نتائج البحث - "Biomedical Science Research Group"

1

Design of a new peptide substrate probe of the putative biomarker legumain with potential application in prostate cancer diagnosis ex vivo

المؤلفون: Neerja Agrawal, Sunil Mathur, Iolia Akaev, Craig Stevens, David John Mincher, Agnes Turnbull, Mridula Chopra

المصدر: Mathur, S, Turnbull, A, Akaev, I, Stevens, C, Agrawal, N, Chopra, M & Mincher, D 2019, ' Design of a new peptide substrate probe of the putative biomarker legumain with potential application in prostate cancer diagnosis ex vivo ', International Journal of Peptide Research and Therapeutics . https://doi.org/10.1007/s10989-019-09994-1Test

مصطلحات موضوعية: Biomedical Science Research Group, genetic structures, synthesis, diagnosis, legumain, Bioengineering, Tripeptide, Legumain, Cleavage (embryo), Biochemistry, Analytical Chemistry, law.invention, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Prostate cancer, Biomarker, Legumain, Diagnosis, Synthesis, law, Drug Discovery, medicine, Microbiology Research Group, Asparagine, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, RCUK, medicine.disease, prostate cancer, Immunology and infection, EPSRC, Enzyme, Health, 030220 oncology & carcinogenesis, biology.protein, Recombinant DNA, Molecular Medicine, biomarker, Ex vivo

وصف الملف: application/pdf; PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a046aa42da455ab82cdbaf6d4298321Test
https://researchportal.port.ac.uk/portal/en/publications/design-of-a-new-peptide-substrate-probe-of-the-putative-biomarker-legumain-with-potential-application-in-prostate-cancer-diagnosis-ex-vivoTest(87b1c347-f4e8-46de-bf6a-3dbd7da456fa).html

2

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy

المؤلفون: Olga Biskou, Kirsty M Hooper, Graham P. Wright, Craig Stevens, Peter G. Barlow, Sadie Kemp, Victor Casanova, Jack Satsangi

المصدر: PLoS ONE, Vol 14, Iss 1, p e0209665 (2019)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Autophagosome, Biomedical Science Research Group, Intermediate Filaments, Vimentin, mTORC1, Membrane Fusion, Biochemistry, Microtubules, chemistry.chemical_compound, 0302 clinical medicine, Cytosol, Contractile Proteins, QR180 Immunology, Cytoskeleton, Staining, Multidisciplinary, biology, Cell Death, Cell Staining, Immunology and infection, Cell biology, medicine.anatomical_structure, Cell Processes, Health, Medicine, Cellular Structures and Organelles, Signal Transduction, Research Article, autophagy, Autophagic Cell Death, Science, macromolecular substances, Mechanistic Target of Rapamycin Complex 1, Research and Analysis Methods, 03 medical and health sciences, lysosomes, 616 Diseases, Tubulins, Lysosome, Cell Line, Tumor, medicine, Humans, Mechanistic target of rapamycin, Withanolides, Organelles, Autophagy, Biology and Life Sciences, Proteins, Cell Biology, Actins, Cytoskeletal Proteins, 030104 developmental biology, HEK293 Cells, chemistry, Withaferin A, Specimen Preparation and Treatment, biology.protein, autophagosomes, 030217 neurology & neurosurgery

وصف الملف: PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bea599e59769fe6734b2e189d71c094Test
https://doi.org/10.1371/journal.pone.0209665Test

3

The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK

المؤلفون: Jack Satsangi, Peter G. Barlow, Victor Casanova, Kirsty M Hooper, Craig Stevens, Katherine Staines, Sadie Kemp, Paul Henderson

المصدر: Hooper, K, Casanova, V, Kemp, S, Staines, K, Satsangi, J, Barlow, P, Henderson, P & Stevens, C 2019, ' The inflammatory bowel disease drug azathioprine induces autophagy via mTORC1 and the unfolded protein response sensor PERK ', Inflammatory Bowel Diseases . https://doi.org/10.1093/ibd/izz039Test

