Cancer Research, National Cancer Institute, National Institutes of Health (to X.W.W.). The group of O.B. is supported by grants from ANR-BMFT, Fondation ARC pour la recherche sur le Cancer, INSERM, and the National Cancer Institute of the National Institutes of Health under Award Number R01CA136533. O.B. is a CNRS fellow., We thank E. Rist, P. Schiemann, C. Fellmeth, C.-J. Hsieh, D. Heide and J. Hetzer for technical help or assistance. We thank A. Weber for providing TLR2 and TLR4 knockout mice and W. S. Alexander and The Walter and Eliza Hall Institute of Medical Research for providing Mlklfl/fl mice. The Cas9n–p19Arf sgRNA vector was provided by W. Xue. We thank the c.ATG facility of Tuebingen University and CeGaT Tuebingen for exome sequencing and data analysis., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), University of Zurich, Zender, Lars

المصدر: Nature
Nature, Nature Publishing Group, 2018, 562 (7725), pp.69-75. ⟨10.1038/s41586-018-0519-y⟩
Nature, 2018, 562 (7725), pp.69-75. ⟨10.1038/s41586-018-0519-y⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Necrosis*/genetics, Cellular differentiation, MESH: Cell Lineage*/genetics, MESH: Carcinoma, Hepatocellular/pathology, MESH: Tumor Microenvironment, 10239 Institute of Laboratory Animal Science, MESH: Animals, Cancer epigenetics, MESH: Apoptosis*/genetics, MESH: Transcription Factors/metabolism, MESH: Proto-Oncogene Proteins c-akt/genetics, Multidisciplinary, MESH: Carcinoma, Hepatocellular/genetics, MESH: Cyclin-Dependent Kinase Inhibitor p16/deficiency, 3. Good health, MESH: Carcinogenesis/genetics, MESH: Cholangiocarcinoma/genetics, MESH: Mosaicism, MESH: T-Box Domain Proteins/genetics, Liver cancer, Cancer microenvironment, MESH: Cell Differentiation, Necroptosis, MESH: Cholangiocarcinoma/pathology, MESH: Liver Neoplasms/pathology, Context (language use), 610 Medicine & health, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, MESH: DNA-Binding Proteins/metabolism, Article, 03 medical and health sciences, MESH: DNA Transposable Elements/genetics, MESH: Gene Expression Profiling, MESH: Hepatocytes/metabolism, medicine, MESH: Transcription Factors/genetics, MESH: Mice, MESH: Genes, myc, MESH: Liver Neoplasms/genetics, Tumor microenvironment, 1000 Multidisciplinary, MESH: DNA-Binding Proteins/genetics, MESH: Humans, Epigenome, medicine.disease, MESH: Male, digestive system diseases, MESH: Genes, ras, 030104 developmental biology, MESH: Hepatocytes/pathology, Cancer research, Hepatic stellate cell, 570 Life sciences, biology, MESH: Epigenesis, Genetic/genetics, MESH: Cytokines/metabolism, MESH: Disease Models, Animal, MESH: Female, MESH: T-Box Domain Proteins/metabolism

وصف الملف: Seehawer_2018_NATURE_Necroptosis_liver.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02caf225f5c633bfb7fa5ddb2d717963Test

