التفاصيل البيبلوغرافية
| العنوان: |
Acute extrapyramidal syndromes in neuroleptic-treated elders: a pilot study. |
| المؤلفون: |
Ganzini, Linda, Heintz, Ronald, Hoffman, William F., Keepers, George A., Casey, Daniel E., Ganzini, L, Heintz, R, Hoffman, W F, Keepers, G A, Casey, D E |
| المصدر: |
Journal of Geriatric Psychiatry & Neurology; Oct1991, Vol. 4 Issue 4, p222-225, 4p |
| مصطلحات موضوعية: |
PARKINSON'S disease diagnosis, ANTIPSYCHOTIC agents, BASAL ganglia diseases, CHLORPROMAZINE, DOSE-effect relationship in pharmacology, NEUROLOGIC examination, PARKINSON'S disease, PSYCHOMOTOR disorders, TARDIVE dyskinesia, TARDIVE akathisia |
| مستخلص: |
The incidence, morbidity, and risk factors for acute extrapyramidal syndromes (EPS) such as akathisia and drug-induced parkinsonism (DIP) in neuroleptic-treated elders have not been systematically explored. This study presents data on 17 elderly patients who were prospectively examined for up to 4 weeks for acute EPS, functional and cognitive status, and behavioral disturbances. Seventy-one percent of subjects developed DIP, and 18% developed akathisia. Predictors of DIP included pre-neuroleptic treatment parkinsonian signs and neuroleptic dose, despite use of low doses of neuroleptics. Development of acute EPS was associated with failure to improve behaviorally. New-onset urinary incontinence was the most common functional abnormality. (J Geriatr Psychiatry Neurol 1991;4:222-225). [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |
