المؤلفون: Kang Wang, Yuan Yang, Jian-Hua Zhou, Lin-Xia Deng, Jing Yang, Luo-Wen Zhou

المصدر: Current Medical Science. 41:1029-1036

مصطلحات موضوعية: Adult, Male, Models, Molecular, Silent mutation, China, Heterozygote, TRPP Cation Channels, Protein Conformation, RNA Splicing, Autosomal dominant polycystic kidney disease, Gene mutation, Biology, urologic and male genital diseases, Biochemistry, Paternal Age, Solitary Kidney, symbols.namesake, Exon, Exome Sequencing, Genetics, medicine, Humans, Child, Silent Mutation, Sanger sequencing, PKD1, urogenital system, Middle Aged, Polycystic Kidney, Autosomal Dominant, medicine.disease, female genital diseases and pregnancy complications, Pedigree, Mutation (genetic algorithm), symbols, Female, Synonymous substitution

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc3756c2fad2aceb3834949e4319df0Test
https://doi.org/10.1007/s11596-021-2436-9Test

المؤلفون: Xingquan Zhou, Yumei Lu, Lirong Zhang, Xu Zhu, Meijuan Geng, Yi Lu, Hui Xiong

المصدر: Biochemical and Biophysical Research Communications. 561:73-79

مصطلحات موضوعية: 0301 basic medicine, TRPP Cation Channels, Arginine, Eukaryotic Initiation Factor-2, Biophysics, Endoplasmic Reticulum, urologic and male genital diseases, Biochemistry, Serine, Mice, eIF-2 Kinase, 03 medical and health sciences, 0302 clinical medicine, GTP-Binding Proteins, Databases, Genetic, Animals, Humans, Amino Acids, Molecular Biology, Cells, Cultured, Amino acid synthesis, chemistry.chemical_classification, urogenital system, Endoplasmic reticulum, ATF4, Cell Biology, Polycystic Kidney, Autosomal Dominant, Activating Transcription Factor 4, female genital diseases and pregnancy complications, Amino acid, Cell biology, Disease Models, Animal, 030104 developmental biology, Gene Expression Regulation, chemistry, 030220 oncology & carcinogenesis, Unfolded protein response, Signal Transduction, Cysteine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5c4e33fe7bf7a6a782e521a63a9364Test
https://doi.org/10.1016/j.bbrc.2021.05.012Test

المؤلفون: Shin-Ichi Mae, Tatsuya Shimizu, Keisuke Okita, Toshikazu Araoka, Kenji Osafune, Akitsu Hotta, Kunihiro Yamagata

المصدر: Biochemical and Biophysical Research Communications. 529:1186-1194

مصطلحات موضوعية: 0301 basic medicine, Disease specific, TRPP Cation Channels, Induced Pluripotent Stem Cells, Drug Evaluation, Preclinical, Biophysics, Autosomal dominant polycystic kidney disease, Disease, Kidney, urologic and male genital diseases, Models, Biological, Biochemistry, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Organoid, Humans, Medicine, Amino Acid Sequence, Induced pluripotent stem cell, Molecular Biology, Base Sequence, PKD1, urogenital system, business.industry, Colforsin, Cell Differentiation, Cell Biology, Polycystic Kidney, Autosomal Dominant, medicine.disease, female genital diseases and pregnancy complications, Organoids, Phenotype, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Mutation, Cancer research, business, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb15ba7ce2bf3317e6dbf3a2988532Test
https://doi.org/10.1016/j.bbrc.2020.06.141Test

المؤلفون: Julie A. Jonassen, Gregory J. Pazour, Roger J. Davis, Kenley Preval, Abigail O. Smith

المصدر: PLoS Genetics
PLoS Genetics, Vol 17, Iss 12, p e1009711 (2021)