المؤلفون: Li Ding, Matthew H. Bailey, Eduard Porta-Pardo, Vesteinn Thorsson, Antonio Colaprico, Denis Bertrand, David L. Gibbs, Amila Weerasinghe, Kuan-lin Huang, Collin Tokheim, Isidro Cortés-Ciriano, Reyka Jayasinghe, Feng Chen, Lihua Yu, Sam Sun, Catharina Olsen, Jaegil Kim, Alison M. Taylor, Andrew D. Cherniack, Rehan Akbani, Chayaporn Suphavilai, Niranjan Nagarajan, Joshua M. Stuart, Gordon B. Mills, Matthew A. Wyczalkowski, Benjamin G. Vincent, Carolyn M. Hutter, Jean Claude Zenklusen, Katherine A. Hoadley, Michael C. Wendl, llya Shmulevich, Alexander J. Lazar, David A. Wheeler, Gad Getz, Samantha J. Caesar-Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Heidi J. Sofia, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Jiashan (Julia) Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy DeFreitas, Scott Frazer, Nils Gehlenborg, David I. Heiman, Michael S. Lawrence, Pei Lin, Sam Meier, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila Reynolds, Ilya Shmulevich, Wei Zhang, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi, Anil Korkut, Jun Li, Han Liang, Shiyun Ling, Wenbin Liu, Yiling Lu, Kwok-Shing Ng, Arvind Rao, Michael Ryan, Jing Wang, John N. Weinstein, Jiexin Zhang, Adam Abeshouse, Joshua Armenia, Debyani Chakravarty, Walid K. Chatila, Ino de Bruijn, Jianjiong Gao, Benjamin E. Gross, Zachary J. Heins, Ritika Kundra, Konnor La, Marc Ladanyi, Augustin Luna, Moriah G. Nissan, Angelica Ochoa, Sarah M. Phillips, Ed Reznik, Francisco Sanchez-Vega, Chris Sander, Nikolaus Schultz, Robert Sheridan, S. Onur Sumer, Yichao Sun, Barry S. Taylor, Jioajiao Wang, Hongxin Zhang, Pavana Anur, Myron Peto, Paul Spellman, Christopher Benz, Christopher K. Wong, Christina Yau, D. Neil Hayes, Joel S. Parker, Matthew D. Wilkerson, Adrian Ally, Miruna Balasundaram, Reanne Bowlby, Denise Brooks, Rebecca Carlsen, Eric Chuah, Noreen Dhalla, Robert Holt, Steven J.M. Jones, Katayoon Kasaian, Darlene Lee, Yussanne Ma, Marco A. Marra, Michael Mayo, Richard A. Moore, Andrew J. Mungall, Karen Mungall, A. Gordon Robertson, Sara Sadeghi, Jacqueline E. Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Kane Tse, Tina Wong, Ashton C. Berger, Rameen Beroukhim, Carrie Cibulskis, Stacey B. Gabriel, Galen F. Gao, Gavin Ha, Matthew Meyerson, Steven E. Schumacher, Juliann Shih, Melanie H. Kucherlapati, Raju S. Kucherlapati, Stephen Baylin, Leslie Cope, Ludmila Danilova, Moiz S. Bootwalla, Phillip H. Lai, Dennis T. Maglinte, David J. Van Den Berg, Daniel J. Weisenberger, J. Todd Auman, Saianand Balu, Tom Bodenheimer, Cheng Fan, Alan P. Hoyle, Stuart R. Jefferys, Corbin D. Jones, Shaowu Meng, Piotr A. Mieczkowski, Lisle E. Mose, Amy H. Perou, Charles M. Perou, Jeffrey Roach, Yan Shi, Janae V. Simons, Tara Skelly, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, Huihui Fan, Toshinori Hinoue, Peter W. Laird, Hui Shen, Wanding Zhou, Michelle Bellair, Kyle Chang, Kyle Covington, Chad J. Creighton, Huyen Dinh, HarshaVardhan Doddapaneni, Lawrence A. Donehower, Jennifer Drummond, Richard A. Gibbs, Robert Glenn, Walker Hale, Yi Han, Jianhong Hu, Viktoriya Korchina, Sandra Lee, Lora Lewis, Wei Li, Xiuping Liu, Margaret Morgan, Donna Morton, Donna Muzny, Jireh Santibanez, Margi Sheth, Eve Shinbrot, Linghua Wang, Min Wang, Liu Xi, Fengmei Zhao, Julian Hess, Elizabeth L. Appelbaum, Matthew Bailey, Matthew G. Cordes, Catrina C. Fronick, Lucinda