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المؤلفون: Jian Zou, Qiuju Xun, Zhang Zhang, Zhen Wang, Zhengchao Tu, Yingqiang Liu, Linjiang Tong, Hua Xie, Ke Ding, Xiaoyun Lu, Yong Xu, Jinfeng Luo, Minhao Huang
المصدر: Journal of Medicinal Chemistry. 61:2353-2371
مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Biological Availability, Antineoplastic Agents, Rats, Sprague-Dawley, Colony stimulating factor 1 receptor, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, ErbB Receptors, 0302 clinical medicine, Cell Movement, Drug Discovery, Animals, Structure–activity relationship, Epidermal growth factor receptor, Receptor, Protein Kinase Inhibitors, IC50, Molecular Structure, biology, Kinase, Macrophages, Rats, Pyrimidines, RAW 264.7 Cells, 030104 developmental biology, Neutrophil Infiltration, chemistry, Biochemistry, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Drug Design, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a80fbb39b1b47a21f056bddbd73d071Test
https://doi.org/10.1021/acs.jmedchem.7b01612Test -
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المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Male, 0301 basic medicine, Mitochondrial ROS, BAD, Bcl-2-associated death, Apoptosis, ASK1, apoptosis signal-regulating kinase 1, Biochemistry, Monocytes, Idiopathic pulmonary fibrosis, MMVF, man-made vitreous fiber, Fibrosis, Pulmonary fibrosis, AEC, alveolar epithelial cell, Phosphorylation, Lung, chemistry.chemical_classification, monocyte-derived macrophages, NOX4, Environmental exposure, BMDM, bone-marrow-derived macrophage, Mitochondria, NADPH Oxidase 4, Disease Progression, cardiovascular system, Female, bcl-Associated Death Protein, Research Article, PKB, protein kinase B, Models, Biological, Cell Line, apoptosis resistance, 03 medical and health sciences, ROS, reactive oxygen species, Csf1r, colony-stimulating factor 1 receptor, medicine, IPF, idiopathic pulmonary fibrosis, RAM, resident alveolar macrophage, Animals, NOX4, NADPH oxidase 4, Molecular Biology, Reactive oxygen species, pulmonary fibrosis, 030102 biochemistry & molecular biology, urogenital system, business.industry, Macrophages, Cell Biology, medicine.disease, Idiopathic Pulmonary Fibrosis, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Cancer research, MDM, monocyte-derived macrophage, Reactive Oxygen Species, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73149e7282c603c69a710a06ba330859Test
https://doi.org/10.1016/j.jbc.2021.100810Test -
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المؤلفون: Changhua Li, Xiaoping Liu, Fu Hua, Ye Tian, Yingchun Gao
المصدر: Molecular Medicine Reports
مصطلحات موضوعية: 0301 basic medicine, Adult, Cancer Research, Cell, Gene Expression, Biochemistry, Colony stimulating factor 1 receptor, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, colony-stimulating factor 1 receptor, Genetics, Humans, Protein kinase B, Molecular Biology, Aged, Cell Proliferation, colony-stimulating factor 1, U937 cell, Chemistry, Cell growth, tumor-associated macrophages, Macrophage Colony-Stimulating Factor, Macrophages, Endothelial Cells, Articles, Cell cycle, Middle Aged, Colony-stimulating factor, Cell biology, Endometrial Neoplasms, 030104 developmental biology, medicine.anatomical_structure, Oncology, Cell culture, 030220 oncology & carcinogenesis, endometrial cancer, Molecular Medicine, Female, Corrigendum, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a043ca6410c8cb2ffacfa300931918e4Test
https://doi.org/10.3892/mmr.2020.11197Test -
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المؤلفون: Laura E. Kuil, Woutje M. Berdowski, Elly M. Hol, Mark H. G. Verheijen, John C. van Swieten, Herma C. van der Linde, Tjakko J. van Ham, Wilfred F. J. van IJcken, Saskia M. Burm, Nynke Oosterhof
المساهمون: Netherlands Institute for Neuroscience (NIN), Hubrecht Institute for Developmental Biology and Stem Cell Research, Molecular and Cellular Neurobiology, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Clinical Genetics, Cell biology, Neurology, Human genetics