مصطلحات موضوعية: Cancer Research, Cell signaling, Physiology, medicine.medical_treatment, QH426-470, Signal transduction, urologic and male genital diseases, Kidney, Biochemistry, Epithelium, Medical Conditions, Animal Cells, Polycystic kidney disease, Medicine and Health Sciences, Post-Translational Modification, Phosphorylation, Genetics (clinical), Cystic kidney, c-jun, Signaling cascades, Animal Models, Polycystic Kidney, Autosomal Dominant, c-Jun N-terminal kinase signaling cascade, Experimental Organism Systems, Physiological Parameters, Genetic Diseases, Anatomy, Cellular Types, Research Article, Cell biology, TRPP Cation Channels, MAP Kinase Signaling System, Autosomal dominant polycystic kidney disease, Mouse Models, Research and Analysis Methods, End stage renal disease, Cystic kidney disease, Model Organisms, Polycystic Kidney Disease, Weight Loss, medicine, Genetics, Humans, Mitogen-Activated Protein Kinase 9, Mitogen-Activated Protein Kinase 8, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Dialysis, Cell Proliferation, Clinical Genetics, PKD1, business.industry, urogenital system, Body Weight, Autosomal Dominant Diseases, JNK Mitogen-Activated Protein Kinases, Biology and Life Sciences, Proteins, Kidneys, Epithelial Cells, Renal System, medicine.disease, Fibrosis, Biological Tissue, Mutation, Cancer research, Animal Studies, business, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b84f3446b6baa3eda5738e929eeae6Test
http://europepmc.org/articles/PMC8746764Test

المؤلفون: Peng-fei Tian, Meng-meng Sun, Xian-yu Hu, Juan Du, Wei He

المصدر: Biochimie. 201

مصطلحات موضوعية: TRPP Cation Channels, Epidermal Growth Factor, TRPV Cation Channels, Calcium, Ryanodine Receptor Calcium Release Channel, General Medicine, Biochemistry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719de2d63c528ab54ec496b0d41a70abTest
https://pubmed.ncbi.nlm.nih.gov/35760123Test

المؤلفون: M. Pema, L. Drusian, M. Chiaravalli, M. Castelli, Q. Yao, S. Ricciardi, S. Somlo, F. Qian, A. Boletta, S. Biffo

المساهمون: M. Pema, L. Drusian, M. Chiaravalli, M. Castelli, Q. Yao, S. Ricciardi, S. Somlo, F. Qian, S. Biffo, A. Boletta

مصطلحات موضوعية: animal, cilia, cyst, down-regulation, gene expression regulation, gene silencing, mice, multiprotein complexe, polycystic kidney disease, sirolimu, TOR serine-threonine kinase, TRPP cation channel, tuberous sclerosi, up-regulation, biochemistry, genetics and molecular biology (all), chemistry (all), physics and astronomy (all), Settore BIO/06 - Anatomia Comparata e Citologia

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26931735; info:eu-repo/semantics/altIdentifier/wos/WOS:000371709000001; volume:7; firstpage:1; lastpage:11; numberofpages:11; journal:NATURE COMMUNICATIONS; http://hdl.handle.net/2434/492807Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84960193038

الإتاحة: https://doi.org/10.1038/ncomms10786Test
http://hdl.handle.net/2434/492807Test

المؤلفون: Zhen Wang, Chaofeng Hu, Liping Sun, Xinzhou Zhang

المصدر: IUBMB Life. 72:1340-1348

مصطلحات موضوعية: 0301 basic medicine, TRPP Cation Channels, Clinical Biochemistry, Autosomal dominant polycystic kidney disease, Regulator, Biology, Fibrinogen, Biochemistry, Transforming Growth Factor beta1, Mice, 03 medical and health sciences, 0302 clinical medicine, Fibrosis, Genetics, medicine, Polycystic kidney disease, Animals, Smad3 Protein, Molecular Biology, Mice, Knockout, Kidney, Cell Biology, Polycystic Kidney, Autosomal Dominant, medicine.disease, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, 030220 oncology & carcinogenesis, Cancer research, Signal transduction, medicine.drug, Transforming growth factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cabbba3d5da696c24c0a039a57f173Test
https://doi.org/10.1002/iub.2255Test

