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المؤلفون: Thomas Laval, Sarah Saint-Auret, Ivo G. Boneca, Laurent Boucontet, Caroline Demangel, Jean-Pierre Levraud, Laure Guenin-Macé, Christophe Prehaud, Anaelle da Costa, Emma Colucci-Guyon, Aline Rifflet, Nicolas Blanchard
المساهمون: Macrophages et Développement de l’Immunité, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Biologie et Génétique de la Paroi bactérienne - Biology and Genetics of Bacterial Cell Wall, Laboratoire d'innovation moléculaire et applications (LIMA), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Neuro-Immunologie Virale - Viral Neuro-immunology, Immunobiologie de l'Infection - Immunobiology of Infection, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), This work was supported by the Institut Pasteur 'Microbes & Brain' collaborative project (LGM) and the Fondation Raoul Follereau (CD), core support from Institut Pasteur and INSERM (U1221). This study has received funding from the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (grant n °ANR-10-LABX-62-IBEID) (IGB). AR was support by a post-doctoral fellowship from the Laboratoire d’Excellence 'Integrative Biology of Emerging Infectious Diseases. T.L. was a BioSPC-Université Paris Diderot PhD student, recipient of doctoral fellowships from the Ministère français de l’Enseignement Supérieur, de la Recherche et de l’Innovation (2016–2019) and Fondation pour la Recherche Médicale (FDT201904008040)., We thank the Image Analysis Hub of the Institut Pasteur for help with image analysis. We are grateful to Laurent Marsollier for the malaysian human isolate M. ulcerans 1615 and to Tim Stinear for the bioluminescent strain of M.ulcerans., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008878 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩
PLoS Neglected Tropical Diseases, 2020, 14 (12), pp.e0008878. ⟨10.1371/journal.pntd.0008878⟩مصطلحات موضوعية: Central Nervous System, Bacterial Diseases, 0301 basic medicine, Buruli ulcer, Life Cycles, [SDV]Life Sciences [q-bio], RC955-962, Nervous System, chemistry.chemical_compound, Larvae, Medical Conditions, 0302 clinical medicine, Animal Cells, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, Zebrafish, biology, Optical Imaging, Eukaryota, Animal Models, 3. Good health, Cell biology, Actinobacteria, Infectious Diseases, medicine.anatomical_structure, Experimental Organism Systems, Osteichthyes, Blood-Brain Barrier, Larva, Mycobacterium ulcerans, Vertebrates, Physical Sciences, [SDV.IMM]Life Sciences [q-bio]/Immunology, Macrolides, Cellular Types, Anatomy, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Imaging Techniques, Materials Science, Material Properties, Bacterial Toxins, Central nervous system, Glial Cells, Research and Analysis Methods, Blood–brain barrier, Permeability, Cell Line, 03 medical and health sciences, Model Organisms, Spatio-Temporal Analysis, In vivo, Fluorescence Imaging, medicine, Animals, Humans, Microglial Cells, Bacteria, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Endothelial Cells, Cell Biology, Tropical Diseases, biology.organism_classification, medicine.disease, In vitro, Fish, 030104 developmental biology, chemistry, Astrocytes, Animal Studies, Zoology, 030217 neurology & neurosurgery, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ff524e2850e7ca4484b259cbe51f7eTest
https://doaj.org/article/26282b15277245c594cb443803d75fe7Test -
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المؤلفون: Joana Azeredo, Jorge Pedrosa, Hugo Alexandre Mendes Oliveira, Umender Sharma, Rita Silva-Gomes, Madhavi Hebbur, Alexandra G. Fraga, António G. Castro, Gabriela Trigo, Carine M. Gonçalves, Juan Dominguez, Ramya K. Murthy, Shamim Akhtar, Ana Rita Pacheco
المساهمون: Universidade do Minho