المصدر: Cell reports, 24(5), 1203-1217.e6. CELL PRESS
Cell Reports, 24(5), 1203-1217.e6. Cell Press
Cell Reports, 24(5), 1203-+. Cell Press
Oosterhof, N, Kuil, L E, van der Linde, H C, Burm, S M, Berdowski, W, van Ijcken, W F J, van Swieten, J C, Hol, E M, Verheijen, M H G & van Ham, T J 2018, ' Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo ', Cell Reports, vol. 24, no. 5, pp. 1203-1217.e6 . https://doi.org/10.1016/j.celrep.2018.06.113Test
Cell Reports, 24(5), 1203. Cell Pressمصطلحات موضوعية: 0301 basic medicine, leukodystrophy, microglia, Biochemistry, General Biochemistry, Genetics and Molecular Biology, Colony stimulating factor 1 receptor, Pathogenesis, 03 medical and health sciences, transcriptomics, Leukoencephalopathies, Microglia differentiation, medicine, Journal Article, colony-stimulating factor 1 receptor, Animals, Humans, Receptor, Zebrafish, ALSP, biology, Microglia, Biochemistry, Genetics and Molecular Biology(all), Leukodystrophy, Neurodegeneration, neurodegeneration, Receptor Protein-Tyrosine Kinases, Cell Differentiation, Protein-Tyrosine Kinases, Zebrafish Proteins, CSF1R, medicine.disease, biology.organism_classification, zebrafish, Cell biology, macrophages, 030104 developmental biology, medicine.anatomical_structure, nervous system, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Mutation, HDLS, Genetics and Molecular Biology(all)
وصف الملف: application/pdf; image/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e92216fc7ecf7d504a374d3a16f848Test
https://research.rug.nl/en/publications/d13ced50-3248-4e49-a613-3b2f3d36a7b0Test -
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المؤلفون: Jung Wuk Lee, Jiwon Park, Jihyung Kim, Jina Kim, Changyu Choi, Kyung Hoon Min
المصدر: European Journal of Medicinal Chemistry. 216:113298
مصطلحات موضوعية: Cell Survival, Pyridines, Regulator, 01 natural sciences, Colony stimulating factor 1 receptor, Mice, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Moiety, Phosphorylation, Receptor, Protein Kinase Inhibitors, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Chemistry, Kinase, Macrophages, Organic Chemistry, Cancer, General Medicine, medicine.disease, 0104 chemical sciences, RAW 264.7 Cells, Enzyme, Biochemistry, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Drug Design, Pyrazoles
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7258795acb12cd94d27f4e9a3370148cTest
https://doi.org/10.1016/j.ejmech.2021.113298Test -
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المؤلفون: Kevin P. Cusack, David B. Duignan, Jacqueline Loud, Michael Z. Hoemann, Lu Wang, Kelly D. Mullen, Regina Mario, Jeremy J. Edmunds, Dawn M. George, Gagandeep Somal, Raymond Huntley, Terry Melim
المصدر: PLoS ONE, Vol 13, Iss 9, p e0203567 (2018)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Physiology, Glycobiology, Drug Evaluation, Preclinical, lcsh:Medicine, Pharmacology, Chemical synthesis, Biochemistry, Monocytes, Mass Spectrometry, Analytical Chemistry, White Blood Cells, Mice, 0302 clinical medicine, Spectrum Analysis Techniques, Animal Cells, Medicine and Health Sciences, Prodrugs, Receptor, lcsh:Science, Glucans, chemistry.chemical_classification, Liquid Chromatography, Multidisciplinary, Cyclodextrin, Molecular Structure, Chemistry, Organic Compounds, Chromatographic Techniques, Dextran Sulfate, Pro-Drugs, Drugs, Prodrug, Colitis, Body Fluids, Blood, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, 030220 oncology & carcinogenesis, Physical Sciences, Female, Anatomy, Cellular Types, Research Article, Colon, Immune Cells, Liquid Chromatography-Mass Spectrometry, Immunology, Research and Analysis Methods, Colony stimulating factor 1 receptor, 03 medical and health sciences, Therapeutic index, In vivo, Polysaccharides, medicine, Animals, Dextran, Cyclodextrins, Blood Cells, Macrophages, Organic Chemistry, lcsh:R, Chemical Compounds, Biology and Life Sciences, Cell Biology, medicine.disease, Gastrointestinal Tract, Disease Models, Animal, 030104 developmental biology, Alcohols, lcsh:Q, Digestive System
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4342c0d0784cf989301c8a18f47c3aTest
