نتائج البحث - "Agostina Nardone"

1

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

المساهمون: De Angelis, C., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., Hilsenbeck, S. G., Benelli, M., Migliaccio, I., Guarducci, C., Malorni, L., Litchfield, L. M., Liu, J., Donaldson, J., Selenica, P., Brown, D. N., Weigelt, B., Reis-Filho, J. S., Park, B. H., Hurvitz, S. A., Slamon, D. J., Rimawi, M. F., Jansen, V. M., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pyridines, Oncology and Carcinogenesis, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, Receptors, Breast Cancer, Genetics, Tumor Cells, Cultured, Humans, Medicine, Oncology & Carcinogenesis, Cancer, Cultured, biology, business.industry, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Estrogen, Immune checkpoint, Tumor Cells, Good Health and Well Being, 030104 developmental biology, Receptors, Estrogen, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Cyclin-dependent kinase 6, Development of treatments and therapeutic interventions, Signal transduction, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d5dea84c01cc54303c5f5ebf7c4dcTest
https://doi.org/10.1158/1078-0432.ccr-19-4191Test

2

FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer

المساهمون: Fu, X., Pereira, R., De Angelis, C., Veeraraghavan, J., Nanda, S., Qin, L., Cataldo, M. L., Sethunath, V., Mehravaran, S., Gutierrez, C., Chamness, G. C., Feng, Q., O'Malley, B. W., Selenica, P., Weigelt, B., Reis-Filho, J. S., Cohen, O., Wagle, N., Nardone, A., Jeselsohn, R., Brown, M., Rimawi, M. F., Osborne, C. K., Schiff, R.

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Multidisciplinary, Chromatin binding, Pioneer factor, Enhancer/transcriptional reprogramming, Biological Sciences, Biology, medicine.disease, Metastatic breast cancer, Metastasis, Breast cancer, Cancer research, medicine, FOXA1, Transcription factor, Reprogramming, Endocrine resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524cedf1e32bed7312ca09dcdb1188ecTest
https://doi.org/10.1073/pnas.1911584116Test

3

Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity

المؤلفون: Xiaoyong Fu, Radhika D. Dandekar, Maureen G. Mancini, Rachel Schiff, Suzanne A. W. Fuqua, Guowei Gu, Carmine De Angelis, Agostina Nardone, Fabio Stossi, Clifford Stephan, Hans E. Johansson, Mark T. Bedford, Michael A. Mancini, Wei Xu

المساهمون: Stossi, Fabio, D Dandekar, Radhika, G Mancini, Maureen, Gu, Guowei, W Fuqua, Suzanne A, Nardone, Agostina, DE ANGELIS, Carmine, Fu, Xiaoyong, Schiff, Rachel, T Bedford, Mark, Xu, Wei, E Johansson, Han, C Stephan, Clifford, A Mancini, Michael

المصدر: Nucleic Acids Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7ce7b2aa4beefcace2eb49798c5df5Test
https://hdl.handle.net/11588/891821Test

4

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy

المساهمون: Giuliano, Mario, Hu, H, Wang, Yc, Fu, X, Nardone, Agostina, Herrera, S, Mao, S, Contreras, A, Gutierrez, C, Wang, T, Hilsenbeck, Sg, DE ANGELIS, Carmine, Wang, Nj, Heiser, Lm, Gray, Jw, Lopez Tarruella, S, Pavlick, Ac, Trivedi, Mv, Chamness, Gc, Chang, Jc, Osborne, Ck, Rimawi, Mf, Schiff, R.

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Antineoplastic Agents, Hormonal, Cell Survival, Receptor, ErbB-2, medicine.medical_treatment, Gene Expression, Estrogen receptor, Breast Neoplasms, Lapatinib, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Internal medicine, Animals, Humans, Medicine, Molecular Targeted Therapy, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, biology, Fulvestrant, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Neoadjuvant Therapy, Disease Models, Animal, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Tumor progression, Quinazolines, Cancer research, biology.protein, Female, Receptors, Progesterone, business, Biomarkers, Signal Transduction, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b1598f486d1beb5e4551a1d1f12f3dTest
https://doi.org/10.1158/1078-0432.ccr-14-2728Test

5

Abstract PD7-01: Identification of a high FOXA1-induced pro-metastatic enhancer signature in endocrine-resistant and metastatic breast cancer

