المؤلفون: Lucia Parlati, Catherine Postic, Marion Régnier, Hervé Guillou

المساهمون: LESUR, Hélène, Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance - - HepAdialogue2017 - ANR-17-CE14-0015 - AAPG2017 - VALID, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Catholique de Louvain = Catholic University of Louvain (UCL), ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Toxicologie Intégrative & Métabolisme (ToxAlim-TIM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Lucia Parlati and Catherine Postic received funding from the French association for the study of the liver (AFEF). Catherine Postic and Herve Guillou received funding from the Agence Nationale de la Recherche (ANR-17-CE14-0015Hepadialogue)., ANR-17-CE14-0015,HepAdialogue,Impact du métabolisme des acides gras des tissus adipeux et du foie sur l'insulinorésistance(2017), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)

المصدر: JHEP Reports
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (6), pp.100346. ⟨10.1016/j.jhepr.2021.100346⟩

مصطلحات موضوعية: HFD, high-fat diet, SREBP-1c, [SDV]Life Sciences [q-bio], Disease, Review, ACC, acetyl-CoA carboxylase, ASK1, apoptosis signal-regulating kinase 1, Chronic liver disease, Bioinformatics, ChREBP, carbohydrate responsive element–binding protein, PPARα, NEFA, TNF-α, tumour necrosis factor-α, 0302 clinical medicine, Fibrosis, Immunology and Allergy, Medicine, IL-, interleukin, VLDL, very low-density lipoprotein, 0303 health sciences, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, NEFA, non-esterified fatty acid, Fatty liver, Gastroenterology, NASH, lipotoxicity, FAS, fatty acid synthase, animal models, 3. Good health, [SDV] Life Sciences [q-bio], PY, persons/years, Lipotoxicity, FXR, Saturated fatty acid, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, LXR, CAP, controlled attenuation parameter, HSL, hormone-sensitive lipase, HSC, hepatic stellate cells, GGT, gamma glutamyltransferase, NAFLD, non-alcoholic fatty liver disease, ChREBP, NASH, non-alcoholic steatohepatitis, SFA, saturated fatty acid, TCA, tricarboxylic acid, Phf2, histone demethylase plant homeodomain finger 2, digestive system, 03 medical and health sciences, glucotoxicity, FXR, farnesoid X receptor, NAFLD, FFA, free fatty acid, Internal Medicine, RCT, randomised controlled trial, Liver X receptor, PPARa, 030304 developmental biology, FGF21, fibroblast growth factor-21, MCD, methionine- and choline-deficient, HVPG, hepatic venous pressure gradient, Hepatology, business.industry, PUFAs, polyunsaturated fatty acids, nutritional and metabolic diseases, TLR4, Toll-like receptor 4, SCD1, stearoyl-CoA desaturase-1, medicine.disease, digestive system diseases, PPARα, peroxisome proliferator-activated receptor-α, SREBP-1c, sterol regulatory element–binding protein-1c, Steatosis, LXR, liver X receptor, business, HCC, hepatocellular carcinoma, MUFA, monounsaturated fatty acids, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba31673956635c337dc60791ff712432Test
https://pubmed.ncbi.nlm.nih.gov/34667947Test

