In the past, a severe inflammation was a difficulty to complete a laparoscopic cholecystectomy for the increased risk of vasculo-biliary injuries. Today, if in laparoscopy a “critical view of safety” (CVS) is not possible, to avoid damages, several laparoscopic rescue procedures have been proposed. The first one and the most safe is to change technique abandoning the research of CVS to perform a laparoscopic subtotal cholecystectomy. Mandatory is that the decision of changing the surgical strategy should be made before doing vascular or biliary injuries. In this chapter, all the tricks to complete the usual cholecystectomy are reported. But when the safety of the patient is in danger, we report all the alternative laparoscopic techniques to finish the procedure safely. Finally, all the outcomes conclude the chapter.