A. Fulton, Robert S. Fulton, Cyriac Kandoth, Elaine R. Mardis, Michael D. McLellan, Christopher A. Miller, Heather K. Schmidt, Richard K. Wilson, Daniel Crain, Erin Curley, Johanna Gardner, Kevin Lau, David Mallery, Scott Morris, Joseph Paulauskis, Robert Penny, Candace Shelton, Troy Shelton, Mark Sherman, Eric Thompson, Peggy Yena, Jay Bowen, Julie M. Gastier-Foster, Mark Gerken, Kristen M. Leraas, Tara M. Lichtenberg, Nilsa C. Ramirez, Lisa Wise, Erik Zmuda, Niall Corcoran, Tony Costello, Christopher Hovens, Andre L. Carvalho, Ana C. de Carvalho, José H. Fregnani, Adhemar Longatto-Filho, Rui M. Reis, Cristovam Scapulatempo-Neto, Henrique C.S. Silveira, Daniel O. Vidal, Andrew Burnette, Jennifer Eschbacher, Beth Hermes, Ardene Noss, Rosy Singh, Matthew L. Anderson, Patricia D. Castro, Michael Ittmann, David Huntsman, Bernard Kohl, Xuan Le, Richard Thorp, Chris Andry, Elizabeth R. Duffy, Vladimir Lyadov, Oxana Paklina, Galiya Setdikova, Alexey Shabunin, Mikhail Tavobilov, Christopher McPherson, Ronald Warnick, Ross Berkowitz, Daniel Cramer, Colleen Feltmate, Neil Horowitz, Adam Kibel, Michael Muto, Chandrajit P. Raut, Andrei Malykh, Jill S. Barnholtz-Sloan, Wendi Barrett, Karen Devine, Jordonna Fulop, Quinn T. Ostrom, Kristen Shimmel, Yingli Wolinsky, Andrew E. Sloan, Agostino De Rose, Felice Giuliante, Marc Goodman, Beth Y. Karlan, Curt H. Hagedorn, John Eckman, Jodi Harr, Jerome Myers, Kelinda Tucker, Leigh Anne Zach, Brenda Deyarmin, Hai Hu, Leonid Kvecher, Caroline Larson, Richard J. Mural, Stella Somiari, Ales Vicha, Tomas Zelinka, Joseph Bennett, Mary Iacocca, Brenda Rabeno, Patricia Swanson, Mathieu Latour, Louis Lacombe, Bernard Têtu, Alain Bergeron, Mary McGraw, Susan M. Staugaitis, John Chabot, Hanina Hibshoosh, Antonia Sepulveda, Tao Su, Timothy Wang, Olga Potapova, Olga Voronina, Laurence Desjardins, Odette Mariani, Sergio Roman-Roman, Xavier Sastre, Marc-Henri Stern, Feixiong Cheng, Sabina Signoretti, Andrew Berchuck, Darell Bigner, Eric Lipp, Jeffrey Marks, Shannon McCall, Roger McLendon, Angeles Secord, Alexis Sharp, Madhusmita Behera, Daniel J. Brat, Amy Chen, Keith Delman, Seth Force, Fadlo Khuri, Kelly Magliocca, Shishir Maithel, Jeffrey J. Olson, Taofeek Owonikoko, Alan Pickens, Suresh Ramalingam, Dong M. Shin, Gabriel Sica, Erwin G. Van Meir, Hongzheng Zhang, Wil Eijckenboom, Ad Gillis, Esther Korpershoek, Leendert Looijenga, Wolter Oosterhuis, Hans Stoop, Kim E. van Kessel, Ellen C. Zwarthoff, Chiara Calatozzolo, Lucia Cuppini, Stefania Cuzzubbo, Francesco DiMeco, Gaetano Finocchiaro, Luca Mattei, Alessandro Perin, Bianca Pollo, Chu Chen, John Houck, Pawadee Lohavanichbutr, Arndt Hartmann, Christine Stoehr, Robert Stoehr, Helge Taubert, Sven Wach, Bernd Wullich, Witold Kycler, Dawid Murawa, Maciej Wiznerowicz, Ki Chung, W. Jeffrey Edenfield, Julie Martin, Eric Baudin, Glenn Bubley, Raphael Bueno, Assunta De Rienzo, William G. Richards, Steven Kalkanis, Tom Mikkelsen, Houtan Noushmehr, Lisa Scarpace, Nicolas Girard, Marta Aymerich, Elias Campo, Eva Giné, Armando López Guillermo, Nguyen Van Bang, Phan Thi Hanh, Bui Duc Phu, Yufang