نتائج البحث - "Joachim W. Ellwart"

1

Inhibition of Ataxia Telangiectasia- and Rad3 -Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells Through Depletion of the CD133+ Tumor-Initiating Cell Fraction

المؤلفون: Maria-Theresa Mueller, Fred Bunz, Juan G. Machado, Eike Gallmeier, Joachim W. Ellwart, Enrico N. De Toni, Christian Eisen, Christopher Heeschen, Belen Rubio-Viqueira, Andreas Ziesch, Burkhard Göke, Manuel Hidalgo, Jose Rivera, Patrick C. Hermann, Andreas Palagyi

المصدر: STEM CELLS
STEM CELLS; Vol 29
Stem Cells 29, 418-429 (2011)

مصطلحات موضوعية: Somatic cell, Cell, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Cell Separation, Mice, 0302 clinical medicine, AC133 Antigen, Molecular Targeted Therapy, RNA, Small Interfering, 0303 health sciences, Kinase, Cell cycle, 3. Good health, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, medicine.anatomical_structure, Biochemistry, 030220 oncology & carcinogenesis, Colonic Neoplasms, embryonic structures, Neoplastic Stem Cells, Molecular Medicine, Female, biological phenomena, cell phenomena, and immunity, Down-Regulation, Mice, Nude, ATR, Cancer stem cells, Colon cancer, DNA-damage response, Tumor-initiating cells, Protein Serine-Threonine Kinases, Biology, 03 medical and health sciences, Antigens, CD, Cancer stem cell, Cell Line, Tumor, medicine, Animals, Humans, Glycoproteins, 030304 developmental biology, Carcinoma, Genetic Therapy, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, Cell culture, Ataxia-telangiectasia, Cancer research, Peptides, Ataxia telangiectasia and Rad3 related, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295e835de87b558e6cdbd2dd4774700fTest
https://doi.org/10.1002/stem.595Test

2

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

المؤلفون: Elfriede Noessner, Rolf D. Issels, Peter J. Nelson, Frank Momburg, Joachim W. Ellwart, Boris-Christian Marincek, Henriette Bendz

المصدر: J. Biol. Chem. 283, 26477-26483 (2008)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031816dcf38a5d73022ad3d28bcc95bdTest
https://doi.org/10.1074/jbc.m803310200Test

3

Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD–transformed hematopoietic cells

المؤلفون: Tobias M. Kohl, Sabine Eichenlaub, Karsten Spiekermann, Ksenia Bagrintseva, Wolfgang Hiddemann, Ruth Schwab, Susanne Schnittger, Joachim W. Ellwart

المصدر: Blood 103, 2266-2275 (2004)

مصطلحات موضوعية: Antimetabolites, Antineoplastic, Indoles, MAP Kinase Signaling System, Immunology, Antineoplastic Agents, Apoptosis, Biology, medicine.disease_cause, Biochemistry, fluids and secretions, Proto-Oncogene Proteins, hemic and lymphatic diseases, STAT5 Transcription Factor, medicine, Animals, Humans, Enzyme Inhibitors, Phosphorylation, Cell Line, Transformed, Mutation, Cytarabine, Receptor Protein-Tyrosine Kinases, Myeloid leukemia, hemic and immune systems, Cell Biology, Hematology, Tyrphostins, Milk Proteins, Staurosporine, medicine.disease, Genistein, Molecular biology, Protein Structure, Tertiary, DNA-Binding Proteins, Haematopoiesis, Leukemia, Phenotype, fms-Like Tyrosine Kinase 3, Drug Resistance, Neoplasm, Leukemia, Myeloid, Mutagenesis, Cell culture, Acute Disease, embryonic structures, Fms-Like Tyrosine Kinase 3, Trans-Activators, FLT3 Inhibitor, Tyrosine kinase, Cell Division

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6623509c830524d3fcabd255eef79b46Test
https://doi.org/10.1182/blood-2003-05-1653Test

4

KIT exon 8 mutations associated with core-binding factor (CBF)–acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor

المؤلفون: Joachim W. Ellwart, Tobias M. Kohl, Susanne Schnittger, Wolfgang Hiddemann, Karsten Spiekermann

المصدر: Blood 105, 3391 (2005)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcea1acd334139fb06a3bc712ad2c051Test
https://doi.org/10.1182/blood-2004-06-2068Test

5

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons

المؤلفون: Peer-Hendrik Kuhn, Huanhuan Wang, Elisabeth Kremmer, Steffen Roßner, Bastian Dislich, Stefan F. Lichtenthaler, Joachim W. Ellwart, Ulrike Zeitschel, Alessio Colombo

المصدر: EMBO J. 29, 3020-3032 (2010)
The EMBO journal 29(17), 3020-3032 (2010). doi:10.1038/emboj.2010.167

