المؤلفون: Joshua W. K. Ho, Richard I. Sherwood, Tomasz Szczesnik

المصدر: Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-11 (2019)
Epigenetics & Chromatin

مصطلحات موضوعية: Site-Specific DNA-Methyltransferase (Adenine-Specific), lcsh:QH426-470, Mutant, Computational biology, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Dam methylase, Gene expression, Genetics, Animals, Molecular Biology, Transcription factor, Embryonic Stem Cells, 030304 developmental biology, 0303 health sciences, Binding Sites, Dam, Methodology, DNA, Genomics, Sequence Analysis, DNA, Methylation, DNA Methylation, Chromatin, DNA-Binding Proteins, genomic DNA, lcsh:Genetics, Mutation, DamID, Transcription Factor 7-Like 2 Protein, TCF7L2, 030217 neurology & neurosurgery, Protein Binding, Transcription Factors, Tcf7l2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fccc8ca0cf4eea3a8c01a8bc3b6ee5Test
http://link.springer.com/article/10.1186/s13072-019-0273-xTest

المؤلفون: Katarzyna A. Lisowska, Zbigniew Zdrojewski, Michał Pikuła, Żaneta Smoleńska, Anna Wardowska

المصدر: Acta biochimica Polonica. 67(3)

مصطلحات موضوعية: Adult, Male, Myeloid, medicine.medical_treatment, Tumor Necrosis Factor Ligand Superfamily Member 13, Polymerase Chain Reaction, Severity of Illness Index, General Biochemistry, Genetics and Molecular Biology, Immune tolerance, Pathogenesis, medicine, Humans, Lupus Erythematosus, Systemic, Myeloid Cells, skin and connective tissue diseases, Autoimmune disease, biology, business.industry, Autoantibody, Dendritic Cells, Middle Aged, medicine.disease, Flow Cytometry, DNA-Binding Proteins, Cytokine, medicine.anatomical_structure, Phenotype, Case-Control Studies, Immunology, Interferon Regulatory Factors, biology.protein, Female, Antibody, business, Transcriptome, Transcription Factor 7-Like 2 Protein, IRF5

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b02decc3a5f608dd2301d239fa2f283Test
https://pubmed.ncbi.nlm.nih.gov/32730703Test

المؤلفون: Jeffrey N. Savas, Elizabeth T. Bartom, Lu Wang, Caila Ryan, Zibo Zhao, Ali Shilatifard, Navdeep S. Chandel, Stacy A. Marshall, Anthony Shilati, Emily J. Rendleman

المصدر: Science Advances

مصطلحات موضوعية: endocrine system, animal structures, endocrine system diseases, Apoptosis, Biology, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Gene expression, Transcriptional regulation, Humans, Research Articles, beta Catenin, Cancer, 030304 developmental biology, Regulation of gene expression, Glucose Transporter Type 1, 0303 health sciences, Multidisciplinary, Chromatin binding, Wnt signaling pathway, nutritional and metabolic diseases, SciAdv r-articles, Up-Regulation, 3. Good health, Cell biology, Chromatin, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Repressor Proteins, Glucose, 030220 oncology & carcinogenesis, Catenin, Colonic Neoplasms, Signal transduction, Glycolysis, Transcription Factor 7-Like 2 Protein, hormones, hormone substitutes, and hormone antagonists, Research Article, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481caa9166812bcd1b92f75a60d6179cTest
https://doi.org/10.1126/sciadv.aax0698Test

المؤلفون: Daniel V. LaBarbera, Frederick A Valeriote, Adedoyin D. Abraham, Qiong Zhou, Daniel L. Gustafson, Linfeng Li, A Babalmorad, Stacey M. Bagby, John J. Arcaroli, J Schaack, Wells A. Messersmith, R J Hansen

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Chromatin Immunoprecipitation, Cancer Research, Epithelial-Mesenchymal Transition, Biology, DNA-binding protein, Molecular oncology, 03 medical and health sciences, Antigens, Neoplasm, Transcription (biology), Cell Line, Tumor, Genetics, Humans, Neoplasm Invasiveness, Protein Interaction Maps, Epithelial–mesenchymal transition, Neoplasm Metastasis, Molecular Biology, beta Catenin, Cell Proliferation, Wnt signaling pathway, Promoter, TCF4, Molecular biology, Neoplasm Proteins, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, DNA Topoisomerases, Type II, 030104 developmental biology, Colonic Neoplasms, embryonic structures, Cancer research, Original Article, Transcription Factor 7-Like 2 Protein, Chromatin immunoprecipitation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbaea30fb50e149a5b2005009eff4bdTest
https://doi.org/10.1038/onc.2016.29Test

