المؤلفون: Guoyong Ren, Fei Yang, Bin Wu, Xuemei Wu, Pan Xue

المصدر: Aging (Albany NY)

مصطلحات موضوعية: Olfactory system, Aging, Neurogenesis, Hippocampus, Pharmacology, Hippocampal formation, CREB, Glucagon-Like Peptide-1 Receptor, Elevated Plus Maze Test, Mice, Olfaction Disorders, Lixisenatide, chemistry.chemical_compound, Animals, Medicine, Olfactory memory, Cyclic AMP Response Element-Binding Protein, Administration, Intranasal, Depressive Disorder, Behavior, Animal, biology, Depression, business.industry, olfactory function, Cell Biology, Olfactory Bulb, Disease Models, Animal, Hindlimb Suspension, chemistry, biology.protein, Antidepressant, Peptides, business, lixisenatide, Open Field Test, Stress, Psychological, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5925aed387a757b8f14aa30b44360eacTest
https://doi.org/10.18632/aging.202358Test

المؤلفون: Alexandre Roulin, Karin Löw, Stefan Kunz

المصدر: FEBS Letters. 594:2840-2866

مصطلحات موضوعية: Pro-Opiomelanocortin, Biophysics, Gene Expression, Peptide, Peptide hormone, Cleavage (embryo), Biochemistry, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, chemistry.chemical_compound, Proopiomelanocortin, Structural Biology, Blood plasma, Cyclic AMP, Genetics, Humans, Protein Isoforms, Receptors, Neurotensin, Amino Acid Sequence, Melanocyte-Stimulating Hormones, Molecular Biology, Peptide sequence, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Sequence Homology, Amino Acid, biology, Protein Stability, 030302 biochemistry & molecular biology, Membrane Proteins, Cell Biology, HEK293 Cells, chemistry, biology.protein, Peptides, Receptor, Melanocortin, Type 1, Sequence Alignment, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Neurotensin, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a9f2240688ff80324ef2cfcd6fc2b2Test
https://doi.org/10.1002/1873-3468.13855Test

المؤلفون: Yeon Woong Chung, Ji Young Lee, Jin A Choi, Jae-Hyung Lee, Seung Hyun Ko, Hyun Hee Ju, Ye-Jee Lee, Dong Hyun Jee

المصدر: The American Journal of Pathology. 190:1080-1094

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, genetic structures, medicine.drug_class, Anti-Inflammatory Agents, Nerve fiber, Glucagon-Like Peptide-1 Receptor, Retina, Diabetes Mellitus, Experimental, Pathology and Forensic Medicine, Mice, 03 medical and health sciences, Lixisenatide, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Animals, Hypoglycemic Agents, Medicine, Diabetic Retinopathy, Glial fibrillary acidic protein, biology, business.industry, Diabetic retinopathy, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Inner nuclear layer, 030221 ophthalmology & optometry, Optic nerve, biology.protein, sense organs, Peptides, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d7a6de97da4c20751f8f596a2d2bfcTest
https://doi.org/10.1016/j.ajpath.2020.01.011Test

المؤلفون: Jing Han, Yuqing Sun, Feng Zhou, Lidan Sun, Qimeng Yang, Chun Han, Lintao Wu, Xinyu Chen

المصدر: Molecular pharmaceutics. 18(8)

مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Xenopus, Serum albumin, Pharmaceutical Science, Peptide, CHO Cells, Pharmacology, Diet, High-Fat, Glucagon, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, Mice, Cricetulus, In vivo, Glucagon-Like Peptide 1, Drug Discovery, Weight Loss, medicine, Receptors, Glucagon, Animals, Humans, Obesity, Receptor, chemistry.chemical_classification, Mice, Inbred ICR, biology, Chemistry, Glucagon-like peptide-1, Rats, Mice, Inbred C57BL, Disease Models, Animal, Treatment Outcome, biology.protein, Molecular Medicine, Peptides, Glucagon receptor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c1485d74fda2eaeabef0ea943db742Test
https://pubmed.ncbi.nlm.nih.gov/34240881Test

