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المؤلفون: Kun-Liang Guan, Da-Hye Lee, Ja Hyun Koo, Cun-Yu Wang, Dae-Sik Lim, Di Yang, Steven W. Plouffe, Zhipeng Meng
المصدر: Genes Dev
Genes & development, vol 34, iss 1-2مصطلحات موضوعية: Uveal Neoplasms, medicine.disease_cause, Medical and Health Sciences, Mice, 0302 clinical medicine, Hippo, Transcription (biology), 2.1 Biological and endogenous factors, Aetiology, Promoter Regions, Genetic, Melanoma, Tissue homeostasis, 0303 health sciences, Tumor, Adaptor Proteins, Genes, fos, Organ Size, Biological Sciences, Cell biology, Gene Expression Regulation, Neoplastic, Liver, 030220 oncology & carcinogenesis, Stem Cell Research - Nonembryonic - Non-Human, bilirubin, Biotechnology, Research Paper, c-fos, fos, Biology, liver, Cell Line, Promoter Regions, 03 medical and health sciences, hepatomegaly, Rare Diseases, Genetic, Cell Line, Tumor, Genetics, medicine, cancer, Animals, Humans, Transcription factor, Adaptor Proteins, Signal Transducing, Cell Proliferation, 030304 developmental biology, Neoplastic, Hippo signaling pathway, Cell growth, Human Genome, Psychology and Cognitive Sciences, Signal Transducing, YAP-Signaling Proteins, Promoter, Stem Cell Research, Transcription Factor AP-1, HEK293 Cells, Gene Expression Regulation, Genes, Transcriptional Coactivator with PDZ-Binding Motif Proteins, Cancer cell, Trans-Activators, Mitogens, Carcinogenesis, Gene Deletion, Transcription Factors, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4932433e75f0c2b2317020a98402584Test
https://doi.org/10.1101/gad.331546.119Test -
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المؤلفون: Kun-Liang Guan, Zhipeng Meng, Toshiro Moroishi
المصدر: Genes & development, vol 30, iss 1
مصطلحات موضوعية: Enzymologic, TAZ, 0301 basic medicine, endocrine system, animal structures, 1.1 Normal biological development and functioning, LATS, Review, Protein Serine-Threonine Kinases, Biology, Medical and Health Sciences, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Underpinning research, Cell polarity, Genetics, Animals, Humans, TEAD1, Transcription factor, MST, Hippo signaling pathway, MAP4K, TEAD, Cell growth, Psychology and Cognitive Sciences, fungi, Biological Sciences, Actin cytoskeleton, Cell biology, body regions, Drosophila melanogaster, 030104 developmental biology, Gene Expression Regulation, Hippo signaling, sense organs, YAP, Generic health relevance, Signal transduction, Transcription Factors, Signal Transduction, Biotechnology, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c77ed0bc1658205e4cb9f9a7e594dedTest
https://doi.org/10.1101/gad.274027.115Test -
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المؤلفون: Kun-Liang Guan, Jenna L. Jewell, Hai Xin Yuan, Ryan C. Russell, Zhen Wang, Fulong Li, Fa-Xing Yu
المصدر: Genes & development, vol 29, iss 22
مصطلحات موضوعية: NLK, 1.1 Normal biological development and functioning, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Medical and Health Sciences, mTORC2, 03 medical and health sciences, 0302 clinical medicine, Underpinning research, Osmotic Pressure, Genetics, cancer, Humans, Gene Knock-In Techniques, Phosphorylation, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, 030304 developmental biology, 0303 health sciences, Cell growth, Kinase, TOR Serine-Threonine Kinases, Psychology and Cognitive Sciences, HEK 293 cells, Signal Transducing, Adaptor Proteins, stress response, Regulatory-Associated Protein of mTOR, Biological Sciences, Raptor, Cell biology, Enzyme Activation, HEK293 Cells, Multiprotein Complexes, mTOR, biology.protein, Cancer research, Mitogen-Activated Protein Kinases, biological phenomena, cell phenomena, and immunity, Gene Deletion, 030217 neurology & neurosurgery, Research Paper, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f309a9310e80c56ac7c2ca7f3465548Test
https://doi.org/10.1101/gad.265116.115Test -
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المؤلفون: Yanping Xu, Yue Xiong, Meng-Xi Liu, Zhen Wang, Xu Feng, Xin Zhou, Qun-Ying Lei, Indrani Das, Tingting Li, Yi-Ping Sun, Kun-Liang Guan
المصدر: The Journal of biological chemistry, vol 289, iss 6
