المؤلفون: Adams, Elizabeth J, Karthaus, Wouter R, Hoover, Elizabeth, Liu, Deli, Gruet, Antoine, Zhang, Zeda, Cho, Hyunwoo, DiLoreto, Rose, Chhangawala, Sagar, Liu, Yang, Watson, Philip A, Davicioni, Elai, Sboner, Andrea, Barbieri, Christopher E, Bose, Rohit, Leslie, Christina S, Sawyers, Charles L

المصدر: Nature. 571(7765)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Genetics, Clinical Sciences, Oncology and Carcinogenesis, Urologic Diseases, Prostate Cancer, Cancer, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Amino Acid Sequence, Animals, Base Sequence, Binding Sites, Cell Differentiation, Cell Lineage, Chromatin, Disease Progression, Gene Expression Regulation, Neoplastic, Hepatocyte Nuclear Factor 3-alpha, Humans, Male, Mice, Mice, Inbred NOD, Mutation, Nucleotide Motifs, Organoids, Phenotype, Prostatic Neoplasms, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5jq9v28qTest

المؤلفون: Tan, Yuliang, Jin, Chunyu, Ma, Wubin, Hu, Yiren, Tanasa, Bogdan, Oh, Soohwan, Gamliel, Amir, Ma, Qi, Yao, Lu, Zhang, Jie, Ohgi, Kenny, Liu, Wen, Aggarwal, Aneel K, Rosenfeld, Michael G

المصدر: Molecular Cell. 71(4)

مصطلحات موضوعية: Genetics, Biotechnology, Base Sequence, Binding Sites, CRISPR-Cas Systems, Enhancer Elements, Genetic, Estradiol, Estrogen Receptor alpha, F-Box Proteins, Gene Editing, Gene Expression Regulation, HEK293 Cells, Hepatocyte Nuclear Factor 3-alpha, Histones, Humans, Jumonji Domain-Containing Histone Demethylases, MCF-7 Cells, Nedd4 Ubiquitin Protein Ligases, Protein Binding, RNA, RNA Polymerase II, Signal Transduction, Transcription, Genetic, Ubiquitination, ERα, KDM2A, NEDD4, Pol II, decommission, eRNA, enhancer, nuclear receptor, repression, transcription, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3kg4h6pdTest

المؤلفون: Wei Zheng, Zhishan Chen, Wanqing Wen, Xingyi Guo, Jiandong Bao, Quan Long, Xiao-Ou Shu

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, Risk, Science, genetic processes, Gene regulatory network, General Physics and Astronomy, Breast Neoplasms, Computational biology, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Breast cancer, Cancer epigenetics, Cell Line, Tumor, Genetic variation, medicine, Humans, Gene Regulatory Networks, Genetic Predisposition to Disease, natural sciences, Enhancer, Transcription factor, Multidisciplinary, Base Sequence, Gene Expression Profiling, fungi, Estrogen Receptor alpha, DNA, Neoplasm, General Chemistry, medicine.disease, Chromatin, Gene Expression Regulation, Neoplastic, Gene expression profiling, Enhancer Elements, Genetic, MCF-7 Cells, Female, Transcriptome, E2F1 Transcription Factor, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f0a84fb143684eda18a1bf10e4b4f4Test
https://doi.org/10.1038/s41467-021-25670-9Test

المؤلفون: Binwei Chen, Jianhong Guo, Chuhai Xie, Boyi Wu, Yanming Cao

المصدر: Biomedicine & Pharmacotherapy. 97:1645-1653

مصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, 0301 basic medicine, Down-Regulation, Mice, Nude, Apoptosis, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, MTT assay, Cell Proliferation, Pharmacology, Mice, Inbred BALB C, Osteosarcoma, Gene knockdown, Base Sequence, medicine.diagnostic_test, Oncogene, Cell growth, Chemistry, General Medicine, Up-Regulation, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer research, Female, RNA, Long Noncoding, FOXA1, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4d32d94af27ae86784b6c9c352611cTest
https://doi.org/10.1016/j.biopha.2017.12.004Test