المصدر: PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007113 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Bacterial Diseases, 0301 basic medicine, Buruli ulcer, Physiology, Polymers, RC955-962, Lysin, Mycobacterium Bovis, chemistry.chemical_compound, 0302 clinical medicine, Immune Physiology, Arctic medicine. Tropical medicine, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, Materials, Mice, Inbred BALB C, Innate Immune System, biology, Animal Models, Antimicrobial, Recombinant Proteins, 3. Good health, Actinobacteria, Chemistry, Treatment Outcome, Infectious Diseases, Experimental Organism Systems, Macromolecules, Lytic cycle, Mycobacterium ulcerans, Physical Sciences, Cytokines, Female, Public aspects of medicine, RA1-1270, Research Article, Neglected Tropical Diseases, Ciências da Saúde [Ciências Médicas], Ciências Médicas::Ciências da Saúde, Immunology, Materials Science, 030231 tropical medicine, Mouse Models, Research and Analysis Methods, Microbiology, Mycobacterium tuberculosis, Interferon-gamma, 03 medical and health sciences, Bacteriolysis, Model Organisms, Endopeptidases, medicine, Animals, Animal Models of Disease, Science & Technology, Bacteria, Tumor Necrosis Factor-alpha, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Mycobacteriophages, Molecular Development, Peptidoglycans, Tropical Diseases, Polymer Chemistry, biology.organism_classification, medicine.disease, Disease Models, Animal, Animal Models of Infection, 030104 developmental biology, chemistry, Immune System, Animal Studies, Lymph Nodes, Peptidoglycan, Mycobacterium Tuberculosis, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8b6f18a58166f5c5fd774a22ff6b8cTest
https://doaj.org/article/be335171665840bbb480559a2a6a4957Test -
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المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0006745 (2019)مصطلحات موضوعية: 0301 basic medicine, Buruli ulcer, Bacterial Diseases, Endemic Diseases, Artificial Gene Amplification and Extension, Disease Vectors, Pathology and Laboratory Medicine, Mosquitoes, Polymerase Chain Reaction, law.invention, Geographical Locations, chemistry.chemical_compound, 0302 clinical medicine, law, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, DNA extraction, Polymerase chain reaction, Ulcers, Transmission (medicine), lcsh:Public aspects of medicine, Eukaryota, Gene Pool, Actinobacteria, Insects, Infectious Diseases, Mycobacterium ulcerans, Gene pool, Queensland, Research Article, Neglected Tropical Diseases, DNA, Bacterial, lcsh:Arctic medicine. Tropical medicine, Arthropoda, lcsh:RC955-962, 030231 tropical medicine, Oceania, Zoology, Mosquito Vectors, Biology, 03 medical and health sciences, Extraction techniques, Signs and Symptoms, Diagnostic Medicine, medicine, Genetics, Animals, Humans, Molecular Biology Techniques, Molecular Biology, Evolutionary Biology, Bacteria, Population Biology, Diptera, fungi, Public Health, Environmental and Occupational Health, Organisms, Australia, Biology and Life Sciences, lcsh:RA1-1270, biology.organism_classification, medicine.disease, Tropical Diseases, Invertebrates, Insect Vectors, Research and analysis methods, Species Interactions, 030104 developmental biology, chemistry, Vector (epidemiology), People and Places, Population Genetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16193c299df361de04098ba42ec66d8Test
https://pubmed.ncbi.nlm.nih.gov/30789904Test -
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المؤلفون: Paul D R Johnson, Till F. Omansen, Jason K. Axford, Sacha J. Pidot, Jessica L. Porter, Renee Marcsisin, Timothy P. Stinear, Kirstie M. Mangas, Brian O. Howden, Weiguang Zeng, John R. Wallace
المصدر: PLoS Neglected Tropical Diseases, Vol 11, Iss 4, p e0005553 (2017)
