يعرض 1 - 10 نتائج من 82 نتيجة بحث عن '"malonyl-CoA"', وقت الاستعلام: 1.39s تنقيح النتائج
  1. 1
    Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4

    المؤلفون: Sander M. Houten, Nihad Achetib, Myriam Baes, Tetyana Dodatko, Carmen Argmann, Sara Violante, Chunli Yu, Frédéric M. Vaz, Hongjie Chen, Carlo W.T. van Roermund, Jacob Hagen, Hans R. Waterham

    مصطلحات موضوعية: 0301 basic medicine, Life Sciences & Biomedicine - Other Topics, PHYTANIC ACID, CARNITINE PALMITOYLTRANSFERASE, Palmitic Acid, ATP-binding cassette transporter, Mitochondrion, Biochemistry, PALMITOYLTRANSFERASE-II DEFICIENCY, MITOCHONDRIAL, Palmitic acid, Mice, chemistry.chemical_compound, 0302 clinical medicine, Peroxisomal Multifunctional Protein-2, Beta oxidation, fatty acid oxidation, Mice, Knockout, biology, Fatty Acids, Lauric Acids, Peroxisome, Recombinant Proteins, Mitochondria, mitochondria, MALONYL-COA, MOUSE-LIVER, BETA-OXIDATION, Oxidation-Reduction, Life Sciences & Biomedicine, Biotechnology, medicine.drug, organellar crosstalk, Biochemistry & Molecular Biology, Peroxisomal Bifunctional Enzyme, PRISTANIC ACID, acylcarnitine, 03 medical and health sciences, ABCD3, Carnitine, Peroxisomes, Genetics, medicine, Animals, Humans, ACETYL MOIETY, Molecular Biology, Biology, Science & Technology, MOLECULAR-CLONING, Carnitine O-Palmitoyltransferase, Research, Membrane Proteins, Cell Biology, Metabolic pathway, HEK293 Cells, 030104 developmental biology, chemistry, biology.protein, ATP-Binding Cassette Transporters, CPT2 deficiency, CRISPR-Cas Systems, 030217 neurology & neurosurgery

    وصف الملف: Print-Electronic

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9257e5d9c1e5b6cd676d0b77300cc2a8Test
    https://lirias.kuleuven.be/handle/123456789/640719Test


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  2. 2
    Cloning and expression of the liver and muscle isoforms of ovine carnitine palmitoyltransferase 1: residues within the N-terminus of the muscle isoform influence the kinetic properties of the enzyme

    المؤلفون: Victor A. Zammit, Maureen T. Travers, Vicky N. Jackson, Beatrijs Bartelds, Nigel T. Price, Nicolette C. A. Huijkman, Feike R van der Leij, Jacqueline M. Cameron

    المساهمون: Cardiovascular Centre (CVC)

    المصدر: Biochemical Journal, 372, 871-879. PORTLAND PRESS LTD

    مصطلحات موضوعية: PROMOTER, MALONYL-COA SENSITIVITY, Biochemistry, Conserved sequence, chemistry.chemical_compound, malonyl-CoA, acyltransferase, Tissue Distribution, Cloning, Molecular, Promoter Regions, Genetic, Peptide sequence, Conserved Sequence, GENE-EXPRESSION, BROWN ADIPOSE-TISSUE, Muscles, Nucleic acid sequence, Isoenzymes, fatty acid metabolism, Liver, HEART, CPT-I-ALPHA, Research Article, medicine.drug, DNA, Complementary, CHROMOSOMAL LOCALIZATION, Sequence analysis, Recombinant Fusion Proteins, Molecular Sequence Data, RAT-LIVER, Biology, CDNA CLONING, Carnitine palmitoyltransferase 1, Complementary DNA, medicine, Animals, Humans, Amino Acid Sequence, Carnitine, Molecular Biology, Sheep, Carnitine O-Palmitoyltransferase, Sequence Analysis, DNA, Cell Biology, Blotting, Northern, Molecular biology, Rats, Kinetics, Malonyl-CoA, chemistry, Cattle, BETA GENE

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164c320d8102eee95cb441f7dab4bfa7Test
    https://doi.org/10.1042/bj20030086Test


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  3. 3
    Impaired Mitochondrial Fatty Acid Oxidative Flux in Fibroblasts from a Patient with Malonyl-CoA Decarboxylase Deficiency

    المؤلفون: Richard L. Boriack, Michael J. Bennett, Jonathan Cohen, Pamela A. Harthcock

