التفاصيل البيبلوغرافية
| العنوان: |
Self-Renewal of Single Mouse Hematopoietic Stem Cells Is Reduced by JAK2V617F Without Compromising Progenitor Cell Expansion. |
| المؤلفون: |
Kent, David G., Li, Juan, Tanna, Hinal, Fink, Juergen, Kirschner, Kristina, Pask, Dean C., Silber, Yvonne, Hamilton, Tina L., Sneade, Rachel, Simons, Benjamin D., Green, Anthony R. |
| المصدر: |
PLoS Biology; Jun2013, Vol. 11 Issue 6, p1-15, 15p |
| مصطلحات موضوعية: |
MICE, HEMATOPOIETIC stem cells, BLOOD cells, PROGENITOR cells, CELLS |
| مستخلص: |
: In this study, single cell assays and mathematical modeling demonstrate that a single oncogenic point mutation can negatively affect hematopoietic stem cells while leaving progenitor cell expansion intact. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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