يعرض 1 - 10 نتائج من 37 نتيجة بحث عن '"malonyl-CoA"', وقت الاستعلام: 0.90s تنقيح النتائج
  1. 1
    Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis

    المؤلفون: Carina Prip-Buus, Isabel Tavares de Almeida, Lodewijk IJlst, Margarida F. B. Silva, C. C. P. Aires, Marinus Duran, Femke S. Stet, Ronald J.A. Wanders

    المساهمون: Laboratory Genetic Metabolic Disease, University of Amsterdam [Amsterdam] (UvA)-Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), University of Amsterdam [Amsterdam] (UvA), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC), Laboratoy Genetic Metabolic Diseases, Department of Clinical Chemistry, Academic Medical Centre, University of Amsterdam, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases, University of Amsterdam [Amsterdam] (UvA)-University of Amsterdam [Amsterdam] (UvA), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)

    المصدر: Biochemical Pharmacology
    Biochemical Pharmacology, Elsevier, 2010, 79 (5), pp.792-799. ⟨10.1016/j.bcp.2009.10.011⟩
    Biochemical pharmacology, 79(5), 792-799. Elsevier Inc.

    مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Saccharomyces cerevisiae, Transfection, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Animals, Humans, Transferase, Carnitine O-palmitoyltransferase, Carnitine, Enzyme Inhibitors, Beta oxidation, Cells, Cultured, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Carnitine O-Palmitoyltransferase, biology, Valproic Acid, Fatty Acids, Fibroblasts, Rats, Fatty Liver, Enzyme, Malonyl-CoA, Mechanism of action, chemistry, Enzyme inhibitor, biology.protein, Anticonvulsants, lipids (amino acids, peptides, and proteins), Acyl Coenzyme A, medicine.symptom, Oxidation-Reduction, 030217 neurology & neurosurgery, Plasmids, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b11a427753f1ae8127c34e744833f1eTest
    https://doi.org/10.1016/j.bcp.2009.10.011Test


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  2. 2
    Structural insight into function and regulation of carnitine palmitoyltransferase

    المؤلفون: Ralf Thoma, Arne C. Rufer, Michael Hennig

    المصدر: Cellular and Molecular Life Sciences. 66:2489-2501

    مصطلحات موضوعية: Models, Molecular, endocrine system, endocrine system diseases, Protein Conformation, Carbohydrate metabolism, Biology, Cellular and Molecular Neuroscience, chemistry.chemical_compound, medicine, Animals, Humans, Tissue Distribution, heterocyclic compounds, Carnitine, Inner mitochondrial membrane, neoplasms, Molecular Biology, Pharmacology, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Molecular Structure, Drug discovery, Fatty Acids, Fatty acid, Cell Biology, digestive system diseases, Mitochondria, Isoenzymes, Molecular Weight, Enzyme, Malonyl-CoA, Diabetes Mellitus, Type 2, chemistry, Biochemistry, Gluconeogenesis, Mitochondrial Membranes, Molecular Medicine, Protein Processing, Post-Translational, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1781ba5e65a176b8cc08625ca258e957Test
    https://doi.org/10.1007/s00018-009-0035-1Test


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  3. 3
    A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme

    المؤلفون: Joana Relat, Magdalena Pujol-Vidal, Diego Haro, Pedro F. Marrero

    المصدر: FEBS Journal. 276:210-218

    مصطلحات موضوعية: chemistry.chemical_classification, macromolecular substances, Cell Biology, Glutamic acid, Biology, Biochemistry, Molecular biology, Amino acid, enzymes and coenzymes (carbohydrates), chemistry.chemical_compound, Enzyme, Malonyl-CoA, Carnitine palmitoyltransferase 1, chemistry, medicine, lipids (amino acids, peptides, and proteins), Carnitine O-palmitoyltransferase, Carnitine, Molecular Biology, Beta oxidation, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::68192ab6e80006d90a5c810bd3d8fb12Test
    https://doi.org/10.1111/j.1742-4658.2008.06774.xTest