PLoS Neglected Tropical Diseases, 11(4). PUBLIC LIBRARY SCIENCE
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Bacterial Diseases, 0301 basic medicine, Buruli ulcer, SOUTHEASTERN AUSTRALIA, Disease Vectors, Skin infection, Mosquitoes, DISEASE, Geographical Locations, chemistry.chemical_compound, 0302 clinical medicine, NAUCORIS-CIMICOIDES, Aedes, MYCOLACTONE, Medicine and Health Sciences, BENIN, EPIDEMIOLOGY, Needlestick Injuries, Mycolactone, Buruli Ulcer, Mice, Inbred BALB C, biology, Infectious dose, lcsh:Public aspects of medicine, Animal Models, 3. Good health, Actinobacteria, Insects, Infectious Diseases, GHANA, Experimental Organism Systems, Mycobacterium ulcerans, Female, Research Article, Neglected Tropical Diseases, Skin Infections, lcsh:Arctic medicine. Tropical medicine, Arthropoda, lcsh:RC955-962, Oceania, 030231 tropical medicine, Mouse Models, Dermatology, Aedes aegypti, Aedes Aegypti, Research and Analysis Methods, Insect bites and stings, Microbiology, 03 medical and health sciences, Model Organisms, medicine, Animals, Bacteria, IDENTIFICATION, Organisms, Australia, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Insect Bites and Stings, lcsh:RA1-1270, Tropical Diseases, biology.organism_classification, medicine.disease, Invertebrates, ENVIRONMENTAL-SAMPLES, Insect Vectors, Species Interactions, 030104 developmental biology, chemistry, People and Places, RISK-FACTORS
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f1ae31d1a1a6da307d0791b98accc8Test
http://europepmc.org/articles/PMC5406025?pdf=renderTest -
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المؤلفون: Ekanao Tedihou, Gisela Bretzel, Marcus Beissner, Issaka Maman, Kossi Badziklou, Edith Nyaku, Franz Xaver Wiedemann, D. S. Karou, Komi Amekuse, Abiba Banla Kere, Tchadjobo Tchacondo
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 5, p e0006455 (2018)مصطلحات موضوعية: 0301 basic medicine, Buruli ulcer, Rural Population, Bacterial Diseases, Veterinary medicine, Marine and Aquatic Sciences, Artificial Gene Amplification and Extension, Skin infection, Polymerase Chain Reaction, law.invention, Geographical Locations, chemistry.chemical_compound, Feces, 0302 clinical medicine, law, Environmental Microbiology, Medicine and Health Sciences, Mycolactone, Buruli Ulcer, DNA extraction, Polymerase chain reaction, Soil Microbiology, lcsh:Public aspects of medicine, Actinobacteria, Infectious Diseases, Mycobacterium ulcerans, Togo, Soil microbiology, Plasmids, Research Article, Neglected Tropical Diseases, Freshwater Environments, DNA, Bacterial, lcsh:Arctic medicine. Tropical medicine, Livestock, lcsh:RC955-962, 030231 tropical medicine, Biology, Real-Time Polymerase Chain Reaction, Research and Analysis Methods, 03 medical and health sciences, Extraction techniques, Bacterial Proteins, Rivers, Surface Water, medicine, Genetics, Animals, Humans, Molecular Biology Techniques, Molecular Biology, Bacteria, Ecology and Environmental Sciences, Public Health, Environmental and Occupational Health, Organisms, Biology and Life Sciences, Aquatic Environments, lcsh:RA1-1270, Human Genetics, Bodies of Water, medicine.disease, biology.organism_classification, Tropical Diseases, 030104 developmental biology, chemistry, People and Places, Africa, DNA Transposable Elements, Earth Sciences, Hydrology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14afd95d3b985607b7c7f6d8ef9c7550Test
https://pubmed.ncbi.nlm.nih.gov/29782522Test -
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المؤلفون: Akira Kawashima, Junichiro En, Yoshito Kishi, Sho Kitamoto, Norihisa Ishii, Masamichi Goto, Suguru Yonezawa