المؤلفون: Carmine De Angelis, Resel Pereira, C. Kent Osborne, Lanfang Qin, Rinath Jeselsohn, Britta Weigelt, Mothaffar F. Rimawi, Jamunarani Veeraraghavan, Agostina Nardone, Pier Selenica, Rachel Schiff, Myles Brown, Xiaoyong Fu, Jorge S. Reis-Filho, Sarmistha Nanda

المصدر: Cancer Research. 80:PD7-01

مصطلحات موضوعية: Cancer Research, Chromatin binding, Cancer, Biology, medicine.disease, medicine.disease_cause, Oncology, Cistrome, Cancer research, medicine, Epigenetics, FOXA1, Enhancer, Carcinogenesis, Transcription factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::6544a61192b7cedfec9ae36c0c847aedTest
https://doi.org/10.1158/1538-7445.sabcs19-pd7-01Test

6

Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Cistrome, Cancer research, Wild type, Estrogen receptor, FOXA1, Biology, Estrogen receptor alpha, Gene, Phenotype, Chromatin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::204df0332dfb01b0dbe3c9006951133dTest
https://doi.org/10.2139/ssrn.3155601Test

7

Cytometric and biochemical characterization of human breast cancer cells reveals heterogeneous myoepithelial phenotypes

المؤلفون: Sara Corvigno, Felicia Leccia, Sabino De Placido, Francesco Salvatore, Luigi Del Vecchio, Agostina Nardone, Bianca Maria Veneziani

المساهمون: Felicia, Leccia, Agostina, Nardone, Sara, Corvigno, DEL VECCHIO, Luigi, DE PLACIDO, Sabino, Francesco, Salvatore, Veneziani, BIANCA MARIA

المصدر: Cytometry Part A. :960-972

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ec4956e2332911459741f1c1a892b6Test
https://doi.org/10.1002/cyto.a.22095Test

8

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

المساهمون: Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L. M., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J., Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J. W., Weigelt, B., Reis-Filho, J. S., Osborne, C. K., Schiff, R.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Xenograft Model Antitumor Assay, Receptor, ErbB-2, Afatinib, medicine.medical_treatment, Breast Neoplasms, Biology, Lapatinib, Antibodies, Monoclonal, Humanized, Article, Targeted therapy, 03 medical and health sciences, Mice, 0302 clinical medicine, Germline mutation, Breast cancer, Trastuzumab, Cell Line, Tumor, medicine, Animals, Humans, Molecular Targeted Therapy, skin and connective tissue diseases, Cell Proliferation, Animal, Cancer, Quinazoline, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, Receptors, Estrogen, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Immunology, Neratinib, Mutation, Cancer research, Quinazolines, Female, Breast Neoplasm, medicine.drug, Human, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb068280b301594f2965d31acd31789Test
https://europepmc.org/articles/PMC5762201Test/

9

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

المؤلفون: Nicholas Mitsiades, Rainer B. Lanz, Cristian Coarfa, Chad J. Creighton, Zheng Zhang, Yongcheng Song, Xiaoyong Fu, Bert W. O'Malley, C. Kent Osborne, Qin Feng, Constantine S. Mitsiades, Bin He, Agostina Nardone, James E. Bradner, Martin Shea, Rachel Schiff, Lei Wang, Susan G. Hilsenbeck

المصدر: Cell Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c16f2d3cdf58d637fb10ef1da2be07Test
https://doi.org/10.1038/cr.2014.71Test

10

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

المساهمون: Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V., Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K., Schiff, R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(43)

مصطلحات موضوعية: 0301 basic medicine, Hepatocyte Nuclear Factor 3-alpha, Antineoplastic Agents, Hormonal, Prognosi, Estrogen receptor, Breast Neoplasms, Biology, Transcriptome, 03 medical and health sciences, Breast cancer, Cell Line, Tumor, medicine, Humans, RNA, Small Interfering, Gene knockdown, Multidisciplinary, Pioneer factor, Interleukin-8, Estrogen Receptor alpha, medicine.disease, Prognosis, Survival Analysis, Gene Expression Regulation, Neoplastic, Tamoxifen, 030104 developmental biology, PNAS Plus, Drug Resistance, Neoplasm, Transcriptional reprogramming, Cancer research, Female, Survival Analysi, FOXA1, Estrogen receptor alpha, Breast Neoplasm, Endocrine resistance, Human, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2387c3c513051ae7743e2ef46a0318Test
https://pubmed.ncbi.nlm.nih.gov/27791031Test

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