المؤلفون: Bin Shen, Esther J.M. Kooijman, Albert D. Windhorst, Frederick T. Chin, Madina Nezam, Samantha T. Reyes, Berend van der Wildt

المساهمون: Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging

المصدر: Bioorganic and Medicinal Chemistry, 42:116245. Elsevier Limited
van der Wildt, B, Nezam, M, Kooijman, E J M, Reyes, S T, Shen, B, Windhorst, A D & Chin, F T 2021, ' Evaluation of carbon-11 labeled 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide as PET tracer for imaging of CSF-1R expression in the brain ', Bioorganic and Medicinal Chemistry, vol. 42, 116245 . https://doi.org/10.1016/j.bmc.2021.116245Test

مصطلحات موضوعية: Tariquidar, Clinical Biochemistry, Pharmaceutical Science, Receptor, Macrophage Colony-Stimulating Factor, Pharmacology, 01 natural sciences, Biochemistry, Colony stimulating factor 1 receptor, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Carbon Radioisotopes, Molecular Biology, IC50, Trifluoromethyl, Nicotinamide, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Radiosynthesis, Brain, In vitro, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, Positron-Emission Tomography, Molecular Medicine, Ex vivo, medicine.drug

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6407f64f503e7d9f00f9d31aa43890Test
https://pubmed.ncbi.nlm.nih.gov/34119698Test

المؤلفون: Neil Vasdev, Karl T. Schmidt, Ashley C Knight, Shil Patel, Lee Josephson, Tong Zi, Steven H. Liang, Cassis Varlow

المصدر: ACS Chem Neurosci

مصطلحات موضوعية: 0303 health sciences, biology, Physiology, Chemistry, Cognitive Neuroscience, Cell Biology, General Medicine, Pharmacology, Ligand (biochemistry), Biochemistry, In vitro, Article, Colony stimulating factor 1 receptor, 03 medical and health sciences, 0302 clinical medicine, In vivo, Radioligand, Translocator protein, biology.protein, Receptor, 030217 neurology & neurosurgery, Neuroinflammation, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec6bdd7562b53907a59cbd28f8820c6Test
https://europepmc.org/articles/PMC9350903Test/

المؤلفون: Jianlin Cui, Saijun Fan, Kexin Wang, Yue Shang, Yuhao Li, Yajia Cheng, Peipei Cao, Jing Yu, Huiling Meng

المصدر: Biochemical and biophysical research communications. 551

مصطلحات موضوعية: biology, Cas9, Mutant, Biophysics, Receptor, Macrophage Colony-Stimulating Factor, Cell Biology, biology.organism_classification, Biochemistry, Receptor tyrosine kinase, Cell biology, Colony stimulating factor 1 receptor, Gene Knockout Techniques, Immune system, Larva, Mutation, biology.protein, CRISPR, Animals, CRISPR-Cas Systems, Receptor, Molecular Biology, Zebrafish, Locomotion

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c383f95b889e156463e29edd937f449Test
https://pubmed.ncbi.nlm.nih.gov/33725575Test

المؤلفون: Xiaoyun Zhou (119506), Bin Ji (334060), Chie Seki (3762124), Yuji Nagai (303799), Takafumi Minamimoto (299783), Masayuki Fujinaga (136798), Ming-Rong Zhang (136828), Takashi Saito (243551), Takaomi C Saido (10449970), Tetsuya Suhara (217626), Yasuyuki Kimura (297748), Makoto Higuchi (217616)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Emergency Medicine, Endocrinology, Radiology and Organ Imaging, Neurology and Neuromuscular Diseases, Biological Sciences not elsewhere classified, colony-stimulating factor 1 receptor, positron emission tomography, PET, neuroinflammation, 11C-GW2580, microglia

العلاقة: https://figshare.com/articles/journal_contribution/sj-pdfTest-1-jcb-10_1177_0271678X211004146_-_Supplemental_material_for_PET_imaging_of_colony-stimulating_factor_1_receptor_A_head-to-head_comparison_of_a_novel_radioligand_sup_11_sup_C-GW2580_and_sup_11_sup_C-CPPC_in_mouse_models_of_acute_and_c/14307667

الإتاحة: https://doi.org/10.25384/sage.14307667.v1Test

المؤلفون: Masashi Kakae, Hisashi Shirakawa, Misa Morishima, Shuji Kaneko, Shota Tobori, Kazuki Nagayasu

المصدر: Biochemical and Biophysical Research Communications. 514:1040-1044

مصطلحات موضوعية: Male, 0301 basic medicine, Central nervous system, Biophysics, Biochemistry, Neuroprotection, Proinflammatory cytokine, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Cognitive Dysfunction, Interleukin 6, Molecular Biology, White matter injury, Microglia, biology, Colony-stimulating factor 1, business.industry, Chronic cerebral hypoperfusion, Neurotoxicity, Cell Biology, medicine.disease, White Matter, Mice, Inbred C57BL, Cerebrovascular Disorders, Disease Models, Animal, Cognitive impairment, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Chronic Disease, Immunology, biology.protein, Cytokines, Tumor necrosis factor alpha, business, Homeostasis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c42098459829c66bc56099e0f42b2aTest
https://doi.org/10.1016/j.bbrc.2019.05.055Test