    المصدر: Molecular Genetics and Metabolism. 73:276-279

    مصطلحات موضوعية: Male, DNA, Complementary, Carboxy-Lyases, Endocrinology, Diabetes and Metabolism, Palmitic Acid, Myristic acid, macromolecular substances, Oxidative phosphorylation, Biochemistry, chemistry.chemical_compound, Endocrinology, Carnitine palmitoyltransferase 1, Genetics, medicine, Malonyl-CoA decarboxylase deficiency, Humans, Child, Molecular Biology, Beta oxidation, Cells, Cultured, Skin, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Fatty Acids, Fatty acid, Exons, Malonyl-CoA decarboxylase, Fibroblasts, medicine.disease, Mitochondria, Oxygen, enzymes and coenzymes (carbohydrates), Phenotype, chemistry, Inborn error of metabolism, lipids (amino acids, peptides, and proteins), Myristic Acids

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5548c2043be923f564d8a8a6377e7567Test
    https://doi.org/10.1006/mgme.2001.3196Test


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  4. 4
    An Environment-dependent Structural Switch Underlies the Regulation of Carnitine Palmitoyltransferase 1A

    المؤلفون: Sara Estolt-Povedano, Gemma Z. L. Warren, Victor A. Zammit, Jampani Nageswara Rao, Tobias S. Ulmer

    المصدر: Journal of Biological Chemistry. 286:42545-42554

    مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular Sequence Data, Molecular Conformation, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, Mice, chemistry.chemical_compound, Protein structure, Carnitine palmitoyltransferase 1, Animals, Humans, Transferase, Amino Acid Sequence, Carnitine O-palmitoyltransferase, Molecular Biology, Beta oxidation, Micelles, Fatty acid synthesis, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Dose-Response Relationship, Drug, Sequence Homology, Amino Acid, Fatty Acids, Fatty acid, Cell Biology, Mitochondria, Protein Structure, Tertiary, Rats, Oxygen, Malonyl-CoA, chemistry, Mitochondrial Membranes, Protein Structure and Folding, Biophysics

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d617edb8c6854f48046add006c369c3fTest
    https://doi.org/10.1074/jbc.m111.306951Test


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  5. 5
    Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle

    المؤلفون: E D Saggerson, N Alam

    المصدر: Biochemical Journal. 334:233-241

    مصطلحات موضوعية: Male, medicine.medical_specialty, Carboxy-Lyases, Palmitic Acid, In Vitro Techniques, Models, Biological, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Malate Dehydrogenase, Internal medicine, medicine, Animals, Carnitine, Enzyme Inhibitors, Muscle, Skeletal, Molecular Biology, Beta oxidation, Soleus muscle, Carnitine O-Palmitoyltransferase, biology, Chemistry, Skeletal muscle, Cell Biology, Malonyl-CoA decarboxylase, Rats, Malonyl Coenzyme A, Kinetics, Fatty acid synthase, Glucose, medicine.anatomical_structure, Endocrinology, Malonyl-CoA, ATP Citrate (pro-S)-Lyase, biology.protein, Epoxy Compounds, Regression Analysis, lipids (amino acids, peptides, and proteins), Acyl Coenzyme A, Fatty Acid Synthases, Oxidation-Reduction, Etomoxir, Research Article, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64420a1812a25b6bae86566e4e4a5e4Test
    https://doi.org/10.1042/bj3340233Test


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  6. 6
    Modulation of the hepatic malonyl-CoA–carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids

    المؤلفون: Carina Prip-Buus, Jean Girard, Martin Sournac, Catherine Esnous, Isabelle Cohen, Marie Akkaoui, Véronique Lenoir

    المساهمون: Peer, Hal, Institut Cochin (UMR_S567 / UMR 8104), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Centre National de la Recherche Scientifique (CNRS)

    المصدر: Biochemical Journal
    Biochemical Journal, 2009, 420 (3), pp.429-438. ⟨10.1042/BJ20081932⟩
    Biochemical Journal, Portland Press, 2009, 420 (3), pp.429-438. 〈10.1042/BJ20081932〉

    مصطلحات موضوعية: Male, medicine.medical_treatment, Fluorescent Antibody Technique, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Insulin, Beta oxidation, fatty acid oxidation, Cells, Cultured, 0303 health sciences, Fatty Acids, Mitochondria, Liver, 030220 oncology & carcinogenesis, Lipogenesis, lipids (amino acids, peptides, and proteins), Oxidation-Reduction, medicine.medical_specialty, Genetic Vectors, Immunoblotting, carnitine palmitoyltransferase 1, Biology, Transfection, Models, Biological, Adenoviridae, 03 medical and health sciences, Carnitine palmitoyltransferase 1, Internal medicine, medicine, Animals, triglyceride, Carnitine O-palmitoyltransferase, Rats, Wistar, Glycogen synthase, Molecular Biology, lipogenesis, Triglycerides, 030304 developmental biology, Carnitine O-Palmitoyltransferase, Triglyceride, Cell Biology, Lipid Metabolism, Rats, Glucose, Endocrinology, Malonyl-CoA, chemistry, Mutation, Hepatocytes, biology.protein

