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المؤلفون: Hong Wang, Eric A. Wold, Zhuo Yu, Haiying Chen, Tao Yin, Ye Ding, Hye Jin Kim, Xi Liu, Qiang Shen, Chunyong Ding, Gang Liu, Hao Zou, Jia Zhou, Ruping Yan
المصدر: European Journal of Medicinal Chemistry. 178:589-605
مصطلحات موضوعية: Mice, Nude, Antineoplastic Agents, Breast Neoplasms, 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Breast cancer, Drug Discovery, Tumor Cells, Cultured, medicine, Animals, Humans, Structure–activity relationship, Triple-negative breast cancer, Cell Proliferation, bcl-2-Associated X Protein, 030304 developmental biology, Pharmacology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Activator (genetics), Cytochrome c, Organic Chemistry, Mammary Neoplasms, Experimental, General Medicine, medicine.disease, 0104 chemical sciences, Molecular Docking Simulation, Mechanism of action, chemistry, Apoptosis, MCF-7 Cells, biology.protein, Cancer research, Female, Drug Screening Assays, Antitumor, medicine.symptom, Lead compound
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3ee25176481b7f4425fb3c94c3d9a4Test
https://doi.org/10.1016/j.ejmech.2019.06.004Test -
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المؤلفون: Wei Zhou, Maohua Xie, Dongkyoo Park, Jun Zhang, Haian Fu, Rui Li, Zhuo Georgia Chen, Jia Zhou, Xingming Deng, Ye Ding, Adam I. Marcus, Suresh S. Ramalingam, Andrew T. Magis, Chunyong Ding, Fadlo R. Khuri, Melissa Gilbert-Ross, Guo Chen, Walter J. Curran, Shi-Yong Sun, Guojing Zhang, Taofeek K. Owonikoko, Dong M. Shin, Gabriel Sica
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Lung Neoplasms, Cell, Pharmacology, Article, 03 medical and health sciences, Mice, Bcl-2-associated X protein, Cell Line, Tumor, medicine, Animals, Humans, Phosphorylation, Lung cancer, PI3K/AKT/mTOR pathway, Cell Proliferation, bcl-2-Associated X Protein, biology, Cell growth, TOR Serine-Threonine Kinases, Cancer, medicine.disease, Models, Structural, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Oncology, biology.protein, Signal transduction, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953d256787ac33b9fa62b199e5377d29Test
https://europepmc.org/articles/PMC5503158Test/ -
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المؤلفون: Rui Li, Dongkyoo Park, Taofeek K. Owonikoko, Xingming Deng, Andrew T. Magis, Fadlo R. Khuri, Suresh S. Ramalingam, Patrick Corsino, Mark A. White, Walter J. Curran, Meiguo Xin, Maohua Xie, Chunyong Ding, Gabriel Sica, Jia Zhou
المصدر: Nature communications
مصطلحات موضوعية: Male, Lung Neoplasms, Regulator, General Physics and Astronomy, Mice, Nude, Antineoplastic Agents, Apoptosis, Molecular Dynamics Simulation, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, Serine, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, Cell Line, Tumor, Neoplasms, Animals, Humans, Phosphorylation, 030304 developmental biology, bcl-2-Associated X Protein, 0303 health sciences, Multidisciplinary, Binding Sites, biology, Cytochrome c, General Chemistry, Fibroblasts, Small molecule, 3. Good health, Cell biology, Cell culture, 030220 oncology & carcinogenesis, Drug Design, biology.protein, Drug Screening Assays, Antitumor, Protein Multimerization
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995ca11267a68a9fa6ca13159bfe1207Test
http://europepmc.org/articles/PMC4172359Test