المؤلفون: Rose DiLoreto, Sagar Chhangawala, Charles L. Sawyers, Zeda Zhang, Elizabeth J. Adams, Christopher E. Barbieri, Wouter R. Karthaus, Philip A. Watson, Hyunwoo Cho, Christina S. Leslie, Deli Liu, Elai Davicioni, Antoine Gruet, Yang Liu, Andrea Sboner, Rohit Bose, Elizabeth Hoover

المصدر: Nature, vol 571, iss 7765
Nature

مصطلحات موضوعية: 0301 basic medicine, Male, Hepatocyte Nuclear Factor 3-alpha, Urologic Diseases, General Science & Technology, Mutant, Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Mice, Inbred NOD, Gene expression, Genetics, Animals, Humans, 2.1 Biological and endogenous factors, Cell Lineage, Amino Acid Sequence, Nucleotide Motifs, Aetiology, Transcription factor, Loss function, Cancer, Regulation of gene expression, Neoplastic, Multidisciplinary, Binding Sites, Base Sequence, Prostate Cancer, Human Genome, Prostatic Neoplasms, Cell Differentiation, Phenotype, Molecular biology, Chromatin, Gene Expression Regulation, Neoplastic, Organoids, 030104 developmental biology, Gene Expression Regulation, 030220 oncology & carcinogenesis, Mutation, Disease Progression, Inbred NOD, FOXA1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b849d3535d5fbe91193695c9864e7dTest
https://escholarship.org/uc/item/5jq9v28qTest

المؤلفون: Henk G. van der Poel, Joyce Sanders, Andries M. Bergman, Marjolein Droog, Suzan Stelloo, Wilbert Zwart, Lodewyk F. A. Wessels, Ekaterina Nevedomskaya, Karianne Schuurman, Simon Linder, Abhishek Singh, Yongsoo Kim

المساهمون: Chemical Biology, Pathology, Internal medicine

المصدر: Life Science Alliance, 2(1):e201800115. EMBO Press
Life Science Alliance, 2(1):e201800115. Rockefeller University Press
Life Science Alliance, 2(1)
Singh, A A, Schuurman, K, Nevedomskaya, E, Stelloo, S, Linder, S, Droog, M, Kim, Y, Sanders, J, Van Der Poel, H, Bergman, A M, Wessels, L F A & Zwart, W 2019, ' Optimized ChIP-seq method facilitates transcription factor profiling in human tumors ', Life Science Alliance, vol. 2, no. 1, e201800115 . https://doi.org/10.26508/lsa.201800115Test
Life Science Alliance

مصطلحات موضوعية: 0301 basic medicine, Hepatocyte Nuclear Factor 3-alpha, Male, Health, Toxicology and Mutagenesis, Breast Neoplasms, Plant Science, Computational biology, SDG 3 – Goede gezondheid en welzijn, Biochemistry, Genetics and Molecular Biology (miscellaneous), Sensitivity and Specificity, Histones, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Text mining, SDG 3 - Good Health and Well-being, Prostate, Biopsy, medicine, Methods, Humans, Transcription factor, Binding Sites, Ecology, medicine.diagnostic_test, Base Sequence, business.industry, Chemistry, Prostatic Neoplasms, medicine.disease, Chip, Data Accuracy, Endometrial Neoplasms, 030104 developmental biology, medicine.anatomical_structure, Receptors, Androgen, 030220 oncology & carcinogenesis, MCF-7 Cells, Chromatin Immunoprecipitation Sequencing, Female, Biopsy, Large-Core Needle, FOXA1, business, Chromatin immunoprecipitation, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9608142573a44bc362e870ce64dc566eTest
https://doi.org/10.26508/lsa.201800115Test

المؤلفون: Wen Liu, Kenny Ohgi, Michael G. Rosenfeld, Qi Ma, Jie Zhang, Bogdan Tanasa, Yuliang Tan, Amir Gamliel, Aneel K. Aggarwal, Lu Yao, Chunyu Jin, Yiren Hu, Soohwan Oh, Wubin Ma