Tang, Howard Colman, Kimberley Evason, Peter R. Dottino, John A. Martignetti, Hani Gabra, Hartmut Juhl, Teniola Akeredolu, Serghei Stepa, Dave Hoon, Keunsoo Ahn, Koo Jeong Kang, Felix Beuschlein, Anne Breggia, Michael Birrer, Debra Bell, Mitesh Borad, Alan H. Bryce, Erik Castle, Vishal Chandan, John Cheville, John A. Copland, Michael Farnell, Thomas Flotte, Nasra Giama, Thai Ho, Michael Kendrick, Jean-Pierre Kocher, Karla Kopp, Catherine Moser, David Nagorney, Daniel O’Brien, Brian Patrick O’Neill, Tushar Patel, Gloria Petersen, Florencia Que, Michael Rivera, Lewis Roberts, Robert Smallridge, Thomas Smyrk, Melissa Stanton, R. Houston Thompson, Michael Torbenson, Ju Dong Yang, Lizhi Zhang, Fadi Brimo, Jaffer A. Ajani, Ana Maria Angulo Gonzalez, Carmen Behrens, Jolanta Bondaruk, Russell Broaddus, Bogdan Czerniak, Bita Esmaeli, Junya Fujimoto, Jeffrey Gershenwald, Charles Guo, Christopher Logothetis, Funda Meric-Bernstam, Cesar Moran, Lois Ramondetta, David Rice, Anil Sood, Pheroze Tamboli, Timothy Thompson, Patricia Troncoso, Anne Tsao, Ignacio Wistuba, Candace Carter, Lauren Haydu, Peter Hersey, Valerie Jakrot, Hojabr Kakavand, Richard Kefford, Kenneth Lee, Georgina Long, Graham Mann, Michael Quinn, Robyn Saw, Richard Scolyer, Kerwin Shannon, Andrew Spillane, Jonathan Stretch, Maria Synott, John Thompson, James Wilmott, Hikmat Al-Ahmadie, Timothy A. Chan, Ronald Ghossein, Anuradha Gopalan, Douglas A. Levine, Victor Reuter, Samuel Singer, Bhuvanesh Singh, Nguyen Viet Tien, Thomas Broudy, Cyrus Mirsaidi, Praveen Nair, Paul Drwiega, Judy Miller, Jennifer Smith, Howard Zaren, Joong-Won Park, Nguyen Phi Hung, Electron Kebebew, W. Marston Linehan, Adam R. Metwalli, Karel Pacak, Peter A. Pinto, Mark Schiffman, Laura S. Schmidt, Cathy D. Vocke, Nicolas Wentzensen, Robert Worrell, Hannah Yang, Marc Moncrieff, Chandra Goparaju, Jonathan Melamed, Harvey Pass, Natalia Botnariuc, Irina Caraman, Mircea Cernat, Inga Chemencedji, Adrian Clipca, Serghei Doruc, Ghenadie Gorincioi, Sergiu Mura, Maria Pirtac, Irina Stancul, Diana Tcaciuc, Monique Albert, Iakovina Alexopoulou, Angel Arnaout, John Bartlett, Jay Engel, Sebastien Gilbert, Jeremy Parfitt, Harman Sekhon, George Thomas, Doris M. Rassl, Robert C. Rintoul, Carlo Bifulco, Raina Tamakawa, Walter Urba, Nicholas Hayward, Henri Timmers, Anna Antenucci, Francesco Facciolo, Gianluca Grazi, Mirella Marino, Roberta Merola, Ronald de Krijger, Anne-Paule Gimenez-Roqueplo, Alain Piché, Simone Chevalier, Ginette McKercher, Kivanc Birsoy, Gene Barnett, Cathy Brewer, Carol Farver, Theresa Naska, Nathan A. Pennell, Daniel Raymond, Cathy Schilero, Kathy Smolenski, Felicia Williams, Carl Morrison, Jeffrey A. Borgia, Michael J. Liptay, Mark Pool, Christopher W. Seder, Kerstin Junker, Larsson Omberg, Mikhail Dinkin, George Manikhas, Domenico Alvaro, Maria Consiglia Bragazzi, Vincenzo Cardinale, Guido Carpino, Eugenio Gaudio, David Chesla, Sandra Cottingham, Michael Dubina, Fedor Moiseenko, Renumathy Dhanasekaran, Karl-Friedrich Becker, Klaus-Peter Janssen, Julia Slotta-Huspenina, Mohamed H. Abdel-Rahman, Dina Aziz, Sue Bell, Colleen