المؤلفون: Mehmet Coskun, Eric P. Bennett, Katja Dahlgaard, Ismail Gögenur, Jesper T. Troelsen, Sylvester Larsen, Johanne Davidsen

المصدر: PLoS ONE
Davidsen, J, Larsen, S, Coskun, M, Gögenur, I, Dahlgaard, K, Bennett, E P & Troelsen, J T 2018, ' The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2 ', PLoS ONE, vol. 13, no. 7, e0200215 . https://doi.org/10.1371/journal.pone.0200215Test
PLoS ONE, Vol 13, Iss 7, p e0200215 (2018)

مصطلحات موضوعية: 0301 basic medicine, Oncogene Proteins, Fusion, Molecular biology, lcsh:Medicine, Gene Expression, Biochemistry, Fusion gene, Cell Fusion, 0302 clinical medicine, Cell Signaling, Genes, Reporter, Transcriptional regulation, Medicine and Health Sciences, CDX2 Transcription Factor, CDX2, lcsh:Science, Promoter Regions, Genetic, Wnt Signaling Pathway, beta Catenin, WNT Signaling Cascade, Multidisciplinary, Wnt signaling pathway, TCF4, Qb-SNARE Proteins, Signaling Cascades, Cell biology, Enzymes, Intestines, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, Anatomy, Oxidoreductases, Transcription Factor 7-Like 2 Protein, Luciferase, Research Article, Signal Transduction, Cell Physiology, Colon, Biology, DNA construction, 03 medical and health sciences, Cell Line, Tumor, DNA-binding proteins, Genetics, Humans, Gene Regulation, Transcription factor, Colorectal Cancer, Binding Sites, lcsh:R, Biology and Life Sciences, Cancers and Neoplasms, Proteins, Cell Biology, Fusion protein, Regulatory Proteins, Gastrointestinal Tract, Research and analysis methods, 030104 developmental biology, Molecular biology techniques, Plasmid Construction, Enzymology, lcsh:Q, TCF7L2, Digestive System, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b091b3f7f92a11aa39f9543a12f8659Test
https://pubmed.ncbi.nlm.nih.gov/29975781Test

المؤلفون: Struan F.A. Grant, Sandra Deliard, Matthew E. Johnson, Qianghua Xia, Chao-Xing Yuan

المصدر: European Journal of Human Genetics. 23:103-109

مصطلحات موضوعية: Transcription, Genetic, endocrine system diseases, Poly (ADP-Ribose) Polymerase-1, Locus (genetics), Plasma protein binding, Article, Cell Line, Tumor, Genetics, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Allele, Gene, Alleles, Genetics (clinical), Polymerase, Regulation of gene expression, biology, Intron, nutritional and metabolic diseases, RNA Helicase A, DNA-Binding Proteins, Diabetes Mellitus, Type 2, Gene Expression Regulation, Mutation, biology.protein, Poly(ADP-ribose) Polymerases, Transcription Factor 7-Like 2 Protein, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d06b65465a61ef0a7bc1fd8448dc0a2Test
https://doi.org/10.1038/ejhg.2014.48Test

المؤلفون: Boris Schmitz, Michael Schelleckes, Joachim Kremerskothen, Eva Brand, Katrin Guske, Stefan-Martin Brand, Hermann Pavenstädt, Kerstin Duning

المصدر: Journal of Molecular Medicine. 92:185-196

مصطلحات موضوعية: Chromatin Immunoprecipitation, Transcription, Genetic, Muscle Proteins, Biology, Kidney, medicine.disease_cause, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Cell Line, Neuroblastoma, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, Gene expression, medicine, Transcriptional regulation, Humans, Promoter Regions, Genetic, Gene, Transcription factor, Genetics (clinical), Adaptor Proteins, Signal Transducing, 030304 developmental biology, Genetics, Regulation of gene expression, 0303 health sciences, Hippo signaling pathway, Intracellular Signaling Peptides and Proteins, TEA Domain Transcription Factors, Epithelial Cells, YAP-Signaling Proteins, Promoter, Exons, Phosphoproteins, Introns, DNA-Binding Proteins, Alternative Splicing, Gene Expression Regulation, Molecular Medicine, Transcription Initiation Site, Carcinogenesis, Transcription Factor 7-Like 2 Protein, 030217 neurology & neurosurgery, Protein Binding, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751c1d98013577ced360073fccb78faTest
https://doi.org/10.1007/s00109-013-1089-yTest