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  4. 4
    Pig Liver Carnitine Palmitoyltransferase I, with Low Km for Carnitine and High Sensitivity to Malonyl-CoA Inhibition, Is a Natural Chimera of Rat Liver and Muscle Enzymes

    المؤلفون: Pedro F. Marrero, Diego Haro, Fausto G. Hegardt, Gebre Woldegiorgis, Carine Nicot

    المصدر: Biochemistry. 40:2260-2266

    مصطلحات موضوعية: DNA, Complementary, Swine, Molecular Sequence Data, Mitochondria, Liver, Biology, Biochemistry, Isozyme, Pichia, Mice, chemistry.chemical_compound, Carnitine, medicine, Animals, Humans, Carnitine palmitoyltransferase II, Amino Acid Sequence, Carnitine O-palmitoyltransferase, Cloning, Molecular, Enzyme Inhibitors, chemistry.chemical_classification, Base Sequence, Carnitine O-Palmitoyltransferase, Molecular biology, Mitochondria, Muscle, Rats, Amino acid, Isoenzymes, Malonyl Coenzyme A, Kinetics, Malonyl-CoA, Enzyme, chemistry, Organ Specificity, Carnitine palmitoyltransferase I, Sequence Alignment, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b81c09e5605ed558f79020675c627a6Test
    https://doi.org/10.1021/bi0024106Test


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  5. 5
    Identification of Positive and Negative Determinants of Malonyl-CoA Sensitivity and Carnitine Affinity within the Amino Termini of Rat Liver- and Muscle-type Carnitine Palmitoyltransferase I

    المؤلفون: Victor A. Zammit, Vicky N. Jackson, Nigel T. Price

    المصدر: Journal of Biological Chemistry. 275:38410-38416

    مصطلحات موضوعية: Gene isoform, Mutant, Biology, Biochemistry, Pichia, Pichia pastoris, chemistry.chemical_compound, Carnitine, medicine, Animals, Cloning, Molecular, Muscle, Skeletal, Molecular Biology, Sequence Deletion, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Mutagenesis, Cell Biology, biology.organism_classification, Molecular biology, Peptide Fragments, Recombinant Proteins, Rats, Malonyl Coenzyme A, Kinetics, Malonyl-CoA, Enzyme, Liver, chemistry, Mutagenesis, Site-Directed, Carnitine palmitoyltransferase I, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a3737e07c7ef93156845fca1f55cafTest
    https://doi.org/10.1074/jbc.m007722200Test


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  6. 6
    Roles of the N- and C-terminal domains of carnitine palmitoyltransferase I isoforms in malonyl-CoA sensitivity of the enzymes: insights from expression of chimaeric proteins and mutation of conserved histidine residues

    المؤلفون: S. T. Swanson, Daniel W. Foster, J. D. McGarry, N. F. Brown

    المصدر: Biochemical Journal. 335:513-519

    مصطلحات موضوعية: Recombinant Fusion Proteins, macromolecular substances, Biology, Transfection, Biochemistry, chemistry.chemical_compound, medicine, Animals, Point Mutation, Histidine, Amino Acid Sequence, Carnitine, Molecular Biology, Conserved Sequence, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Cell Biology, Ligand (biochemistry), Peptide Fragments, Rats, Isoenzymes, Malonyl Coenzyme A, Kinetics, Enzyme, Malonyl-CoA, Amino Acid Substitution, chemistry, Mitochondrial matrix, COS Cells, Mutagenesis, Site-Directed, Epoxy Compounds, Carnitine palmitoyltransferase I, Etomoxir, Research Article, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310461204974ad05d3bcdb3985566df6Test
    https://doi.org/10.1042/bj3350513Test


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  7. 7
    Mammalian mitochondrial β-oxidation