http://europepmc.org/articles/PMC6128612?pdf=renderTest -
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المصدر: The FASEB Journal. 29:2545-2554
مصطلحات موضوعية: Macrophage colony-stimulating factor, Cells, Immunoblotting, Receptor, Macrophage Colony-Stimulating Factor, Biochemistry, Dinoprostone, Receptor tyrosine kinase, Cell Line, Dose-Response Relationship, Colony stimulating factor 1 receptor, Mice, Cell Movement, Genetics, Animals, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Molecular Biology, Cells, Cultured, Inflammation, Mitogen-Activated Protein Kinase 1, Cultured, Mitogen-Activated Protein Kinase 3, Dose-Response Relationship, Drug, biology, Kinase, Macrophage Colony-Stimulating Factor, Macrophages, Drug Synergism, Cell biology, Crosstalk (biology), Monocytes/macrophages, Cytokine receptors, Signal transduction, NIH 3T3 Cells, Signal Transduction, Biotechnology, Mitogen-activated protein kinase, biology.protein, lipids (amino acids, peptides, and proteins), Drug, Receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7eb288dd03f1e82d606b90ee360bbbfTest
https://doi.org/10.1096/fj.14-258939Test -
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المؤلفون: Hong Su, Yibiao Wang, Olle Söder, Mi Hou
المصدر: Biochemical Genetics. 52:310-319
مصطلحات موضوعية: Lipopolysaccharides, Male, Gene isoform, Receptor, Macrophage Colony-Stimulating Factor, Biology, Biochemistry, Rats, Sprague-Dawley, Colony stimulating factor 1 receptor, Testis, Genetics, Animals, Protein Isoforms, RNA, Messenger, Receptor, Molecular Biology, Cells, Cultured, Ecology, Evolution, Behavior and Systematics, Messenger RNA, Macrophages, Alternative splicing, Biological activity, General Medicine, Ligand (biochemistry), Molecular biology, Rats, Alternative Splicing, Open reading frame, Animals, Newborn, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd009197ed3e5d1d3c8f3f8d98250956Test
https://doi.org/10.1007/s10528-014-9649-6Test -
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المؤلفون: Kelli P. A. MacDonald, David A. Hume
المصدر: Blood. 119:1810-1820
مصطلحات موضوعية: Macrophage colony-stimulating factor, Myeloid, Immunology, Receptor, Macrophage Colony-Stimulating Factor, Inflammation, Biology, Biochemistry, Immune system, Macrophage Colony-Stimulating Factor 1, medicine, Animals, Humans, Macrophage, Kinase activity, Receptor, Protein Kinase Inhibitors, Myeloid Progenitor Cells, Macrophage Colony-Stimulating Factor, Macrophages, Cell Differentiation, Cell Biology, Hematology, medicine.anatomical_structure, Reperfusion Injury, medicine.symptom, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00397c2eeb214f56e1a87aacea6f578aTest
https://doi.org/10.1182/blood-2011-09-379214Test -
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المؤلفون: Jinsheng Chen, Carl L. Manthey, Kenneth J. Wilson, Marie Mazzulla, Margery A. Chaikin, Christopher J. Molloy, Bruce E. Tomczuk, Edward J. Yurkow, Shelley K. Ballentine, Carsten Schubert, Carl Crysler, Renee L. DesJarlais, Ioanna Petrounia, Robert R. Donatelli, Carl R. Illig, Lisa Boczon, Sanath K. Meegalla, Mark J. Wall, Raymond J. Patch, Mark R. Player
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:2097-2102
مصطلحات موضوعية: Macrophage colony-stimulating factor, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Fluorescence Polarization, Receptor, Macrophage Colony-Stimulating Factor, Quinolones, Biochemistry, Colony stimulating factor 1 receptor, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Structure–activity relationship, RNA, Messenger, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, Molecular Structure, biology, Reverse Transcriptase Polymerase Chain Reaction, Chemistry, Kinase, Macrophage Colony-Stimulating Factor, Macrophages, Cellular Assay, Organic Chemistry, Genes, fos, Rats, Mice, Inbred C57BL, Enzyme inhibitor, biology.protein, Molecular Medicine, Signal transduction, Spleen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8176b1c0c69b0ad2c4b2f6486901881aTest
https://doi.org/10.1016/j.bmcl.2008.01.088Test