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1
المؤلفون: Michael Dördelmann, Martin Schrappe, Sally A. Coulthard, Martin Zimmermann, Michel Eichelbaum, Anja Möricke, A. Reiter, G Cario, André Schrauder, Peter Kaatsch, Martin Stanulla, Karl Welte, Hansjörg Riehm, Matthias Schwab, Elke Schaeffeler
المصدر: Blood. 114:1314-1318
مصطلحات موضوعية: Male, Heterozygote, medicine.medical_specialty, Vincristine, Immunology, Biochemistry, Thiopurine S-Methyltransferase, Risk Factors, Germany, Internal medicine, Acute lymphocytic leukemia, Antineoplastic Combined Chemotherapy Protocols, medicine, Asparaginase, Humans, Child, Childhood Acute Lymphoblastic Leukemia, Genetics, Hematology, Thiopurine methyltransferase, biology, Brain Neoplasms, business.industry, Daunorubicin, Homozygote, Infant, Cancer, Myeloid leukemia, Neoplasms, Second Primary, Methyltransferases, Cell Biology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Leukemia, Myeloid, Acute, Child, Preschool, biology.protein, Prednisone, Female, business, Follow-Up Studies, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fa8227801ce7edaa3294860ca1b02aTest
https://doi.org/10.1182/blood-2008-12-193250Test -
2
المؤلفون: Michel Eichelbaum, Klaus von Bergmann, Dieter Lütjohann, Mikko Niemi, Michael Igel, Kari T. Kivistö, Ute Hofmann, Katja A. Arnold, Matthias Schwab
المصدر: Clinical Pharmacology & Therapeutics. 79:419-426
مصطلحات موضوعية: Adult, medicine.medical_specialty, Organic anion transporter 1, Organic Anion Transporters, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, medicine, Humans, Pharmacology (medical), Prospective Studies, Pravastatin, Pharmacology, Polymorphism, Genetic, biology, Liver-Specific Organic Anion Transporter 1, Cholesterol, Cholesterol, LDL, Confidence interval, Organic anion-transporting polypeptide, Endocrinology, Haplotypes, chemistry, Biochemistry, Pharmacogenetics, Area Under Curve, biology.protein, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, SLCO1B1, Half-Life, Lipoprotein, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8d1067c789c20c065cbd8eea23e6fbTest
https://doi.org/10.1016/j.clpt.2006.01.010Test -
3
المؤلفون: Ulrich M. Zanger, Michel Eichelbaum, Matthias Schwab, Tanja Richter
المصدر: Biochemical Pharmacology. 69:517-524
مصطلحات موضوعية: CYP2B6, ThioTEPA, Pharmacology, Hydroxylation, Biochemistry, law.invention, law, medicine, Humans, Enzyme Inhibitors, Bupropion, biology, Chemistry, Active site, Cytochrome P450, Oxidoreductases, N-Demethylating, Cytochrome P-450 CYP2B6, Mechanism of action, Suicide inhibition, biology.protein, Recombinant DNA, Microsome, Aryl Hydrocarbon Hydroxylases, medicine.symptom, Thiotepa, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d21ad87d3b786d87800f180e1d6e55Test
https://doi.org/10.1016/j.bcp.2004.10.008Test -
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المؤلفون: Martin F. Fromm, Michel Eichelbaum, Oliver Burk, Kari T. Kivistö, Oliver von Richter, Klaus P. Thon
المصدر: Clinical Pharmacology & Therapeutics. 75:172-183
مصطلحات موضوعية: Adult, Male, Enterocyte, Blotting, Western, Statistics, Nonparametric, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Intestine, Small, Cytochrome P-450 CYP3A, medicine, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Aged, P-glycoprotein, Aged, 80 and over, Pharmacology, biology, CYP3A4, Cytochrome P450, Norverapamil, Middle Aged, Molecular biology, Enterocytes, medicine.anatomical_structure, Gene Expression Regulation, chemistry, Biochemistry, Hepatocyte, Hepatocytes, biology.protein, Duodenum, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb8489a61cb545cebcfadb5ba7df9e3Test
https://doi.org/10.1016/j.clpt.2003.10.008Test -
5
المؤلفون: B. Sperker, Heyo K. Kroemer, P. Schwarzmann, Kari T. Kivistö, M. Spath, Peter Fritz, T. E. Murdter, Michel Eichelbaum
المصدر: Xenobiotica. 29:693-702
مصطلحات موضوعية: Adult, Male, Cytoplasm, Health, Toxicology and Mutagenesis, Blotting, Western, Biology, Toxicology, Biochemistry, Reference Values, Biopsy, medicine, Humans, neoplasms, Aged, Glutathione Transferase, Pharmacology, Paraffin Embedding, integumentary system, medicine.diagnostic_test, Liver Diseases, Reproducibility of Results, Cancer, General Medicine, Middle Aged, medicine.disease, Hodgkin Disease, Immunohistochemistry, Phenotype, Molecular biology, Staining, Fatty Liver, Blot, Glutathione S-transferase, Liver, biology.protein, Female, Antibody
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ee10d6d13fec3a985b7058be5461baTest
https://doi.org/10.1080/004982599238326Test -
6