مصطلحات موضوعية: Proteases, ADAM10, Article, Mass Spectrometry, General Biochemistry, Genetics and Molecular Biology, Cell Line, ADAM10 Protein, Amyloid beta-Protein Precursor, Mice, Aplp1 protein, mouse, ddc:570, metabolism [Amyloid beta-Protein Precursor], Adam10 protein, mouse, mental disorders, Amyloid precursor protein, Animals, Humans, Molecular Biology, Neurons, enzymology [Neurons], General Immunology and Microbiology, biology, General Neuroscience, P3 peptide, ADAM, amyloid precursor protein, neuro-degeneration, proteases, alpha-secretase, NECROSIS-FACTOR-ALPHA, METALLOPROTEASE-DISINTEGRIN MDC9, ONSET ALZHEIMERS-DISEASE, BETA-SECRETASE, CONVERTING-ENZYME, HIPPOCAMPAL-NEURONS, CLEAVAGE, APP, ECTODOMAIN, PATHWAY, Membrane Proteins, ADAM Proteins, metabolism [Amyloid Precursor Protein Secretases], Biochemistry of Alzheimer's disease, Alpha secretase, Biochemistry, metabolism [Neurons], metabolism [ADAM Proteins], biology.protein, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, metabolism [Membrane Proteins]

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74366ab201c168b378ab9bae33bfa279Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=6013Test

6

Differential expression of cytokines in human blood monocyte subpopulations [see comments]

المؤلفون: Joachim W. Ellwart, Jürgen Haas, M Strobel, H. W. L. Ziegler-Heitbrock, T Schlunck, G Fingerle, I Petersmann, D Kieper, M Blumenstein

المصدر: Blood. 79:503-511

مصطلحات موضوعية: Messenger RNA, Lipopolysaccharide, Monocyte, medicine.medical_treatment, CD14, Immunology, Cell Biology, Hematology, Biology, CD16, Biochemistry, Molecular biology, chemistry.chemical_compound, medicine.anatomical_structure, Cytokine, chemistry, Interferon, Gene expression, medicine, Interleukin 19, Tumor necrosis factor alpha, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4f42ea0380dd416781893d1429c0acTest
https://doi.org/10.1182/blood.v79.2.503.503Test

7

Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies

المؤلفون: Angela M. Krackhardt, Bernhard Frankenberger, Dirk H. Busch, Ingrid G. Schuster, Elfriede Nössner, Elfriede Eppinger, Elisabeth Kremmer, Christoph Salat, Slavoljub Milosevic, Christian Bogner, Joachim W. Ellwart, Arndt Borkhardt, Christine Hennard, Hans-Jochem Kolb, Christina Kuttler

المصدر: Blood. 110(8)

مصطلحات موضوعية: Cytotoxicity, Immunologic, medicine.medical_treatment, Chronic lymphocytic leukemia, Immunology, Blotting, Western, Receptors, Antigen, T-Cell, Epitopes, T-Lymphocyte, Formins, Enzyme-Linked Immunosorbent Assay, Thymus Gland, Biology, Biochemistry, Peripheral blood mononuclear cell, Immunotherapy, Adoptive, Epitope, Antigen, Antigens, Neoplasm, Bone Marrow, Cell Line, Tumor, medicine, Humans, HLA-A Antigens, Reverse Transcriptase Polymerase Chain Reaction, T-cell receptor, Cell Biology, Hematology, Immunotherapy, medicine.disease, Clone Cells, Cytoskeletal Proteins, Hematologic Neoplasms, Leukocytes, Mononuclear, Stem cell, Clone (B-cell biology), Peptides, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6f285e3919a2b3d5b2727f97b89ab4Test
https://pubmed.ncbi.nlm.nih.gov/17626842Test

8

Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML

المؤلفون: Joachim W. Ellwart, Sridhar Vempati, Karsten Spiekermann, Katja Wenig, Karl-Peter Hopfner, Ksenia Bagrintseva, Susanne Schnittger, Wolfgang Hiddemann, Carola Reindl

مصطلحات موضوعية: Models, Molecular, Immunology, Mutant, Molecular Sequence Data, Apoptosis, In Vitro Techniques, Biology, Biochemistry, Cell Line, Mice, fluids and secretions, hemic and lymphatic diseases, STAT5 Transcription Factor, Animals, Humans, Point Mutation, Amino Acid Sequence, Tyrosine, Phosphorylation, Receptor, STAT5, Base Sequence, Point mutation, Autophosphorylation, Myeloid leukemia, hemic and immune systems, Cell Biology, Hematology, DNA, Neoplasm, Staurosporine, Molecular biology, Recombinant Proteins, Protein Structure, Tertiary, Enzyme Activation, Leukemia, Myeloid, Acute, fms-Like Tyrosine Kinase 3, Fms-Like Tyrosine Kinase 3, embryonic structures, Cancer research, biology.protein, Mutagenesis, Site-Directed, Interleukin-3

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71360bc4ef51b08388742da5c3a2b42dTest

9

The rate of extrachromosomal homologous recombination within a novel reporter plasmid is elevated in cells lacking functional ATM protein

المؤلفون: Friederike Eckardt-Schupp, Eberhard Fritz, Guido A. Drexler, Joachim W. Ellwart, Wolfgang Beisker, Susanne Wilde

المصدر: DNA repair. 3(10)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5052afb1af829ab8828cb9a072c65388Test
https://pubmed.ncbi.nlm.nih.gov/15336629Test

10

Measurement of efflux from G1-phase in a growth factor dependent cell line

المؤلفون: Joachim W. Ellwart, Peter Dörmer

المصدر: Acta biotheoretica. 40(2-3)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c692e782381ffcee568da1a3cba2cdTest
https://pubmed.ncbi.nlm.nih.gov/1462732Test

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