دورية أكاديمية
164 Early haemodynamic changes and myocardial injury after transfemoral transcatheter aortic valve implantation (TAVI)
| العنوان: | 164 Early haemodynamic changes and myocardial injury after transfemoral transcatheter aortic valve implantation (TAVI) |
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| المؤلفون: | Dworakowski, R, Bhan, A, Brickham, B, Wendler, O, Monaghan, M, Shah, A M, MacCarthy, P |
| بيانات النشر: | British Medical Journal Publishing Group |
| سنة النشر: | 2011 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | BCS Abstracts 2011 |
| الوصف: | Purpose Transfemoral (TF) TAVI is a novel procedure for the treatment of severe aortic stenosis, without the need for thoracotomy or cardiopulmonary bypass. The procedure results in almost instantaneous normalisation of transvalvular gradients, but little is yet known about the periprocedural haemodynamic effects. We aimed to describe these effects using 3D and tissue Doppler (tD) transthoracic echocardiography (TTE) and Cardiac Output monitoring. Methods In 16 patients undergoing TF TAVI haemodynamics were characterised with a number of tD and 3D TTE measurements. These were taken at multiple time points (baseline, 6 and 24 hours post procedure). Calculated volumetric parameters included 3D end-diastolic volume (EDV) and end-systolic volume (ESV), stroke volume (SV) and 3D LA volume (LAV). Diastolic function was monitored using the indices mean E:E′ and systolic function/contractility was measured with dP/dt max and early peak systolic velocity (S′). The FloTrac system (consisting of the Vigileo monitor and sensor), uses a clinically validated algorithm to provide continuous cardiac output (CO), stroke volume (SV) and systemic vascular resistance in real-time. Results TAVI resulted in an immediate increase in cardiac output (3.7 (baseline), 4.6 (6 h) 4.5 l/min (24 h), p<0.5 baseline vs 6 h and 24 h) with no significant change in systemic vascular resistance (1162, 1292 and 1367 dyn*s/cm5). However, 6 h post-TAVI there was a significant decrease in systolic function as measured by dP/dt max/EDV (see |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| العلاقة: | http://heart.bmj.com/cgi/content/short/97/Suppl_1/A91-bTest; http://dx.doi.org/10.1136/heartjnl-2011-300198.164Test |
| DOI: | 10.1136/heartjnl-2011-300198.164 |
| الإتاحة: | https://doi.org/10.1136/heartjnl-2011-300198.164Test http://heart.bmj.com/cgi/content/short/97/Suppl_1/A91-bTest |
| حقوق: | Copyright (C) 2011, BMJ Publishing Group Ltd |
| رقم الانضمام: | edsbas.8B252223 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/heartjnl-2011-300198.164 |
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