المؤلفون: Desheng Liang, Lanlan Zeng, Nana Liang, Lingqian Wu, Xuanyu Jiang, Zhuo Li

المصدر: Clinica Chimica Acta. 501:207-215

مصطلحات موضوعية: Adult, Cytoplasmic Dyneins, Male, 0301 basic medicine, China, TRPP Cation Channels, DNA Mutational Analysis, Clinical Biochemistry, Autosomal dominant polycystic kidney disease, Receptors, Cell Surface, Compound heterozygosity, medicine.disease_cause, Biochemistry, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Nephronophthisis, medicine, Humans, Missense mutation, Renal Insufficiency, Genetics, Mutation, PKD1, urogenital system, business.industry, Biochemistry (medical), High-Throughput Nucleotide Sequencing, Infant, Membrane Proteins, General Medicine, Kidney Diseases, Cystic, Middle Aged, medicine.disease, Ciliopathy, Phenotype, 030104 developmental biology, Child, Preschool, 030220 oncology & carcinogenesis, Female, Kidney disorder, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e5775af157a06d906297fec6346918Test
https://doi.org/10.1016/j.cca.2019.10.040Test

المؤلفون: Meike U. Rohrbach, Francisco J. Arjona, Eric H. J. Verschuren, René J. M. Bindels, Juan Pablo Rigalli, Charlotte Castenmiller, Dorien J.M. Peters, Joost G. J. Hoenderop

المصدر: The Faseb Journal, 34, 5, pp. 6382-6398
The Faseb Journal, 34, 6382-6398
FASEB Journal, 34(5), 6382-6398. WILEY

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, TRPP Cation Channels, fluid shear stress, Nerve Tissue Proteins, urologic and male genital diseases, Biochemistry, Connexins, Mice, 03 medical and health sciences, Adenosine Triphosphate, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Genetics, medicine, Polycystic kidney disease, Animals, Humans, Distal convoluted tubule, Molecular Biology, Zebrafish, Mice, Knockout, Polycystic Kidney Diseases, Kidney, PKD1, Mechanosensation, Cysts, urogenital system, Chemistry, pannexin-1, Purinergic signalling, Pannexin, medicine.disease, female genital diseases and pregnancy complications, Cell biology, Mice, Inbred C57BL, ATP, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], 030104 developmental biology, medicine.anatomical_structure, polycystin-1, Knockout mouse, Calcium, Stress, Mechanical, 030217 neurology & neurosurgery, purinergic signaling, Biotechnology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7194eec63145dfd9155a9746e361f9Test
https://hdl.handle.net/2066/219079Test

المؤلفون: Wendy A. Lea, M. Cristine Charlesworth, Marie C. Hogan, Lesya Zelenchuk, Kenneth L. Johnson, Stephen C. Parnell, Benjamin J. Madden, Madhulika Sharma, Christopher J. Ward, Kerri McGreal, Daniel J. McCormick

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

مصطلحات موضوعية: Proteomics, 0301 basic medicine, Glycosylation, TRPP Cation Channels, Fibrocystin, lcsh:Medicine, Receptors, Cell Surface, Exosomes, Cleavage (embryo), Biochemistry, Exosome, Article, 03 medical and health sciences, 0302 clinical medicine, Humans, Amino Acid Sequence, lcsh:Science, Peptide sequence, Multidisciplinary, biology, Chemistry, lcsh:R, Polycystin complex, Polycystic Kidney, Autosomal Dominant, Proprotein convertase, Transmembrane protein, Protein-protein interaction networks, Cell biology, 030104 developmental biology, Cytoplasm, Multiprotein Complexes, 030220 oncology & carcinogenesis, Proteolysis, biology.protein, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0431e0ab4ac7de3628e3a278425adbTest
http://link.springer.com/article/10.1038/s41598-020-58087-3Test