المؤلفون: Klaus Mörike, Michel Eichelbaum, Wolfgang Urban, Peter Fritz, M. Koch
المصدر: Archives of Toxicology. 70:300-305
مصطلحات موضوعية: Male, Magnetic Resonance Spectroscopy, Cytochrome, Nitrogen, Health, Toxicology and Mutagenesis, Metabolite, Pharmacology, Nitric Oxide, Toxicology, Rats, Sprague-Dawley, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, In vivo, medicine, Animals, Biotransformation, Nitrogen Isotopes, biology, Lasers, Cytochrome P450, Exhalation, General Medicine, Nuclear magnetic resonance spectroscopy, Rats, Hydrazines, Liver, chemistry, Biochemistry, Toxicity, biology.protein, Phenobarbital, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f011c09ecfee5f4f236fb9be0b2ebd5bTest
https://doi.org/10.1007/s002040050277Test -
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المؤلفون: Andrew A. Somogyi, Gerd Mikus, Felix Bochner, Michel Eichelbaum
المصدر: Xenobiotica. 21:1501-1509
مصطلحات موضوعية: Thebaine, Health, Toxicology and Mutagenesis, Metabolite, Pharmacology, Toxicology, Methylation, Biochemistry, Mixed Function Oxygenases, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Species Specificity, Oripavine, medicine, Animals, Demethylation, biology, Alkaloid, Cytochrome P450, Rats, Inbred Strains, General Medicine, Rats, Kinetics, Cytochrome P-450 CYP2D6, chemistry, Microsomes, Liver, biology.protein, Morphine, Female, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4111d7223ab6f6a760f3b206445bd09bTest
https://doi.org/10.3109/00498259109044400Test -
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المؤلفون: Jürgen Pleiss, Kathrin Klein, Elisabeth Hustert, Tanja Saussele, Ulrich M. Zanger, Stephan Tatzel, Michel Eichelbaum, Sebastian Raimundo
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 35(8)
مصطلحات موضوعية: Models, Molecular, Heterozygote, Heme binding, Genotype, Sparteine, Pharmaceutical Science, Sequence alignment, Heme, Biology, Arginine, digestive system, Isozyme, Polymorphism, Single Nucleotide, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Gene Frequency, Propafenone, Consensus Sequence, Humans, Amino Acid Sequence, Chromatography, High Pressure Liquid, Pharmacology, Genetics, chemistry.chemical_classification, Binding Sites, Sequence Homology, Amino Acid, Cytochrome P450, Recombinant Proteins, Amino acid, Enzyme, chemistry, Biochemistry, Cytochrome P-450 CYP2D6, biology.protein, Cysteine, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f955e93fcefc50d6fdcab3eac6e2dcTest
https://pubmed.ncbi.nlm.nih.gov/17460029Test -
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المؤلفون: Mikael Oscarson, Ulrich M. Zanger, Kathrin Klein, Urs A. Meyer, Oktay F. Rifki, Michel Eichelbaum
المصدر: Clinical pharmacology and therapeutics. 80(5)
مصطلحات موضوعية: Adult, Male, Receptors, Steroid, Transcription, Genetic, Receptors, Cytoplasmic and Nuclear, Pharmacology, Transactivation, Cytochrome P-450 Enzyme System, In vivo, Constitutive androstane receptor, Humans, Pharmacology (medical), Receptor, Aged, Oligonucleotide Array Sequence Analysis, Pregnane X receptor, Epilepsy, biology, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, Pregnane X Receptor, Cytochrome P450, Middle Aged, Metabolic Detoxication, Phase II, Multidrug Resistance-Associated Protein 2, Carbamazepine, Biochemistry, Nuclear receptor, Gene Expression Regulation, Liver, biology.protein, ATP-Binding Cassette Transporters, Anticonvulsants, Female, Metabolic Detoxication, Phase I, Drug metabolism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2a7155378ac1bf926167fa5e70b6b9Test
https://pubmed.ncbi.nlm.nih.gov/17112801Test -
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المؤلفون: Peter Neuhaus, Ulrich M. Zanger, Andreas K. Nuessler, Yunhai Cui, Kathrin Klein, Jörg König, Michel Eichelbaum, Anne T. Nies, Christoph W. Michalski, Dietrich Keppler
المصدر: The Journal of biological chemistry. 277(45)
مصطلحات موضوعية: Organic anion transporter 1, Mutant, Molecular Sequence Data, Biochemistry, Protein Structure, Secondary, White People, Protein structure, Mutant protein, Complementary DNA, Germany, Humans, Amino Acid Sequence, Molecular Biology, Protein maturation, DNA Primers, chemistry.chemical_classification, Binding Sites, Polymorphism, Genetic, biology, Liver-Specific Organic Anion Transporter 1, Cell Membrane, Cell Biology, Molecular biology, Recombinant Proteins, Amino acid, Kinetics, chemistry, Amino Acid Substitution, Liver, Mutation, biology.protein, Organic anion transport, Hepatocytes
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd44a397004ed26eb97c9da5e3a967eeTest
https://pubmed.ncbi.nlm.nih.gov/12196548Test