المصدر: Molecular cell, vol 71, iss 4

مصطلحات موضوعية: 0301 basic medicine, Jumonji Domain-Containing Histone Demethylases, Transcription, Genetic, Nedd4 Ubiquitin Protein Ligases, KDM2A, RNA polymerase II, Medical and Health Sciences, Histones, 0302 clinical medicine, Demethylase activity, nuclear receptor, ERα, Gene Editing, biology, Estradiol, Biological Sciences, Cell biology, Enhancer Elements, Genetic, MCF-7 Cells, RNA Polymerase II, transcription, Signal Transduction, Protein Binding, Biotechnology, Hepatocyte Nuclear Factor 3-alpha, Enhancer Elements, eRNA, Article, 03 medical and health sciences, Genetic, Pol II, decommission, Genetics, Humans, Enhancer, Molecular Biology, Binding Sites, Base Sequence, F-Box Proteins, Pioneer factor, Estrogen Receptor alpha, Ubiquitination, Cell Biology, NEDD4, 030104 developmental biology, HEK293 Cells, Nuclear receptor, Gene Expression Regulation, biology.protein, Demethylase, RNA, enhancer, CRISPR-Cas Systems, repression, Estrogen receptor alpha, 030217 neurology & neurosurgery, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d5c68e5687492448e4c65af6ad623bTest
https://escholarship.org/uc/item/3kg4h6pdTest

المؤلفون: Yue Ning, Xiaotong Su, Weiyi Zhang, Li Wang, Linsen Zan, Zainaguli Junjvlieke, Shijie Wang, Xue Mi, Xiaoyu Wang

المصدر: Molecular and Cellular Probes. 48:101443

مصطلحات موضوعية: Hepatocyte Nuclear Factor 3-alpha, Transcriptional Activation, Transcription, Genetic, Biology, 03 medical and health sciences, ANGPTL4, RNA interference, Transcription (biology), Adipocytes, Angiopoietin-Like Protein 4, Animals, Lipolysis, RNA, Messenger, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Lipoprotein lipase, Base Sequence, 030306 microbiology, Promoter, Cell Biology, Molecular biology, Lipoprotein Lipase, Enzyme, Adipose Tissue, Liver, chemistry, Mutation, Cattle

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406cc93711f3961399b61ab127a8da94Test
https://doi.org/10.1016/j.mcp.2019.101443Test

المؤلفون: Yu Liu, Xiang Zhang, Wei-Cong Huang, Lei Wang, Dezhi Cheng

المصدر: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 99

مصطلحات موضوعية: 0301 basic medicine, Hepatocyte Nuclear Factor 3-alpha, Lung Neoplasms, Down-Regulation, Apoptosis, Biology, medicine.disease_cause, TNF-Related Apoptosis-Inducing Ligand, 03 medical and health sciences, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, microRNA, medicine, Gene silencing, Humans, Lung cancer, Pharmacology, Oncogene, Base Sequence, General Medicine, medicine.disease, respiratory tract diseases, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Cancer research, Ectopic expression, FOXA1, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e855032a0612718bdb8a7a3004004d84Test
https://pubmed.ncbi.nlm.nih.gov/29665655Test

المؤلفون: Jeffrey A. Whitsett, David J. Picketts, Matías Alvarez-Saavedra, Kamal Bouhali, Siew-Lan Ang, Emmanouil Metzakopian

المصدر: Development (Cambridge, England)

مصطلحات موضوعية: Mouse, Mice, ChIP-Seq, Dopaminergic neuronal differentiation, Mesencephalon, Basic Helix-Loop-Helix Transcription Factors, RNA-Seq, Neurons, Genome, Otx Transcription Factors, Stem Cells, Neurogenesis, Dopaminergic, Gene Expression Regulation, Developmental, Cell Differentiation, Anatomy, Chromatin, 3. Good health, Cell biology, DNA-Binding Proteins, Ventral tegmental area, Enhancer Elements, Genetic, medicine.anatomical_structure, Hepatocyte Nuclear Factor 3-beta, Germ Layers, Protein Binding, Research Article, medicine.drug, Hepatocyte Nuclear Factor 3-alpha, Molecular Sequence Data, Mice, Transgenic, Nerve Tissue Proteins, Substantia nigra, Foxa1, Foxa2, Biology, Midbrain, Dopamine, medicine, Animals, Nucleotide Motifs, Molecular Biology, Floor plate, Homeodomain Proteins, Binding Sites, Base Sequence, Pars compacta, Dopaminergic Neurons, Cell Biology, Embryo, Mammalian, nervous system, Mutation, Transcription Factors, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6205f436c8eb3606ac9682e31e8f46dTest
https://doi.org/10.1242/dev.115808Test