Synthesis of furo-salicylanilides and their heterocyclic derivatives with anticipated molluscicidal activity

التفاصيل البيبلوغرافية
العنوان: Synthesis of furo-salicylanilides and their heterocyclic derivatives with anticipated molluscicidal activity
المؤلفون: Gehan H. Hegazy, Ghaneya S. Hassan, Hany Mohamed Safwat
المصدر: Archiv der Pharmazie. 339(8)
سنة النشر: 2006
مصطلحات موضوعية: Molluscacides, Stereochemistry, Pharmaceutical Science, Moderate activity, Biomphalaria alexandrina, Chemical synthesis, Pulmonata, Salicylanilides, Structure-Activity Relationship, Drug Discovery, parasitic diseases, Toxicity Tests, Organic chemistry, Animals, Furans, Heterocyclic derivatives, Bicyclic molecule, biology, Biomphalaria, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Intermediate host, General Medicine, Schistosoma mansoni, biology.organism_classification, Solubility, Molluscicide, Niclosamide
الوصف: The synthesis of new furo-salicylanilides and their heterocyclic derivatives is described. Twenty-three compounds were screened for their molluscicidal activity against Biomphalaria alexandrina snails, the intermediate host of Schistosoma mansoni. Five of the tested compounds showed no activity, while eighteen compounds showed strong to moderate activity using bayluscide as a reference.
تدمد: 0365-6233
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9bfb360a8ce44fafa77f62ad6d496fTest
https://pubmed.ncbi.nlm.nih.gov/16832819Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....df9bfb360a8ce44fafa77f62ad6d496f
قاعدة البيانات: OpenAIRE