    المؤلفون: Morteza Pourfarzam, Kim Bartlett, Simon Eaton

    المصدر: ResearcherID
    Scopus-Elsevier

    مصطلحات موضوعية: Dehydrogenase, Mitochondrion, Biology, Models, Biological, Biochemistry, Lipid Metabolism, Inborn Errors, chemistry.chemical_compound, Acyl-CoA Dehydrogenases, Coenzyme A Ligases, medicine, Animals, Humans, Transferase, Carnitine, Molecular Biology, Beta oxidation, Mammals, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, Fatty Acids, Cell Biology, Mitochondria, Malonyl-CoA, Enzyme, chemistry, Carnitine palmitoyltransferase I, Oxidation-Reduction, Research Article, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5796e15dcb7f43bd265a953ef837f88aTest
    https://doi.org/10.1042/bj3200345Test


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  8. 8
    Characterization of the malonyl-CoA-sensitive carnitine palmitoyltransferase (CPTo) of a rat heart mitochondrial particle. Evidence that the catalytic unit is CPTi

    المؤلفون: Loran L. Bieber, E Zaluzec, J Kerner, Douglas A. Gage

    المصدر: Journal of Biological Chemistry. 269:8209-8219

    مصطلحات موضوعية: chemistry.chemical_classification, endocrine system diseases, Protein subunit, Cell Biology, Biology, Biochemistry, digestive system diseases, chemistry.chemical_compound, Enzyme, Malonyl-CoA, chemistry, medicine, heterocyclic compounds, Carnitine O-palmitoyltransferase, Carnitine, Ultracentrifuge, Cell fractionation, neoplasms, Molecular Biology, Polyacrylamide gel electrophoresis, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::fc991cdcf39d0e4fda58fe72000c6fa9Test
    https://doi.org/10.1016/s0021-9258Test(17)37181-8


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  9. 9
    Packing of transmembrane domain 2 of carnitine palmitoyltransferase-1A affects oligomerization and malonyl-CoA sensitivity of the mitochondrial outer membrane protein

    المؤلفون: Muhammad Hasan, Gemma Z. L. Warren, Zsuzsanna A. Jenei, Ann M. Dixon, Victor A. Zammit

    المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(12)

    مصطلحات موضوعية: Models, Molecular, Amino Acid Motifs, Random hexamer, Biology, In Vitro Techniques, medicine.disease_cause, Biochemistry, Pichia, Pichia pastoris, Mitochondrial Proteins, chemistry.chemical_compound, Genetics, medicine, Escherichia coli, Inner membrane, Animals, Molecular Biology, DNA Primers, chemistry.chemical_classification, Mutation, Base Sequence, Carnitine O-Palmitoyltransferase, biology.organism_classification, Recombinant Proteins, Protein Structure, Tertiary, Rats, Malonyl Coenzyme A, Transmembrane domain, Malonyl-CoA, Enzyme, chemistry, Mitochondrial Membranes, Mutagenesis, Site-Directed, Protein Multimerization, Bacterial outer membrane, Biotechnology

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002d293e58c5ccc67656435cae28c584Test
    https://pubmed.ncbi.nlm.nih.gov/21917985Test


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  10. 10
    Restoration of malonyl-CoA sensitivity of soluble rat liver mitochondria carnitine palmitoyltransferase by reconstitution with a partially purified malonyl-CoA binding protein

    المؤلفون: Barbara Fibich, Lorenzo Contreras, Gebre Woldegiorgis, Earl Shrago

    المصدر: Archives of Biochemistry and Biophysics. 295:348-351

    مصطلحات موضوعية: Biophysics, Mitochondria, Liver, macromolecular substances, Biochemistry, Chromatography, Affinity, chemistry.chemical_compound, Affinity chromatography, medicine, Animals, Carnitine, Sodium dodecyl sulfate, Molecular Biology, Gel electrophoresis, chemistry.chemical_classification, Carnitine O-Palmitoyltransferase, biology, Binding protein, Membrane Proteins, Enzyme assay, Rats, Malonyl Coenzyme A, enzymes and coenzymes (carbohydrates), Malonyl-CoA, Enzyme, chemistry, biology.protein, Electrophoresis, Polyacrylamide Gel, lipids (amino acids, peptides, and proteins), medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a4389d357539c76b4c6884f06d278bTest
    https://doi.org/10.1016/0003-9861Test(92)90527-4


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