مصطلحات موضوعية: Male, Biomedical Science Research Group, autophagy, Adolescent, medicine.medical_treatment, mTORC1, Mechanistic Target of Rapamycin Complex 1, Inflammatory bowel disease, eIF-2 Kinase, Azathioprine, Escherichia coli, Immunology and Allergy, Medicine, Humans, Microbiology Research Group, Child, ATG16L1, Mechanistic target of rapamycin, Escherichia coli Infections, biology, business.industry, Autophagy, Gastroenterology, unfolded protein response, medicine.disease, Inflammatory Bowel Diseases, Immunology and infection, Adherent-invasive Ecoli, Cytokine, Health, Case-Control Studies, Cancer research, biology.protein, Unfolded protein response, Leukocytes, Mononuclear, RC Internal medicine, Tumor necrosis factor alpha, Female, business, Immunosuppressive Agents, 616.34 Diseases of intestine

وصف الملف: application/pdf; PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec8ba50257a655933da4ef9f9b6b2cdTest
https://hdl.handle.net/20.500.11820/0e5f70bc-5957-4ecc-afc4-5e40b1a258b9Test

4

Immunological homeostasis at the ovine placenta may reflect the degree of maternal fetal interaction

المؤلفون: Sean R. Wattegedera, Laura E. Doull, Mariya I. Goncheva, Nicholas M. Wheelhouse, Donna M. Watson, Julian Pearce, Julio Benavides, Javier Palarea-Albaladejo, Colin J. McInnes, Keith Ballingall, Gary Entrican

المساهمون: Scottish Government's Rural and Environment Science and Analytical Services, European Commission, Bio-Rad Laboratories

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Immunology, Vol 9 (2019)
Frontiers in Immunology
Wattegedera, S R, Doull, L E, Goncheva, M I, Wheelhouse, N M, Watson, D M, Pearce, J, Benavides, J, Palarea-Albaladejo, J, McInnes, C J, Ballingall, K & Entrican, G 2019, ' Immunological Homeostasis at the Ovine Placenta May Reflect the Degree of Maternal Fetal Interaction ', Frontiers in Immunology, vol. 9, pp. 3025 . https://doi.org/10.3389/fimmu.2018.03025Test

مصطلحات موضوعية: 0301 basic medicine, Biomedical Science Research Group, Placenta, Cell, Major histocompatibility complex, Gene Expression, 0302 clinical medicine, Pregnancy, Immunology and Allergy, Homeostasis, QR180 Immunology, Indoleamine 2,3 dioxygenase-1, Maternal-Fetal Exchange, Phylogeny, Original Research, MHC Class I Protein, biology, Trophoblast, Immunology and infection, 3. Good health, Cell biology, Trophoblasts, medicine.anatomical_structure, Health, Reproductive health, Female, lcsh:Immunologic diseases. Allergy, Ovine, Major Histocompatibility Complex, Indoleamine 2, 3 dioxygenase-1, synepitheliochorial placentation, trophoblast, Immunology, synepitheliochorial, rophoblast, Cell Line, Immunophenotyping, Applied microbiology, 03 medical and health sciences, 616 Diseases, MHC class I, medicine, Animals, Microbiology Research Group, Sheep, Synepitheliochorial placentation, Natural Cytotoxicity Triggering Receptor 1, Placentation, Sequence Analysis, DNA, Ovine, 030104 developmental biology, Cell culture, biology.protein, lcsh:RC581-607, Biomarkers, 030215 immunology

وصف الملف: Word; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e988390ab74dbc5105e850403da00b82Test
http://hdl.handle.net/10261/212340Test

5

Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring

المؤلفون: A. Forbes Howie, Desheng Li, Hemin Zhang, Koen Vanderschueren, Jella Wauters, Kirsten S Wilson, Ann Van Soom, Rengui Li, Mick Rae, Tim Bouts, Iain Valentine, Lynn Vanhaecke, Cyrillus Ververs