المؤلفون: Zemin Zhang, David A. Largaespada, Subhra Chaudhuri, Weiru Wang, Thomas D. Wu, Vasantharajan Janakiraman, Steffen Durinck, Jeremy Stinson, Connie Ha, Jeremiah D. Degenhardt, Gerrit J. P. Dijkgraaf, Caitlin B. Conboy, Peter M. Haverty, Eric Stawiski, Robert Gentleman, Richard Bourgon, Bijay S. Jaiswal, Melanie A. Huntley, Hartmut Koeppen, Joseph Guillory, Zora Modrusan, Yinghui Guan, Elaine E. Storm, Florian Gnad, Somasekar Seshagiri, Timothy K. Starr, Frederic J. de Sauvage

المصدر: Nature. 488:660-664

مصطلحات موضوعية: Genes, APC, DNA Copy Number Variations, Receptor, ErbB-3, Colorectal cancer, Molecular Sequence Data, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Protein Serine-Threonine Kinases, Gene mutation, medicine.disease_cause, Polymorphism, Single Nucleotide, Article, Receptor tyrosine kinase, Dioxygenases, Insulin-Like Growth Factor II, Proto-Oncogene Proteins, medicine, Humans, Exome, RSPO2, Genetics, Multidisciplinary, Base Sequence, biology, Sequence Analysis, RNA, Gene Expression Profiling, Tumor Suppressor Proteins, Wnt signaling pathway, medicine.disease, Fusion protein, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Wnt Proteins, Gene expression profiling, Colonic Neoplasms, Mutation, biology.protein, Intercellular Signaling Peptides and Proteins, Gene Fusion, Thrombospondins, Carcinogenesis, Transcription Factor 7-Like 2 Protein, Genes, Neoplasm, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4cbf3cd2d7e16d875a913cf836256aTest
https://doi.org/10.1038/nature11282Test

المؤلفون: Michio Kosugi, Hasan Rajabi, Maya Datt Joshi, Caining Jin, Maroof Alam, Donald Kufe, Rehan Ahmad

المصدر: Journal of Biological Chemistry. 287:10703-10713

مصطلحات موضوعية: Cyclin E, Transcription, Genetic, Cyclin D, Cyclin A, Cyclin B, Breast Neoplasms, P300-CBP Transcription Factors, Biology, digestive system, Biochemistry, Cyclin D1, Cell Line, Tumor, Humans, p300-CBP Transcription Factors, Gene Regulation, skin and connective tissue diseases, neoplasms, Molecular Biology, beta Catenin, Mucin-1, Cell Biology, biological factors, digestive system diseases, Protein Structure, Tertiary, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Alcohol Oxidoreductases, Cancer research, biology.protein, Cyclin-dependent kinase complex, Female, Transcription Factor 7-Like 2 Protein, Cyclin A2, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2619a68ab9ea73b5e410f7ee6fbfd31Test
https://doi.org/10.1074/jbc.m111.323311Test

المؤلفون: Alena Stančáková, Tiina Kuulasmaa, Jussi Pihlajamäki, Markku Laakso, Teemu Kuulasmaa, Eleuterio Ferrannini, Jussi Paananen, Johanna Kuusisto, Jagadish Vangipurapu

المصدر: Diabetologia. 54:563-571

مصطلحات موضوعية: Male, Tetraspanins, Endocrinology, Diabetes and Metabolism, Cell Cycle Proteins, Type 2 diabetes, chemistry.chemical_compound, Polymorphism (computer science), Adipocyte, Adipocytes, Receptor, Notch2, Receptor, Cation Transport Proteins, Finland, tRNA Methyltransferases, Membrane Glycoproteins, RNA-Binding Proteins, Middle Aged, Neoplasm Proteins, DNA-Binding Proteins, Liver, Zinc Transporter 8, Co-Repressor Proteins, Transcription Factor 7-Like 2 Protein, medicine.medical_specialty, ADAMTS9 Protein, Biology, Polymorphism, Single Nucleotide, Insulin resistance, Antigens, Neoplasm, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Potassium Channels, Inwardly Rectifying, Cyclin-Dependent Kinase Inhibitor p15, Hepatocyte Nuclear Factor 1-beta, Homeodomain Proteins, Membrane Proteins, Cyclin-Dependent Kinase 5, medicine.disease, TRNA Methyltransferases, PPAR gamma, ADAM Proteins, Endocrinology, Diabetes Mellitus, Type 2, chemistry, Insulin Resistance, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b7cc57c462f044475d74bab35e1ff8Test
https://doi.org/10.1007/s00125-010-1977-4Test