المؤلفون: Caroline A. Hick, Juan Carlos Mobarec, Patrick M. Sexton, Thomas P. Sakmar, Cassandra Koole, Christopher A. Reynolds

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, photocross-linking, Peptide, Ligands, Biochemistry, structure-function, 0302 clinical medicine, Cyclic AMP, structural biology, 5-HT5A receptor, Receptor, chemistry.chemical_classification, Molecular Structure, genetic code expansion, Protein Structure and Folding, glucagon-like peptide-1 receptor (GLP-1R), Azides, Ultraviolet Rays, Phenylalanine, Protein domain, G protein-coupled receptor (GPCR), Biology, Molecular Dynamics Simulation, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, Structure-Activity Relationship, Protein Domains, Humans, unnatural amino acid, GABBR2, GABBR1, Molecular Biology, G protein-coupled receptor, Binding Sites, peptide hormone, molecular modeling, Venoms, Cell Biology, 030104 developmental biology, HEK293 Cells, Structural biology, chemistry, Diabetes Mellitus, Type 2, Mutagenesis, Mutation, Biophysics, Exenatide, Protein Multimerization, Peptides, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf16e26034aacee8551f6377dd783e8Test
http://europepmc.org/articles/PMC5409479Test

المؤلفون: Peter R. Flatt, Galyna V. Graham, Chris M. McLaughlin

المصدر: Diabetes, obesitymetabolismREFERENCES. 22(12)

مصطلحات موضوعية: biology, business.industry, Venoms, Endocrinology, Diabetes and Metabolism, Lizards, Bioinformatics, biology.organism_classification, Glucagon-like peptide-1, Glucagon-Like Peptide-1 Receptor, Peptide Fragments, Endocrinology, Glucagon-Like Peptide 1, Internal Medicine, Gila monster, Medicine, Animals, Exenatide, Humans, business, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cddc3958971b5074b8ca5b153986cffTest
https://pubmed.ncbi.nlm.nih.gov/33462968Test

المؤلفون: Thomas Egebjerg, Steffen Reedtz-Runge, Christopher J. Langmead, Hari Venugopal, Peishen Zhao, Sheng Y. Ang, Radostin Danev, Patrick M. Sexton, Gregory D. Stewart, David E. Gloriam, Alisa Glukhova, Tin T. Truong, Sebastian G.B. Furness, Christina Rye Underwood, Xin Zhang, Albert J. Kooistra, Laurence J. Miller, Arthur Christopoulos, Petr Šenel, Yi Lynn Liang, Matthew J. Belousoff, Denise Wootten

المصدر: Zhang, X, Belousoff, M J, Zhao, P, Kooistra, A J, Truong, T T, Ang, S Y, Underwood, C R, Egebjerg, T, Šenel, P, Stewart, G D, Liang, Y-L, Glukhova, A, Venugopal, H, Christopoulos, A, Furness, S G B, Miller, L J, Reedtz-Runge, S, Langmead, C J, Gloriam, D E, Danev, R, Sexton, P M & Wootten, D 2020, ' Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists ', Molecular Cell, vol. 80, no. 3, pp. 485-500 . https://doi.org/10.1016/j.molcel.2020.09.020Test

مصطلحات موضوعية: Agonist, medicine.drug_class, High resolution, Peptide, Biology, Non peptide, Glucagon-Like Peptide-1 Receptor, Receptors, G-Protein-Coupled, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Functional selectivity, Extracellular, medicine, Animals, Humans, Structure–activity relationship, Binding site, Receptor, Molecular Biology, 030304 developmental biology, G protein-coupled receptor, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Chemistry, Cryoelectron Microscopy, Cell Biology, Cell biology, Peptides, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf3e93793c5fecfb5c14acdfc4376a4Test
https://curis.ku.dk/portal/da/publications/differential-glp1r-binding-and-activation-by-peptide-and-nonpeptide-agonistsTest(d15f7c32-33ae-43b2-9d9d-b3809a50eb78).html