المساهمون: Yue, Bi-song

المصدر: PLoS ONE
PLOS ONE
PLoS ONE, Vol 13, Iss 7, p e0201420 (2018)
Wauters, J, Wilson, K S, Bouts, T, Valentine, I, Vanderschueren, K, Ververs, C, Howie, A F, Rae, M T, Van Soom, A, Li, R, Li, D, Zhang, H, Vanhaecke, L & Yue, B (ed.) 2018, ' Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring ', PLoS ONE, vol. 13, no. 7, pp. e0201420 . https://doi.org/10.1371/journal.pone.0201420Test

مصطلحات موضوعية: 0301 basic medicine, Biomedical Science Research Group, Physiology, Metabolite, Maternal Health, lcsh:Medicine, Urine, Biochemistry, Physical Chemistry, 0403 veterinary science, SERUM CERULOPLASMIN, chemistry.chemical_compound, Pregnancy, Medicine and Health Sciences, Metabolites, Lipid Hormones, lcsh:Science, Specific Gravity, Progesterone, Mammals, Multidisciplinary, Giant Pandas, Reproduction, Eukaryota, Obstetrics and Gynecology, Ceruloplasmin, 04 agricultural and veterinary sciences, Body Fluids, Chemistry, medicine.anatomical_structure, PREGNANCY, Health, Creatinine, Vertebrates, Physical Sciences, Reproductive health, 590 Animals (Zoology), Female, Anatomy, CREATININE, Ursidae, WILDLIFE, Research Article, Muscle tissue, Captive breeding, Giant Panda, reproductive monitoring, hormone analysis, medicine.medical_specialty, PLASMA-CONCENTRATIONS, 040301 veterinary sciences, Urinary system, Bears, Biology, Urinalysis, 03 medical and health sciences, HORMONE, Internal medicine, medicine, Endocrine system, Animals, Veterinary Sciences, Estrous cycle, lcsh:R, Organisms, Biology and Life Sciences, Estrogens, PROGESTERONE, QL Zoology, Hormones, PGFM, 030104 developmental biology, Endocrinology, PHYSICAL-ACTIVITY, Metabolism, chemistry, Chemical Properties, Amniotes, REFRACTOMETERS, Women's Health, lcsh:Q, Biomarkers, Hormone

وصف الملف: application/pdf; PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a810d65fb6deebf47ea8a347356696fTest
http://europepmc.org/articles/PMC6062134Test

6

Beware biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multi-centre study

المؤلفون: Duncan Muir, Stephanie J. Dancer, K. Ledwoch, K. Kerr, Jean-Yves Maillard, Eshwar Mahenthiralingam, Rebecca Weiser, Jonathan A. Otter, Laura Rushton, D. Roposte

المصدر: The Journal of hospital infection. 100(3)

مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Healthcare associated infections, Biomedical Science Research Group, DNA, Bacterial, 030106 microbiology, Bacillus sp, 030501 epidemiology, medicine.disease_cause, Polymerase Chain Reaction, Microbiology, 03 medical and health sciences, Microbial ecology, Biofilms, environmental microbiology, healthcare, pathogens, healthcare-associated infection, 616 Diseases, DNA, Ribosomal Spacer, Environmental Microbiology, Prevalence, Medicine, Humans, Microbiology Research Group, Multi centre, Bacteriological Techniques, biology, Bacteria, Dehydration, business.industry, Biofilm, General Medicine, QR Microbiology, Sequence Analysis, DNA, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Immunology and infection, Hospitals, United Kingdom, Infectious Diseases, Staphylococcus aureus, Health, Biofilms, Healthcare settings, Microscopy, Electron, Scanning, 0305 other medical science, business

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09d322802295c569f6930058507311eTest
https://pubmed.ncbi.nlm.nih.gov/30026003Test

7

Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release

المؤلفون: Douglas A Gibson, Andrew W Horne, Patrick J Horner, Ioannis Simitsidellis, Sarah E. M. Howie, Philippa T. K. Saunders, Jean Wade, Jeremy K. Brown, Sevi Giakoumelou, Gary Entrican, Nick Wheelhouse

