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المؤلفون: Joyce Liu, Jordan Downey, Ryan Khalaf, Nicolaus A. Herman, Michio Sato, Hiroyuki Koshino, Wenlong Cai, Frederick F. Twigg, Xuejun Zhu, Joelle Martin, Nicholas C. Harris, Wenjun Zhang
المصدر: Proceedings of the National Academy of Sciences. 114:7025-7030
مصطلحات موضوعية: 0301 basic medicine, Catalysis, Condensation domain, Acylation, Lipopeptides, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Thioesterase, Biosynthesis, Nonribosomal peptide, Gene cluster, Escherichia coli, Peptide Synthases, Gene, chemistry.chemical_classification, Chromatography, Multidisciplinary, Chemistry, Lysine, Fatty Acids, Lipopeptide, Biological Transport, Mycobacterium tuberculosis, Biological Sciences, Chromatography, Ion Exchange, Actinobacteria, 030104 developmental biology, Biochemistry, Metals, Multigene Family, Mutation, Mycobacterium marinum, Ribosomes, Gene Deletion
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1faf4c81d0d5020bb4eb67a3ed6ab672Test
https://doi.org/10.1073/pnas.1705016114Test -
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المؤلفون: Joyce Liu, Ryan Khalaf, Joelle Martin, Hiroyuki Koshino, Jordan Downey, Wenlong Cai, Michio Sato, Wenjun Zhang, Nicholas C. Harris, Nicolaus A. Herman, Frederick F. Twigg
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Lipopeptide, Peptide, Biology, 01 natural sciences, 0104 chemical sciences, 3. Good health, Acylation, Condensation domain, 03 medical and health sciences, chemistry.chemical_compound, Thioesterase, chemistry, Biosynthesis, Biochemistry, Gene cluster, Gene, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e128ef65d1184d0f263bac99a816fae6Test
https://doi.org/10.1101/121228Test -
3دورية أكاديمية
المؤلفون: Rachel Hemingway, Steven W. Baertschi, David Benstead, John M. Campbell, Maggie Coombs, Zongyun Huang, Ryan Khalaf, Martin A. Ott, David J. Ponting, Darren L. Reid, Neil G. Stevenson, Samuel J. Webb, Angela White, Todd Zelesky
مصطلحات موضوعية: Biochemistry, Microbiology, Pharmacology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, term stability studies, small organic molecules, aid pharmaceutical development, 25 drug substances, unknown degradation products, predict degradation pathways, pharmaceutical degradation pathways, given degradation product, forced degradation studies, confirm experimental data, historic knowledge base, benchmarking study using, also evaluated using, knowledge base, degradation profiles, chemical degradation, prediction data, zeneth predictions, transformation types, study group, silico <, predictive capability
الإتاحة: https://doi.org/10.1021/acs.oprd.3c00344.s001Test
https://figshare.com/articles/journal_contribution/_i_In_Silico_i_Prediction_of_Pharmaceutical_Degradation_Pathways_A_Benchmarking_Study_Using_the_Software_Program_Zeneth/25246164Test