المؤلفون: Nikolaos Perakakis, Konstantinos Stefanakis, Christos S. Mantzoros

المصدر: Metabolism

مصطلحات موضوعية: Proteomics, HCC, Hepatocellular carcinoma, Cirrhosis, SWE, Shear wave elastography, Endocrinology, Diabetes and Metabolism, TM6SF2, Transmembrane 6 superfamily member 2, Disease, CK-18, Cytokeratin-18, GCKR, Glucokinase regulatory protein, HDACis, HDAC inhibitors, transcriptomics, HSI, Hepatic Steatosis index, 0302 clinical medicine, Endocrinology, DAG, Diacylglycerol, EPA, Eicosapentanoic acid, MRI-PDFF, Magnetic resonance imaging derived proton density fat fraction, PE, Phosphatidylethanolamine, lncRNA, Long noncoding RNA, CAP, Controlled attenuation parameter, IgG, Immunoglobulin G, NASH, NAFLD, Non-alcoholic fatty liver disease, Genomics, TGF, Transforming growth factor, DHA, Docosahexaenoic acid, GRS, Genetic risk score, CRP, C-reactive protein, DHEA, Dehydroepiandrosterone, DNMTis, DNA methylation inhibitors, medicine.medical_specialty, PDGF, Platelet-derived growth factor, NASH, non-alcoholic steatohepatitis, DZNep, 3-deazaneplanocin A, tRNA, Transport RNA, PLA2, Phospholipase A2, digestive system, Article, TG, Triglyceride, 03 medical and health sciences, IL-32, Interleukin 32, AUROC, Area under the receiver operator characteristics, Humans, Metabolomics, MS, Mass Spectrometry, SPM, Specialized pro-resolving mediator, nutritional and metabolic diseases, TOF, Time-of-flight, medicine.disease, Omics, AST, Aspartate transaminase, PNPLA3, Patatin-like phospholipase domain-containing-3, digestive system diseases, NAFL, Non-alcoholic fatty liver, 030104 developmental biology, FXR, Farnesoid X receptor, PTPRE, protein-tyrosine phosphatase epsilon, Steatohepatitis, IGF, Insulin growth factor, ROS, Reactive oxygen species, ACC, Acetyl-coA carboxylase, Liver Cirrhosis, 0301 basic medicine, F#, Fibrosis (score), LPE, Lysophosphatidylethanolamine, LSM, Liver stiffness measurement, IL-32, Interleukin-32, VCTE, Vibration-controlled transient elastography, Bioinformatics, glycomics, HAT, Histone acetyltransferase, Non-alcoholic Fatty Liver Disease, APRI, Aspartate aminotransferase to platelet ratio index, steatosis, FADS, Fatty acid desaturase, circRNA, Circular RNA, NFS, NAFLD fibrosis score, PUFA, Polyunsaturated fatty acid, SNP, Single nucleotide polymorphism, NAS, NAFLD activity score, medicine.diagnostic_test, Fatty liver, AA, Arachidonic acid, IL-10, Interleukin-10, SFA, Saturated fatty acids, Liver biopsy, LPC, Lysophosphatidylcholine, FIB-4, Fibrosis-4 score, IGFBP, Insulin growth factor binding protein, ApoE, Apolipoprotein E, GGT, Gamma-glutamyltransferase, ChREBP, Carbohydrate, responsive element-binding protein, MUFA, Monounsaturated fatty acid, PC, Phosphatidylcholine, 030209 endocrinology & metabolism, PPAR, Peroxisome proliferator-activated receptor, HFD, High fat diet, Internal medicine, medicine, Animals, MetS, Metabolic syndrome, IL-6, Interleukin-6, MRE, magnetic resonance elastography, SIRT, Sirtuin, SELDI, Surface-enhanced laser desorption/ionization, BMI, Body mas index, business.industry, HDAC, Histone deacetylase, WC, Waist circumference, ALT, Alanine aminotransferase, CHI3L1, Chitinase 3 Like 1, FFA, Free fatty acids, GWAS, Genome - wide association studies, epigenomics, HSD17B13, 17-b retinol dehydrogenase 13, miR, Micro RNA, lipidomics, 1H-MRS, Magnetic resonance imaging and proton spectroscopy, MBOAT7, Membrane bound O-acyltransferase domain-containing 7, Steatosis, business, OR, Odds ratio, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bb96bcd7fb056ebf01eec2214ad114Test
https://doi.org/10.1016/j.metabol.2020.154320Test

المؤلفون: Sonia García-Calzón, Karl Bacos, Cajsa Davegårdh, Charlotte Ling

المصدر: Molecular Metabolism
Molecular Metabolism, Vol 14, Iss, Pp 12-25 (2018)

مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, endocrine system diseases, BMI, body mass index, FH, family history, OXPHOS, oxidative phosphorylation, NBW, normal birth weight, Genome-wide association study, HDAC, histone deacetylase, Disease, Type 2 diabetes, Bioinformatics, WGBS, whole-genome bisulfite sequencing, CIT, causal inference test, 0302 clinical medicine, Special Section on Epigenetics (2018), PUFA, polyunsaturated fatty acids, DNA methylation, ncRNA, non-coding RNA, DMR, differentially methylated region, SNP, single nucleotide polymorphism, MZ, monozygotic, 3. Good health, Adipose Tissue, Liver, eQTL, expression quantitative trait loci, Medical genetics, Epigenetics, nt, nucleotide, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, HOMA-IR, homeostatic model assessment for insulin resistance, NASH, non-alcoholic steatohepatitis, HDL, high-density lipoprotein, 030209 endocrinology & metabolism, T2D, type 2 diabetes, Biology, EWAS, epigenome-wide association study, LBW, low birth weight, 03 medical and health sciences, Islets of Langerhans, Insulin resistance, medicine, OGTT, oral glucose-tolerance test, Humans, lcsh:RC31-1245, Muscle, Skeletal, GWAS, genome-wide association study, Molecular Biology, nutritional and metabolic diseases, Cell Biology, Epigenome, medicine.disease, mQTL, methylation quantitative trait loci, 030104 developmental biology, Diabetes Mellitus, Type 2, DNMT, DNA methyltransferase, SFA, saturated fatty acids, TSS, transcription start site, MeDIP, methylated DNA immunoprecipitation, HbA1c, glycated hemoglobin A1c

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb9a91dde2ed703af4dea93e95946b7Test