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Giakoumelou, S, Wheelhouse, N, Brown, J, Wade, J, Simitsidellis, I, Gibson, D, Saunders, P, Horner, P, Entrican, G, Howie, S & Horne, A 2017, ' Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release ', Scientific Reports, vol. 7, no. 1, 2001 . https://doi.org/10.1038/s41598-017-02223-zTest
Scientific Reports
Giakoumelou, S, Wheelhouse, N, Brown, J, Wade, J, Simitsidellis, I, Gibson, D, Saunders, P T K, Horner, P, Entrican, G, Howie, S E M & Horne, A W 2017, ' Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release ', Scientific Reports, vol. 7, no. 1, 2001 . https://doi.org/10.1038/s41598-017-02223-zTest

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Biomedical Science Research Group, Chemokine, Proteome, Chlamydia trachomatis, medicine.disease_cause, 0302 clinical medicine, innate immunity, Cells, Cultured, reproductive and urinary physiology, Endometrial Stromal Cell, 030219 obstetrics & reproductive medicine, Multidisciplinary, biology, Decidua, reproductive biology, 618 Gynecology, obstetrics, pediatrics & geriatrics, 3. Good health, medicine.anatomical_structure, Health, Chemokine secretion, RG Gynecology and obstetrics, embryonic structures, Reproductive health, Infectious diseases, Medicine, Female, Chemokines, biological phenomena, cell phenomena, and immunity, Stromal cell, Science, Article, Andrology, Infection, Chlamydia trachomatis, miscarraige, endometrial stromal cell (ESC) decidualisation, chemokines, 03 medical and health sciences, medicine, Humans, CXCL16, Trophoblast, Chlamydia Infections, Immunity, Innate, 030104 developmental biology, Immunology, biology.protein, Stromal Cells

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746f37658132e109a01c9765432bb742Test

8

Cathelicidins display conserved direct antiviral activity towards rhinovirus

المؤلفون: Victor Casanova, Jan Pohl, Peter G. Barlow, Filipa Henderson Sousa, Fern Findlay, Pavel Svoboda, Craig Stevens, Lorna Proudfoot

المصدر: Peptides

مصطلحات موضوعية: 0301 basic medicine, Biomedical Science Research Group, Rhinovirus, Physiology, Swine, medicine.medical_treatment, Cell, Biology, medicine.disease_cause, Biochemistry, Antiviral Agents, Virus, Centre for Nano Safety, Cathelicidin, Microbiology, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Endocrinology, 616 Diseases, Cathelicidins, medicine, Animals, Humans, Microbiology Research Group, Viability assay, QR180 Immunology, Respiratory Tract Infections, Sheep, Respiratory tract infections, LL-37, Epithelial Cells, Blood Proteins, Immunology and infection, 030104 developmental biology, medicine.anatomical_structure, Cathelicidins, rhinovirus, antiviral activity, Apoptosis, Health, 030220 oncology & carcinogenesis, Immunology, Respiratory, lipids (amino acids, peptides, and proteins), Infection, Antimicrobial Cationic Peptides, Research Paper

وصف الملف: PDF

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87858345af0baf1b99f380dc4741b069Test
https://pubmed.ncbi.nlm.nih.gov/28764966Test

9

Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS

المؤلفون: Evangelia Vretou, Stephen Maley, Gary Entrican, Michelle Sait, David Longbottom, Victoria I. Siarkou, Hannah Ensor, Sean Wattegedera, Nick Wheelhouse, Morag Livingstone, Kim Wilson, Kevin Aitchison, Mark P. Dagleish, Mara Rocchi

المساهمون: Vaughan, Lloyd

المصدر: PLoS ONE, Vol 12, Iss 5, p e0177653 (2017)
PLoS ONE
Livingstone, M, Wheelhouse, N, Ensor, H, Rocchi, M, Maley, S, Aitchison, K, Wattegedera, S, Wilson, K, Sait, M, Siarkou, V, Vretou, E, Entrican, G, Dagleish, M, Longbottom, D & Vaughan, L (ed.) 2017, ' Pathogenic outcome following experimental infection of sheep with Chlamydia abortus variant strains LLG and POS ', PLoS ONE, vol. 12, no. 5, pp. e0177653 . https://doi.org/10.1371/journal.pone.0177653Test