المؤلفون: Yasunori Hase, Kazutaka Ikegashira, Hiromasa Hashimoto, Takayuki Yamasaki, Iichiro Kawahara, Taku Ikenogami, Yoshihisa Koga, Koji Inagaki, Naoki Miyagawa, Takahiro Oka

المصدر: Bioorganic & Medicinal Chemistry Letters. 29:873-877

مصطلحات موضوعية: Models, Molecular, Cellular activity, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Arthritis, Pharmacology, 01 natural sciences, Biochemistry, Colony stimulating factor 1 receptor, Mice, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, medicine, Animals, Humans, Receptor, Protein Kinase Inhibitors, Molecular Biology, Molecular Structure, 010405 organic chemistry, Chemistry, Kinase, Organic Chemistry, medicine.disease, Arthritis, Experimental, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Gene Expression Regulation, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Azetidines, Molecular Medicine, Collagen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f442336db72895a98e9e75673b64cf0Test
https://doi.org/10.1016/j.bmcl.2019.02.006Test

المؤلفون: Rajavashisth, Tripathi B., Eng, Ronald, Shadduck, Richard K., Waheed, Abdul, Ben-Avram, Chad M., Shively, John E., Lusis, Aldons J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1987 Mar 01. 84(5), 1157-1161.

الوصول الحر: https://www.jstor.org/stable/29154Test

المؤلفون: Roussel, Martine F., Downing, James R., Ashmun, Richard A., Rettenmier, Carl W., Sherr, Charles J.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1988 Aug . 85(16), 5903-5907.

الوصول الحر: https://www.jstor.org/stable/32267Test

المؤلفون: Jian Zou, Qiuju Xun, Zhang Zhang, Zhen Wang, Zhengchao Tu, Yingqiang Liu, Linjiang Tong, Hua Xie, Ke Ding, Xiaoyun Lu, Yong Xu, Jinfeng Luo, Minhao Huang

المصدر: Journal of Medicinal Chemistry. 61:2353-2371

مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Biological Availability, Antineoplastic Agents, Rats, Sprague-Dawley, Colony stimulating factor 1 receptor, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, ErbB Receptors, 0302 clinical medicine, Cell Movement, Drug Discovery, Animals, Structure–activity relationship, Epidermal growth factor receptor, Receptor, Protein Kinase Inhibitors, IC50, Molecular Structure, biology, Kinase, Macrophages, Rats, Pyrimidines, RAW 264.7 Cells, 030104 developmental biology, Neutrophil Infiltration, chemistry, Biochemistry, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Drug Design, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Lead compound

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a80fbb39b1b47a21f056bddbd73d071Test
https://doi.org/10.1021/acs.jmedchem.7b01612Test

المؤلفون: Jessica Bauer, Yasna Jain, Taher A. Saif, Barbara Jung, Bashar Emon

المصدر: Computational and Structural Biotechnology Journal, Vol 16, Iss, Pp 279-287 (2018)
Computational and Structural Biotechnology Journal

مصطلحات موضوعية: 0301 basic medicine, EMT, Epithelial to mesenchymal transition, VEGF, Vascular endothelial growth factor, TACs, Tumor-associated collagen signatures, IGFs, Insulin-like growth factors, IL-13, Interleukin-13, Review Article, LOX, Lysyl Oxidase, Biochemistry, Metastasis, SDF-1/CXCL12, Stromal cell-derived factor 1/C-X-C motif chemokine 12, Extracellular matrix, α-SMA, α-Smooth muscle actin, 0302 clinical medicine, Structural Biology, TNF-α, Tumor necrosis factor-α, HGF/SF, Hepatocyte growth factor/Scatter factor, Cancer, CSF-1, Colony stimulating factor 1, MMPs, Matrix metalloproteinases, 3. Good health, Computer Science Applications, Tumor biophysics, EGF, Epidermal growth factor, 030220 oncology & carcinogenesis, CAF, Cancer associated fibroblast, ECM stiffness, Growth factors, Biotechnology, Stromal cell, KGF, Keratinocyte growth factor, also FGF7, lcsh:Biotechnology, CYR61/CCN1, Cysteine-rich angiogenic inducer 61/CCN family member 1, Biophysics, Cancer metastasis, NO, Nitric oxide, 03 medical and health sciences, ECM, Extracellular matrix, IL-33, Interleukin-33, Stroma, lcsh:TP248.13-248.65, TGFβ, Transforming growth factor β, Genetics, medicine, IL-6, Interleukin-6, Tumor microenvironment, business.industry, technology, industry, and agriculture, medicine.disease, Activin/TGFβ, 030104 developmental biology, ADAMs, Adamalysins, CTGF, Connective tissue growth factor, Cancer cell, Cancer research, ANGPT2, Angiopoietin 2, business, FGF, Fibroblast growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f502b279b62334028d536320270ae9Test
https://doi.org/10.1016/j.csbj.2018.07.003Test