المؤلفون: Thomas P. Cappola, Laurie L. Baggio, Kenneth B. Margulies, Jagdish Butany, Erin E. Mulvihill, Catherine J. Streutker, Daniel J. Drucker, Xiemin Cao, Bernardo Yusta

المصدر: Endocrinology. 159:1570-1584

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Myocytes, Smooth Muscle, In situ hybridization, 030204 cardiovascular system & hematology, Biology, Glucagon-Like Peptide-1 Receptor, Muscle, Smooth, Vascular, Cell Line, Islets of Langerhans, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Cricetinae, Internal medicine, medicine, Animals, Humans, Myocyte, Research Articles, Cellular localization, Messenger RNA, Sinoatrial node, Myocardium, Pancreatic islets, Heart, Fibroblasts, Molecular biology, 3. Good health, Reverse transcription polymerase chain reaction, 030104 developmental biology, medicine.anatomical_structure, Real-time polymerase chain reaction, Glucagon-Like Peptide-2 Receptor, Female, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b5aa839e5332e5acf71aeb550d0a92Test
https://doi.org/10.1210/en.2018-00004Test

المؤلفون: Keisuke Kimura, Jiawei Qi, Hideki Kitaura, Haruki Sugisawa, Akiko Kishikawa, Kazuhiro Shima, Masahiko Ishida, Wei Ren Shen, Saika Ogawa

المصدر: Journal of Immunology Research
Journal of Immunology Research, Vol 2018 (2018)

مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Anti-Inflammatory Agents, Osteoclasts, Mice, 0302 clinical medicine, Immunology and Allergy, Receptor, Cells, Cultured, biology, Chemistry, digestive, oral, and skin physiology, Cell Differentiation, General Medicine, medicine.anatomical_structure, RANKL, lipids (amino acids, peptides, and proteins), Tumor necrosis factor alpha, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, Research Article, lcsh:Immunologic diseases. Allergy, musculoskeletal diseases, Agonist, endocrine system, medicine.medical_specialty, Article Subject, medicine.drug_class, Immunology, 030209 endocrinology & metabolism, Inflammation, Glucagon-Like Peptide-1 Receptor, Bone resorption, 03 medical and health sciences, Osteoclast, Internal medicine, medicine, Animals, Bone Resorption, Glucagon-like peptide 1 receptor, Tumor Necrosis Factor-alpha, Venoms, Macrophages, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, biology.protein, Exenatide, lcsh:RC581-607, Peptides

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cc6180f5bd6b51db956a01f0997ab8Test
https://doi.org/10.1155/2018/5783639Test

المؤلفون: Jun Zhang, Zhao-Jun Wang, Wei Yang, Jin-Shun Qi, Mei-Na Wu, Yang Junting, Hong-Yan Cai

المصدر: Biochemical and Biophysical Research Communications. 495:1034-1040

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, Biophysics, Mice, Transgenic, Biochemistry, Neuroprotection, Glucagon-Like Peptide-1 Receptor, Amyloid beta-Protein Precursor, Mice, 03 medical and health sciences, Lixisenatide, chemistry.chemical_compound, 0302 clinical medicine, Alzheimer Disease, Internal medicine, mental disorders, Animals, Medicine, Senile plaques, Receptor, Molecular Biology, Neuroinflammation, Dose-Response Relationship, Drug, biology, business.industry, Neurofibrillary Tangles, Cell Biology, Mice, Inbred C57BL, Insulin receptor, Neuroprotective Agents, Treatment Outcome, 030104 developmental biology, Endocrinology, chemistry, Synaptic plasticity, biology.protein, Encephalitis, Female, Peptides, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd10fa6286633924382a8c3e780041Test
https://doi.org/10.1016/j.bbrc.2017.11.114Test