M. Cebulla, Amy Davis, Rebecca Duell, J. Bradley Elder, Joe Hilty, Bahavna Kumar, James Lang, Norman L. Lehman, Randy Mandt, Phuong Nguyen, Robert Pilarski, Karan Rai, Lynn Schoenfield, Kelly Senecal, Paul Wakely, Paul Hansen, Ronald Lechan, James Powers, Arthur Tischler, William E. Grizzle, Katherine C. Sexton, Alison Kastl, Joel Henderson, Sima Porten, Jens Waldmann, Martin Fassnacht, Sylvia L. Asa, Dirk Schadendorf, Marta Couce, Markus Graefen, Hartwig Huland, Guido Sauter, Thorsten Schlomm, Ronald Simon, Pierre Tennstedt, Oluwole Olabode, Mark Nelson, Oliver Bathe, Peter R. Carroll, June M. Chan, Philip Disaia, Pat Glenn, Robin K. Kelley, Charles N. Landen, Joanna Phillips, Michael Prados, Jeffry Simko, Karen Smith-McCune, Scott VandenBerg, Kevin Roggin, Ashley Fehrenbach, Ady Kendler, Suzanne Sifri, Ruth Steele, Antonio Jimeno, Francis Carey, Ian Forgie, Massimo Mannelli, Michael Carney, Brenda Hernandez, Benito Campos, Christel Herold-Mende, Christin Jungk, Andreas Unterberg, Andreas von Deimling, Aaron Bossler, Joseph Galbraith, Laura Jacobus, Michael Knudson, Tina Knutson, Deqin Ma, Mohammed Milhem, Rita Sigmund, Andrew K. Godwin, Rashna Madan, Howard G. Rosenthal, Clement Adebamowo, Sally N. Adebamowo, Alex Boussioutas, David Beer, Thomas Giordano, Anne-Marie Mes-Masson, Fred Saad, Therese Bocklage, Lisa Landrum, Robert Mannel, Kathleen Moore, Katherine Moxley, Russel Postier, Joan Walker, Rosemary Zuna, Michael Feldman, Federico Valdivieso, Rajiv Dhir, James Luketich, Edna M. Mora Pinero, Mario Quintero-Aguilo, Carlos Gilberto Carlotti, Jose Sebastião Dos Santos, Rafael Kemp, Ajith Sankarankuty, Daniela Tirapelli, James Catto, Kathy Agnew, Elizabeth Swisher, Jenette Creaney, Bruce Robinson, Carl Simon Shelley, Eryn M. Godwin, Sara Kendall, Cassaundra Shipman, Carol Bradford, Thomas Carey, Andrea Haddad, Jeffey Moyer, Lisa Peterson, Mark Prince, Laura Rozek, Gregory Wolf, Rayleen Bowman, Kwun M. Fong, Ian Yang, Robert Korst, W. Kimryn Rathmell, J. Leigh Fantacone-Campbell, Jeffrey A. Hooke, Albert J. Kovatich, Craig D. Shriver, John DiPersio, Bettina Drake, Ramaswamy Govindan, Sharon Heath, Timothy Ley, Brian Van Tine, Peter Westervelt, Mark A. Rubin, Jung Il Lee, Natália D. Aredes, Armaz Mariamidze

المساهمون: Ding L., Bailey M.H., Porta-Pardo E., Thorsson V., Colaprico A., Bertrand D., Gibbs D.L., Weerasinghe A., Huang K.-L., Tokheim C., Cortes-Ciriano I., Jayasinghe R., Chen F., Yu L., Sun S., Olsen C., Kim J., Taylor A.M., Cherniack A.D., Akbani R., Suphavilai C., Nagarajan N., Stuart J.M., Mills G.B., Wyczalkowski M.A., Vincent B.G., Hutter C.M., Zenklusen J.C., Hoadley K.A., Wendl M.C., Shmulevich L., Lazar A.J., Wheeler D.A., Getz G., Caesar-Johnson S.J., Demchok J.A., Felau I., Kasapi M., Ferguson M.L., Sofia H.J., Tarnuzzer R., Wang Z., Yang L., Zhang J.J., Chudamani S., Liu J., Lolla L., Naresh R., Pihl T., Sun Q., Wan Y., Wu Y., Cho J., DeFreitas T., Frazer S., Gehlenborg N., Heiman D.I., Lawrence M.S., Lin P., Meier S., Noble M.S., Saksena G., Voet D., Zhang H., Bernard B., Chambwe N., Dhankani V., Knijnenburg T., Kramer R., Leinonen K., Liu Y., Miller M., Reynolds S., Shmulevich I., Zhang W., Broom B.M., Hegde A.M., Ju Z., Kanchi R.S., Korkut A., Li J., Liang H., Ling S., Liu W., Lu Y., Ng K.