المؤلفون: Garuti L, Roberti M, Bottegoni G.

المساهمون: Garuti, L, Roberti, M, Bottegoni, G.

مصطلحات موضوعية: ATP-competitive, benzimidazole, biological activity, kinase inhibition, multi-target inhibitor, SAR, selectivity, HETEROCYCLES

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000336248200005; volume:21; issue:20; firstpage:2284; lastpage:2298; numberofpages:15; journal:CURRENT MEDICINAL CHEMISTRY; http://hdl.handle.net/11576/2688441Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84900307958

الإتاحة: https://doi.org/10.2174/0929867321666140217105714Test
http://hdl.handle.net/11576/2688441Test

المؤلفون: Riccardo Rondanin, Marinella Roberti, Marcello Rossi, Silvia Marino, Valerio Bertolasi, Stefania Merighi, Daniele Simoni, Stefania Grimaudo, Daniela Pizzirani, Anna Siniscalchi, Pier Andrea Borea, Katia Varani, Manlio Tolomeo, Stefania Gessi, Francesco Paolo Invidiata, Riccardo Baruchello, Sabrina Cavallini, Clementina Bianchi

المساهمون: SIMONI D, ROSSI M, BERTOLASI V, ROBERTI M, PIZZIRANI D, RONDANIN R, BARUCHELLO R, INVIDIATA FP, TOLOMEO M, GRIMAUDO S, MERIGHI S, VARANI K, GESSI S, BOREA PA, MARINO S, CAVALLINI S, BIANCHI C, SINISCALCHI A, Simoni D., Rossi M., Bertolasi V., Roberti M., Pizzirani D., Rondanin R., Baruchello R., Invidiata F. P., Tolomeo M., Grimaudo S., Merighi S., Varani K., Gessi S., Borea P. A., Marino S., Cavallini S., Bianchi C., Siniscalchi A.

مصطلحات موضوعية: Stereochemistry, Dopamine, Dopamine Plasma Membrane Transport Proteins, Molecular Conformation, Nerve Tissue Proteins, In Vitro Techniques, Binding, Competitive, Dopamine Plasma Membrane Transport Protein, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine Uptake Inhibitors, Cocaine, triple reuptake, Drug Discovery, medicine, Animals, Structure–activity relationship, Dopamine transporter, Benztropine, Nerve Endings, Membrane Glycoproteins, biology, Putamen, Membrane Transport Proteins, Stereoisomerism, Tropane, Biological activity, Corpus Striatum, Rats, chemistry, biology.protein, Molecular Medicine, Tropanes, medicine.drug

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ebb8688abc561b14eb5208f3f5ff23Test
http://hdl.handle.net/10447/14975Test

المؤلفون: GARUTI, LAURA, ROBERTI, MARINELLA, BOTTEGONI, GIOVANNI

المساهمون: Garuti L, Roberti M, Bottegoni G

مصطلحات موضوعية: ATP-competitive, biological activity, heterocycle, inhibition, irreversible inhibitor, kinase, multi-target, SAR, antitumor

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25511779; info:eu-repo/semantics/altIdentifier/wos/WOS:000349388600004; volume:22; issue:6; firstpage:695; lastpage:712; numberofpages:17; journal:CURRENT MEDICINAL CHEMISTRY; http://hdl.handle.net/11585/418766Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84931266088

الإتاحة: https://doi.org/10.2174/0929867321666141216125528Test
http://hdl.handle.net/11585/418766Test

المؤلفون: Stefania Grimaudo, Rosaria Maria Pipitone, Maurizio Recanatini, Manlio Tolomeo, Marinella Roberti, Antonietta Di Cristina, Daniela Pizzirani

المساهمون: Pizzirani D., Roberti M., Grimaudo S., Di Cristina A., Pipitone R.M., Tolomeo M., Recanatini M.

المصدر: Journal of Medicinal Chemistry. 52:6936-6940

مصطلحات موضوعية: Antineoplastic Agents, Apoptosis, HL-60 Cells, Chemical synthesis, Structure-Activity Relationship, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Terphenyl Compounds, Drug Discovery, medicine, Humans, Spiro Compounds, Chemistry, Biphenyl Compounds, Cell Differentiation, Biological activity, Ketones, medicine.disease, In vitro, Leukemia, Proto-Oncogene Proteins c-bcl-2, Biochemistry, Cell culture, Molecular Medicine, K562 Cells, Intracellular

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cc5dd797fcf909b1d3759643286e54Test
https://doi.org/10.1021/jm900907sTest

المؤلفون: Marinella Roberti, Giovanni Bottegoni, Laura Garuti

المساهمون: Garuti L, Roberti M, Bottegoni G, DIP. DI SCIENZE FARMACEUTICHE, DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE, Facolta' di FARMACIA, AREA MIN. 03 - Scienze chimiche, Da definire

المصدر: Current medicinal chemistry. 22(6)

مصطلحات موضوعية: Indoles, kinase, Pyridines, irreversible inhibitors, biological activity, Computational biology, SAR, Biology, ATP-competitive, heterocycles, inhibition, multi-target, antitumor, Biochemistry, Multikinase inhibitor, Drug Discovery, Screening method, Animals, Humans, Protein Kinase Inhibitors, Pharmacology, Kinase, irreversible inhibitor, Organic Chemistry, Biological activity, Combinatorial chemistry, Structural homology, Pyrimidines, Molecular Medicine, Pharmacophore, Protein Kinases, heterocycle, Cysteine

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d0c208695a04914b8e9de2bc3be52fTest
https://pubmed.ncbi.nlm.nih.gov/25511779Test

المؤلفون: Marinella Roberti, Laura Garuti, Giovanni Bottegoni

المساهمون: Garuti L, Roberti M, Bottegoni G.

المصدر: Current medicinal chemistry. 21(20)

مصطلحات موضوعية: Models, Molecular, Benzimidazole, Stereochemistry, biological activity, Biology, ATP-competitive, benzimidazole, kinase inhibition, multi-target inhibitor, SAR, selectivity, HETEROCYCLES, Biochemistry, Cell Line, chemistry.chemical_compound, Structure-Activity Relationship, Protein structure, Biological property, Drug Discovery, Structure–activity relationship, Humans, Protein Kinase Inhibitors, Pharmacology, chemistry.chemical_classification, Kinase, Organic Chemistry, Biological activity, Protein Structure, Tertiary, Enzyme, chemistry, Cell culture, Molecular Medicine, Benzimidazoles

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eac0794705d576fb8a1f514b2b65b9dTest
https://pubmed.ncbi.nlm.nih.gov/24533813Test