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a879788b9626afd81144d52583a294Test
    https://doi.org/10.1042/bj20081932Test


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  7. 7
    Structural insight into function and regulation of carnitine palmitoyltransferase

    المؤلفون: Ralf Thoma, Arne C. Rufer, Michael Hennig

    المصدر: Cellular and Molecular Life Sciences. 66:2489-2501

    مصطلحات موضوعية: Models, Molecular, endocrine system, endocrine system diseases, Protein Conformation, Carbohydrate metabolism, Biology, Cellular and Molecular Neuroscience, chemistry.chemical_compound, medicine, Animals, Humans, Tissue Distribution, heterocyclic compounds, Carnitine, Inner mitochondrial membrane, neoplasms, Molecular Biology, Pharmacology, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Molecular Structure, Drug discovery, Fatty Acids, Fatty acid, Cell Biology, digestive system diseases, Mitochondria, Isoenzymes, Molecular Weight, Enzyme, Malonyl-CoA, Diabetes Mellitus, Type 2, chemistry, Biochemistry, Gluconeogenesis, Mitochondrial Membranes, Molecular Medicine, Protein Processing, Post-Translational, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1781ba5e65a176b8cc08625ca258e957Test
    https://doi.org/10.1007/s00018-009-0035-1Test


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  8. 8
    A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme

    المؤلفون: Joana Relat, Magdalena Pujol-Vidal, Diego Haro, Pedro F. Marrero

    المصدر: FEBS Journal. 276:210-218

    مصطلحات موضوعية: chemistry.chemical_classification, macromolecular substances, Cell Biology, Glutamic acid, Biology, Biochemistry, Molecular biology, Amino acid, enzymes and coenzymes (carbohydrates), chemistry.chemical_compound, Enzyme, Malonyl-CoA, Carnitine palmitoyltransferase 1, chemistry, medicine, lipids (amino acids, peptides, and proteins), Carnitine O-palmitoyltransferase, Carnitine, Molecular Biology, Beta oxidation, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::68192ab6e80006d90a5c810bd3d8fb12Test
    https://doi.org/10.1111/j.1742-4658.2008.06774.xTest


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  9. 9
    Definition by Functional and Structural Analysis of Two Malonyl-CoA Sites in Carnitine Palmitoyltransferase 1A

    المؤلفون: Fausto G. Hegardt, Guillermina Asins, Eduardo López-Viñas, Montserrat Morillas, Chandrashekaran Gurunathan, Dolors Serra, Paulino Gómez-Puertas, Dolores de Arriaga, Assia Bentebibel

    المصدر: Journal of Biological Chemistry. 282:18212-18224

    مصطلحات موضوعية: Stereochemistry, Molecular Sequence Data, Kinetics, Mutant, Molecular Conformation, Saccharomyces cerevisiae, macromolecular substances, Biology, Biochemistry, Inhibitory Concentration 50, chemistry.chemical_compound, Carnitine palmitoyltransferase 1, Carnitine, medicine, Humans, Amino Acid Sequence, Binding site, Molecular Biology, Palmitoylcarnitine, Binding Sites, Carnitine O-Palmitoyltransferase, Sequence Homology, Amino Acid, Cell Biology, Protein Structure, Tertiary, Malonyl Coenzyme A, A-site, Malonyl-CoA, chemistry, Mutation, lipids (amino acids, peptides, and proteins), Protein Binding, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964403a91a8d726be68ed2813161d688Test
    https://doi.org/10.1074/jbc.m700885200Test


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  10. 10
    Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding

    المؤلفون: Jianying Shi, Gebre Woldegiorgis, Jia Dai, Michelle Treber, Hongfa Zhu, Dennis N. Arvidson

    المصدر: Archives of Biochemistry and Biophysics. 413:67-74

    مصطلحات موضوعية: Molecular Sequence Data, Biophysics, macromolecular substances, In Vitro Techniques, Biochemistry, Pichia, Serine, chemistry.chemical_compound, Valine, Humans, Amino Acid Sequence, Enzyme Inhibitors, Molecular Biology, Sequence Deletion, chemistry.chemical_classification, Alanine, Base Sequence, Carnitine O-Palmitoyltransferase, Chemistry, Myocardium, Wild type, DNA, Recombinant Proteins, Amino acid, Malonyl Coenzyme A, Kinetics, enzymes and coenzymes (carbohydrates), Malonyl-CoA, Amino Acid Substitution, Mutagenesis, Site-Directed, lipids (amino acids, peptides, and proteins), Carnitine palmitoyltransferase I, Leucine

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e87e364e30370eb0132eb1063e57b7Test
    https://doi.org/10.1016/s0003-9861Test(03)00081-x


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