مصطلحات موضوعية: Biomedical Science Research Group, 0301 basic medicine, Embryology, Placenta, Antibody Response, lcsh:Medicine, Epitope, Animal Diseases, Chlamydia Infection, 0403 veterinary science, Pathogenesis, Pregnancy, Medicine and Health Sciences, Chlamydia, lcsh:Science, Immune Response, Mammals, Multidisciplinary, biology, Ruminants, QR Microbiology, 04 agricultural and veterinary sciences, Immunohistochemistry, Infectious Diseases, Treatment Outcome, medicine.anatomical_structure, 579 Microorganisms, fungi & algae, Health, Vertebrates, Vagina, Reproductive health, Female, Anatomy, Antibody, Bacterial outer membrane, Research Article, 040301 veterinary sciences, Immunology, Immunoblotting, Sexually Transmitted Diseases, Sheep Diseases, Research and Analysis Methods, Ovine Abortion, Microbiology, Applied microbiology, Gross examination, 03 medical and health sciences, Antigen, Placenta, Ovine abortion, Chlamydia infection, sheep, Chlamydia, Cotyledons (anatomy), Antibody response, immunohistochemistry technics, medicine, Animals, Microbiology Research Group, Immunohistochemistry Techniques, Antigens, Bacterial, Sheep, Bacteria, lcsh:R, Reproductive System, Organisms, Biology and Life Sciences, Cotyledons (Anatomy), Chlamydia Infections, medicine.disease, Virology, Histochemistry and Cytochemistry Techniques, 030104 developmental biology, Amniotes, Immunologic Techniques, biology.protein, lcsh:Q, Zoology, Developmental Biology

وصف الملف: PDF; application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad941be47cc68973d5a401ca15632cf6Test
http://europepmc.org/articles/PMC5426687?pdf=renderTest

10

Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia

المؤلفون: Miguel A. S. Martín-Aragón Baudel, Jennifer Fraser, Amy V. Poole, Mark G. Darlison, Mick Rae

المساهمون: Simos, George

المصدر: PLoS ONE, Vol 12, Iss 10, p e0185664 (2017)
PLoS ONE
Baudel, M A S M-A, Rae, M T, Darlison, M G, Poole, A & Fraser, J 2017, ' Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia ', PLoS ONE, vol. 12, no. 10, e0185664 . https://doi.org/10.1371/journal.pone.0185664Test

مصطلحات موضوعية: Biomedical Science Research Group, 0301 basic medicine, Pulmonology, Cellular differentiation, Retinoic acid, lcsh:Medicine, Vimentin, Vascular Medicine, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Neural Stem Cells, Basic Helix-Loop-Helix Transcription Factors, Medicine and Health Sciences, Hypoxia, lcsh:Science, Neurons, Multidisciplinary, Neuronal Morphology, Protein Stability, Cell Differentiation, Endoplasmic Reticulum Stress, Adaptation, Physiological, Cell Hypoxia, Cell biology, Stroke, Hypoxia-inducible factors, Neurology, RC Internal medicine, Signal transduction, medicine.symptom, Neuronal Differentiation, Signal Transduction, Research Article, Neurite, 616.81 Stroke, Cerebrovascular Diseases, Immunoblotting, Molecular Probe Techniques, Biology, Real-Time Polymerase Chain Reaction, Research and Analysis Methods, 03 medical and health sciences, Stroke, acute hypoxia, neuronal adaptation, Oxygen homeostasis, Medical Hypoxia, medicine, Animals, Humans, Molecular Biology Techniques, Molecular Biology, Ischemic Stroke, lcsh:R, Biology and Life Sciences, Proteins, Cell Biology, Hypoxia (medical), Rats, Cytoskeletal Proteins, 030104 developmental biology, chemistry, nervous system, Cellular Neuroscience, Immunology, biology.protein, lcsh:Q, 030217 neurology & neurosurgery, Developmental Biology, Neuroscience

وصف الملف: PDF; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc44a01f375b36e9429a1e8fd2d24c2eTest
http://europepmc.org/articles/PMC5624621?pdf=renderTest

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