-S., Rao A., Ryan M., Wang J., Weinstein J.N., Zhang J., Abeshouse A., Armenia J., Chakravarty D., Chatila W.K., de Bruijn I., Gao J., Gross B.E., Heins Z.J., Kundra R., La K., Ladanyi M., Luna A., Nissan M.G., Ochoa A., Phillips S.M., Reznik E., Sanchez-Vega F., Sander C., Schultz N., Sheridan R., Sumer S.O., Sun Y., Taylor B.S., Anur P., Peto M., Spellman P., Benz C., Wong C.K., Yau C., Hayes D.N., Parker J.S., Wilkerson M.D., Ally A., Balasundaram M., Bowlby R., Brooks D., Carlsen R., Chuah E., Dhalla N., Holt R., Jones S.J.M., Kasaian K., Lee D., Ma Y., Marra M.A., Mayo M., Moore R.A., Mungall A.J., Mungall K., Robertson A.G., Sadeghi S., Schein J.E., Sipahimalani P., Tam A., Thiessen N., Tse K., Wong T., Berger A.C., Beroukhim R., Cibulskis C., Gabriel S.B., Gao G.F., Ha G., Meyerson M., Schumacher S.E., Shih J., Kucherlapati M.H., Kucherlapati R.S., Baylin S., Cope L., Danilova L., Bootwalla M.S., Lai P.H., Maglinte D.T., Van Den Berg D.J., Weisenberger D.J., Auman J.T., Balu S., Bodenheimer T., Fan C., Hoyle A.P., Jefferys S.R., Jones C.D., Meng S., Mieczkowski P.A., Mose L.E., Perou A.H., Perou C.M., Roach J., Shi Y., Simons J.V., Skelly T., Soloway M.G., Tan D., Veluvolu U., Fan H., Hinoue T., Laird P.W., Shen H., Zhou W., Bellair M., Chang K., Covington K., Creighton C.J., Dinh H., Doddapaneni H., Donehower L.A., Drummond J., Gibbs R.A., Glenn R., Hale W., Han Y., Hu J., Korchina V., Lee S., Lewis L., Li W., Liu X., Morgan M., Morton D., Muzny D., Santibanez J., Sheth M., Shinbrot E., Wang L., Wang M., Xi L., Zhao F., Hess J., Appelbaum E.L., Bailey M., Cordes M.G., Fronick C.C., Fulton L.A., Fulton R.S., Kandoth C., Mardis E.R., McLellan M.D., Miller C.A., Schmidt H.K., Wilson R.K., Crain D., Curley E., Gardner J., Lau K., Mallery D., Morris S., Paulauskis J., Penny R., Shelton C., Shelton T., Sherman M., Thompson E., Yena P., Bowen J., Gastier-Foster J.M., Gerken M., Leraas K.M., Lichtenberg T.M., Ramirez N.C., Wise L., Zmuda E., Corcoran N., Costello T., Hovens C., Carvalho A.L., de Carvalho A.C., Fregnani J.H., Longatto-Filho A., Reis R.M., Scapulatempo-Neto C., Silveira H.C.S., Vidal D.O., Burnette A., Eschbacher J., Hermes B., Noss A., Singh R., Anderson M.L., Castro P.D., Ittmann M., Huntsman D., Kohl B., Le X., Thorp R., Andry C., Duffy E.R., Lyadov V., Paklina O., Setdikova G., Shabunin A., Tavobilov M., McPherson C., Warnick R., Berkowitz R., Cramer D., Feltmate C., Horowitz N., Kibel A., Muto M., Raut C.P., Malykh A., Barnholtz-Sloan J.S., Barrett W., Devine K., Fulop J., Ostrom Q.T., Shimmel K., Wolinsky Y., Sloan A.E., De Rose A., Giuliante F., Goodman M., Karlan B.Y., Hagedorn C.H., Eckman J., Harr J., Myers J., Tucker K., Zach L.A., Deyarmin B., Hu H., Kvecher L., Larson C., Mural R.J., Somiari S., Vicha A., Zelinka T., Bennett J., Iacocca M., Rabeno B., Swanson P., Latour M., Lacombe L., Tetu B., Bergeron A., McGraw M., Staugaitis S.M., Chabot J., Hibshoosh H., Sepulveda A., Su T., Wang T., Potapova O., Voronina O., Desjardins L., Mariani O., Roman-Roman S., Sastre X., Stern M.