المصدر: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005834 (2017)مصطلحات موضوعية: 0301 basic medicine, Buruli ulcer, Bacterial Diseases, Pathology, Macroglial Cells, Cytotoxicity, Apoptosis, Toxicology, Pathology and Laboratory Medicine, Epithelium, chemistry.chemical_compound, Mice, White Blood Cells, Animal Cells, Medicine and Health Sciences, Cytotoxic T cell, Mycolactone, Buruli Ulcer, Connective Tissue Cells, biology, Cell Death, lcsh:Public aspects of medicine, Animal Models, medicine.anatomical_structure, Infectious Diseases, Experimental Organism Systems, Connective Tissue, Cell Processes, Mycobacterium ulcerans, Macrolides, Cellular Types, Anatomy, Research Article, Neglected Tropical Diseases, medicine.medical_specialty, Programmed cell death, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Immune Cells, Bacterial Toxins, Immunology, Schwann cell, Glial Cells, Mouse Models, Research and Analysis Methods, Cell Line, 03 medical and health sciences, Model Organisms, medicine, Animals, Fibroblast, Blood Cells, Macrophages, Public Health, Environmental and Occupational Health, Biology and Life Sciences, Endothelial Cells, lcsh:RA1-1270, Epithelial Cells, Cell Biology, Fibroblasts, biology.organism_classification, medicine.disease, Tropical Diseases, 030104 developmental biology, Biological Tissue, chemistry, Schwann Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784ddceb801db41d8d6b80080449f355Test
https://pubmed.ncbi.nlm.nih.gov/28783752Test -
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المؤلفون: Isaac Darko Otchere, Dorothy Yeboah-Manu, Samuel Yaw Aboagye, Albert M. Liao, Thomas G. Caltagirone, Samuel Asamoah Sakyi
المصدر: PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0004950 (2016)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Bacterial Diseases, 0301 basic medicine, Buruli ulcer, Artificial Gene Amplification and Extension, Polymerase Chain Reaction, law.invention, chemistry.chemical_compound, 0302 clinical medicine, law, Zoonoses, Medicine and Health Sciences, Bovine Tuberculosis, Israel, Mycolactone, Buruli Ulcer, Polymerase chain reaction, biology, Mycobacterium smegmatis, lcsh:Public aspects of medicine, Aptamers, Nucleotide, Actinobacteria, Denaturation, Infectious Diseases, Mycobacterium ulcerans, Macrolides, Sequence Analysis, Research Article, Neglected Tropical Diseases, Tuberculosis, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Point-of-Care Systems, Aptamer, 030231 tropical medicine, Research and Analysis Methods, Sensitivity and Specificity, 03 medical and health sciences, Sequence Motif Analysis, medicine, Humans, Molecular Biology Techniques, Sequencing Techniques, Molecular Biology, Enzyme Assays, Bacteria, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, lcsh:RA1-1270, Tropical Diseases, biology.organism_classification, medicine.disease, Virology, RNA denaturation, 030104 developmental biology, ROC Curve, chemistry, Systematic evolution of ligands by exponential enrichment
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46088b6c818f83276e421d33a580375eTest
http://europepmc.org/articles/PMC5077154?pdf=renderTest -
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المؤلفون: Richard Phillips, Eveline van der Veer, Tjip S. van der Werf, Yves Thierry Barogui, Cleo van Diemen, Sandor-Adrian Klis, Ymkje Stienstra, Roch Christian Johnson
المساهمون: Translational Immunology Groningen (TRIGR), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Microbes in Health and Disease (MHD)
المصدر: PLoS Neglected Tropical Diseases, 10(4):e0004594. PUBLIC LIBRARY SCIENCE
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004594 (2016)
