Cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid gland tumor
| العنوان: | Cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid gland tumor |
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| المؤلفون: | Manabu Yamashita, Sohsuke Yamada, Akihiro Shioya, Satoko Nakada, Hiroshi Minato, Mariko Nakano, Xin Guo, Nozomu Kurose |
| المصدر: | Diagnostic Pathology, Vol 13, Iss 1, Pp 1-4 (2018) Diagnostic Pathology |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Pathology, medicine.medical_specialty, Skin Neoplasms, Histology, Biopsy, Fine-Needle, Case Report, Pathology and Forensic Medicine, Metastasis, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, stomatognathic system, Predictive Value of Tests, Cytology, Proliferating pilomatricoma, Carcinoma, lcsh:Pathology, Humans, Medicine, Diagnostic Errors, Cell Proliferation, business.industry, Nodule (medicine), Pilomatricoma, General Medicine, Middle Aged, Pilomatrixoma, medicine.disease, Hair follicle, Magnetic Resonance Imaging, Basophilic cells, Parotid Neoplasms, Parotid gland, Basophilic, medicine.anatomical_structure, Shadow cells, 030220 oncology & carcinogenesis, medicine.symptom, Hair Diseases, business, lcsh:RB1-214 |
| الوصف: | Background Pilomatricoma is a relatively common benign cutaneous adnexal neoplasm with differentiation towards the hair matrix, inner sheath of hair follicle and hair cortex. Proliferating pilomatricoma is a rare variant of pilomatricoma that can rapidly increase and may be misidentified as a malignant tumor. We herein report the cytopathological findings of proliferating pilomatricoma misdiagnosed as a malignant parotid tumor. Case presentation A 64-year-old man noticed an acne-like nodule in the left parotid region. It was painless, but it increased to a maximum diameter of 4.5 cm over 2 years. Clinically, left parotid gland carcinoma was suspected, and fine-needle aspiration cytology was performed. Clusters of epithelial cells were observed in a necrotic background, and malignant epithelial cells derived from salivary glands were suspected. Histologically, the resected tumor was diagnosed as proliferating pilomatricoma composed of basophilic cells and shadow cells apart from the parotid gland. However, on a re-evaluation of the cytological specimens, the irregular-shaped epithelial cells were considered to be from basophilic cells. Shadow cells with nuclear disappearance were also confirmed. Tumor recurrence and metastasis have not been observed in the four years since surgery. Conclusion The present case was first interpreted as a malignant parotid gland tumor, but it was actually a benign skin appendage tumor. Pilomatricoma sometimes rapidly increases and may be mistaken for a malignant tumor. Although it is critical to recognize not only basophilic cells but also shadow cells, it cannot be diagnosed by cytological findings. The final diagnosis should be made on excision specimen only. |
| اللغة: | English |
| تدمد: | 1746-1596 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f886aa478ea0ddf148497d20660f8f9bTest http://link.springer.com/article/10.1186/s13000-018-0738-4Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f886aa478ea0ddf148497d20660f8f9b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17461596 |
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