-H., Cheng F., Signoretti S., Berchuck A., Bigner D., Lipp E., Marks J., McCall S., McLendon R., Secord A., Sharp A., Behera M., Brat D.J., Chen A., Delman K., Force S., Khuri F., Magliocca K., Maithel S., Olson J.J., Owonikoko T., Pickens A., Ramalingam S., Shin D.M., Sica G., Van Meir E.G., Eijckenboom W., Gillis A., Korpershoek E., Looijenga L., Oosterhuis W., Stoop H., van Kessel K.E., Zwarthoff E.C., Calatozzolo C., Cuppini L., Cuzzubbo S., DiMeco F., Finocchiaro G., Mattei L., Perin A., Pollo B., Chen C., Houck J., Lohavanichbutr P., Hartmann A., Stoehr C., Stoehr R., Taubert H., Wach S., Wullich B., Kycler W., Murawa D., Wiznerowicz M., Chung K., Edenfield W.J., Martin J., Baudin E., Bubley G., Bueno R., De Rienzo A., Richards W.G., Kalkanis S., Mikkelsen T., Noushmehr H., Scarpace L., Girard N., Aymerich M., Campo E., Gine E., Guillermo A.L., Van Bang N., Hanh P.T., Phu B.D., Tang Y., Colman H., Evason K., Dottino P.R., Martignetti J.A., Gabra H., Juhl H., Akeredolu T., Stepa S., Hoon D., Ahn K., Kang K.J., Beuschlein F., Breggia A., Birrer M., Bell D., Borad M., Bryce A.H., Castle E., Chandan V., Cheville J., Copland J.A., Farnell M., Flotte T., Giama N., Ho T., Kendrick M., Kocher J.-P., Kopp K., Moser C., Nagorney D., O'Brien D., O'Neill B.P., Patel T., Petersen G., Que F., Rivera M., Roberts L., Smallridge R., Smyrk T., Stanton M., Thompson R.H., Torbenson M., Yang J.D., Zhang L., Brimo F., Ajani J.A., Gonzalez A.M.A., Behrens C., Bondaruk J., Broaddus R., Czerniak B., Esmaeli B., Fujimoto J., Gershenwald J., Guo C., Logothetis C., Meric-Bernstam F., Moran C., Ramondetta L., Rice D., Sood A., Tamboli P., Thompson T., Troncoso P., Tsao A., Wistuba I., Carter C., Haydu L., Hersey P., Jakrot V., Kakavand H., Kefford R., Lee K., Long G., Mann G., Quinn M., Saw R., Scolyer R., Shannon K., Spillane A., Stretch J., Synott M., Thompson J., Wilmott J., Al-Ahmadie H., Chan T.A., Ghossein R., Gopalan A., Levine D.A., Reuter V., Singer S., Singh B., Tien N.V., Broudy T., Mirsaidi C., Nair P., Drwiega P., Miller J., Smith J., Zaren H., Park J.-W., Hung N.P., Kebebew E., Linehan W.M., Metwalli A.R., Pacak K., Pinto P.A., Schiffman M., Schmidt L.S., Vocke C.D., Wentzensen N., Worrell R., Yang H., Moncrieff M., Goparaju C., Melamed J., Pass H., Botnariuc N., Caraman I., Cernat M., Chemencedji I., Clipca A., Doruc S., Gorincioi G., Mura S., Pirtac M., Stancul I., Tcaciuc D., Albert M., Alexopoulou I., Arnaout A., Bartlett J., Engel J., Gilbert S., Parfitt J., Sekhon H., Thomas G., Rassl D.M., Rintoul R.C., Bifulco C., Tamakawa R., Urba W., Hayward N., Timmers H., Antenucci A., Facciolo F., Grazi G., Marino M., Merola R., de Krijger R., Gimenez-Roqueplo A.-P., Piche A., Chevalier S., McKercher G., Birsoy K., Barnett G., Brewer C., Farver C., Naska T., Pennell N.A., Raymond D., Schilero C., Smolenski K., Williams F., Morrison C., Borgia J.A., Liptay M.J., Pool M., Seder C.W., Junker K., Omberg L., Dinkin M., Manikhas G., Alvaro D., Bragazzi M.C., Cardinale V., Carpino G., Gaudio E., Chesla D., Cottingham S., Dubina M., Moiseenko F., Dhanasekaran R., Becker K.