مصطلحات موضوعية: Nude, Lysine, Dehydrogenase, P300-CBP Transcription Factors, Medical and Health Sciences, Biochemistry, Mice, Neoplasms, p300-CBP Transcription Factors, Inbred BALB C, Glyceraldehyde 3-phosphate dehydrogenase, Cancer, Mice, Inbred BALB C, Tumor, biology, GAPDH, Lung Cancer, Glyceraldehyde-3-Phosphate Dehydrogenases, Acetylation, Biological Sciences, Neoplasm Proteins, Acetyltransferase, Glycolysis, Signal Transduction, Biochemistry & Molecular Biology, Mice, Nude, Cell Growth, Histone Deacetylases, Cell Line, Enzyme activator, stomatognathic system, Histone Deacetylase, Cell Line, Tumor, PCAF, Animals, Humans, Molecular Biology, Cell Proliferation, HDAC5, Cell Biology, Enzyme Activation, Metabolism, Glucose, HEK293 Cells, Tumorigenesis, Chemical Sciences, biology.protein, Histone deacetylase
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f252707ada7355679c72120d9916266dTest
https://doi.org/10.1074/jbc.m113.531640Test -
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المؤلفون: Audrey W. Hong, Steven W. Plouffe, Kun-Liang Guan
المصدر: Trends in molecular medicine, vol 21, iss 4
مصطلحات موضوعية: TAZ, Carcinogenesis, Apoptosis, medicine.disease_cause, Medical and Health Sciences, Receptors, G-Protein-Coupled, Hippo, Neoplasms, Cell polarity, Receptors, Drosophila Proteins, Homeostasis, Developmental, Tissue homeostasis, Mammals, Intracellular Signaling Peptides and Proteins, Gene Expression Regulation, Developmental, Nuclear Proteins, Organ Size, Biological Sciences, Cell biology, Gene Expression Regulation, Neoplastic, Drosophila melanogaster, Molecular Medicine, YAP, Signal transduction, Signal Transduction, animal structures, 1.1 Normal biological development and functioning, Immunology, Biology, Protein Serine-Threonine Kinases, Article, G-Protein-Coupled, Underpinning research, medicine, Genetics, Animals, Humans, cancer, Hippo Signaling Pathway, Molecular Biology, Transcription factor, Cell Proliferation, Hippo signaling pathway, Neoplastic, disease, Cell growth, fungi, YAP-Signaling Proteins, Actin cytoskeleton, body regions, Gene Expression Regulation, Trans-Activators, sense organs, Generic health relevance, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260566166e3e822e6dce8920ae5b72bdTest
https://escholarship.org/uc/item/8wn186v3Test -
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المؤلفون: Qian Yang, Ken Inoki, Eunjung Kim, Kun-Liang Guan
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 103(18)
مصطلحات موضوعية: Proto-Oncogene Proteins c-akt, Biology, Cell morphology, Tuberous Sclerosis Complex 1 Protein, Cell Line, Mice, Tuberous Sclerosis Complex 2 Protein, medicine, TOR complex, Animals, Drosophila Proteins, Humans, Small GTPase, Genes, Tumor Suppressor, Monomeric GTP-Binding Proteins, Mice, Knockout, Multidisciplinary, Cell growth, Ribosomal Protein S6 Kinases, Tumor Suppressor Proteins, HEK 293 cells, Neuropeptides, Biological Sciences, Phosphoproteins, Cell biology, medicine.anatomical_structure, Drosophila melanogaster, Multiprotein Complexes, biology.protein, RNA Interference, Ras Homolog Enriched in Brain Protein, TSC1, RHEB, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891142754492498b11cf5ff6c2a4b561Test
https://pubmed.ncbi.nlm.nih.gov/16627617Test -
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المؤلفون: Yi Sun, Mingjia Tan, Kun-Liang Guan, Yixin Wang
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 97(1)
مصطلحات موضوعية: Transcriptional Activation, TGF alpha, Pregnancy Proteins, Transfection, Transactivation, Genes, Reporter, Transforming Growth Factor beta, Tumor Cells, Cultured, Humans, Growth factor receptor inhibitor, Growth Substances, Promoter Regions, Genetic, Etoposide, Smad4 Protein, Glutathione Peroxidase, Multidisciplinary, Binding Sites, biology, Chemotactic Factors, Cell growth, S100 Proteins, Transforming growth factor beta, Biological Sciences, Molecular biology, DNA-Binding Proteins, Transforming growth factor, beta 3, biology.protein, Trans-Activators, Signal transduction, Tumor Suppressor Protein p53, Receptors, Transforming Growth Factor beta, Cell Division, Transforming growth factor, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2426b10f4db700cb705c3907c66cea88Test
https://pubmed.ncbi.nlm.nih.gov/10618379Test