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Buruli ulcer, Male, Bacterial Diseases, Organic chemistry, Pathology and Laboratory Medicine, Gastroenterology, DISEASE, 0302 clinical medicine, Anti-Infective Agents, Antibiotics, MYCOLACTONE, INFECTION, Medicine and Health Sciences, ANTIMICROBIAL TREATMENT, 030212 general & internal medicine, Treatment Failure, Vitamin D, Buruli Ulcer, Cation Transport Proteins, Immune Response, Randomized Controlled Trials as Topic, biology, Antimicrobials, lcsh:Public aspects of medicine, Drugs, Vitamins, 3. Good health, Physical sciences, Actinobacteria, Chemistry, Infectious Diseases, Mycobacterium ulcerans, Streptomycin, MYCOBACTERIUM-ULCERANS, ANTIBIOTIC-TREATMENT, Female, medicine.symptom, Research Article, Neglected Tropical Diseases, VITAMIN-D DEFICIENCY, medicine.medical_specialty, Tuberculosis, lcsh:Arctic medicine. Tropical medicine, Genotype, lcsh:RC955-962, 030231 tropical medicine, Immunology, Radioimmunoassay, Genetic Predisposition, TUBERCULOSIS, Polymorphism, Single Nucleotide, Microbiology, vitamin D deficiency, Lesion, 03 medical and health sciences, Chemical compounds, Signs and Symptoms, Diagnostic Medicine, Internal medicine, Microbial Control, Organic compounds, medicine, Genetic predisposition, Vitamin D and neurology, Genetics, MANAGEMENT, Humans, Genetic Predisposition to Disease, CLINICAL-EFFICACY, Pharmacology, Bacteria, business.industry, Public Health, Environmental and Occupational Health, Organisms, Paradoxical reaction, Biology and Life Sciences, lcsh:RA1-1270, biology.organism_classification, medicine.disease, Tropical Diseases, Mycobacterium Ulcerans, Genetics of Disease, Lesions, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d338c26b1e71ffeb825837ff59576d5Test
https://hdl.handle.net/11370/50d879bd-5e48-4362-a9a3-b7a535d99e96Test -
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المؤلفون: Egídio Torrado, Wayne M. Meyers, Françoise Portaels, António G. Castro, Jorge Pedrosa, Margarida Saraiva, Andrea Cruz, Alexandra G. Fraga, Manuel T. Silva, Teresa G. Martins, Daniela Maria Ramos Pereira
المساهمون: Universidade do Minho
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAPمصطلحات موضوعية: Buruli ulcer, Time Factors, T-Lymphocytes, Apoptosis, Associations, Immune tolerance, Cytopathology, Mice, chemistry.chemical_compound, 0302 clinical medicine, Mycolactone, Lymph nodes, Migration, 0303 health sciences, Virulence, Bacterial Infections, Acquired immune system, 3. Good health, DNA-Binding Proteins, Vaccination, Infectious Diseases, Mycobacterium ulcerans, Female, Macrolides, Infection, Bacterial Toxins, Bacterial diseases, 030231 tropical medicine, Immunology, T cells, Mice, Nude, Biology, Microbiology, IFN-g, 03 medical and health sciences, Immune system, Immunity, Immune Tolerance, medicine, Animals, Mycolactones, 030304 developmental biology, Science & Technology, Systemic, CD4 lymphocyte count, Foci, biology.organism_classification, medicine.disease, chemistry, Parasitology, Immunosuppression
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2842d69ed11ec4d8207f0a9caeac7528Test
https://doi.org/10.1128/iai.00820-10Test -
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المؤلفون: Wayne M. Meyers, Douglas S. Walsh, Françoise Portaels
المصدر: Clinical Microbiology Newsletter. 31:119-127
مصطلحات موضوعية: Microbiology (medical), Buruli ulcer, Complications, Reemerging diseases, Epidemiology, Bacterial diseases, Pathogenesis, chemistry.chemical_compound, Diagnosis, medicine, BCG, Mycolactone, Mycobacterium ulcerans, biology, Transmission (medicine), business.industry, Incidence, Prevention, Osteomyelitis, medicine.disease, biology.organism_classification, Treatment, Vaccination, Clinical manifestations, Infectious Diseases, chemistry, Immunology, Osteitis, business, BCG vaccine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cd47e66315462115e02a1474b542e0Test
https://doi.org/10.1016/j.clinmicnews.2009.07.004Test