-F., Janssen K.-P., Slotta-Huspenina J., Abdel-Rahman M.H., Aziz D., Bell S., Cebulla C.M., Davis A., Duell R., Elder J.B., Hilty J., Kumar B., Lang J., Lehman N.L., Mandt R., Nguyen P., Pilarski R., Rai K., Schoenfield L., Senecal K., Wakely P., Hansen P., Lechan R., Powers J., Tischler A., Grizzle W.E., Sexton K.C., Kastl A., Henderson J., Porten S., Waldmann J., Fassnacht M., Asa S.L., Schadendorf D., Couce M., Graefen M., Huland H., Sauter G., Schlomm T., Simon R., Tennstedt P., Olabode O., Nelson M., Bathe O., Carroll P.R., Chan J.M., Disaia P., Glenn P., Kelley R.K., Landen C.N., Phillips J., Prados M., Simko J., Smith-McCune K., VandenBerg S., Roggin K., Fehrenbach A., Kendler A., Sifri S., Steele R., Jimeno A., Carey F., Forgie I., Mannelli M., Carney M., Hernandez B., Campos B., 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المصدر: Ding, Li; Bailey, Matthew H; Porta-Pardo, Eduard; Thorsson, Vesteinn; Colaprico, Antonio; Bertrand, Denis; Gibbs, David L; Weerasinghe, Amila; Huang, Kuan-Lin; Tokheim, Collin; Cortés-Ciriano, Isidro; Jayasinghe, Reyka; Chen, Feng; Yu, Lihua; Sun, Sam; Olsen, Catharina; Kim, Jaegil; Taylor, Alison M; Cherniack, Andrew D; Akbani, Rehan; ... (2018). Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell, 173(2), 305-320.e10. Cell Press 10.1016/j.cell.2018.03.033 <http://dx.doi.org/10.1016/j.cell.2018.03.033Test>
Cell, 173 (2
Cell, 173(2), 305. Cell Press
320.e10
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, oncogenic process, INFORMATION, DNA Repair, Tumor Microenvironment/genetics, Carcinogenesis, Cancer Genome Atlas Research Network, medicine.disease_cause, Genome, Biochemistry, Germline, Transcriptome, oncogenic proce, Neoplasms, Databases, Genetic, LS2_1, Tumor Microenvironment, LS4_6, SOMATIC POINT MUTATIONS, 610 Medicine & health, 11 Medical and Health Sciences, Carcinogenesi, Metabolic Networks and Pathways/genetics, cancer genomic, CARCINOGÊNESE, Genomics, TUMORS, Neoplasms/genetics, omics, Proteome, Physique des particules élémentaires, Microsatellite Instability, Life Sciences & Biomedicine, Metabolic Networks and Pathways, Human, EXPRESSION, Biochemistry & Molecular Biology, cancer, cancer genomics, TCGA, omic, Computational biology, Biology, BREAST, CLASSIFICATION, General Biochemistry, Genetics and Molecular Biology, Article, NO, 03 medical and health sciences, DNA Repair/genetics, medicine, Humans, Tumor microenvironment, Science & Technology, LANDSCAPE, IDENTIFICATION, Biochemistry, Genetics and Molecular Biology(all), Metabolic Networks and Pathway, Cell Biology, Epigenome, 06 Biological Sciences, 030104 developmental biology, DISCOVERY, Mutation, DRIVER, Neoplasm, Carcinogenesis/genetics, Developmental Biology, Genetics and Molecular Biology(all), Genes, Neoplasm

وصف الملف: ELETTRONICO; application/pdf; 2 full-text file(s): application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb2ea1af5f5648602e6cd369d82e6a2Test
http://hdl.handle.net/11585/744270Test