Low-Iodine Diet of 4 Days Is Sufficient Preparation for I-131 Therapy in Differentiated Thyroid Cancer Patients
| العنوان: | Low-Iodine Diet of 4 Days Is Sufficient Preparation for I-131 Therapy in Differentiated Thyroid Cancer Patients |
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| المؤلفون: | Judith A P Bons, Adrienne H. Brouwers, Mirthe H Links, Linda G Swart-Busscher, Anneke C. Muller Kobold, Bernadette L Dekker, Thera P. Links, Marleen Kars, Anouk N A van der Horst-Schrivers |
| المساهمون: | Interne Geneeskunde, MUMC+: MA Endocrinologie (9), MUMC+: DA CDL Algemeen (9), RS: NUTRIM - R3 - Respiratory & Age-related Health, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Damage and Repair in Cancer Development and Cancer Treatment (DARE) |
| المصدر: | The Journal of Clinical Endocrinology and Metabolism Journal of Clinical Endocrinology & Metabolism, 107(2), E604-E611. Oxford University Press Journal of Clinical Endocrinology & Metabolism, 107(2), E604-E611. ENDOCRINE SOC |
| بيانات النشر: | Oxford University Press, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Male, Calorie, SYMPORTER, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Urine, REEVALUATION, Biochemistry, Gastroenterology, ABLATION THERAPY, Iodine Radioisotopes, Endocrinology, low-iodine diet, ASSOCIATION GUIDELINES, Prospective Studies, Prospective cohort study, Thyroid cancer, individual perceptions, urinary iodine excretion, OUTPATIENT PREPARATION, Radioiodine therapy, Middle Aged, radioactive iodine therapy, Diet Records, iodine intake, EXPERIENCES, Female, AcademicSubjects/MED00250, Iodine, Adult, medicine.medical_specialty, nutrition diary, chemistry.chemical_element, Nutritional Status, Context (language use), Excretion, SEVERE HYPONATREMIA, Internal medicine, medicine, MANAGEMENT, Humans, Thyroid Neoplasms, Online Only Articles, Clinical Research Articles, Aged, business.industry, Biochemistry (medical), medicine.disease, Diet, Trace Elements, chemistry, business |
| الوصف: | Context No consensus exists about the optimal duration of the low-iodine diet (LID) in the preparation of 131I therapy in differentiated thyroid cancer (DTC) patients. Objective This work aimed to investigate if a LID of 4 days is enough to achieve adequate iodine depletion in preparation for 131I therapy. In addition, the nutritional status of the LID was evaluated. Methods In this prospective study, 65 DTC patients treated at 2 university medical centers were included between 2018 and 2021. The patients collected 24-hour urine on days 4 and 7 of the LID and kept a food diary before and during the LID. The primary outcome was the difference between the 24-hour urinary iodine excretion (UIE) on both days. Results The median 24-hour UIE on days 4 and 7 of the LID were not significantly different (36.1 mcg [interquartile range, 25.4-51.2 mcg] and 36.5 mcg [interquartile range, 23.9-47.7 mcg], respectively, P = .43). On day 4 of the LID, 72.1% of the DTC patients were adequately prepared (24-hour UIE Conclusion The 24-hour UIE on day 4 of the LID did not differ from day 7, and therefore shortening the LID from 7 to 4 days seems justified to prepare DTC patients for 131I therapy in areas with sufficient iodine intake and may be beneficial to maintain a sufficient nutritional intake during DTC treatment. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1945-7197 0021-972X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b54d07dc54c7b21d36a7b33ca1396aaTest https://cris.maastrichtuniversity.nl/en/publications/b8f538fa-bf84-4e2f-b21b-501bcbaab0f6Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0b54d07dc54c7b21d36a7b33ca1396aa |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19457197 0021972X |
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